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| 1 | Effects of sediment dredging on water quality and zooplankton community structure in a shallow of eutrophic lake显示文摘Effects of suction dredging on water quality and zooplankton community structure in a shallow of eutrophic lake,were evaluated.The results showed that a decreasing trend for levels of phosphorus,organic matter,total suspended solids,Chlorophyll a and Secchi transparency in the water column was found,while levels of water depth,electrical conductivity,total dissolved solids and NO 3--N concentration increased markedly post-dredging.The effects of dredging on dissolved oxygen,pH value and temperature were almost negligible.The zooplankton community structure responded rapidly to the environmental changes caused mainly by dredging.As a result,the abundance of rotifers decreased,while the density of zooplanktonic crustaceans increased markedly.The representative taxa were Brachionus angularis,B.budapestinensis,B.diversicornis,Synchaeta spp.and Neodiaptomus schmackeri.A distinct relationship between zooplankton taxa composition and their environment,unraveled by a redundancy analysis,indicating that the measured environment contributed to the variations in the zooplankton community structure to some extent.The first four synthetic environmental variables explained 51.7% of the taxonomic structure.Therefore,with the reduction of internal nutrient load and a shift in dominance by less eutrophic species,it inferred that dredging might be one of effective measures for environmental improvements of such lakes. | Shiyang Zhang Qiaohong Zhou Dong Xu Jidong Lin Shuiping Cheng Zhenbin Wu | 2010 | Journal of Environmental Sciences2010，22，2： | 41 |
| 2 | 3-year Treatment of Tenofovir Alafenamide vs.Tenofovir Disoproxil Fumarate for Chronic HBV Infection in China显示文摘Background and Aims:Tenofovir alafenamide(TAF)has similar efficacy to tenofovir disoproxil fumarate(TDF)but with improved renal and bone safety in chronic hepatitis B patients studied outside of China.We report 3-year results from two phase 3 studies with TAF in China(Clinicaltrials.gov:NCT02836249 and NCT02836236).Methods:Chinese hepatitis B e antigen(HBeAg)-positive and-negative chronic hepatitis B patients with viremia and elevated alanine aminotransferase were randomized 2:1 to TAF or TDF treatment groups and treated in a double-blind fashion for 144 weeks(3 years).Efficacy responses were assessed by individual study while safety was assessed by a pooled analysis.Results:Of the 334 patients(180 HBeAg-positive and 154 HBeAg-negative)randomized and treated,baseline characteristics were similar between groups.The overall mean age was 38 years and 73%were male.The mean HBV DNA was 6.4 log10 IU/mL.The median alanine aminotransferase was 88 U/L,and 37%had a history of antiviral use.At week 144,the proportion with HBV DNA<29 IU/mL was similar among the two groups,with TAF at 83%vs.TDF at 79%,and TAF at 93%vs.TDF at 92%for the HBeAg-positive and-negative patients,respectively.In each study,higher proportions of TAF than TDF patients showed normalized alanine aminotransferase(via the American Association for the Study of Liver Diseases and the China criteria)and showed loss of HBsAg;meanwhile,the HBeAg seroconversion rates were similar.Treatment was well-tolerated among the TAF patients,who showed a smaller median decline in creatinine clearance(−0.4 vs.−3.2 mL/min;p=0.014)and less percentage change in bone mineral density vs.TDF at hip(−0.95%vs.−1.93%)and spine(+0.35%vs.−1.40%).Conclusions:In chronic hepatitis B patients from China,TAF treatment provided efficacy similar to TDF but with better renal and bone safety at 3 years. | Jinlin Hou Qin Ning Zhongping Duan You Chen Qing Xie Fu-Sheng Wang Lunli Zhang Shanming Wu Hong Tang Jun Li Feng Lin Yongfeng Yang Guozhong Gong John FFlaherty Anuj Gaggar Shuyuan Mo Cong Cheng Gregory Camus Chengwei Chen Yan Huang Jidong Jia Mingxiang Zhang GS-US-320-0110 and GS-US-320-0108 China Investigators | 2021 | Journal of Clinical and Translational Hepatology2021，9，3： | 7 |
| 3 | Inorganic nitrate alleviates the senescence-related decline in liver function显示文摘Senescence-related decline in liver function is a common complication in the elderly that can lead to impaired health in older individuals.Dietary nitrate supplements have physiological and therapeutic effects on organ function by nitrate(NO_3^-)-nitrite(NO_2^-)-nitric oxide(NO)pathway.However,the role of dietary nitrate on the senescence-related decline in liver function is unclear.The findings of the present study showed that nitrate levels in the serum and liver decreased,whereas the levels of alanine aminotransferase(ALT)and aspartate aminotransferase(AST)in serum increased in ageing mice.Consistently,cell senescence,decreased glycogen levels and increased lipid deposition were found in the liver of aged mice,both glucokinase(GCK)and phosphoenolpyruvate carboxykinase(PCK)were down-regulated(n=10).Daily nitrate intake(0.5 mmol L^(-1))restored nitrate levels,decreased ALT and AST levels,and prevented cell senescence and structural and glucose and lipid metabolism degeneration in liver tissue both in D-galactose(D-gal)-induced ageing mice(n=10)and in natural aged mice(n=10).In conclusion,the present study demonstrated that the reduction of nitrate levels was correlated with liver degeneration in ageing individuals and that dietary supplement of nitrate could restore the nitrate levels in serum and the liver and prevent ageing-related liver degeneration. | Haifeng Wang Lei Hu Le Li Xiaoshan Wu Zhipeng Fan Chunmei Zhang Jinsong Wang Jidong Jia Songlin Wang | 2018 | Science China(Life Sciences)2018，61，1： | 5 |
| 4 | Impact of National Centralized Drug Procurement Policy on Antiviral Utilization and Expenditure for Hepatitis B in China显示文摘Background and Aims:The National Centralized Drug Procurement(NCDP)policy was launched in China's Mainland in April 2019,with entecavir(ETV)and tenofovir disoproxil fumarate(TDF)being included in the procurement list.We conducted the current study to investigate the impact of the NCDP policy on the utilization and expenditures of antiviral therapy for chronic hepatitis B(CHB)in China.Methods:Procurement records,including monthly purchase volume,expenditure,and price of nucleos(t)ide analogs(NAs),were derived from the National Healthcare Security Administration from April 2018 to March 2021.The changes in volumes and expenditures of the first-line NAs and bid-winning products were calculated.The effects of price,volume,and structure related to drug expenditure were calculated by the Addis and Magrini(AM)Index System Analysis.Results:The purchase volume of NAs significantly increased from 134.3 to 318.3 million DDDs,whereas the expenditure sharply decreased from 1,623.41 to 490.43 million renminbi(RMB)or 241.94 to 73.09 million US dollars(USD).The proportions of firstline NAs rose from 72.51%(ETV:69.00%,TDF:3.51%)to 94.97%(ETV:77.42%,TDF:17.55%).AM analysis showed that the NCDP policy decreased the expenditure of all NAs(S=0.91)but increased that of the first-line NAs in the bidwinning list(S=1.13).Assuming the population size of CHB patients remains stable and a compliance rate of≥75%,the proportion of CHB patients receiving first-line antiviral therapy would increase from 6.36–8.48%to 11.56–15.41%.Conclusions:The implementation of the NCDP policy significantly increased the utilization of first-line NAs for CHB patients at a lower expenditure.The findings provided evidence for optimizing antiviral therapy strategy and allocating medical resources in China. | Xinyu Zhao Min Li Hao Wang Xiaoqian Xu Xiaoning Wu Yameng Sun Canjian Ning Bingqiong Wang Shuyan Chen Hong You Jidong Jia Yuanyuan Kong | 2022 | Journal of Clinical and Translational Hepatology2022，10，3： | 4 |
| 5 | Disaster Risk Science:A Geographical Perspective and a Research Framework显示文摘In this article,we recall the United Nations’30-year journey in disaster risk reduction strategy and framework,review the latest progress and key scientific and technological questions related to the United Nations disaster risk reduction initiatives,and summarize the framework and contents of disaster risk science research.The object of disaster risk science research is the'disaster system'consisting of hazard,the geographical environment,and exposed units,with features of regionality,interconnectedness,coupling,and complexity.Environmental stability,hazard threat,and socioeconomic vulnerability together determine the way that disasters are formed,establish the spatial extent of disaster impact,and generate the scale of losses.In the formation of a disaster,a conducive environment is the prerequisite,a hazard is the necessary condition,and socioeconomic exposure is the sufficient condition.The geographical environment affects local hazard intensity and therefore can change the pattern of loss distribution.Regional multi-hazard,disaster chain,and disaster compound could induce complex impacts,amplifying or attenuating hazard intensity and changing the scope of affected areas.In the light of research progress,particularly in the context of China,we propose a threelayer disaster risk science disciplinary structure,which contains three pillars(disaster science,disaster technology,and disaster governance),nine core areas,and 27 research fields.Based on these elements,we discuss the frontiers in disaster risk science research. | Peijun Shi Tao Ye Ying Wang Tao Zhou Wei Xu Juan Du Jing'ai Wang Ning Li Chongfu Huang Lianyou Liu Bo Chen Yun Su Weihua Fang Ming Wang Xiaobin Hu Jidong Wu Chunyang He Qiang Zhang Qian Ye Carlo Jaeger Norio Okada | 2020 | International Journal of Disaster Risk Science2020，11，4： | 4 |
| 6 | Evaluation of menopausal status among breast cancer patients with chemotherapy-induced amenorrhea显示文摘Objective: In patients with chemotherapy-induced amenorrhea(CIA), the menopausal status is ambiguous and difficult to evaluate. This study aimed to establish a discriminative model to predict and classify the menopausal status of breast cancer patients with CIA.Methods: This is a single center hospital-based study from 2013 to 2016. The menopausal age distribution and accumulated incidence rate of CIA are described. Multivariate models were adjusted for established and potential confounding factors including age, serum concentration of estradiol(E2) and follicle-stimulating hormone(FSH),feeding, pregnancy, parity, abortions, and body mass index(BMI). The odds ratio(OR) and 95% confidence interval(95% CI) of different risk factors were estimated.Results: A total of 1,796 breast cancer patients were included in this study, among whom, 1,175(65.42%) were premenopausal patients and 621(34.58%) were post-menopause patients. Five hundred and fifty patients were included in CIA analysis, and a cumulative CIA rate of 81.64% was found in them. Age(OR: 1.856, 95% CI:1.732-1.990), serum concentration of E2(OR: 0.976, 95% CI: 0.972-0.980) and FSH(OR: 1.060, 95% CI:1.053-1.066), and menarche age(OR: 1.074, 95% CI: 1.009-1.144) were found to be associated with the patients' menopausal status. According to multivariate analysis, the discriminative model to predict the menopausal status is Logit(P)=-28.396+0.536 Age-0.014 E2+0.031 FSH. The sensitivities for this model were higher than 85%, and its specificities were higher than 89%.Conclusions: The discriminative model obtained from this study for predicting menstrual state is important for premenopausal patients with CIA. This model has high specificity and sensitivity and should be prudently used. | Bailin Zhang Jinqi Wu Rongshou Zheng Qian Zhang Margaret Zhuoer Wang Jun Qi Haijing Liu Yipeng Wang Yang Guo Feng Chen Jing Wang Wenyue Lyu Jidong Gao Yi Fang Wanqing Chen Xiang Wang | 2018 | Chinese Journal of Cancer Research2018，30，4： | 2 |
| 7 | Three-Dimensional Conformal Radiotherapy for Rectal Cancer and the Changes in Cancer Multi-biomarkers显示文摘OBJECTIVE To investigate the clinical efficacy of three-dimensional conformal radiotherapy(3D-CRT)for local y advanced or postoperatively relapsed rectal cancer,and to examine the changes in cancer multi-biomarkers. METHODS Sixty patients with locally advanced or postoperatively relapsed rectal cancer were randomly divided into two groups after 40 Gy external radiation,namely a late-course 3D-CRT group and a conventional radiotherapy group that served as the control.There were 30 patients in each group.For patients in the 3D-CRT group,multi-biomarkers were measured before and after radiotherapy and after relapse. RESULTS Response rates in the 3D-CRT and the control groups were 86.7%(26/30)and 70%(21/30)respectively,without a significant difference (P>0.05).The 1-,2-and 3-year survival rates were 80%,53.3%and 36.7% in the 3D-CRT group;in the control group the rates were 56.7%,40%and 13.3%respectively,with a significant difference(P=0.0213).CEA,CA19-9, CA242 and FER decreased after radiotherapy in the 3D-CRT group,P<0.01, indicating a significant difference.The values after relapse were higher than those without relapse,P<0.01,indicating a significant difference. CONCLUSION Conventional radiotherapy with a 3D-CRT boost gives better therapeutic effect to patients with locally advanced or postoperatively local y relapsed rectal cancer.A multi-biomarker protein chip diagnosis system can be utilized as an effective tool to determine the therapeutic effect and prognosis. | Rui Wei Yangde Zhang Jiantai He Liangfang Shen Jidong Hong Haijun Wu | 2007 | Chinese Journal of Clinical Oncology2007，4，6： | 2 |
| 8 | Multi-agent Simulation for Strategic Bidding in Electricity Markets Using Reinforcement Learning显示文摘In this paper,a theoretical framework of Multiagent Simulation(MAS)is proposed for strategic bidding in electricity markets using reinforcement learning,which consists of two parts:one is a MAS system used to simulate the competitive bidding of the actual electricity market;the other is an adaptive learning strategy bidding system used to provide agents with more intelligent bidding strategies.An ExperienceWeighted Attraction(EWA)reinforcement learning algorithm(RLA)is applied to the MAS model and a new MAS method is presented for strategic bidding in electricity markets using a new Improved EWA(IEWA).From both qualitative and quantitative perspectives,it is compared with three other MAS methods using the Roth-Erev(RE),Q-learning and EWA.The results show that the performance of the MAS method using IEWA is proved to be better than the others.The four MAS models using four RLAs are built for strategic bidding in electricity markets.Through running the four MAS models,the rationality and correctness of the four MAS methods are verified for strategic bidding in electricity markets using reinforcement learning. | Jidong Wang Jiahui Wu Xiangyu Kong | 2023 | CSEE Journal of Power and Energy Systems2023，9，3： | 1 |
| 9 | Agent-based dynamic simulation of an electricity market with multilateral bidding显示文摘The electricity market is a complex system in which participants interact and compete with each other,which makes description of them with mathematical models difficult.To solve these difficulties,computer simulation has become one of the main methods for studying electricity market problems.How to establish a reasonable electricity market has always been a major research issue in the electric power industry,for which a key point is the bidding mechanism.Agent-based modeling and a simulation(ABMS)method are used in this paper to study the imperfect competitive electricity market.An agent-based simulation method of multilateral bargaining game theory in the dynamics of the power bidding market is presented,and a multi-agent power market bidding dynamics simulation model based on game theory is established.The dynamic bidding game behavior among the government,power grid companies,power plant companies,and consumer parties is simulated in the market,and the simulation method is realized by Anylogic software.Finally,an agent-based four-party competitive dynamic game simulation in the electricity market is implemented,which provides a theoretical reference for further understanding resource optimization problems in the electricity market. | Jiahui Wu Jidong Wang Yuanyuan Yan | 2019 | International Journal of Modeling, Simulation, and Scientific Computing2019，10，3： | 1 |
| 10 | Model based verification of dynamically evolvable service oriented systems显示文摘Dynamic evolution is highly desirable for service oriented systems in open environments. For the evolution to be trusted, it is crucial to keep the process consistent with the specification. In this paper, we study two kinds of evolution scenarios and propose a novel verification approach based on hierarchical timed automata to model check the underlying consistency with the specification. It examines the procedures before, during and after the evolution process, respectively and can support the direct modeling of temporal aspects, as well as the hierarchical decomposition of software structures. Probabilities are introduced to model the uncertainty characterized in open environments and thus can support the verification of parameter-level evolution. We present a flattening algorithm to facilitate automated verification using the mainstream timed automata based model checker –UPPAAL(integrated with UPPAAL-SMC). We also provide a motivating example with performance evaluation that complements the discussion and demonstrates the feasibility of our approach. | Yu ZHOU Jidong GE Pengcheng ZHANG Weigang WU | 2016 | Science China(Information Sciences)2016，59，3： | 1 |
| 11 | Interface engineering of Zn meal anodes using electrochemically inert Al_(2)O_(3)protective nanocoatings显示文摘Aqueous rechargeable Zn-ion batteries are regarded as a promising alternative to lithium-ion batteries owing to their high energy density,low cost,and high safety.However,their commercialization is severely restricted by the Zn dendrite formation and side reactions.Herein,we propose that these issues can be minimized by modifying the interfacial properties through introducing electrochemically inert Al_(2)O_(3)nanocoatings on Zn meal anodes(Al_(2)O_(3)@Zn).The Al_(2)O_(3)nanocoatings can effectively suppress both the dendrite growth and side reactions.As a result,the Al_(2)O_(3)@Zn symmetric cells show excellent electrochemical performance with a long lifespan of more than 4,000 h at 1 mA·cm^(−2)and 1 mAh·cm^(−2).Meanwhile,the assembled Al_(2)O_(3)@Zn//V_(2)O_(5)full cells can deliver a high capacity(236.2 mAh·g^(−1))and long lifespan with a capacity retention of 76.11%after 1,000 cycles at 4 A·g^(−1). | Rui Wang Qiongfei Wu Minjie Wu Jiaxian Zheng Jian Cui Qi Kang Zhengbing Qi JiDong Ma Zhoucheng Wang Hanfeng Liang | 2022 | Nano Research2022，15，8： | 1 |
| 12 | Epitaxial growth of large area ZrS_(2)2D semiconductor films on sapphire for optoelectronics显示文摘Recently,group-IVB semiconducting transition metal dichalcogenides(TMDs)of ZrS_(2) have attracted significant research interest due to its layered nature,moderate band gap,and extraordinary physical properties.Most device applications require a deposition of high quality large-area uniform ZrS_(2) single crystalline films,which has not yet been achieved.In this work,for the first time,we demonstrate the epitaxial growth of high quality large-area uniform ZrS_(2) films on c-plane sapphire substrates by chemical vapor deposition.An atomically sharp interface is observed due to the supercell matching between ZrS_(2) and sapphire,and their epitaxial relationship is found to be ZrS_(2)(0001)[1010]||Al_(2)O_(3)(0001)[1120].The epitaxial ZrS_(2) film exhibits n-type semiconductor behavior with a room temperature mobility of 2.4 cm^(2)·V^(−1)·s^(−1),and the optical phonon is the dominant scattering mechanism at room temperature or above.Furthermore,the optoelectronic applications of ZrS_(2) films are demonstrated by fabricating photodetector devices.The ZrS_(2) photodetectors exhibit the excellent comprehensive performance,such as a light on/off ratio of 106 and a specific detectivity of 2.6×10^(12) Jones,which are the highest values compared with the photodetectors based on other group-IVB two-dimensional TMDs. | Yan Tian Yong Cheng Jidong Huang Siyu Zhang Hao Dong Gaokai Wang Jingren Chen Jinliang Wu Zhigang Yin Xingwang Zhang | 2022 | Nano Research2022，15，7： | 1 |
| 13 | Study on Performance of Di-(2, 4, 4-trimethylpentyl) phosphinic Acid for Separating Tm in high purity Eu2O3 显示文摘 | Li Jidong Wu Xing Zheng Yongzhang | 2002 | Rare Metals2002，21，： | 1 |
| 14 | Study on performance of Di(2,4,4-trimethylpentyl)phosphinic acid for separating Tm in high purity Eu2O3显示文摘 | Li Jidong Wu Xing Zheng Yongzhang | 2002 | Rare Metals2002，21，7： | 1 |
| 15 | Enhanced patency of venous dacron grafts by endothelial cell sodding显示文摘 | Zhong-Gao Wang MD Guangdi Li MD Jidong Wu MD Wei Du MD Liqun Pu MD Hai Zhang MD Dajie Wang MD Bauer E. Sumpio MD PhD | 1993 | Annals of Vascular Surgery1993，，5： | 1 |
| 16 | The return period analysis of natural disasters with statistical modeling of bivariate joint proba- bility distribution显示文摘 | Li Ning Liu Xueqin Wu Jidong | 2013 | Risk Analysis2013，33，1： | 1 |
| 17 | Rationale and Study Design for Evaluating the Efficacy and Safety of Intracardiac Echocardiography-Guided Minimal-Fluoroscopy Ablation in Patients with Paroxysmal Atrial Fibrillation:A Non-Inferior,Multi-Center,Prospective Randomized Controlled Trial(PAF-ICE Trial)显示文摘The feasibility and safety of intracardiac echocardiography(ICE)-guided catheter ablation for atrial fibrillation(AF)using a minimal/zero-fluoroscopy approach have recently been reported.This approach helps to reduce ionizing radiation exposure and orthopedic complications resulting from using lead aprons.The objectives of this planned prospective,multicenter randomized controlled trial(RCT)(paroxysmal AF(PAF)-ICE trial;ChiCTR2000033624)are to evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF and the impact on occupational hazards among lab staff.Patients will be randomized in a 1:1 ratio to 2 groups:minimal fluoroscopy group(n=216)and traditional approach group(n=216).In the minimal fluoroscopy group,an ICE catheter will be used for geometry/anatomic construction,transseptal puncture,catheter tracking,and effusion monitoring.Pulmonary vein isolation(PVI)will be performed using an open-irrigated radiofrequency SmartTouch Surround Flow or SmartTouch catheter(Biosense Webster,Diamond Bar,California,USA),and confirmed by a multipolar Lasso or PentaRay catheter(Biosense Webster).In the traditional approach group,an ICE catheter will not be used.Transseptal puncture will be performed under fluoroscopic guidance,with all geometries constructed by mapping the catheters.The primary efficacy endpoint is freedom from AF recurrence(without antiarrhythmic medications)at 12months after ablation.Other endpoints include duration of lead apron use,measures of intra-procedural efficiency,and peri-procedural complications.This RCT will evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF,also evaluate the benefits to lab staff(regarding reducing occupational hazards)related to this“minimal/zero-fluoroscopy”and“leadless”mode. | Ruhong Jiang Xingpeng Liu Jidong Zhang Yu Chen Rui Wang Mengzuo Wu Deyong Long Jia Li Haixiong Wang Jie Fan Weizhu Ju Weili Ge Xu Liu Hai Deng Weijian Wang Pingzhen Yang Ding Li Xiaobo Huang Xiongtao Liu Hailong Tao Paul CZei Roderick Tung Xunzhang Wang Chenyang Jiang | 2021 | Cardiology Discovery2021，1，4： | 1 |
| 18 | Impact of Economic Development Levels and Disaster Types on the Short-Term Macroeconomic Consequences of Natural Hazard-Induced Disasters in China显示文摘The relationship between natural hazard-induced disasters and macroeconomic growth has been examined widely on global and national scales, but little research has been focused on the subnational level, especially in China.We examined the impacts of natural hazard-induced disasters on the regional growth in China based on subnational panel data for the period from 1990 to 2016. First, we used the number of people affected and the direct economic losses as the measures of the scale of disasters. Then, we used the direct damages of meteorological disasters and earthquakes as disaster measures separately to examine the impacts of different disaster types. Finally, we performed intraregional effects regressions to observe the spatial heterogeneity within the regions. The results show that the adverse short-term effects of disasters is most pronounced in the central region, while the direct damage of disasters is a positive stimulus of growth in the whole of China.However, this stimulus is observed in a lagged way and is reflected differently—meteorological disasters in central and eastern China and earthquakes in western China are related to regional growth. The results demonstrate that the short-term macroeconomic impacts of these disasters in the three geographical regions of China largely depend on regional economic development levels and the disaster types. | Rumei Tang Jidong Wu Mengqi Ye Wenhui Liu | 2019 | International Journal of Disaster Risk Science2019，10，3： | 1 |
| 19 | Comprehensive assessment of flood risk using the classification and regression tree method显示文摘 | Zhonghui Ji Ning Li Wei Xie Jidong Wu Yang Zhou | 2013 | Stochastic Environmental Research and Risk Assessment2013，，8： | 1 |
| 20 | MORNING GLOW OVER THE CITY显示文摘When Chinese read phrases such as guangmang wanzhang or jinxia wuyunlong,they may associate these descriptions with a beautiful morning glow and become intoxicated by the glorious scenes.In Chinese,countless characters and sentences can describe the natural beauty of the moment when the first glow of morning appears in the sky. | Wang Wei He Bingfu(Photos) Li Jidong(Photos) Wu Hui(Photos) Wu Luping(Photos) Zhang Yonghong(Photos) Zhang Ziliang(Photos) | 2021 | Beijing2021，，1： | 0 |
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