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| 1 | Protective effects of Ginkgo biloba extract on the ethanol-induced gastric ulcer in rats显示文摘AIM: To evaluate the preventive effect of Ginkgo bilobaextract (GbE) on ethanol-induced gastric mucosal injuries in rats.METHODS: Female Wistar albino rats were used for the studies. We randomly divided the rats for each study into five subgroups: normal control, experimental control, and three experimental groups. The gastric ulcers were induced by instilling 1 mL 50% ethanol into the stomach. We gaveGbE 8.75, 17.5, 26.25 mg/kg intravenously to the experimental groups respectively 30 min prior to the ulcerative challenge. We removed the stomachs 45 min later. The gastric ulcers,gastric mucus and the content of non-protein sulfhydryl groups (NP-SH), malondialdehyde (MDA), c-Jun kinase (JNK) activity in gastric mucosa were evaluated. The amount of gastric juice and its acidity were also measured. RESULTS: The findings of our study are as follows: (1)GbE pretreatment was found to provide a dose-dependent protection against the ethanol-induced gastric ulcers in rats; (2) the GbE pretreatment afforded a dose-dependent inhibition of ethanol-induced depletion of stomach wall mucus, NP-SH oontents and increase in the lipid peroxidation (increase MDA) in gastric tissue; (3) gastric ulcer induced by ethanolproduced an increase in JNK activity in gastric mucosawhich also significantly inhibited by pretreatment with GbE;and (4) GbE alone had no inhibitory effect on gastric secretionin pylorus-ligated rats.CONCLUSION: The finding of this study showed that GbE significantly inhibited the ethanol-induced gastric lesions in rats. We suggest that the preventive effect of GbE may be mediated through: (1) inhibition of lipid peroxidation;(2) preservation of gastric mucus and NP-SH; and (3)blockade of cell apoptosis. | Sheng-Hsuan Chen Yu-Chih Liang Jane CJ Chao Li-Hsueh Tsai Chun-Chao Chang Chia-Chi Wang Shiann Pan | 2005 | World Journal of Gastroenterology2005，11，24： | 6 |
| 2 | Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation显示文摘 | Scott W. Biggins James Trotter Jane Gralla James R. Burton Kiran M. Bambha Jennifer Dodge Megan Brocato Linling Cheng Matt McQueen Lisa Forman Michael Chang Igal Kam Gregory Everson Richard A. Spritz Goran Klintmalm Hugo R. Rosen | 2013 | Journal of Hepatology2013，，5： | 2 |
| 3 | Intention to Obtain Human Papillomavirus Vaccination Among Taiwanese Undergraduate Women显示文摘 | Yu-Yun Hsu Susan Jane Fetzer Keng-Fu Hsu Yuan-Yuan Chang Chih-Pyng Huang Cheng-Yang Chou | 2009 | Sexually Transmitted Diseases2009，，11： | 1 |
| 4 | Event-Based Traceability for Managing Evolutionary Change显示文摘 | Carl K Chang Mark Christensen | 2003 | IEEE Trars on Software Engineering2003，29，9： | 1 |
| 5 | Chloroplast genome aberration in micropropagation derived albino Bambusa edulis mutants,ab1 and ab2 显示文摘 | Liu N T Jane W N Tsay H S Wu H Chang W C Lin C C | 2007 | Plant Cell Tissue and Organ Culture2007，88，2： | 1 |
| 6 | Mechanisms for Progenitor Cell-Mediated Repair for Ischemic Heart Injury显示文摘 | Shengwen Calvin Li Julyana Acevedo Lang Wang Hong Jiang Jane Luo Richard G. Pestell William G. Loudon Anthony C. Chang | 2012 | Current Stem Cell ResearchandTherapy2012，，1： | 1 |
| 7 | Differential protein expression of two photosystem II subunits,PsbO and PsbP,in an albino mutant of Bambusa edulis with chloroplast DNA aberration显示文摘 | Lin C S Liu N T Liao D C Yu J S Tsao H Lin C H Sun C W Jane W N Tsay H S Chen J J W Lai E M Lin N S Chang W C Lin C C | 2008 | AMER SOC Horticulture Science2008，133，2： | 1 |
| 8 | Postoperative Course and Hemodynamic Profile After the Arterial Switch Operation in Neonates and Infants. A Comparison of Low-Flow Cardiopulmonary Bypass and Circulatory Arrest显示文摘 | Gil Wernovsky David Wypij Richard A. Jonas John E. Mayer Frank L. Hanley Paul R. Hickey Amy Z. Walsh Anthony C. Chang Aldo R. Castaneda Jane W. Newburger David L. Wessel | 1995 | Circulation1995，，8： | 1 |
| 9 | Evaluation of analytical methods for determining pesticides in baby foods and adult duplicate-diet samples显示文摘 | Jane C Chuang Kathy Hart Joseph S Chang Lawrence E Boman Jeanette M Van Emon Allan W Reed | 2001 | Analytica Chimica Acta2001，，1： | 1 |
| 10 | Mechancial and physical properties of protein-starch based plastics produced by extrusion and injection molding显示文摘 | H C Huang T C Chang J Jane | 1999 | JAOCS1999，76，9： | 1 |
| 11 | Clinical fea- tures, diagnosis, and management of enterovirus 71显示文摘 | Ooi Mmong How Wong See Chang Lewthwaite Pen- ny Cardosa Mary Jane Solomon Tom | 2010 | Lancet Neurol2010，9，11： | 1 |
| 12 | Secondary metabolites from the leaves of Neolitsea hiiranensis and the anti- inflammatory activity of some of them 显示文摘 | Bi - Jiuan Liou Hsun - Shuo Chang Guei - Jane Wang el al | 2011 | Phytochemistry2011，72，5： | 1 |
| 13 | Comparison of Stem Cell Properties in Cell Populations Isolated From Human Central and Limbal Corneal Epithelium显示文摘 | Chuan-Yuan Ally Chang Jennifer Jane McGhee Colin Richard Green Trevor Sherwin | 2011 | Cornea2011，，10： | 1 |
| 14 | A synergic analysis for Web-based Enterprise Resource Planning Systems 显示文摘 | David C Yen David C Chou Jane Chang | 2002 | Computer Standards & Interfaces2002，24，： | 1 |
| 15 | Dietary vitamin E supplementation affects tissue lipid peroxidation of hybrid tilapia, Oreochromis niloticus x O -aureus 显示文摘 | Chenhuei Huang Ray Jane Chang Sulan Huang | 2003 | Comparative Biochemistry and Physiology Part B2003，134，2： | 1 |
| 16 | A three stage,fully differential 128 - 157 GHz CMOS amplifier withwide band matching 显示文摘 | Xu Zhiwei Gu Qun Jane Chang M C F | 2011 | IEEE Microwave and WirelessComponents Letters2011，21，10： | 1 |
| 17 | Evidence Utilisation Project: Management of Inadvertent Perioperative Hypothermia. The challenges of implementing best practice recommendations in the perioperative environment显示文摘 | Judy Munday Sonia Jane Hines Anne M Chang | 2013 | International Journal of Evidence‐Based Healthcare2013，，： | 1 |
| 18 | Ion-enhanced chemical etching of HfO2 for integration in metal-oxide-semiconductor field effect transistors显示文摘 | Sha Lir Ragesh Puthenkovilakam Lin Yousheng Chang Jane P | | 0，，： | 1 |
| 19 | Glucose-Regulated Protein 78 Is a Novel Contributor to Acquisition of Resistance to Sorafenib in Hepatocellular Carcinoma显示文摘 | Jeng-Fong Chiou MD Cheng-Jeng Tai MD Ming-Te Huang MD Po-Li Wei MD Yu-Huei Wang MS Jane An BS Chih-Hsiung Wu Tsan-Zon Liu PhD Yu-Jia Chang PhD | 2010 | Annals of Surgical Oncology2010，，2： | 1 |
| 20 | Evidence for neuronal expression of functional Fc (ε and γ) receptors显示文摘 | Hanneke van der Kleij Nicolas Charles Khalil Karimi Yu-Kang Mao Jane Foster Luke Janssen Ping Chang Yang Wolfgang Kunze Juan Rivera John Bienenstock | 2010 | The Journal of Allergy and Clinical Immunology2010，，3： | 1 |
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