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| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | Energy-eMcient computing for wildlife tracking: design trade-offs and early experiences with ZebraNet显示文摘 | Juang P | 2002 | ACM SIGPLAN Notices2002，37，： | 1 |
| 3 | Alleviation effects of magnesium on copper toxicity and accumulation in grape- vine roots evaluated with biotic ligand models 显示文摘 | Chen B C Ho P C Juang K W | 2013 | Eco- toxicology2013，22，1： | 1 |
| 4 | Analysis, measurement and control of a new disc-type ultrasonic motor system显示文摘 | Juang P A Gu D W | 2006 | Mechatronics2006，16，1： | 1 |
| 5 | Energy-efficient Computing for Wildlife Tracking: Design Tradeoffs and Early Experiences with ZebraNet显示文摘 | Juang P Oki H Wang Yong | 2002 | SIGARCH Computer Architecture News2002，30，5： | 1 |
| 6 | Energy-efficient computing for wildlife tracking: design tradeoffs and early experiences with ZebraNet 显示文摘 | JUANG P OKI H WANG Y | 2002 | ACM Operating Systems Review2002，36，5： | 1 |
| 7 | Laparoscopic uterosacral nerve ablation with and without presacral neurectomy in the treatment of primary dysmenorrhea:a prospective efficacy anal- ysis显示文摘 | Juang C M Chou P Yen M S | 2007 | J Reprod Med2007，52，7： | 1 |
| 8 | Energy-efficient Computing for Wildlife Tracking:Design Trade-Offs and Early Experiences with ZebraNet 显示文摘 | Juang P | 2002 | ACM SIGPLAN Notices2002，37，： | 1 |
| 9 | Real time intranet-controlled virtual instrument multiple-circuit power monitoring显示文摘 | Young C P Juang W L Devaney M J | | 0，，03： | 1 |
| 10 | Mass transfer effect and intermediate detection for phenol degradation in immobilized Pseudomonas putida systems 显示文摘 | CHUNG T P TSENG H Y JUANG R S | 2003 | Process Biochem2003，38，10： | 1 |
| 11 | Treatment of polluted river water by a gravel contact oxidation system constructed under riverbed显示文摘 | JUANG D F TSAI W P LIU W K | 2008 | International Journal of Environmental Science & Technology2008，5，3： | 1 |
| 12 | Stable transfection of human prostate cancer cell line PC-3 with prostate specific antigen induces apoptosis both in-vivo and in-vitro显示文摘 | Balbay MD Juang P llansa N | 1999 | Proc Am Assoc Cancer Res1999，40，： | 1 |
| 13 | 50 Yearsof CODIC: algorithms,architectures,and applications显示文摘 | Meher P K Vails J Tso-Bing Juang | 2009 | IEEE Transactions on Circuits and Systems2009，56，9： | 1 |
| 14 | Use of thermally treated waste biological sludge as dye absorbent显示文摘 | ANNADURAI G JUANG R S YEN P S | 2003 | Advances in Environmental Research2003，7，： | 1 |
| 15 | Analysis,measurement and control of a new disc-type ultrasonic motor system显示文摘 | Juang P A Gu D W | | 0，，01： | 1 |
| 16 | Fidaxomicin : a macroeyclic antibiotic for the treatment of Clostridium difficile infection显示文摘 | HARDESTY JS JUANG P | 2011 | Pharmacotherapy2011，31，9： | 1 |
| 17 | 50 years of CORDIC:algorithms, architectures, and applications显示文摘 | Meher P K Valls J Juang T B | 2009 | IEEE Trans- actions on Circuits and Systems2009，56，9： | 1 |
| 18 | Energy-efficient computing for wildlife tracking:Design trade-offs and early experiences with ZebraNet显示文摘 | Juang P Oki H Wang Y | 2002 | ACM SIGARCH Computer Architecture News2002，37，10： | 1 |
| 19 | Laparoscopic uterosacral nerve ablation with and without presacral neurectomy in the treatment of primary dysmenorrhea: a prospective efficacy analysis 显示文摘 | Juang CM Chou P Yen MS | 2007 | J Reprod Med2007，52，7： | 1 |
| 20 | Phytotoxicity of soil tri-valent chromium to wheat seedlings evaluated by chelating resin extraction显示文摘 | Chen C P Lee D Y Juang K W | 2008 | Soil Science2008，173，9： | 1 |
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