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| 1 | Evaluating ischemic stroke with diffusion tensor imaging显示文摘Objective:In recent years,diffusion tensor imaging (DTI) has emerged as a promising tool to study ischemic stroke. The aim of this study is to evaluate the anisotropic changes of cerebral white matter tracks in patients with ischemic stroke using DTI,and investigate the correlation between corticospinal tract damage and muscle strength in such patients during acute ischemia.Method:9 patients with acute ischemic stroke and 9 healthy subjects were examined with T1 weighted magnetic resonance imaging (MRI),T2 weighted MRI and DTI. Fractional anisotropy (FA) was measured and the three-dimensional fibrous band images of bilateral corticospinal tracts were reconstructed. The muscle strength of the affected hand was assessed by Brunnstorm standard[1],which is an internationally recognized measure of movement in hemiplegic patients.Results:①In the control group,there was no significant difference in FA between the bilateral corticospinal tracts,but FA in different white matter structure of the same side was significantly different (t=3.12,P < 0.05). FA of posterior limb of internal capsule was higher than that of knee and anterior limb of internal capsule,FA of anterior limb of internal capsule was the lowest. while in the patient group,FA of the infarcted sites was significantly lower than the contralateral ones (t=5.570,P < 0.01). ②The ipsilateral corticospinal tract demonstrated continuous interruption and the loss of consistent anatomic structure. The involved severity of corticospinal tract had significant correlation with that of muscle strength of the ipsilateral hand (r=0.83,P < 0.01).Conclusion:This study shows that DTI can be used to investigate ischemic stroke and assess ischemic stroke-induced damage. The damaged severity of corticospinal tracts is correlated with that of muscle strength. | Ziqian Chen Ping Ni Youqiang Ye Hui Xiao Gennian Qian Shangwen Xu Jingliang Wang Xizhang Yang Jinhua Chen Zhenshan Shi Biyun Zhang | 2008 | 福州总医院学报2008，15，3： | 6 |
| 2 | Microwave-assisted synthesis of colorimetric and fluorometric dual-functional hybrid carbon nanodots for Fe^(3+) detection and bioimaging显示文摘Carbon nanodots(CDs) based fluorescent nanoprobes have recently drawn much attention in chemo-/bio-sensing and bioimaging.However,it is still challenging to integrate the colorimetric and fluorometric dual readouts into a single CD.Herein,novel hybrid CDs(HCDs) are prepared by a simple microwave-assisted reaction of citric acid(CA),branched polyethyleneimine(BPEI) and potassium thiocyanate(KSCN).As-prepared HCDs show extraordinary properties,including excitation-dependent emission,satisfactory fluorescence quantum yield(46.8%),excellent biocompatibility and optical stability.Significantly,the fluorescence intensity at 450 nm exhibits linear correlation over the Fe^(3+)concentration from 1 mmol/L to 150 mmol/L with a detection limit(LOD) of 52 nmol/L.Meanwhile,the solution color changes from colorless to orange,and the absorbance at 460 nm increased linearly with Fe^(3+)concentration ranging from 0.02 mmol/L to 5 mmol/L(LOD:3.4 mmol/L).All the evidence illustrates that the HCDs can be conditioned for specific Fe^(3+)sensing with colorimetric and fluorometric dual readouts,which has also been verified with paper-based microchips.The possible mechanism is attributed to the specific interactions between surface functional groups on the HCDs and Fe^(3+).Additionally,the HCDs are successfully applied in sensing Fe^(3+)in wastewater and living cells,demonstrating its potential applications in future environment monitoring and disease diagnosis. | Yupeng Shi Jingjing Liu Yong Zhang Jianfeng Bao Jingliang Cheng Changqing Yi | 2021 | Chinese Chemical Letters2021，32，10： | 1 |
| 3 | The effect of citric acid on the structural properties and cytotoxicity of the pol- yvinyl alcohol/starch films when molding at high temperature显示文摘 | Rui Shi Jingliang | 2008 | Carbo Poly2008，74，： | 1 |
| 4 | Dynamic Target Enclosing Control Scheme for Multi-Agent Systems via a Signed Graph-Based Approach显示文摘Dear Editor,This letter investigates the target enclosing control problem of multi-agent systems.A signed graph-based control strategy is presented,where the agents are steered to enclose the dynamic target from both sides as they move.This is inspired by the phenomenon that signed networks exhibit bipartite clustering if the underlying graph is structurally balanced,so that the agents may naturally enclose the zero point from opposite sides(+and.)if proper controllers are applied.By adopting a distributed observer to estimate the information of dynamic target。 | Weihao Li Kaiyu Qin Mengji Shi Jingliang Shao Boxian Lin | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，2： | 0 |
| 5 | Study design of deep learning based automatic detection of cerebrovascular diseases on medical imaging: a position paper from Chinese Association of Radiologists显示文摘In recent years,with the development of artificial intelligence,especially deep learning technology,researches on automatic detection of cerebrovascular diseases on medical images have made tremendous progress and these models are gradually entering into clinical practice.However,because of the complexity and flexibility of the deep learning algorithms,these researches have great variability on model building,validation process,performance description and results interpretation.The lack of a reliable,consistent,standardized design protocol has,to a certain extent,affected the progress of clinical translation and technology development of computer aided detection systems.After reviewing a large number of literatures and extensive discussion with domestic experts,this position paper put forward recommendations of standardized design on the key steps of deep learning-based automatic image detection models for cerebrovascular diseases.With further research and application expansion,this position paper would continue to be updated and gradually extended to evaluate the generalizability and clinical application efficacy of such tools. | Longjiang Zhang Zhao Shi Min Chen Yingmin Chen Jingliang Cheng Li Fan Nan Hong Wenxiao Jia Guihua Jiang Shenghong Ju Xiaogang Li Xiuli Li Changhong Liang Weihua Liao Shiyuan Liu Zaiming Lu Lin Ma Ke Ren Pengfei Rong Bin Song Gang Sun Rongpin Wang Zhibo Wen Haibo Xu Kai Xu Fuhua Yan Yizhou Yu Yunfei Zha Fandong Zhang Minwen Zheng Zhen Zhou Wenzhen Zhu Guangming Lu Zhengyu Jin on behalf of Chinese Association of Radiologists | 2022 | Intelligent Medicine2022，2，4： | 0 |
| 6 | On the parity-check matrix of generalized concatenated code显示文摘Dear editor,Single-level concatenation using a nonbinary code as outer code and a binary code as inner code is widely used in communication and digital data storage systems to achieve high reliability with reduced decoding complexity[1].Moreover,concatenation can be multilevel,where multiple outer codes are concatenated with multiple inner codes;it is referred as generalized concatenated codes(GCCs).Compared with the single-level concatenated codes,GCCs offer more flexibility for constructing good codes and designing error-control systems with different code rates for various communication environments[2]. | Sha SHI Yang LIU Junzhi YAN Jingliang GAO Yunjiang WANG | 2020 | Science China(Information Sciences)2020，63，4： | 0 |
| 7 | Varroa destructor mite infestations in capped brood cells of honeybee workers affect emergence development and adult foraging ability显示文摘Given recent higher declines in managed Apis mellifera honeybees,which are the most commonly managed bee species around the world(Garibaldi et al.2013),numerous health threats involved in the losses have been received great attention.To date,Varroa destructor mite infestation has become the biggest challenge in commercial beekeeping,which is considered as a thorn stuck in the throat of beekeepers.The Varroa mite threatens bee health by absorbing the fat body and hemolymph of immature and mature bees(Ramsey et al.2019).Varroa mite infestation during the development of worker bees was found to reduce birth weight,influence water content and protein level in hemolymph of newly emerged worker bees,decrease flight performance of drones,change gene expression patterns related to immune system of honeybees,and result in honeybee colony losses(Duay et al.2002;Bowen-Walker and Gunn 2010;Zhang et al.2010;Annoscia et al.2012;Dooremalen et al.2013;Locke 2016).The Varroa mite,as an ectoparasite of the honeybee,prefers living in the sealed brood cells(Bogdanov 2006).Thus,bees are more likely to become hosts of mites in the pupal stage.In this study,we systematically investigated the current impacts of V.destructor infestations on the development from capped larvae to emerged bees. | Heyan YANG Jingliang SHI Chunhua LIAO Weiyu YAN Xiaobo WU | 2021 | Current Zoology2021，67，5： | 0 |
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