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| 1 | Laparoscopic splenectomy for splenic hamartoma:Case management and clinical consequences显示文摘Splenic hamartoma is a rare benign tumor,and although minimally invasive surgery may be suitable for this condition,there have only been 2 previous reports of laparoscopic surgery.Here we report the third case of splenic hamartoma managed by laparoscopic splenectomy.A 37-year-old male was incidentally diagnosed by abdominal ultrasonography with a hypoechoic mass measuring 2.5 cm × 2.4 cm in the spleen.Color Doppler sonography showed multiple flow signals within the mass and contrast-enhanced computed tomography revealed strong enhancement of the lesion.On T1-and T2-weighted magnetic resonance images,the splenic mass was demonstrated as isointense and hyperintense respectively.Although a malignant tumor could not be ruled out,a hand-assisted laparoscopic splenectomy was performed because the splenic mass was limited in size and had not invaded adjacent organs.The pathological diagnosis was splenic hamartoma.The postoperative course was uneventful and the patient was discharged by the seventh postoperative day.Although splenic hamartomas have some specific imaging features,more reports and analyses of these cases are required to increase the reliability of the diagnosis and management.Hand-assisted laparoscopic splenectomy may play a pivotal role in the postoperative diagnosis and management of this condition. | Tsutomu Namikawa Hiroyuki Kitagawa Jun Iwabu Michiya Kobayashi Manabu Matsumoto Kazuhiro Hanazaki | 2010 | World Journal of Gastrointestinal Surgery2010，2，4： | 4 |
| 2 | Epidermal growth factor induces fibroblast contractility and motil- ity via a protein kinase C -dependent pathway 显示文摘 | IWABU A SMITH K ALLEN F D | 2004 | The Journal of Biological Chemistry2004，279，14： | 1 |
| 3 | Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1显示文摘 | IWABU M YAMAUCHI T OKADA-IWABU M | 2010 | Nature2010，464，7293： | 1 |
| 4 | Adi- ponectin receptors:A review of their structure, func- tion and how they work显示文摘 | Yamauchi T Iwabu M Okada-Iwabu M | 2014 | Best Pract Res Clin En- docrinol Metab2014，28，1： | 1 |
| 5 | Com- bined analysis of cell growth and apoptosis-regulating pro- teins in HPVs associated anogenital tumors 显示文摘 | MITSUISHI T IWABU Y TOKUNAGA K | 2010 | BMC Cancer2010，10，： | 1 |
| 6 | Adiponectin re- ceptors: A review of their structure, function and how they work 显示文摘 | Yamauehi T Iwabu M Okada - Iwabu M | 2014 | Best Praet Res Clin Endocrinol Metab2014，28，1： | 1 |
| 7 | Clinicopathological proper-ties of the superficial spreading type early gastric cancer显示文摘 | Namikawa T Kitagawa H Iwabu J | 2010 | J Gas-trointest Surg2010，14，1： | 1 |
| 8 | A small moleculeAdipoR agonist for type 2 diabetes and short life in obesity显示文摘 | Okada Iwabu M Yamauchi T Iwabu M | 2013 | Nature2013，503，： | 1 |
| 9 | A small - mole- cule AdipoR agonist for type 2 diabetes and short life in obesity 显示文摘 | Okada - Iwabu M Yamauchi T Iwabu M | 2013 | Nature2013，503，7477： | 1 |
| 10 | A small-molecule AdipoR agonist for type 2 diabetes and short life inobesity 显示文摘 | Okada-Iwabu M Yamauchi T Iwabu M | 2013 | Nature2013，503，7477： | 1 |
| 11 | Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions显示文摘 | Yamauchi T Nio Y Maki T Kobayashi M Takazawa T Iwabu M | 2007 | Nat Med2007，13，： | 1 |
| 12 | Adiponectinand AdipoRl regulate PGC-1 alpha and mitochondria by Ca2 +and AMPK/SIRT1显示文摘 | Iwabu M Yamauchi T Okada-Iwabu M | 2010 | Nature2010，464，7293： | 1 |
| 13 | Adiponectin receptors: a review of their structure, function and how they work显示文摘 | Yamauchi T Iwabu M Okada-Iwabu M | 2014 | Best Pract Res Clin Endocrinol Metab2014，28，1： | 1 |
| 14 | Tumors arising at previous anastomotic site may have poor prognosis in pa- tients with gastric stump cancer following gastrectomy显示文摘 | Namikawa T Kitagawa H Iwabu J | 2010 | J Gastrointest Surg2010，14，12： | 1 |
| 15 | Adiponectin receptors: A review of their structure, function and how they work显示文摘 | Toshimasa Yamauchi Masato Iwabu Miki Okada-Iwabu Takashi Kadowaki | 2013 | Best Practice & Research Clinical Endocrinology & Metabolism2013，，： | 1 |
| 16 | Profiling of the com- pounds absorbed in human plasma and urine after oral adminis- tration of a traditional Japanese (kampo) medicine,daikenchu- to 显示文摘 | Iwabu J Watanabe J Hirakura K | 2010 | Drug Metabolism and Disposition2010，38，11： | 1 |
| 17 | A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations显示文摘 | Minako Imamura Shiro Maeda Toshimasa Yamauchi Kazuo Hara Kazuki Yasuda Takashi Morizono Atsushi Takahashi Momoko Horikoshi Masahiro Nakamura Hayato Fujita Tatsuhiko Tsunoda Michiaki Kubo Hirotaka Watada Hiroshi Maegawa Miki Okada-Iwabu Masato Iwabu Nobuhi | 2012 | Human Molecular Genetics2012，，13： | 1 |
| 18 | Pathophysiological roles of adipoR2 in endothelial ceils and adipoR1 in macrophages in the prevention of atherosclerosis 显示文摘 | Iwabu M O Yamauchi T Iwabu M | 2010 | Diabetes2010，59，1： | 1 |
| 19 | Adiponectin and Adi- poR1 regulate PGC - 1 alpha and mitoehondria by Ca^2+ and AMPK/SIRTI 显示文摘 | Iwabu M Yamauchi T Okada -lwabu M | 2010 | Nature2010，464，7293： | 1 |
| 20 | Inhibitory function of adapter-related protein complex 2 alpha 1 subunit in the process of nuclear translocation of human immunodeficiency virus type 1 genome显示文摘 | Yukiko Kitagawa Masanori Kameoka Sanae Shoji-Kawata Yukie Iwabu Hiroyuki Mizuta Kenzo Tokunaga Masato Fujino Yukikazu Natori Yoshiaki Yura Kazuyoshi Ikuta | 2007 | Virology2007，，1： | 1 |
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