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| 1 | Prevalence and predictors of hospitalization in Crohn's disease in a prospective population-based inception cohort from 2000-2012显示文摘AIM: To analyze the prevalence, length and predictors of hospitalization in the biological era in the populationbased inception cohort from Veszprem province.METHODS: Data of 331 incident Crohn's disease(CD) patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed(median age at diagnosis: 28; IQR: 21-40 years). Both in- and outpatient records were collected and comprehensively reviewed.RESULTS: Probabilities of first CD-related hospitalization and re-hospitalization were 32.3%, 45.5%,53.7% and 13.6%, 23.9%, 29.8%, respectively after one, three and five years of follow-up in Kaplan-Meier analysis. First-year hospitalizations were related to diagnostic procedures(37%), surgery or disease activity(27% and 21%). Non-inflammatory disease behavior at diagnosis(HR = 1.32, P = 0.001) and perianal disease(HR = 1.47, P = 0.04) were associated with time to first CD-related hospitalization, while disease behavior change(HR = 2.38, P = 0.002) and need for steroids(HR = 3.14, P = 0.003) were associated with time to first re-hospitalization in multivariate analyses.Early CD-related hospitalization(within the year of diagnosis) was independently associated with need for immunosuppressives(OR = 2.08, P = 0.001) and need for surgeries(OR = 7.25, P < 0.001) during the disease course.CONCLUSION: Hospitalization and re-hospitalization rates are still high in this cohort, especially during the first-year after the diagnosis. Non-inflammatory disease behavior at diagnosis was identified as the pivotal predictive factor of both hospitalization and rehospitalization. | Petra A Golovics Laszlo Lakatos Michael D Mandel Barbara D Lovasz Zsuzsanna Vegh Zsuzsanna Kurti Istvan Szita Lajos S Kiss Tunde Pandur Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，23： | 2 |
| 2 | Glutathione, altruistic metabolite in fungi 显示文摘 | Pocsi Istvan Prade Rolf A | 2004 | Advances in Microbial Physiology2004，49，： | 1 |
| 3 | Multisensory auditory-somatosensory interactions in early cortical processing revealed by high-density electrical mapping显示文摘 | Foxe John J Istvan A Murray Micah M | 2000 | Cognitive Brain Research2000，10，12： | 1 |
| 4 | Provably secure on- demand source routing in mobile Ad Hoc networks显示文摘 | GERGELY A C S LLEVENTE B ISTVAN V | 2006 | IEEE Trans- actions on Mobile Computin2006，5，11： | 1 |
| 5 | Syndrome aormalities and their change over time in a general population:data from an epidemiological study on the insulin resistance syndrome(DESIR)显示文摘 | Istvan S Beverley B Kettaneh A | | 0，，07： | 1 |
| 6 | Predictors of carpal tunnel syndrome: An l 1-year study of industrial workers 显示文摘 | Nathan P A Meadows K D Istvan J A | 2002 | J Hand Surg~2002，27，： | 1 |
| 7 | Effects of diabetes on oxidative and nitrosative stress in kidney mitochondria from aged rats显示文摘 | Rocío V. Pérez-Gallardo Ruth Noriega-Cisneros Edgar Esquivel-Gutiérrez Elizabeth Calderón-Cortés Christian Cortés-Rojo Salvador Manzo-Avalos Jesús Campos-García Rafael Salgado-Garciglia Rocío Montoya-Pérez Istvan Boldogh Alfredo Saavedra-Molina | 2014 | Journal of Bioenergetics and Biomembranes2014，，6： | 1 |
| 8 | Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells显示文摘 | Anne Friedrich Istvan A Krizbai | 2000 | Journal of Neurochemistry2000，74，3： | 1 |
| 9 | Grunberg SM (2009) Phase 2 trial results with the novel neurokinin-I receptor antagonist casopitant in combination with ondansetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting in cancer patients receiving moderately emetogenic chemotherapy显示文摘 | Wichit Istvan A Vincent LH | 2009 | Cancer2009，5，24： | 1 |
| 10 | a radomized,controlled molecular study of condylomata acuminate clearance during treatment with imiquimod显示文摘 | Tyring Istvan A | 1998 | J Infect Dis1998，178，： | 1 |
| 11 | Den- dritic polymer macromolecular carriers for drug deliv- ery显示文摘 | PATRI A K ISTVAN J M JAMES R B | 2002 | Curr Opin Chem Biol2002，6，： | 1 |
| 12 | Evaluation of mathematical models describing durg release fromlipophilic matrices显示文摘 | Judit D Istvan A | 1996 | Int J Pharm1996，145，1： | 1 |
| 13 | Rock mechanics for gas storage in bedded salt caverns显示文摘 | ISTVAN J A EVANS L J WEBER J H | 1997 | Int J Rock Mech Min Sci1997，34，： | 1 |
| 14 | Predictors of carpal tunnel syndrome: an 11-year study of industrial workers显示文摘 | Nathan P A Meadows K D Istvan J A | 2002 | J Hand Surg Am2002，27，4： | 1 |
| 15 | Wave propagation in a wooden bar显示文摘 | Istvan A Veres Mahir B Sayir | 2004 | Ultrasonic2004，，2： | 1 |
| 16 | Phase 2 trial results with the novel neurokinin-1 receptor antagonist casopitant in combination with ondansetron and dexamethasone for the prevention of chemothera- py-induced nausea and vomiting in cancer padents receiving mod- erately emetogenic chemotherapy显示文摘 | Wichit A Istvan A Vincent LH | 2009 | Cancer2009，115，24： | 1 |
| 17 | Isoforms of cathepsin D and human epidermal differentiation显示文摘 | Toshio H Istvan A Srinavasan R | 1998 | Biochimie1998，80，7： | 1 |
| 18 | Prorenin and Renin-Induced Extracellular Signal–Regulated Kinase 1/2 Activation in Monocytes Is Not Blocked by Aliskiren or the Handle-Region Peptide显示文摘 | Sandra Feldt Wendy W. Batenburg Istvan Mazak Ulrike Maschke Maren Wellner Heda Kvakan Ralf Dechend Anette Fiebeler Celine Burckle Aurelie Contrepas A H. Jan Danser Michael Bader Genevieve Nguyen Friedrich C. Luft Dominik N. Muller | 2008 | Hypertension2008，，3： | 1 |
| 19 | p66SHC inhibits the pro-survival EGFR/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells显示文摘 | Istvan A Amir F Yoshikuni N | 2008 | J Biol Chem2008，283，10： | 1 |
| 20 | Rock Mechan- ics for Gas Storage in Bedded Salt Caverns显示文摘 | Istvan J A Evans L J Weber J H | 1997 | Interna- tional Journal of Rock Mechanics and Mining Sciences1997，34，34： | 1 |
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