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| 1 | Soil microbial biomass carbon and nitrogen in forest ecosystems of Northeast China:a comparison between natural secondary forest and larch plantation显示文摘Aims Natural secondary forest(NSF)and larch plantation are two of the predominant forest types in Northeast China.However,how the two types of forests compare in sustaining soil quality is not well understood.This study was conducted to determine how natural secondary forest and larch plantation would differ in soil microbial biomass and soil organic matter quality.Methods Microbial biomass carbon(MBC),microbial biomass nitrogen(MBN),soil organic carbon(SOC)and total nitrogen(TN)in the 0-to 15-cm and 15-to 30-cm soil layers were investigated by making chemical and biological measurements in the montane region of eastern Liaoning Province,Northeast China,during the growing season of 2008 in stands of NSF and Larix olgensis plantation(LOP).Important Findings We found that soil MBC and MBN were significantly lower in the LOP than in the NSF.Both MBC and MBN declined significantly with increasing soil depth in the two types of stands.The ratios of MBC to SOC(MBC/SOC)and MBN to TN(MBN/TN)were also significantly lower in the LOP than in the NSF.Moreover,the values of MBC,MBC/SOC,and MBN/TN significantly varied with time and followed a similar pattern during the growing season,all with an apparent peak in summer.Our results indicate that NSF is better in sustaining soil microbial biomass and nutrients than larch plantation in the temperate Northeast China.This calls for cautions in large-scale conversions of the native forests to coniferous plantations as a forest management practice on concerns of sustaining soil productivity. | Kai Yang Jiaojun Zhu Min Zhang Qiaoling Yan Osbert Jianxin Sun | 2010 | Journal of Plant Ecology2010，3，3： | 44 |
| 2 | Genetic analysis of 'all-fish' growth hormone gene transferred carp (Cyprinus carpio L.) and its F_1 generation显示文摘Recornbinant 'all-fish' growth hormone gene (GH) was microinjected into the fertilized eggs of carp. A comparison between the growth traits of transgenics and non-transgenics was carried out, and the transgenic individuals with significant 'fast-growing' effect were successfully gained. A comparison on the reproductivities was also given out between the transgenics and their non-transgenic siblings, and showed that the reproductive capacity of transgenics was substantially equivalent to those of the non-transgenics. On the other hand, the genetic separation and the characteristic distribution of the FI generation were genetically analyzed, which gave solid evidence for the hypothesis that 2-3 chromosomes are integrated with trans-gene. In addition, the distinct biological effects for multi-site-integrated transgenes were further discussed. The present study opens a door for the breeding of 'fast-growing' transgenic fish. | WANG Yaping, HU Wei, WU Gang,SUN Yonghua, CHEN Shangping, ZHANG Fuying,ZHU Zuoyan, FENG Jianxin & ZHANG Xirui1. State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China 2. Henan Institute of Aquaculture, Zhengzhou 450044, China | 2001 | Chinese Science Bulletin2001，46，14： | 23 |
| 3 | Changes in soil microbial biomass and community structure with addition of contrasting types of plant litter in a semiarid grassland ecosystem显示文摘Aims Elevated atmospheric CO_(2)has the potential to enhance the net primary productivity of terrestrial ecosystems.However,the role of soil microorganisms on soil C cycling following this increased available C remains ambiguous.This study was conducted to determine how quality and quantity of plant litter inputs would affect soil microorganisms and consequently C turnover.Methods Soil microbial biomass and community structure,bacterial community-level physiological profile,and CO_(2)emission caused by different substrate C decomposition were investigated using techniques of biological measurements,chemical and stable C isotope analysis,and BIOLOG-ECO microplates in a semiarid grassland ecosystem of northern China in 2006 and 2007 by mixing three contrasting types of plant materials,C_(3)shoot litter(SC_(3)),C_(3)root litter(RC_(3)),and C4 shoot litter(SC4),into the 10-to 20-cm soil layer at rates equivalent to 0(C0),60(C60),120(C120)and 240 g C m2(C240).Important Findings Litter addition significantly enriched soil microbial biomass C and N and resulted in changes in microbial structure.Principal component analysis of microbial structure clearly differentiated among zero addition,C_(3)-plant-derived litter,and C4-plant-derived litter and among shoot-and root-derived litter of C_(3)plants;soilmicroorganismsmainly utilized carbohydrates without litter addition,carboxylic acids with C_(3)-plant-derived litter addition and amino acidswith C4-plant-derived litter addition.We also detected stimulated decomposition of older substratewith C4-plant-derived litter inputs.Our results showthat both quality and quantity of belowground litter are involved in affecting soil microbial community structure in semiarid grassland ecosystem. | Hongmei Jin Osbert Jianxin Sun Jianfeng Liu | 2010 | Journal of Plant Ecology2010，3，3： | 18 |
| 4 | Targets and molecular mechanisms of triptolide in cancer therapy显示文摘Triptolide(TPL/TL) is a natural drug with novel anticancer effects. Preclinical studies indicated that TPL inhibits cell proliferation, induces cell apoptosis, inhibits tumor metastasis and enhances the effect of other therapeutic methods in various cancer cell lines. Multiple molecules and signaling pathways, such as caspases, heat-shock proteins, NF-κB, and deoxyribonucleic acid(DNA) repair-associated factors, are associated with the anti-cancer effect. TPL also improves chemoradiosensitivity in cancer therapy. Phase I trials indicate the potential clinical value of TPL use. However, further trials with larger sample sizes are needed to confirm these results. | Cuicui Meng Hongcheng Zhu Hongmei Song Zhongming Wang Guanhong Huang Defan Li Zhaoming Ma Jianhua Ma Qin Qin Xinchen Sun Jianxin Ma | 2014 | Chinese Journal of Cancer Research2014，26，5： | 16 |
| 5 | Constitutive relationship of IN690 superalloy by using uniaxial compression tests显示文摘The hot deformation behavior of IN690 superalloy was characterized in a temperature range of 1273-1473 K and a strain rate range of 0.01-10 s-1 using uniaxial compression tests on process annealed material.The constitutive relations between flow stress and effective strain,effective strain rate as well as deformation temperature were studied.It can be concluded that the flow stress significantly reduces with the deformation temperature of IN690 superalloy increasing.Whereas,there is a significant increase of flow stress when the strain rate increases from 0.1 s-1 to 10 s-1.Based on the hyperbolic-sine Arrhenius-type equation,a constitutive equation considering compensation of strain was developed.The activation energy and the material constants(Q,n and ln A) decrease as the deformation strain increases.The strain dependent term is successfully incorporated in the constitutive equation through a quartic equation.A good agreement between the experimental data and the predicted results has been achieved,indicating that the proposed constitutive equation and the methods of determing the material constants are suitable to model the high temperature deformation behavior of IN690 superalloy. | SUN Chaoyang LIU Jinrong LI Rui ZHANG Qingdong DONG Jianxin | 2011 | Rare Metals2011，30，1： | 11 |
| 6 | Contrasting responses of net primary productivity to inter-annual variability and changes of climate among three forest types in northern China显示文摘Aims A lack of explicit information on differential controls on net primary productivity(NPP)across regions and ecosystem types is largely responsible for uncertainties in global trajectories of terrestrial carbon balance with changing environment.The objectives of this study were to determine how NPP of different forest types would respond to inter-annual variability of climate and to examine the responses of NPP to future climate change scenarios across contrasting forest types in northern China.Methods We investigated inter-annual variations of NPP in relation to climate variability across three forest types in northern China,including a boreal forest dominated by Larix gmelinii Rupr.,and two temperate forests dominated by Pinus tabulaeformis Carr.and Quercus wutaishanica Mayr.,respectively,and studied the responses of NPP in these forests to predicted changes in climate for the periods 2011–40,2041–70 and 2070–100 under carbon emission scenarios A2 and B2 of Intergovernmental Panel on Climate Change.We simulated the responses of NPP to predicted changes in future climate as well as inter-annual variability of the present climate with the Biome-BGC version 4.2 based on site-and species-specific parameters.The modeled forest NPP data were validated against values in literature for similar types of forests and compared with inter-annual growth variations reflected by tree-ring width index(RWI)at the study sites.Important Findings Inter-annual variations in modeled NPP during the period 1960–06 were mostly consistent with the temporal patterns in RWI.There were contrasting responses of modeled NPP among the three forest types to inter-annual variability of the present climate as well as to predicted changes in future climate.The modeled NPP was positively related to annual mean air temperature in the L.gmelinii forest(P<0.001),but negatively in the P.tabulaeformis forest(P=0.05)and the Q.wutaishanica forest(P=0.03),while the relationships of modeled NPP with annual precipitation for the three forest types were all positive.Multiple stepwise regression analyses showed that temperature was a more important constraint of NPP than precipitation in the L.gmelinii forest,whereas precipitation appeared to be a prominent factor limiting the growth in P.tabulaeformis and Q.wutaishanica.Model simulations suggest marked,but differential increases in NPP across the three forest types with predicted changes in future climate. | Shuai Ouyang Xiangping Wang Yulian Wu Osbert Jianxin Sun | 2014 | Journal of Plant Ecology2014，7，3： | 9 |
| 7 | Mechanisms involved in antineuralgic effects of Paeonia Lactiflora: prediction based on network pharmacology显示文摘目的:白芍的镇痛作用已被广泛应用于中医临床,但对其潜在机制知之甚少.本研究旨在从网络药理学的角度阐明其有效成分和镇痛机制.方法:通过中药系统药理学分析平台(TCMSP)筛选出其可能的活性成分及CAS.从Pubchem 中获得其SMILES,并通过在Swiss Target Prediction 数据库中反向对接获得潜在的靶点.从GeenCards 数据库中提取疼痛相关分子,采用韦恩图筛选出芍药治疗疼痛的预测靶点.机制分析采用String 构建蛋白-蛋白相互作用,运用DAVID 平台进行靶点GO 功能富集和KEGG 信号通路富集.结果:通过GO 和KEGG 分析我们发现疼痛相关的信号通路主要涉及血清素能突触、钙信号通路、调控TRP 通道的炎症介质.利用基于网络的系统生物学和分子对接分析,我们预测了白芍中的11 种活性成分和97 个潜在的治疗靶标.PRKCA、CASP3、ALOX15、SLC6A4、PRKCG、ALOX5、PRKCB、ALOX12、 EGFR、ADRB2、RYR3、RYR1、NOS2、PTAFR、PRKCQ、PRKCD 等基因参与了白芍的镇痛作用.结论:白芍可通过调节TRP 通道炎症介质、钙信号通路和5-羟色胺受体减轻疼痛.PRKCA、PRKCB、PRKCD、 PRKCQ 和PRKCG 可能是疼痛治疗的新靶标. | Di Zhang Shengsuo Ma Jianxin Sun Bing Yang Haoming Lin Meijing Xie Meina Huang Guoping Zhao | 2019 | TMR Clinical Research2019，2，2： | 8 |
| 8 | An Efficient and Stable Ionic Liquid System for Synthesis of Ethylene Glycol via Hydrolysis of Ethylene Carbonate显示文摘An ionic liquid system of [Bmim]X/[Bmim]OH(X Cl,BF4,and PF6,) was developed for the hydroly-sis of ethylene carbonate to ethylene glycol. The important parameters,such as the variety of ionic liquids,molar ratio of [Bmim]X to [Bmim]OH,amount of ionic liquid,molar ratio of water to ethylene carbonate,reaction tem-perature,pressure and reaction time,were investigated systematically. Excellent yield(>93%) and high selectivity(99.5%) of ethylene glycol were achieved. Under the optimum reaction conditions,the ionic liquid system could be reused at least five times and the selectivity of ethylene glycol remained higher than 99.5%. | MENG Zhenying SUN Jian WANG Jinquan ZHANG Jianxin FU Zengzeng CHENG Weiguo ZHANG Xiangping | 2010 | Chinese Journal of Chemical Engineering2010，18，6： | 8 |
| 9 | Formaldehyde induces toxic effects and regulates the expression of damage response genes in BM-MSCs显示文摘在这研究,我们在老鼠骨头髓上估计了甲醛(FA ) 的有毒的效果间充质的干细胞(BM-MSCs ) 。Cytotoxicity 被使用 MTT 试金测量。DNA 海滨破裂被与朊酶 K (PK ) 修改的标准碱的彗星试金和彗星试金检测。DNAprotein 交叉连接(DPC ) 被 KCl-SDS 降水试金检测。我们发现在从 75 ~ 200 M 的集中的 FA 禁止了房间幸存并且在 125 M 上导致了 DPC。修改 PK 的彗星试金证明那导致 FA 的 DNA 海滨破裂从 75 ~ 200 M 以一种剂量依赖者方式被增加。在另一方面,标准碱的彗星试金证明那 DNA 海滨破裂在 125 M 上与 FA 集中被减少。我们由使用在 DPC 和幸存率之间有否定线性关联的皮尔森关联证实了(r = 0.987, P < 0.01 ) 并且在 DPC 和(i) 姐妹染色单体交换之间的积极线性关系并且(ii ) micronucleus (r = 0.995, P < 0.01;r = 0.968, P < 0.01 ) 。DNA 损坏 RT2 剖析程序聚合酶链反应数组被用来在损坏反应基因的表达式调查变化。相应再结合小径的核苷酸切除修理小径和 Brca2, Rad51,和 Xrcc2 的 Xpa 和 Xpc 都在 75 和 125 M FA 是起来调整的。然而,一样的基因与 175 M FA 是下面调整的。Chek1 和 Hus1 的表情,涉及房间周期规定,与 75, 125,和 175 M FA 以一样的方式被改变。这些结果显示 Xpa, Xpc, Brca2, Rad51, Xrcc2, Chek1,和 Hus1 是必要的让 BM-MSCs 抵抗 FA 的效果。 | Yali She Yi Li Yongqi Liu Guli Asai Shaobo Sun Jianxin He Zheng Pan Yan Cui | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 8 |
| 10 | CROWN:A service grid middleware with trust management mechanism显示文摘Based on a proposed Web service-based grid architecture, a service grid middleware system called CROWN is designed in this paper. As the two kernel points of the middleware, the overlay-based distributed grid resource management mechanism is proposed, and the policy-based distributed access control mechanism with the capability of automatic negotiation of the access control policy and trust management and negotia- tion is also discussed in this paper. Experience of CROWN testbed deployment and ap- plication development shows that the middleware can support the typical scenarios such as computing-intensive applications, data-intensive applications and mass information processing applications. | HUAI Jinpeng HU Chunming LI Jianxin SUN Hailong WO Tianyu | 2006 | Science in China(Series F)2006，49，6： | 8 |
| 11 | Structure of the Upper Mantle and Transition Zone Beneath the South China Block Imaged by Finite Frequency Tomography显示文摘We applied the finite frequency tomography method to S wave data recorded by 350 broadband stations beneath the South China Block(SCB) and its surroundings from earthquakes occurring between July 2007 and July 2010,to better understand upper mantle deformation.Differential travel-times in the pair of stations with appropriate weighting for each station are used in the inversion.Our results are consistent with previous tomography that show a high velocity anomaly beneath the Sichuan basin and a high velocity anomaly in the transition zone beneath the Yangtze Craton.However,the resolution of mantle heterogeneity provides new insight into the tectonic framework of subduction of Burmese lithosphere in the west part of the study region and subduction of oceanic lithosphere in the east.In the subduction realm,west of 107°E,a significant fast S-wave anomaly is located on the southeast of Sichuan Basin.East of 107°E,and two narrow and discontinuous fast S-wave anomalies occur at a depth of 400-600 km beneath the middle of the South China block overlain by the pronounced low S-wave anomalies at a depth of 100 and 400 km.If the fast anomalies located in the mantle transition zone represent stagnant slabs,their fragmented nature may suggest that they could be produced by different episodes of subduction beneath western Pacific island and the above slow velocity anomaly may associated with the back-arc regions of ongoing subduction.In addition,tomography also reveals an anomalously high S-wave velocity continental root extends eastward to a depth 400 km beneath the eastern Sichuan Basin.This anomaly may be related to eastern extrusion of Indian lithosphere associated with the collision of India and Eurasia.Moreover,our results also show large slow anomalies beneath the Red River fault region connected to deeper anomalies beneath the South China Fold Belt and South China Sea.AH these observations are consistent with the scenario that the South China block has been built by both of subduction of Paleopacific plate and eastward subduction of Burma microplate. | SUN Ya LIU Jianxin TANG Youcai CHEN Jiawei ZHOU Keping CHEN Bo | 2016 | Acta Geologica Sinica(English Edition)2016，90，5： | 8 |
| 12 | Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types显示文摘 | Shifang Ren Zejian Zhang Congjian Xu Lin Guo Renquan Lu Yihong Sun Jianming Guo Ruihuan Qin Wenjun Qin Jianxin Gu | 2016 | Cell Research2016，26，8： | 8 |
| 13 | Novel Recombinant Seneca Valley Virus Isolated from Slaughtered Pigs in Guangdong Province显示文摘Dear Editor,Since the first outbreak in Brazil in 2015,Seneca Valley virus(SVV)associated with porcine idiopathic vesicular disease,has shown increasing geographic distribution.Cases of SVV have been reported from several countries including the United States(US),Colombia,Thailand,Canada,and China(Pasma et al.2008;Zhang et al.2015;Sun et al.2017;Wu et al.2017;Liu et al.2018;Saeng-Chuto et al.2018).SVV was first identified in the US in 2002 and is the only member of the genus Senecavirus in the family Picomaviridae(Hales et al.2008;Leme et al.2017).The SVV genome contains a large open reading frame(ORF)encoding a polyprotein,which is cleaved into various mature viral proteins including the leader protein(L),structural proteins(VP1,VP2,VP3,and VP4),and non-structural proteins(2A,2B,2C,3A,3B,3C,and 3D)(Hales et al 2008).Structural proteins bind to their receptor,anthrax toxin receptor 1,to mediate viral invasion and stimulate specific immunity of the host(Jayawardena et al.2018).Non-structural proteins such as 3C suppress innate immune responses by degrading interferon regulatory factor 3(IRF 3)and IRF7 and inhibit the activation of RIG-1,TBK1,and TRAF3 through deubiquitination(Xue et al 2018). | Jianxin Liu Yunfeng Zha Huizi Li Yanwei Sun Fuguang Wang Rong Lu Zhangyong Ning | 2019 | Virologica Sinica2019，34，6： | 7 |
| 14 | Distribution and Ecological Risk Assessment of HCHs and DDTs in Surface Seawater and Sediment of the Mariculture Area of Jincheng Bay,China显示文摘The distribution of hexachlorocyclohexanes(HCHs) and dichlorodiphenyltrichloroethanes(DDTs) in the surface seawater and sediment of Jincheng Bay mariculture area were investigated in the present study. The concentration of total HCHs and DDTs ranged from 2.98 to 14.87 ng L-1 and were < 0.032 ng L-1, respectively, in surface seawater, and ranged from 5.52 to 9.43 and from 4.11 to 6.72 ng g-1, respectively, in surface sediment. It was deduced from the composition profile of HCH isomers and DDT congeners that HCH residues derived from a mixture of technical-grade HCH and lindane whereas the DDT residues derived from technical-grade DDT and dicofol. Moreover, both HCH and DDT residues may mainly originate from historical inputs. The hazard quotient of α-HCH, β-HCH, γ-HCH and δ-HCH to marine species was 0.030, 0.157, 3.008 and 0.008, respectively. It was estimated that the overall probability of adverse biological effect from HCHs was less than 5%, indicating that its risk to seawater column species was low. The threshold effect concentration exceeding frequency of γ-HCH, p,p'-DDD, p,p'-DDE and p,p'-DDT in sediment ranged from 8.3% to 100%, and the relative concentration of the HCH and DDT mixture exceeded their probable effect level in sediment. These findings indicated that the risk to marine benthos was high and potentially detrimental to the safety of aquatic products, e.g., sea cucumber and benthic shellfish. | HU Yanbing SUN Shan SONG Xiukai MA Jianxin RU Shaoguo | 2015 | Journal of Ocean University of China2015，14，2： | 7 |
| 15 | Effects of Sini San used alone and in combination with fluoxetine on central and peripheral 5-HT levels in a rat model of depression显示文摘OBJECTIVE: To investigate the effects of Sini San and fluoxetine on the levels of central and peripheral 5-HT in a rat model of depression, and provide new insight into the treatment of depression with integrated Chinese-Western Medicine.METHODS: A rat model of depression was established by chronic mild stress(CMS). Model rats received either Sini San, fluoxetine, a combination of the two drugs, or no drug treatment. Healthy naive rats were used as controls. Open field and sucrose preference tests were used to assess depression-like behavior. ELISA and immunohistochemistry were used to determine central and peripheral levels of 5-HT.RESULTS: In the group with no drug treatment,central 5-HT expression decreased while peripheral5-HT concentrations increased as CMS continued.Four weeks after CMS, Sini San alone was less effective in reducing depression-like behavior than fluoxetine alone or in combination with Sini San,but combined use was more effective than fluoxetine alone. Eight weeks after CMS, Sini San alone or in combination with fluoxetine was more effective in reducing depression-like behavior than fluoxetine alone. Furthermore Sini San and fluoxetine used alone or in combination notably increased central 5-HT expression and decreased peripheral 5-HT levels in the rat model.CONCLUSION:The results of the present study indicate that there is a synergistic action between the two medicines in the treatment of depression. Sini San exhibited a relatively long lag before its effects were observed; however, by eight weeks the Traditional Chinese Medicine appeared at least as effective as fluoxetine. We suggest that Sini San can replace fluoxetine in the later stages of depression treatment to minimize side effects observed with long-term fluoxetine administration. | Yubo Li Yuxiu Sun Xueling Ma Xiaoxing Xue Wenting Zhang Zhiqian Wu Yulin Ouyang Jianxin Chen Weiming Wang Shuzhen Guo Wei Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 6 |
| 16 | Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death显示文摘细胞毒素的淋巴细胞是在有缺点的房间的有免疫力的反应和消除的组织的关键播放器。我们以前报导了生来的杀手(NK ) 房间进入目标肿瘤房间,导致在肿瘤房间以内的任何一个目标房间死亡或自我毁灭。然而,它留下了至于在成为主观以后的 NK 房间的命运逃犯并且 heterotypic cell-in-cell 过程最近是否与同型的 cell-in-cell 事件的不同,说出 entosis。这里,我们证明 NK 房间在肿瘤房间以内与 apoptosis 的最终的命运经历一个 cell-in-cell 过程并且表明成为主观过程要求肌动朊细胞骨架管理者, ezrin。设想 NK 房间怎么进入肿瘤房间,我们执行了 NK 房间成为主观的即时双颜色成像分析进肿瘤房间。令人惊讶地,大多数 NK 房间在他们的入口以后承诺规划房间死亡进肿瘤房间,它与在同型的 cell-in-cell 过程观察的 entosis 区别地不同。使内在化的 NK 房间的 apoptotic 房间死亡由 caspase 的激活是明显的 3 并且 DNA 破碎。而且,在成为主观以后的 NK 房间死亡被 caspase 禁止者稀释, Z-VAD-FMK,在肿瘤房间以内作为 NK 房间死亡的模式证实 apoptosis。决定为 NK 房间的入口必要的蛋白质因素进肿瘤房间,我们执行了基于 siRNA 的击倒的分析并且在 NK 房间成为主观发现了 ezrin 的一个关键角色。重要地, ezrin 的调停 PKA 的 phosphorylation 支持 NK 房间成为主观过程。我们的调查结果建议 ezrin 由管理 NK 房间成为主观进肿瘤房间的新奇规章的机制。 | Shan Wang Zhen Guo Peng Xia Tingting Liu Jufang Wang Shan Li Lihua Sun Jianxin Lu Qian Wen Mingqian Zhou Li Ma Xia Ding Xiaoning Wang Xuebiao Yao | 2009 | Cell Research2009，19，12： | 6 |
| 17 | Variations in leaf litter decomposition across contrasting forest stands and controlling factors at local scale显示文摘Aims litter decomposition is a critical pathway linking the above-and belowground processes.However,factors underlying the local spatial variations in forest litter decomposition are still not fully addressed.We investigated leaf litter decomposition across con-trasting forest stands in central China,with objective to determine the spatial variations and controlling factors in forest floor leaf lit-ter decomposition in relation to changes in forest stands in a tem-perate forest ecosystem.Methods leaf litter decomposition was studied by using litterbag method across several typical forest stand types in baotianman Nature reserve,central China,including pure stands of Quercus aliena var.acuteserrata,Q.glandulifera var.brevipetiolata and Q.vari-abilis,respectively,and mixed pine/oak stands dominated by Pinus armandii and Q.aliena var.acuteserrata,as well as stands of pure Q.aliena var.acuteserrata trees ranging in stand age from~40 to>160 years.measurements were made on litter mass remaining and changes in litter chemistry during decomposition over a 2-year period,along with data collections on selective biotic and environmental factors.a reciprocal transplant experiment involv-ing Q.aliena var.acuteserrata and Q.variabilis was concurrently carried out to test the occurrence of‘home-field advantage(HFa)’in local forests when only considering contrasting oak tree spe-cies.Correlation analyses and path analyses were performed to identify the dominant drivers and their relative contributions to variations in leaf litter decomposition.Important findingssignificant variations were found in the rate of leaf litter decomposi-tion among stands of different tree species but not among stand age classes.The values of decay constant,k,varied from 0.62 in Q.aliena var.acuteserrata stands to 0.56 in Q.variabilis stands.The reciprocal litter transplant experiment showed that the rate of leaf litter decom-position was on average 5%slower in home-fields than on recipro-cal sites.Path analysis identified litter acid-unhydrolyzable residue(AUR)to N ratio,soil microbial biomass carbon(MBC),soil pH and soil organic carbon(SOC)as most prominent factors controlling the rate of leaf litter decomposition,collectively accounting for 57.8%of the variations;AUR/N had the greatest negative effect on k value,followed by weaker positive effects of SOC and MBC.our findings suggest that tree species plays a primary role in affecting forest floor leaf litter decomposition by determining the litter quality,with site environment being a secondary factor contributing to the local vari-ations in leaf litter decomposition in this temperate forest ecosystem. | Juan Wang Yeming You Zuoxin Tang Shirong Liu Osbert Jianxin Sun | 2015 | Journal of Plant Ecology2015，8，3： | 6 |
| 18 | Two optimization algorithms for solving robotics inverse kinematics with redundancy显示文摘The kinematic redundancy in a robot leads to an infinite number of solutions for inverse kinematics, which implies the possibility to select a 'best' solution according to an optimization criterion. In this paper, two optimization objective functions are proposed, aiming at either minimizing extra degrees of freedom (DOFs) or minimizing the total potential energy of a multilink redundant robot. Physical constraints of either equality or inequality types are taken into consideration in the objective functions. Since the closed-form solutions do not exist in general for highly nonlinear and constrained optimization problems, we adopt and develop two numerical methods, which are verified to be effective and precise in solving the two optimization problems associated with the redundant inverse kinematics. We first verify that the well established trajectory following method can precisely solve the two optimization problems, but is computation intensive. To reduce the computation time, a sequential approach that combines the sequential quadratic programming and iterative Newton-Raphson algorithm is developed. A 4-DOF Fujitsu Hoap-1 humanoid robot arm is used as a prototype to validate the effectiveness of the proposed optimization solutions. | Jianxin XU, Wei WANG, Yuanguang SUN (Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117576) | 2010 | 控制理论与应用(英文版)2010，8，2： | 5 |
| 19 | Tat-functionalized Ag-Fe_3O_4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery显示文摘In this paper, we prepared a dual functional system based on dextrin-coated silver nanoparticles which were further attached with iron oxide nanoparticles and cell penetrating peptide(Tat), producing Tat-modified Ag-Fe_3O_4 nanocomposites(Tat-FeAgNPs). To load drugs, an –SH containing linker, 3-mercaptopropanohydrazide, was designed and synthesized. It enabled the silver carriers to load and release doxorubicin(Dox) in a pH-sensitive pattern. The delivery efficiency of this system was assessed in vitro using MCF-7 cells, and in vivo using null BalB/c mice bearing MCF-7 xenograft tumors. Our results demonstrated that both Tat and externally applied magnetic field could promote cellular uptake and consequently the cytotoxicity of doxorubicin-loaded nanoparticles,with the IC_(50) of Tat-FeAgNP-Dox to be 0.63 mmol/L. The in vivo delivery efficiency of Tat-FeAgNP carrying Cy5 to the mouse tumor was analyzed using the in vivo optical imaging tests, in which TatFeAgNP-Cy5 yielded the most efficient accumulation in the tumor(6.772.4% ID of Tat-FeAgNPs).Anti-tumor assessment also demonstrated that Tat-FeAgNP-Dox displayed the most significant tumor-inhibiting effects and reduced the specific growth rate of tumor by 29.6%(P ? 0.009), which could be attributed to its superior performance in tumor drug delivery in comparison with the control nanovehicles. | Ergang Liu Meng Zhang Hui Cui Junbo Gong Yongzhuo Huang Jianxin Wang Yanna Cui Weibing Dong Lu Sun Huining He Victor C.Yang | 2018 | Acta Pharmaceutica Sinica B2018，8，6： | 5 |
| 20 | Application of two remote sensing GPP algorithms at a semiarid grassland site of North China显示文摘Estimation of gross primary production(GPP)from remote sensing data is an important approach to study regional or global carbon cycle.However,for a given algorithm,it usually has its limitation on applications to a wide range of vegetation types and/or under diverse environmental conditions.This study was conducted to compare the performance of two remote sensing GPP algorithms,the MODIS GPP and the vegetation photosynthesis model(VPM),in a semiarid temperate grassland ecosystem.Methods The study was conducted at a typical grassland site in Ujimuqin of Inner Mongolia,North China,over 2 years in 2006 and 2007.Environmental controls on GPP measured by the eddy covariance(EC)technique at the study site were first investigated with path analysis of meteorological and soil moisture data at a daily and 8-day time steps.The estimates of GPP derived from the MODIS GPP and the VPM with site-specific inputs were then compared with the values of EC measurements as ground truthing at the site.Site-specific emax(a)was estimated by using rectangular hyperbola function based on the 7-day flux data at 30-min intervals over the peak period of the growing season(May to September).Important Findings Between the two remote sensing GPP algorithms and various estimates of the fraction of absorbed photosynthetic active radiation(FPAR),the VPM based on FPAR derived from the enhanced vegetation index(EVI)works the best in predicting GPP against the ground truthing of EC GPP.A path analysis indicates that the EC GPP in this semiarid temperate grassland ecosystem is controlled predominantly by both soil water and temperature.The site water condition is slightly better simulated by the moisture multiplier in the VPM than in the MODIS GPP algorithm,which is a most probable explanation for a better performance of the VPM than MODIS GPP algorithm in this semiarid grassland ecosystem. | Jianfeng Liu Osbert Jianxin Sun Hongmei Jin Zhiyong Zhou Xingguo Han | 2011 | Journal of Plant Ecology2011，4，4： | 5 |
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