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| 1 | Meso–Cenozoic Tectono-Thermal Evolution History in Bohai Bay Basin, North China显示文摘The thermal history of sedimentary basins is a key factor for hydrocarbon accumulation and resource assessment, and is critical in the exploration of lithospheric tectono-thermal evolution. In this paper, the Cenozoic thermal histories of nearly 200 wells and the Mesozoic thermal histories of 15 wells are modeled based on the vitrinite reflectance and apatite fission track data in Bohai Bay Basin, North China. The results show that the basin experienced Early Cretaceous and Paleogene heat flow peaks, which reveals two strong rift tectonic movements that occurred in the Cretaceous and the Paleogene in the basin, respectively. The thermal evolution history in Bohai Bay Basin can be divided into five stages including(1) the low and stable heat flow stage from the Triassic to the Jurassic, with the heat flow of 53 to 58 m W/m2;(2) the first heat flow peak from the Early Cretaceous to the middle of the Late Cretaceous, with a maximum heat flow of 81 to 87 m W/m2;(3) the first post-rift thermal subsidence stage from the middle of the Late Cretaceous to the Paleocene, with the heat flow of 65 to 74 m W/m2 at the end of the Cretaceous;(4) the second heat flow peak from the Eocene to the Oligocene, with a maximum heat flow of 81 to 88 m W/m2; and(5) the second thermal subsidence stage from the Neogene to present, with an average heat flow of 64 m W/m2. | Yinhui Zuo Nansheng Qiu Jiawei Li Qingqing Hao Xiongqi Pang Zhongying Zhao Qi Zhu | 2015 | Journal of Earth Science2015，26，3： | 6 |
| 2 | Unmanned Aerial Vehicles:Control Methods and Future Challenges显示文摘With the rapid development of computer technology,automatic control technology and communication technology,research on unmanned aerial vehicles(UAVs)has attracted extensive attention from all over the world during the last decades.Particularly due to the demand of various civil applications,the conceptual design of UAV and autonomous flight control technology have been promoted and developed mutually.This paper is devoted to providing a brief review of the UAV control issues,including motion equations,various classical and advanced control approaches.The basic ideas,applicable conditions,advantages and disadvantages of these control approaches are illustrated and discussed.Some challenging topics and future research directions are raised. | Zongyu Zuo Cunjia Liu Qing-Long Han Jiawei Song | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，4： | 4 |
| 3 | Transcriptomics and metabolomics analyses provide insights into postharvest ripening and senescence of tomato fruit under low temperature显示文摘Tomato is one of the most important vegetable crops in the world and is a model plant used to study the ripening of climacteric fleshy fruit.During the ripening process of tomato fruit,flavor and aroma metabolites,color,texture and plant hormones undergo significant changes.However,low temperatures delayed the ripening process of tomato fruit,inhibiting flavor compounds and ethylene production.Metabolomics and transcriptomics analyses of tomato fruit stored under low temperature(LT,5°C)and room temperature(RT,25°C)were carried out to investigate the effects of storage temperature on the physiological changes in tomato fruit after harvest.The results of transcriptomics changes revealed that the differentially expressed genes(DEGs)involved in tomato fruit ripening,including several kinds of transcription factors(TFs)(TCP,WRKY,MYB and bZIP),enzymes involved in cell wall metabolism[beta-galactosidase(β-GAL),pectinesterase(PE)and pectate lyase(PL),cellulose and cellulose synthase(CESA)],enzymes associated with fruit flavor and aroma[acetyltransferase(AT),malic enzyme(ME),lipoxygenase(LOX),aldehyde dehydrogenase(ALDH),alcohol dehydrogenase(ADH)and hexokinase(HK)],genes associated with heat stress protein 70 and genes involved in the production of plant hormones such as Ethylene responsive factor 1(ERF1),Auxin/indoleacetic acids protein(AUX/IAA),gibberellin regulated protein.Based on the above results,we constructed a regulatory network model of the effects of different temperatures during the fruit ripening process.According to the analysis of the metabolomics results,it was found that the contents of many metabolites in tomato fruit were greatly affected by storage temperature,including,organic acids(L-tartaric acid,a-hydroxyisobutyric acid and 4-acetamidobutyric acid),sugars(melezitose,beta-Dlactose,D-sedoheptulose 7-phosphate,2-deoxyribose 1-phosphate and raffinose)and phenols(coniferin,curcumin and feruloylputrescine).This study revealed the effects of storage temperature on postharvest tomato fruit and provided a basis for further understanding of the molecular biology and biochemistry of fruit ripening. | Chunmei Bai Caie Wu Lili Ma Anzhen Fu Yanyan Zheng Jiawei Han Changbao Li Shuzhi Yuan Shufang Zheng Lipu Gao Xinhua Zhang Qing Wang Demei Meng Jinhua Zuo | 2023 | Horticultural Plant Journal2023，9，1： | 3 |
| 4 | Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist显示文摘Blockade of the interaction of anaphylatoxin C5a with its receptor C5aR1 has been actively studied as a potential treatment for many inflammatory diseases;but current C5a antagonists exhibit inadequate potency and poor species cross-reactivity, and novel biochemical tools are needed to investigate whether the core region of C5a contains important interaction epitopes that can explain these limitations. Herein, we report the development of chimeric protein C5a probes containing both the complete core region of rat or human C5a, and the small-molecule antagonist PMX53-1. These probes were chemically synthesized through hydrazide-based native chemical ligation of a linear peptide hydrazide with the requisite cyclopeptidic antagonist, both of which were made by solid-phase synthesis. Quasi-racemic X-ray crystallography established that attachment of PMX53-1 did not affect the structure of the core region of C5a. Subsequent C5aR1 activity assays demonstrated the probes can provide valuable insights into the development of C5a antagonists;for example, they exhibited significantly better binding affinity and much improved species cross-reactivity than PMX53-1, supporting the notion that the effect of some epitopes outside the C-terminus of C5a should be taken into consideration when designing better C5a antagonists. Surprisingly, the core region of C5a was found to partially agonize C5aR1, suggesting the presence of more than one agonistic interaction in the binding of C5a to C5aR1. This study exemplifies the value of chemical protein synthesis in developing novel receptor probes for drug discovery research. | Chao Zuo Wei-Wei Shi Xiao-Xu Chen Marie Glatz Bernd Riedl Ingo Flamme Elisabeth Pook Jiawei Wang Ge-Min Fang Donald Bierer Lei Liu | 2019 | Science China Chemistry2019，62，10： | 2 |
| 5 | The value of bone scintigraphy on the determination of the full extent of tumor involvement in jaw bones显示文摘目的将有希望地在在颌骨决定肿瘤参与的最大程度上调查骨头 scintigraphy 的价值并且估计转移的存在。这研究有本地道德的委员会赞同的方法,和所有病人给了写的知情同意。有在颌骨的主要恶性瘤的三十七个连续病人为学习被招募。骨头 scintigraphy 在外科前在所有病人被执行测量多骨的参与的最大程度,它与 histologic 调查结果相比。结果全部身体扫描与多重多骨的转移揭示了一个案例。36 个骨头瘤的切除术标本病理地被分析识别每个肿瘤的类型和尺寸。在骨头 scintigraphy 和病理定义的颌骨的肿瘤参与的长度是 5.62 ± 1.58 厘米, 4.48 ± 1.57 厘米,分别地(P <
0.05 ) 。从移开的标本的肿瘤 negative 边缘病理地根据骨头 scintigraphy 被证实。与是的 histologic 调查结果参考的标准,骨头 scintigraphy 的精确性在在颌骨决定肿瘤参与的最大程度是 100%(36 个病人中的 36 个) 。当完全清除肿瘤房间并且每当可能时,保存功能时,结论骨头 scintigraphy 趋于在决定骨头切除术的适当程度提供特定的指南并且在建立多骨的转移。 | Jiawei Xie Chao Ma Guoming Wang Shuyao Zuo Ningyi Li Muyun Jia | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，1： | 2 |
| 6 | Thermally insulating and fire-retardant bio-mimic structural composites with a negative Poisson's ratio for battery protection显示文摘Battery safety has attracted considerable attention worldwide due to the rapid development of wearable electronics and the steady increase in the production and use of electric vehicles.As battery failures are often associated with mechanical-thermal coupled behaviors,protective shielding materials with excellent mechanical robustness and flame-retardant properties are highly desired to mitigate thermal runaway.However,most of the thermal insulating materials are not strong enough to protect batteries from mechanical abuse,which is one of the most critical scenarios with catastrophic consequences.Here,inspired by wood,we have developed an effective approach to engineer a hierarchical nanocomposite via self-assembly of calcium silicate hydrate and polyvinyl alcohol polymer chains(referred as CSH wood).The versatile protective material CSH wood demonstrates an unprecedented combination of light weight(0.018 g cm-3),high stiffness(204 MPa in the axial direction),negative Poisson's ratio(-0.15),remarkable toughness(6.67×105 J m-3),superior thermal insulation(0.0204 W m-1 K-1 in the radial direction),and excellent fire retardancy(UL94-V0).When applied as a protective cover or a protective layer within battery packages,the tough CSH wood can resist high-impact load and block heat diffusion to block or delay the spread of fire,therefore significantly reducing the risk of property damage or bodily injuries caused by battery explosions.This work provides new pathways for fabricating advanced thermal insulating materials with large scalability and demonstrates great potential for the protection of electronic devices. | Fengyin Du Zuquan Jin Ruizhe Yang Menglong Hao Jiawei Wang Gang Xu Wenqiang Zuo Zifan Geng Hao Pan Tian Li Wei Zhang Wei She | 2023 | Carbon Energy2023，5，12： | 0 |
| 7 | Current state of stem cell research in non-human primates:an overview显示文摘The remarkable similarity between non-human primates(NHPs)and humans establishes them as essential models for understanding human biology and diseases,as well as for developing novel therapeutic strategies,thereby providing more comprehensive reference data for clinical treatment.Pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells provide unprecedented opportunities for cell therapies against intractable diseases and injuries.As continue to harness the potential of these biotechnological therapies,NHPs are increasingly being employed in preclinical trials,serving as a pivotal tool to evaluate the safety and efficacy of these interventions.Here,we review the recent advancements in the fundamental research of stem cells and the progress made in studies involving NHPs. | Junmo Wu Yuxi Shi Shanshan Yang Zengli Tang Zifan Li Zhuoyao Li Jiawei Zuo Weizhi Ji Yuyu Niu | 2023 | Medical Review2023，3，4： | 0 |
| 8 | Visualizing carboxyl-terminal domain of RNA polymerase Ⅱ recruitment by FET fusion protein condensates with DNA curtains显示文摘Many recent references show that living cells can form some membrane-less organelles by liquid–liquid phase separation(LLPS) of biomolecules, like proteins and nucleic acids. LLPS has been confirmed to link with many important biological functions in living cells, and one of the most important functions of biomolecular condensates is in the field of RNA transcription. Many studies confirm that mammalian RNA polymerase Ⅱ(Pol Ⅱ) molecules containing the CTD with different phosphorylation level are purposed to shuttle between initiation condensates and elongation condensates of RNA transcription. Traditional ensemble assays often experience difficulties in quantitively and directly recording the transient recruitment of Pol Ⅱ CTD. Novel single-molecule approach - DNA curtains can be used to directly visualize biomolecular condensates formation and also recruitment of RNA polymerase Ⅱ(Pol Ⅱ) carboxyl-terminal domain(CTD) at the target sites in solution and in real time. This method can offer the potential for new insights into the mechanism of gene transcription. Here, we highlight the detailed protocol of DNA curtains method for studying LLPS. | Linyu Zuo Jiawei Ding Zhi Qi | 2022 | Biophysics Reports2022，8，2： | 0 |
| 9 | Autonomous Vehicles Testing Considering Utility-Based Operable Tasks显示文摘Virtual simulation testing of Autonomous Vehicles(AVs)is gradually being accepted as a mandatory way to test the feasibility of driving strategies for AVs.Mainstream methods focus on improving testing efficiency by extracting critical scenarios from naturalistic driving datasets.However,the criticalities defined in their testing tasks are based on fixed assumptions,the obtained scenarios cannot pose a challenge to AVs with different strategies.To fill this gap,we propose an intelligent testing method based on operable testing tasks.We found that the driving behavior of Surrounding Vehicles(SVs)has a critical impact on AV,which can be used to adjust the testing task difficulty to find more challenging scenarios.To model different driving behaviors,we utilize behavioral utility functions with binary driving strategies.Further,we construct a vehicle interaction model,based on which we theoretically analyze the impact of changing the driving behaviors on the testing task difficulty.Finally,by adjusting SV’s strategies,we can generate more corner cases when testing different AVs in a finite number of simulations. | Jingwei Ge Jiawei Zhang Yi Zhang Danya Yao Zuo Zhang Rui Zhou | 2023 | Tsinghua Science and Technology2023，28，5： | 0 |
| 10 | Directing in-situ self-optimization of single-atom catalysts for improved oxygen evolution显示文摘The demand for clean and sustainable energy has encouraged the production of hydrogen from water electrolyzers.To overcome the obstacle to improving the efficiency of water electrolyzers,it is highly desired to fabricate active electrocatalysts for the sluggish oxygen evolution process.However,there is generally an intrinsic gap between the as-prepared and real electrocatalysts due to structure evolution under the oxidative reaction conditions.Here,we combine in-situ anionic leaching and atomic deposition to realize single-atom catalysts with self-optimized structures.The introduced F ions facilitate structural transformation from Co(OH)xF into CoOOH(F),which generates an amorphous edge surface to provide more anchoring sites for Ir single atoms.Meanwhile,the in-situ anionic leaching of F ions elevates the Co valence state of Ir_(1)/CoOOH(F)more significantly than the counterpart without F ions(Ir_(1)/CoOOH),leading to stronger adsorption of oxygenated intermediates.As revealed by electrochemical measurements,the increased Ir loading together with the favored adsorption of*OH intermediates improve the catalytic activity of Ir_(1)/CoOOH(F).Specifically,Ir_(1)/CoOOH(F)delivered a current density of 10 mA cm-2at an overpotential of 238 mV,being lower than 314 mV for Ir_(1)/CoOOH.The results demonstrated the facility of the in-situ optimization process to optimize catalyst structure for improved performance. | Peiyu Ma Chen Feng Huihuang Chen Jiawei Xue Xinlong Ma Heng Cao Dongdi Wang Ming Zuo Ruyang Wang Xilan Ding Shiming Zhou Zhirong Zhang Jie Zeng Jun Bao | 2023 | Journal of Energy Chemistry2023，，5： | 0 |
| 11 | Chip-integrated metasurface full-Stokes polarimetric imaging sensor显示文摘Polarimetric imaging has a wide range of applications for uncovering features invisible to human eyes and conventional imaging sensors.Chip-integrated,fast,cost-effective,and accurate full-Stokes polarimetric imaging sensors are highly desirable in many applications,which,however,remain elusive due to fundamental material limitations.Here we present a chip-integrated Metasurface-based Full-Stokes Polarimetric Imaging sensor(MetaPolarIm)realized by integrating an ultrathin(~600 nm)metasurface polarization filter array(MPFA)onto a visible imaging sensor with CMOS compatible fabrication processes.The MPFA is featured with broadband dielectric-metal hybrid chiral metasurfaces and double-layer nanograting polarizers.This chip-integrated polarimetric imaging sensor enables single-shot full-Stokes imaging(speed limited by the CMOS imager)with the most compact form factor,records high measurement accuracy,dual-color operation(green and red)and a field of view up to 40 degrees.MetaPolarIm holds great promise to enable transformative applications in autonomous vision,industry inspection,space exploration,medical imaging and diagnosis. | Jiawei Zuo Jing Bai Shinhyuk Choi Ali Basiri Xiahui Chen Chao Wang Yu Yao | 2023 | Light(Science & Applications)2023，12，10： | 0 |
| 12 | Enzymatic preparation of mono-and diacylglycerols:A review显示文摘Monoacylglycerols(MAGs) and diacylglycerols(DAGs) are partial glycerides widely used in food industry. They are safe and non-toxic food emulsifiers, especially for MAGs. MAGs account for approximately 75% of the total emulsifiers in food industry worldwide. DAGs are recognized as functional cooking oils, they can suppress body fat accumulation and postprandial serum triacylglycerols(TAGs) level. The traditional production of MAGs and DAGs is based on the chemical method, which requires high reaction temperature usually up to 200–260 ℃. Such high temperature is not suitable for oil containing heat sensitive polyunsaturated fatty acids. Enzymatic approach has been received increasing attentions. Enzymatic production of partial glycerides to replace chemical processes has been in industry, particularly for DAGs production as the products have been claimed as a functional and nutritional oil. Enzyme technology for the processing of oils and fats has been moved to industry step by step and case by case during the last 20 years. More and more applications are particularly moving into bulky oils and fats processing. At the same time, the cost of enzymes as a commercial product is reducing steadily. This review summarized the recent 15 years advances on the the enzymatic preparation of MAGs and DAGs. The critical process parameters under different reaction routes were presented and emphasized. The reaction media not only increased the homogeneity of the reaction system, but also shifted the reaction equilibrium towards the target product generation, and this part was stated in detail. In addition, the patent evaluation was included, and the application of MAGs and DAGs was covered. | Jiawei Zheng Yudong Liang Jiaxi Li Shuping Lin Qiangyue Zhang Kanghua Zuo Nanjing Zhong Xuebing Xu | 2023 | Grain & Oil Science and Technology2023，6，4： | 0 |
| 13 | Deterministic assembly of single optical cavity formed by gold dimensional DNA origami显示文摘Controllable strong interactions between a nanocavity and a single emitter is important to manipulating optical emission in a nanophotonic system but challenging to achieve.Herein a three-dimensional DNA origami,named as DNA rack(DR)is proposed and demonstrated to deterministically and precisely assemble single emitters within ultra-small plasmonic nanocavities formed by closely coupled gold nanorods(AuNRs).Uniquely,the DR is in a saddle shape,with two tubular grooves that geometrically allow a snug fit and linearly align two AuNRs with a bending angle <10°.It also includes a spacer at the saddle point to maintain the gap between AuNRs as small as 2-3 nm,forming a nanocavity estimated to be 20 nm^(3) and an experimentally measured O factor of 7.3.A DNA docking strand is designed at the spacer to position a single fluorescent emitter at nanometer accuracy within the cavity.Using Cy5 as a model emitter,a -30-fold fluorescence enhancement and a significantly reduced emission lifetime(from 1.6 ns to 670 ps)were experimentally verified,confirming significant emitter-cavity interactions.This DR-templated assembly method is capable of fitting AuNRs of variable length-to-width aspect ratios to form anisotropic nanocavities and deterministically incorporate different single emitters,thus enabling flexible design of both cavity resonance and emission wavelengths to tailor light-matter interactions at nanometer scale. | Zhi Zhao Xiahui Chen Jiawei Zuo Ali Basiri Shinhyuk Choi Yu Yao Yan Liu Chao Wang | 2022 | Nano Research2022，15，2： | 0 |
| 14 | Structural color printing via polymer-assisted photochemical deposition显示文摘Structural color printings have broad applications due to their advantages of long-term sustainability,eco-friendly manufacturing,and ultra-high resolution.However,most of them require costly and time-consuming fabrication processes from nanolithography to vacuum deposition and etching.Here,we demonstrate a new color printing technology based on polymer-assisted photochemical metal deposition(PPD),a room temperature,ambient,and additive manufacturing process without requiring heating,vacuum deposition or etching.The PPD-printed silver films comprise densely aggregated silver nanoparticles filled with a small amount(estimated<20%volume)of polymers,producing a smooth surface(roughness 2.5 nm)even better than vacuum-deposited silver films(roughness 2.8 nm)at~4 nm thickness.Further,the printed composite films have a much larger effective refractive index n(~1.90)and a smaller extinction coefficient k(~0.92)than PVD ones in the visible wavelength range(400 to 800 nm),therefore modulating the surface reflection and the phase accumulation.The capability of PPD in printing both ultra-thin(~5 nm)composite films and highly reflective thicker film greatly benefit the design and construction of multilayered Fabry–Perot(FP)cavity structures to exhibit vivid and saturated colors.We demonstrated programmed printing of complex pictures of different color schemes at a high spatial resolution of~6.5μm by three-dimensionally modulating the top composite film geometries and dielectric spacer thicknesses(75 to 200 nm).Finally,PPD-based color picture printing is demonstrated on a wide range of substrates,including glass,PDMS,and plastic,proving its broad potential in future applications from security labeling to color displays. | Shinhyuk Choi Zhi Zhao Jiawei Zuo Hossain Mansur Resalat Faruque Yu Yao Chao Wang | 2022 | Light(Science & Applications)2022，11，5： | 0 |
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