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| 1 | Overexpression of micro RNA_(40)8 enhances photosynthesis, growth, and seed yield in diverse plants显示文摘The ability of a plant to produce grain, fruit, or forage depends ultimately on photosynthesis. There have been few attempts, however, to study micro RNAs, which are a class of endogenous small RNAs post-transcriptionally programming gene expression, in relation to photosynthetic traits. We focused on miR_(40)8, one of the most conserved plant miRNAs, and overexpressed it in parallel in Arabidopsis, tobacco, and rice. The transgenic plants all exhibited increased copper content in the chloroplast, elevated abundance of plastocyanin,and an induction of photosynthetic genes. By means of gas exchange and optical spectroscopy analyses, we showed that higher expression of miR_(40)8 leads to enhanced photosynthesis through improving efficiency of irradiation utilization and the capacity for carbon dioxide fixation. Consequently, miR_(40)8 hyper-accumulating plants exhibited higher rate of vegetative growth. An enlargement of seed size was also observed in all three species overproducing miR_(40)8. Moreover, we conducted a 2-year-two-location field trial and observed miR_(40)8 overexpression in rice significantly increased yield, which was primarily attributed to an elevation in grain weight. Taken together, these results demonstrate that miR_(40)8 is a positive regulator of photosynthesis and that its genetic engineering is a promising route for enhancing photosynthetic performance and yield in diverse plants. | Jiawei Pan Dahui Huang Zhonglong Guo Zheng Kuang He Zhang Xinyu Xie Zengfeng Ma Shaopei Gao Manuel T.Lerdau Chengcai Chu Lei Li | 2018 | Journal of Integrative Plant Biology2018，60，4： | 8 |
| 2 | Inorganic Colloidal Electrolyte for Highly Robust Zinc‑Ion Batteries显示文摘Zinc-ion batteries(ZIBs)is a promising electrical energy storage candidate due to its eco-friendliness,low cost,and intrinsic safety,but on the cathode the element dissolution and the formation of irreversible products,and on the anode the growth of dendrite as well as irreversible products hinder its practical application.Herein,we propose a new type of the inorganic highly concentrated colloidal electrolytes(HCCE)for ZIBs promoting simultaneous robust protection of both cathode/anode leading to an effective suppression of element dissolution,dendrite,and irreversible products growth.The new HCCE has high Zn^(2+)ion transference number(0.64)endowed by the limitation of SO4^(2−),the competitive ion conductivity(1.1×10^(–2) S cm^(−1))and Zn2+ion diffusion enabled by the uniform pore distribution(3.6 nm)and the limited free water.The Zn/HCCE/α-MnO2 cells exhibit high durability under both high and low current densities,which is almost 100%capacity retention at 200 mA g^(−1) after 400 cycles(290 mAh g^(−1))and 89%capacity retention under 500 mA g^(−1) after 1000 cycles(212 mAh g^(−1)).Considering material sustainability and batteries’high performances,the colloidal electrolyte may provide a feasible substitute beyond the liquid and all-solid-state electrolyte of ZIBs. | Jiawei Gao Xuesong Xie Shuquan Liang Bingan Lu Jiang Zhou | 2021 | Nano-Micro Letters2021，13，4： | 6 |
| 3 | Tianwen-1 MINPA observations in the solar wind显示文摘The Mars Ion and Neutral Particle Analyzer(MINPA)is one of the three scientific instruments onboard the Tianwen-1 orbiter to investigate the Martian space environment.During Tianwen-1’s transfer orbit to Mars,the MINPA was switched on to measure the solar wind ions.Here,we present the first results of the MINPA observations in the solar wind.During cruise,nearly half of the MINPA ion field-of-view(FOV)was blocked by the lander capsule;thus only the solar-wind ions with azimuthal speeds pointing towards the unblocked FOV sectors could be detected.We perform a detailed comparison of the MINPA’s solar wind observations with data from Earth-based missions when MINPA reached its count-rate peak,finding a general consistency of the ion moments between them.The blocking effect due to the lander is evaluated quantitatively under varying solar-wind velocity conditions.Despite the blocking effect,the MINPA’s solar wind measurements during the transfer orbit suggest a good performance. | AiBing Zhang LingGao Kong WenYa Li Lei Li BinBin Tang ZhaoJin Rong Yong Wei JiJie Ma YiTeng Zhang LiangHai Xie YuXian Wang JianSen He Bin Liu WenJing Wang Bin Su JiaWei Li Xu Tan Fang Wang TaiFeng Jin FuHao Qiao Peter Wurz Yan Zhu YunFei Bai YiRen Li XinBo Zhu YueQiang Sun YongLiao Zou Chi Wang | 2022 | Earth and Planetary Physics2022，6，1： | 5 |
| 4 | Stereotactic body radiation therapy versus radiofrequency ablation in patients with small hepatocellular carcinoma:a systematic review and meta-analysis显示文摘Background:This study aimed to compare the clinical outcomes and toxicity between small hepatocellular carcinoma(HCC)patients treated with stereotactic body radiation therapy(SBRT)and those treated with radiofrequency ablation(RFA).Methods:We searched databases for relevant clinical studies.The primary outcomes of interest were overall survival(OS)at 1 and 2 years,freedom from local progression(FFLP)rate at 2 years,and complications.Results:Five cohorts from 5 retrospective studies and 4,814 patients with HCC were included.Pooled OS at 2 years was significantly lower for SBRT than for RFA[odds ratio(OR):0.63;95%confidence interval(CI):0.51-0.79;P<0.0001],but the pooled FFLP rate at 2 years was higher for SBRT than for RFA(OR:1.66;95%CI:1.05-2.61;P=0.03).In addition,there was no significant difference in the local and liver toxicities of the two treatments.The contradictory conclusion between the OS and FFLP outcome may be attributed to the difference in radiological dose and location,but there were no uniform criteria to illustrate the radiological dose and location in the included studies.Conclusions:SBRT had a higher local control ratio but poorer prognosis than RFA in patients with small HCC.The local toxicity was comparable in both treatments.Further trials should be designed with uniform standards for SBRT and RFA treatments. | Jiawei Hong Linping Cao Haiyang Xie Yuanxing Liu Jun Yu Shusen Zheng | 2021 | Hepatobiliary Surgery and Nutrition2021，10，5： | 5 |
| 5 | Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells显示文摘Surgery is essential for controlling the symptoms and complications of stage IV breast cancer.However,locoregional treatment of primary tumors often results in distant progression,including lung metastasis,the most common type of visceral metastasis.As a minimally invasive thermal therapy,microwave ablation(MWA)has been attempted in the treatment of breast cancer,but the innate immune response after MWA has not yet been reported.Using two murine models of stage IV breast cancer,we found that MWA of primary breast cancer inhibited the progression of lung metastasis and improved survival.NK cells were activated after MWA of the primary tumor and exhibited enhanced cytotoxic functions,and the cytotoxic pathways of NK cells were activated.Depletion experiments showed that NK cells but not CD4+or CD8+T cells played a pivotal role in prolonging survival.Then,we found that compared with surgery or control treatment,MWA of the primary tumor induced completely different NK-cell-related cytokine profiles.Macrophages were activated after MWA of the primary tumor and produced IL-15 that activated NK cells to inhibit the progression of metastasis.In addition,MWA of human breast cancer stimulated an autologous NK-cell response.These results demonstrate that MWA of the primary tumor in metastatic breast cancer inhibits metastatic progression via the macrophage/IL-15/NK-cell axis.MWA of the primary tumor may be a promising treatment strategy for de novo stage IV breast cancer,although further substantiation is essential for clinical testing. | Muxin Yu Hong Pan Nan Che Li Li Cong Wang Yue Wang Ge Ma Mengjia Qian Jiawei Liu Mingjie Zheng Hui Xie Lijun Ling Yi Zhao Xiaoxiang Guan Qiang Ding Wenbin Zhou Shui Wang | 2021 | Cellular & Molecular Immunology2021，18，9： | 5 |
| 6 | Catalytic Cracking of C4 Olefins over P-Modified HZSM-5 Zeolite显示文摘 | ZHAO Guoliang TENG Jiawei JIN Wenqing YANG Weimin XIE Zaiku CHEN Qingling | 2004 | 催化学报2004，25，1： | 3 |
| 7 | Integrated bioinformatics identifies the dysregulation induced by aberrant gene methylation in colorectal carcinoma显示文摘Colorectal carcinoma(CRC)is one of the most common cancers,and is associated with a poor dlinical outcome.The key genes and potential prognostic markers in colorectal carcinoma remain to be identfed and explored for clinical application.DNA expression/methyl-ation profles were downloaded from the Gene Expression Omnibus(GEO)database to identify differentially expressed/methylated genes(DEGs and DEMs).A total of 255 genes and 372 genes were identified as being up-regulated and down-regulated,respectively,in GSE113513,GSE81558,and GSE89076.There were a total of 3350 hypermethylated genes and 443 hypomethylated genes identifed in GSE 48684.Twenty genes were found to be hypermethylated as well as down-regulated,and a functional enrichment analysis revealed that these genes were mainly involved in cancer-related pathways.Among these 20 genes,GPM6A,HAND2 and C2orf40 were related to poor outcomes in cancer patients based on a survival analysis.Concurrent decreases of GPM6A,HAND2 and C2orf40 protein expression were observed in highly-dif ferentiated colorectal carcinoma tissues,and higher expression levels were found in undifferentiated or minimally-differentiated colorectal carcinoma tissues.In conclusion,20 genes were found to be downregulated and hypermethylated in CRC,among which GPM6A,HAND2 and C2orf40 were explored for their potential prognostic value. | Zhenyu Ye Yecheng Li Jiaming Xie Zhenyu Feng Xiaodong Yang Yong Wu Yuwei Pu Jiawei Gao Xiangrong Xu Zhaobi Zhu Wei Li Wei Chen Chungen Xing | 2021 | Genes & Diseases2021，8，4： | 2 |
| 8 | The value of bone scintigraphy on the determination of the full extent of tumor involvement in jaw bones显示文摘目的将有希望地在在颌骨决定肿瘤参与的最大程度上调查骨头 scintigraphy 的价值并且估计转移的存在。这研究有本地道德的委员会赞同的方法,和所有病人给了写的知情同意。有在颌骨的主要恶性瘤的三十七个连续病人为学习被招募。骨头 scintigraphy 在外科前在所有病人被执行测量多骨的参与的最大程度,它与 histologic 调查结果相比。结果全部身体扫描与多重多骨的转移揭示了一个案例。36 个骨头瘤的切除术标本病理地被分析识别每个肿瘤的类型和尺寸。在骨头 scintigraphy 和病理定义的颌骨的肿瘤参与的长度是 5.62 ± 1.58 厘米, 4.48 ± 1.57 厘米,分别地(P <
0.05 ) 。从移开的标本的肿瘤 negative 边缘病理地根据骨头 scintigraphy 被证实。与是的 histologic 调查结果参考的标准,骨头 scintigraphy 的精确性在在颌骨决定肿瘤参与的最大程度是 100%(36 个病人中的 36 个) 。当完全清除肿瘤房间并且每当可能时,保存功能时,结论骨头 scintigraphy 趋于在决定骨头切除术的适当程度提供特定的指南并且在建立多骨的转移。 | Jiawei Xie Chao Ma Guoming Wang Shuyao Zuo Ningyi Li Muyun Jia | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，1： | 2 |
| 9 | Revealing the critical effect of solid electrolyte interphase on the deposition and detriment of Co(Ⅱ) ions to graphite anode显示文摘'Dissolution,migration,and deposition'of transition metal ions (TMIs) result in capacity degradation of lithium-ion batteries (LIBs).Understanding such detrimental mechanism of TMIs is critical to the development of LIBs with long cycle life.In most previous works,TMIs were directly introduced into the electrolyte to investigate such a detrimental mechanism.In these cases,the TMIs are deposited directly on the fresh anode surface.However,in the practical battery system,the TMIs are deposited on the anode covered with solid electrolyte interphase (SEI) film.Whether the pre-presence of SEI film on anode surface influences the deposition and detriment of TMIs is unclear.In this work,the deposition of Co element on graphite anode with and without SEI film were systematically studied.The results clearly show that,in comparison with that of fresh graphite (SEI-free),the presence of SEI film aggravates the deposition of Co ions due to the Li^(+)–Co^(2+) ion exchange between the SEI and Co^(2+)-containing electrolyte without the driving of the electric field,leading to faster capacity fading of graphite anode.Therefore,how to regulate electrolytes and film-forming additives to design the components of SEI and prevent its exchange with TMIs,is a crucial way to inhibit the deposition and detriment of TMIs on graphite anode. | Qiming Xie Jiawei Chen Lidan Xing Xianggui Zhou Zekai Ma Binhong Wu Yilong Lin Hebing Zhou Weishan Li | 2022 | Journal of Energy Chemistry2022，31，6： | 2 |
| 10 | ESTIMATING MULTI-COUNTRY PROSPERITY INDEX: A TWO-DIMENSIONAL SINGULAR SPECTRUM ANALYSIS APPROACH显示文摘 | ZHANG Jiawei HASSANI Hossein XIE Haibin ZHANG Xun (Corresponding author) | 2014 | Journal of Systems Science & Complexity2014，27，1： | 2 |
| 11 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 12 | Effect of Phos-phorus on HZSM-5 Catalyst for C4-Olefin Cracking Reactions to Produce Propylene 显示文摘 | Zhao Guoliang Teng Jiawei Xie Zaiku | 2007 | JCatal2007，248，1： | 1 |
| 13 | A generic framework for geotechnical subsurface modeling with machine learning显示文摘This study introduces a generic framework for geotechnical subsurface modeling, which accounts for spatial autocorrelation with local mapping machine learning(ML) methods. Instead of using XY coordinate fields directly as model input, a series of autocorrelated geotechnical distance fields(GDFs) is designed to enable the ML models to infer the spatial relationship between the sampled locations and unknown locations. The whole framework using GDF with ML methods is named GDF-ML. This framework is purely data-driven which avoids the tedious work in the scale of fluctuations(SOFs)estimating and data detrending in the conventional spatial interpolation methods. Six local mapping ML methods(extra trees(ETs), gradient boosting(GB), extreme gradient boosting(XGBoost), random forest(RF), general regression neural network(GRNN) and k-nearest neighbors(KNN)) are compared in the GDF-ML framework. The results show that the GDFs are better than the conventional XY coordinate fields based ML methods in both accuracy and spatial continuity. GDF-ML is flexible which can be applied to high-dimensional, multi-variable and incomplete datasets. Among these six methods, GDF with ET method(GDF-ET) clearly shows the best accuracy and best spatial continuity. The proposed GDF-ET method can provide a fast and accurate interpretation of the soil property profile. Sensitivity analysis shows that this method is applicable to very small training dataset size. The associated statistical uncertainty can also be quantified so that the reliability of the subsurface modeling results can be estimated objectively and explicitly. The uncertainty results clearly show that the prediction becomes more accurate when more sampled data are available. | Jiawei Xie Jinsong Huang Cheng Zeng Shan Huang Glen J.Burton | 2022 | Journal of Rock Mechanics and Geotechnical Engineering2022，14，5： | 1 |
| 14 | Does amifostine have ra- dioprotective effects on salivary glands in high-dose radioactive io- dine-treated differentiated thyroid cancer显示文摘 | Chao Ma Jiawei Xie Zhongxin Jiang | 2010 | Eur J Nucl Med Mol Imaging2010，37，： | 1 |
| 15 | Kinetic study of electrochemically produced hydrogen bubbles on Pt electrodes with tailored geometries显示文摘Understanding bubbles evolution kinetics on electrodes with varied geometries is of fundamental importance for advanced electrodes design in gas evolution reaction.In this work,the evolution kinetics of electro-generated hydrogen bubbles are recorded in situ on three(i.e.smooth,nanoporous,and nanoarray)Pt electrodes to identify the geometry dependence.The bubble radius shows a time-dependent growth kinetic,which is tightly-connected to the electrode geometry.Among the three electrodes,the smooth one shows a typical time coefficient of 0.5,in consistence with reported values;the nanoporous one shows a time coefficient of 0.47,less than the classic one(0.5);while the nanoarray one exhibits fastest bubble growth kinetics with a time coefficient higher than 0.5(0.54).Moreover,the nanoarray electrode has the smallest bubble detachment size and the largest growth coefficient(23.3)of all three electrodes.Based on the experimental results,a growth model combined direct bottom-injection with micro-convection is proposed to illustrate the surface geometry dependent coefficients,i.e.,the relationship between geometry and bubble evolution kinetics.The direct injection of generated gas molecules from the bottom of bubbles at the three phase boundaries are believed the key to tailor the bubble wetting states and thus determine the bubble evolution kinetics. | Jingshan Qin Tianhui Xie Daojin Zhou Liang Luo Zhengyi Zhang Zhicheng Shang Jiawei Li Lagnamayee Mohapatra Jinwen Yu Haijun Xu Xiaoming Sun | 2021 | Nano Research2021，14，7： | 1 |
| 16 | Effect of phosphorus on HZSM-5 catalyst for C4-olefin cracking reactions to produce propylene显示文摘 | Zhao Guoliang Teng Jiawei Xie Zaiku | 2007 | Journal of Catalysis2007，248，： | 1 |
| 17 | Wetting behavior of ionic liquid on mesoporous titanium dioxide surface by atomic force microscopy显示文摘 | An Rong Zhu Yudan Wu Nanhua Xie Wenlong Lu Jiawei Feng Xin Lu Xiaohua | 2013 | ACS Applied Materials & Interfaces2013，5，： | 1 |
| 18 | Effect of phosphorus on HZSM-5 catalyst for C4-olefin cracking reactions to produce propylene 显示文摘 | Zhao Guoliang Teng Jiawei Xie Zaiku | 2007 | Journal of Catalysis2007，248，1： | 1 |
| 19 | Transplantable neural progenitor populations derived from rhesus monkey embryonic stem cells显示文摘 | Li Tianqing Zheng Jiawei Xie Yunhua | 2005 | Stem Cells2005，23，9： | 1 |
| 20 | Effect of phosphorus on HZSM-5 catalyst for C 4 -olefin cracking reactions to produce propylene显示文摘 | Guoliang Zhao Jiawei Teng Zaiku Xie Wenqing Jin Weimin Yang Qingling Chen Yi Tang | 2007 | Journal of Catalysis2007，，1： | 1 |
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