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| 1 | Multiresidue determination and potential risks of emerging pesticides in aquatic products from Northeast China by LC-MS/MS显示文摘A simple method for determining 33 pesticides with a wide polarity range(log Kow0.6-4.5) in aquatic products was developed based on LC–MS/MS. The target analytes included three types of widely used pesticides: insecticides, fungicides and herbicides. Based on the optimization of ultrasonic assisted extraction and GPC clean-up procedures, the matrix effect, extraction recoveries and LOD were improved distinctively. LOQ of this method was below 0.5 ng/g for all pesticides, which is superior to values in the literature, and the matrix effect was reduced effectively(-14.7% to 7.5%). The method was successfully applied to investigate the pesticide residue levels of twenty-five samples including seven common kinds of fishes from Northeast China. The results showed that all targeted pesticides were present in the fish samples; however, their levels were low, except for atrazine, linuron,ethoprophos, tetrachlorvinphos, acetochlor and fenthion. Atrazine and linuron caught our attention because the concentrations of atrazine in fish samples from Liaoning province were in the range of 0.5-8 ng/g(w/w) with mean concentration of 2.3 ng/g, which were far above those of other pesticides. The levels of linuron were in the range of 0.6-6 ng/g(mean concentration 2.8 ng/g), which were the highest among all targeted pesticides in the Inner Mongolia. This is the first systematic investigation on the characteristics and levels of these pesticides in aquatic products from northeast China. Considering their toxicity and bioaccumulation, the potential risk of atrazine and linuron from consuming aquatic products should be paid more attention. | Lei Fu Xianbo Lu Jun Tan Longxing Wang Jiping Chen | 2018 | Journal of Environmental Sciences2018，30，1： | 17 |
| 2 | Comparison of clinical effectiveness of acupuncture and a Western drug on allergic rhinitis:study protocol for a randomized controlled trial显示文摘OBJECTIVE: To compare the efficacy of an acupuncture regimen for persistent allergic rhinitis(PER), aimed at improving a patient's mind or Shen in Traditional Chinese Medicine, to that of a second-generation H1-receptor antagonist, cetirizine hydrochloride.METHODS: This multicenter, randomized, controlled clinical trial on PER will be conducted at three institutions in China. The total study period will be 9 weeks. After a 1-week preparatory screening period, 240 eligible participants with PER willbe randomized to receive acupuncture or pharmacotherapy(1∶1) for 4 weeks with a 4-week follow-up. The primary outcome will be changes in7-day average total nasal symptom score. Secondary outcome measures include rhinoconjunctivitis quality of life questionnaire score and total non-nasal symptom score.RESULTS:The presence and seriousness of psychological and emotional impairments should be considered in therapeutic programs for allergic rhinitis.No clinical trial for treating allergic rhinitis via acupuncture regulation of psychological and emotionalactivitieshasbeenreported.CONCLUSION:The findings of the trial will allow us to determine the effects of the mind(Shen)-regulation treatment approach. We will also be able to confirm if the effects of acupuncture are equivalent to those of the conventional drug cetirizine hydrochloride. | Yanping Wang Sheng Chen Peng Wang Cheng Tan Chang Zhang Zhihong Shi Jiping Zhao | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 9 |
| 3 | Presence, dissemination and removal of antibiotic resistant bacteria and antibiotic resistance genes in urban drinking water system: A review显示文摘Antibiotic resistance in aquatic environment has become an important pollution problem worldwide. In recent years, much attention was paid to antibiotic resistance in urban drinking water systems due to its close relationship with the biosafety of drinking water. This review was focused on the mechanisms of antibiotic resistance, as well as the presence, dissemination and removal of antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in the urban drinking water system. First, the presence of ARB and ARGs in the drinking water source was discussed. The variation of concentration of ARGs and ARB during coagulation, sedimentation and filtration process were provided subsequently, in which filtration was proved to be a promising technology to remove ARGs. However, biological activated carbon (BAC) process and drinking water distribution systems (DWDSs) could be incubators which promote the antibiotic resistance, due to the enrichment of ARGs and ARB in the biofilms attached to the active carbon and pipe wall. Besides, as for disinfection process, mechanisms of the inactivation of ARB and the promotion of conjugative transfer of ARGs under chlorine, ozone and UV disinfection were described in detail. Here we provide some theoretical support for future researches which aim at antibiotic resistance controlling in drinking water. | Qiaowen Tan Weiying Li Junpeng Zhang Wei Zhou Jiping Chen Yue Li Jie Ma | 2019 | Frontiers of Environmental Science & Engineering2019，13，3： | 8 |
| 4 | Hexabromocyclododecane and tetrabromobisphenol A in sediments and paddy soils from Liaohe River Basin, China: Levels, distribution and mass inventory显示文摘Hexabromocyclododecane(HBCD) and tetrabromobisphenol A(TBBPA) are two kinds of brominated flame retardants and widely present in the environment and biota. The levels,spatial distributions and mass inventories of HBCD and TBBPA were investigated in sediments and paddy soils from the Liaohe River Basin in northeast China. The concentrations of ΣHBCD and TBBPA were in the range of not detected(nd) to 4.02 ng/g dry weight(dw) and 0.03 to 4.06 ng/g dw, respectively. γ-HBCD was dominated in sediments,while the abundance of α-HBCD was relatively high in paddy soils. The spatial distributions of HBCD and TBBPA in surface sediments and paddy soils indicated that the local point-input was their major source. The significant correlation between total organic carbon(TOC) contents and the HBCD levels suggested that TOC content also exerted an influence on the distribution of HBCD in sediments. Meanwhile, it was found that the irrigation with river water was not the major transportation pathway of HBCD and TBBPA in paddy soils. Based on the study, it was estimated that there were about 1.67 tons HBCD and 2.20 tons TBBPA deposited into sediments of the Liaohe River system every year. The total mass inventories of HBCD and TBBPA in sediments were far higher than that in paddy soils. | Fang Li Jing Jin Dongqin Tan Longxing Wang Ningbo Geng Rong Cao Yuan Gao Jiping Chen | 2016 | Journal of Environmental Sciences2016，28，10： | 7 |
| 5 | Agricultural land use intensity study in Taibus Banner, and its determinants: a case Inner Mongolia, China显示文摘 | Haiguang HAO Xiubin LI Minghong TAN Jiping ZHANG Huiyuan ZHANG | 2015 | Frontiers of Earth Science2015，9，2： | 5 |
| 6 | Theory,controls parameter and application of the packed-bed electroosmotic pump显示文摘Theory and controls parameters affecting the output pressure and flow rate of the packed-bed electroos-motic pump (p-EOP), including zeta potential z, electric in-tensity E, length of the column L, cross-section area of the column A, dielectric constant e and viscosity coefficient h of the liquid being pumped, are discussed concisely. And also, the fabrication and application of the p-EOP are introduced. | CHEN Lingxin, GUAN Yafeng, MA Jiping, SHU Xin & TAN Feng Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116012, China Correspondence should be addressed to Guan Yafeng (e-mail: kfguan@ mail.dlptt.ln.cn) | 2003 | Chinese Science Bulletin2003，48，23： | 3 |
| 7 | Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘 | Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning | 2014 | Chinese Medical Journal2014，，3： | 3 |
| 8 | Awareness intervention for Beijing neurologists regarding secondary prevention of cerebral infarction/transient ischemia Cross-sectional investigation显示文摘BACKGROUND: Stroke prevention guidelines should be made available to neurologists for clinical application to aid in uniformity, timing, preciseness, and acceptance of disease. OBJECTIVE: To investigate the awareness of neurologists in some Beijing hospitals of intervention in secondary prevention of cerebral infarction/transient ischemia. DESIGN: Cross-sectional study. SETTING: Beijing Tiantan Hospital, Beijing Anzhen Hospital, General Hospital of Beijing Military Area, Command of Chinese PLA, Beijing Chuiyangliu Hospital, Beijing 6th Hospital, Beijing Hepingli Hospital, and Beijing Daxing District Hospital. PARTICIPANTS: A total of 28 (associate) chief physicians, 58 attending physicians, and 54 resident physicians who engaged in clinical treatment of cerebrovascular diseases were selected from 8 hospitals in Beijing from March to April 2007. All physicians provided informed consent. METHODS: Self-made closed questionnaires were provided for data collection, consisting of 16 questions that were single choice or multiple choice. Specifically, questions 1-7 focused on awareness of blood pressure regulation in different patients and first choice of decompression drug; questions 8-12 focused on awareness of lipid regulation; and questions 13-16 focused on awareness of anti-blood platelet drugs applied in secondary prevention. The scores ranged from 0-100 points, and each question was worth 6.25 points. The scores positively correlated with the awareness rate. To test leveling real-time, the survey lasted for a maximum of 20 minutes. One questionnaire was independently finished by each subject in the survey. MAIN OUTCOME MEASURES: Awareness intervention among neurologists during secondary prevention of cerebral infarction/transient ischemia and questionnaire scores. RESULTS: 140 subjects were included in the final analysis. ① The awareness rate among neurologists for intervention during secondary prevention of cerebral infarction/transient ischemia ranged from 0.7-57.9%, the scores ranged between 0-56 points, and the mean score was 26 points. ② Scores of resident physicians were 0-56 points with a mean score of 26 points; attending physicians scored 6-50 points, with a mean score of 26 points; and chief physicians scored 6-50 points, with a mean score of 23 points. There were no significant differences among the various physicians (F = 0.771, t = 0.465, P > 0.05). CONCLUSION: Awareness among neurologists of intervention during secondary prevention of cerebral infarction/transient ischemia is not ideal. However, there was no significant difference between professional titles. | Ruihua Ma Chunxue Wang Xianwei Wang Yuhui Zhang Yongjun Wang Yilong Wang Xingquan Zhao Jingjing Li Ying Lu Mingjie Xu Zhuo Zhang Li Wang Weiwei Zhang Lang Lin Jiping Tan Yao Li Ming Wei Hongtao Li | 2008 | Neural Regeneration Research2008，3，3： | 2 |
| 9 | Generating mESC-derived insulin-producing cell lines through an intermediate lineage-restricted progenitor line显示文摘 | GuoDong Li Ruihua Luo Jiping Zhang Keng Suan Yeo Qizhou Lian Fei Xie Eileen Khia Way Tan Dorothée Caille Oi Lian Kon Manuel Salto-Tellez Paolo Meda Sai Kiang Lim | 2008 | Stem Cell Research2008，，1： | 1 |
| 10 | Asymmetric least squares for multiple spectra baseline correction显示文摘 | Peng Jiangtao Peng Silong Jiang An Wei Jiping Li Changwen Tan Jie | 2010 | Analytica Chimica Acta2010，667，： | 1 |
| 11 | Associations of particulate matter with dementia and mild cognitive impairment in China: A multicenter cross-sectional study显示文摘Ambient air pollution has been shown to be associated with the pathogenesis of dementia and mild cognitive impairment(MCI).However,few studies have examined these associations in well-characterized populations with low residential mobility,similar living habits,and a standardized assessment of both air pollution exposure and clinical outcome.This study examined the associations of long-term exposure to particulate matter(PM)air pollution with dementia and MCI,using data from the Chinese Veteran Clinical Research Platform.The cognitive function of elderly veterans from 277 communities in 18 Chinese cities was examined.Participants’daily exposures to aerodynamic diameters%2.5 mm(PM2.5)and%10 mm(PM10)during the 3 years prior to the survey were estimated using a satellite-based prediction.The adjusted odds ratios(ORs)and 95%confidence intervals of MCI associated with each 10 mg/m^(3) increase in PM2.5 and PM10 were 1.52(1.39,1.67)and 1.04(1.00,1.08),and those of dementia associated with PM2.5 and PM10 were 1.27(1.11,1.46)and 1.13(1.05,1.21),respectively.This demonstrates that long-term exposure to PM2.5 and PM10 can increase the prevalence of dementia/MCI among veterans in China.Higher ORs were observed for those with%9 years of educational attainment,those who actively attended physical activities,those who never smoked,former drinkers,and those who did not suffer from cerebral infarction.Improvement of ambient air quality,especially decreasing levels of PM2.5,may help to decrease the risk of dementia/MCI.Given the statistically significant association between PM and cognitive impairment demonstrated here,future studies should focus on examining the causal effect of PM pollution on dementia and MCI. | Jiping Tan Nan Li Xiaoxiao Wang Gongbo Chen Lailai Yan Luning Wang Yiming Zhao Shanshan Li Yuming Guo | 2021 | The Innovation2021，2，3： | 1 |
| 12 | Breaking efficiency limit of thermal concentrators by conductivity couplings显示文摘The concentrating efficiency of a thermal concentrator can be reflected in the ratio of its interior to exterior temperature gradients,which, however, has an upper limit in existing schemes. Here, we manage to break this upper limit by considering the couplings of thermal conductivities and improve the concentrating efficiency of thermal concentrators. For this purpose, we first discuss a monolayer scheme with an isotropic thermal conductivity, which can break the upper limit but is still restricted by its geometric configuration. To go further, we explore another degree of freedom by considering the monolayer scheme with an anisotropic thermal conductivity or by adding the second shell with an isotropic thermal conductivity, thereby making the concentrating efficiency completely free from the geometric configuration. Nevertheless, apparent negative thermal conductivities are required, and we resort to external heat sources realizing the same effect without violating the second law of thermodynamics. Finite-element simulations are performed to confirm the theoretical predictions, and experimental suggestions are also provided to improve feasibility. These results may have potential applications for thermal camouflage and provide guidance to other diffusive systems such as static magnetic fields and dc current fields for achieving similar behaviors. | Pengfei Zhuang Liujun Xu Peng Tan Xiaoping Ouyang Jiping Huang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，11： | 0 |
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