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| 1 | Artificial Hair-Like Sensors Inspired from Nature: A Review显示文摘 | Zhiwu Han Linpeng Liu Kejun Wang Honglie Song Daobing Chen Ze Wang Shichao Niu Junqiu Zhang Luquan Ren | 2018 | Journal of Bionic Engineering2018，15，3： | 6 |
| 2 | Angle-dependent discoloration structures in wing scales of Morpho menelaus butterfly显示文摘The Morpho butterfly is famous for its typical structural color and has increasingly attracted the interest of scholars in a wide variety of research fields. Herein, it was found that the color of Morpho menelaus butterfly wings is not only structure-based but also viewing-angle-dependent. Firstly, the discoloration effect of this typical butterfly was confirmed by a series of experiments. Then, the general form, arrangements, and geometrical dimensions of the scales were observed using a stereomicroscope. Scanning electron microscopy was also used to examine the two-dimensional morphologies and structures of a single scale. Afterwards, one model with the optimized three-dimensional profile of the structure was described using Pro-engineer software. The associate model was then analyzed to reconstruct the process between the incident light and the model surface. Finally, the mechanism of the angle-dependent discoloration effect was analyzed by theoretical calculation and optical simulation. Different light propagation paths and the length of the incident light at different angles caused destructive or constructive interference between the light reflected from the different layers. The different spectra of the reflected light make the wings appear with different structural colors, thereby endowing the angle-dependent discoloration effect. The consistency of the calculation and simulation results confirms that these structures possess an excellent angle-dependent discoloration effect. This functional 'biomimetic structure' would not only be of great scientific interest but could also have a great impact in a wide range of applications such as reflective displays, credit card security, and military stealth technology. | NIU ShiChao LI Bo YE JunFeng MU ZhengZhi ZHANG JunQiu LIU Yan HAN ZhiWu | 2016 | Science China(Technological Sciences)2016，59，5： | 4 |
| 3 | Biosynthesis of selenosubtilisin: A novel way to target selenium into the active site of subtilisin显示文摘Glutathione peroxidase (GPx, EC1.11.1.9), an important anti-oxidative selenoenzyme, can catalyze the reduction of harmful hydroperoxides with concomitant glutathione, thereby protecting cells and other biological issues against oxidative damage. It captures considerable interest in redesign of its function for either the mechanism study or the pharmacological development as an antioxidant. In order to de- velop a general strategy for specifically targeting and operating selenium in active sites of enzymes, the catalytically essential residue selenocysteine (Sec) was first successfully bioincorporated into the catalytic center of subtilisin by using an auxotrophic expression system. The studies of the catalytic activity and the steady-state kinetics demonstrated that selenosubtilisin is an excellent GPx-like bio- catalyst. In comparison with the chemically modified method, biosynthesis exhibits obvious advan- tages: Sec could be site-directly incorporated into active sites of enzymes to overcome the non-speci- ficity generated by chemical modification. This study provides an important strategy for specifically targeting and operating selenium in the active site of an enzyme. | LI Jing LIU XiaoMan JI YueTong QI ZhenHui GE Yan XU JiaYun LIU JunQiu LUO GuiMin SHEN JiaCong | 2008 | Chinese Science Bulletin2008，53，16： | 3 |
| 4 | Atmospheric pollution of agriculture-oriented cities in Northeast China: A case in Suihua显示文摘Agriculture-oriented cities in Northeastern China have experienced frequent atmospheric pollution events.Deeper understandings of the pollution characteristics,haze causes and effects of management on local air quality are crucial for conducting integrated management approaches for the sustainable development of agriculture-oriented cities.Taking a typical agriculture-dominant city(i.e.,Suihua)in Northeast China,we analyzed in detail the characteristics and causes of atmospheric pollution and evaluated the straw-burning prohibition using multisource data.The results showed a clear temporal pattern of air quality index(AQI)on an annual scale(i.e.,2015-April 2019),with two typical pollution periods occurring in late autumn and early spring.The large areas of concentrated straw burning at local and regional scales accounted for the first period(i.e.,October and November),while dust emissions and farming disturbances comprised the second period.The interannual variation in pollution periods among these years was large,showing similar trends from 2015 to 2017 and the postponed late-autumn pollution period in 2018.Our evaluation has shown that the prohibition effect of straw burning significantly improved air quality in 2018,with a reduction of 59%±88%in the PM2.5 concentrations in October and November compared to 2015–2017.However,From October to April of the following year,the improvement effect was not significant due to postponement of straw burning to February or March.Our analysis also highlighted the roles of meteorological conditions,Therefore,combined with the promotion of straw utilization,scientifically prescribed burning considering the burning amount and location,meteorological conditions and regional transportation should be implemented. | Lili Li Kun Wang Weiwei Chen Qingliang Zhao Lijuan Liu Wei Liu Yang Liu Junqiu Jiang Jiumeng Liu Mengduo Zhang | 2020 | Journal of Environmental Sciences2020，32，11： | 3 |
| 5 | Recent advances in laser self-injection locking to high-Q microresonators显示文摘The stabilization and manipulation of laser frequency by means of an external cavity are nearly ubiquitously used in fundamental research and laser applications. While most of the laser light transmits through the cavity, in the presence of some back-scattered light from the cavity to the laser, the self-injection locking effect can take place, which locks the laser emission frequency to the cavity mode of similar frequency. The self-injection locking leads to dramatic reduction of laser linewidth and noise. Using this approach, a common semiconductor laser locked to an ultrahigh-Q microresonator can obtain sub-Hertz linewidth, on par with state-of-the-art fiber lasers. Therefore it paves the way to manufacture high-performance semiconductor lasers with reduced footprint and cost. Moreover, with high laser power, the optical nonlinearity of the microresonator drastically changes the laser dynamics, offering routes for simultaneous pulse and frequency comb generation in the same microresonator. Particularly, integrated photonics technology, enabling components fabricated via semiconductor CMOS process, has brought increasing and extending interest to laser manufacturing using this method. In this article, we present a comprehensive tutorial on analytical and numerical methods of laser self-injection locking, as well a review of most recent theoretical and experimental achievements. | Nikita M.Kondratiev Valery E.Lobanov Artem E.Shitikov Ramzil R.Galiev Dmitry A.Chermoshentsev Nikita Yu.Dmitriev Andrey N.Danilin Evgeny A.Lonshakov Kirill N.Min’kov Daria M.Sokol Steevy J.Cordette Yi-Han Luo Wei Liang Junqiu Liu Igor A.Bilenko | 2023 | Frontiers of physics2023，18，2： | 2 |
| 6 | A high-quality sponge gourd(Luffa cylindrica)genome显示文摘Sponge gourd(Luffa cylindrica)is an important cultivated vegetable and medicinal plant in the family Cucurbitaceae.In this study,a draft genome sequence of the sponge gourd inbred line P93075 was analyzed.Using Illumina,PacBio,and 10×Genomics sequencing techniques as well as new assembly techniques such as FALCON and chromatin interaction mapping(Hi-C),a chromosome-scale genome of approximately 656.19 Mb,with an N50 scaffold length of 48.76 Mb,was generated.From this assembly,25,508 protein-coding gene loci were identified,and 63.81%of the whole-genome consisted of transposable elements,which are major contributors to the expansion of the sponge gourd genome.According to a phylogenetic analysis of conserved genes,the sponge gourd lineage diverged from the bitter gourd lineage approximately 41.6 million years ago.Additionally,many genes that respond to biotic and abiotic stresses were found to be lineage specific or expanded in the sponge gourd genome,as demonstrated by the presence of 462 NBS-LRR genes,a much greater number than are found in the genomes of other cucurbit species;these results are consistent with the high stress resistance of sponge gourd.Collectively,our study provides insights into genome evolution and serves as a valuable reference for the genetic improvement of sponge gourd. | Haibin Wu Gangjun Zhao Hao Gong Junxing Li Caixia Luo Xiaoli He Shaobo Luo Xiaoming Zheng Xiaoxi Liu Jinju Guo Junqiu Chen Jianning Luo | 2020 | Horticulture Research2020，7，1： | 2 |
| 7 | Crack-based and Hair-like Sensors Inspired from Arthropods:A Review显示文摘Over a long period of time,arthropods evolve to have two excellent mechanical sensilla of slit sensilla and trichobothria sensilla,which construct a perfect perception system.The former mainly perceives the change of the in-the-plane force while the latter perceives that of the out-of-plane force.In recent years,these two sensilla have attracted researchers as the models for developing artificial mechanical sensors.This review mainly includes the biomechanics and biomimetic manufacturing techniques as well as their future application value.In order to better understand the advantages of biological strategies,this review describes the morphology,mechanical analysis,and information recognition of slit sensilla and trichobothria sensilla.Then this review highlights the recent development of Crack-based Sensors(CBSs)and Hair-like Sensors(HLSs)based on the analysis of biological mechanism.The manufacturing method and substrate of crack in CBS and those of hair rods in HLS are discussed respectively.Finally,the practical applications and potential value of two sensilla,such as flexible wearable electronic devices,robot sensing system,autopilot sensing and wind tunnel speed detection,are briefly discussed. | Changchao Zhang Junqiu Zhang Daobing Chen Xiancun Meng Linpeng Liu Kejun Wang Zhibin Jiao Tao Sun Dakai Wang Shichao Niu Zhiwu Han Luquan Ren | 2020 | Journal of Bionic Engineering2020，17，5： | 2 |
| 8 | Understanding enzyme catalysis by means of supramolecular artificial enzymes显示文摘Enzymes are biomacromolecules responsible for the abundant chemical biotransformations that sustain life. Recently, biochemists have discovered that multiple conformations and numerous parallel paths are involved during the processes catalyzed by enzymes. It is plausible that the entire macromolecular scaffold is involved in catalysis via cooperative motions that result in incredible catalytic efficiency. Moreover, some enzymes can very strongly bind the transition state with an association constant of up to 1024 M-1, suggesting that covalent bond formation is a possible process during the conversion of the transition state in enzyme catalysis, in addition to the concatenation of noncovalent interactions. Supramolecular chemistry provides fundamental knowledge about the relationships between the dynamic structures and functions of organized molecules. By tak-ing advantage of supramolecular concepts, numerous supramolecular enzyme mimics with complex and hierarchical structures have been designed and investigated. Through the study of supramolecular enzyme models, a great deal of information to aid our understanding of the mechanism of catalysis by natural enzymes has been acquired. With the development of supramolec-ular artificial enzymes, it is possible to replicate the features of natural enzymes with regards to their constitutional complexity and cooperative motions, and eventually decipher the conformation-based catalytic mystery of natural enzymes. | DONG ZeYuan ZHU JunYan LUO Quan LIU JunQiu | 2013 | Science China Chemistry2013，56，8： | 2 |
| 9 | Construction of Redox Responsive Vesicles Based on a Supra-Amphiphile for Enzyme Confinement显示文摘 | Tiezheng Pan Huixin Zou Hongcheng Sun Yao Liu Shengda Liu Quan Luo Zeyuan Dong Jiayun Xu Junqiu Liu | 2017 | Chinese Journal of Chemistry2017，35，6： | 2 |
| 10 | Dendritic tellurides acting as antioxidants显示文摘We have described the synthesis of a series of poly(aryl ether) dendrimers with telluride in the core and oligo(ethylene oxide) chains at the pe- riphery which act as glutathione peroxidase (GPx) mimics. These series of compounds were well characterized by H-NMR, 1 13C-NMR and ESI-MS. Using different ROOH (H2O2, cumene hydroperoxide) for testing the antioxidizing properties of these com- pounds, we have found that from generation 0 to 2, the activity of the dendritic GPx mimics first de- creased and then increased. This can be explained on the basis of a greater steric hindrance, going from generation 0 to 1, and stronger binding interactions going from generation 1 to 2. In other words, there exists a balance between binding interactions and steric hindrance that may optimize the GPx activity. | XU Huaping WANG Yapei WANG Zhiqiang LIU Junqiu Mario Smet Wim Dehaen | 2006 | Chinese Science Bulletin2006，51，19： | 1 |
| 11 | A Photo-responsive Catalytic Vesicle with GPx Activity显示文摘谷胱甘肽 peroxidase (GPx ) 是涉及反应的氧种类的减小的重要抗氧化剂酶并且保护房间免受氧化损坏的伤害。因而庞大的努力被奉献给与 GPx 功能开发人工的催化剂。而且,关于提高 GPx 的催化活动的研究模仿,聪明的 GPx 模型的设计和构造也启发了大兴趣。此处,一个新奇相片应答的包含硒的小囊的 GPx 模型成功地被构造由超分子有通过在水的媒介的恐水病、静电的相互作用的 benzeneseleninic 酸(PhSeO2H ) 的 cationic 表面活化剂 PyC10AzoC10Py 自己组装。这包含硒的小囊的催化剂显示出显著象 GPx 一样活动,它由 4-nitrobenzenethiol (NBT ) 是比为 cumene hydroperoxide (CUOOH ) 的减小的 PhSeO2H 更有效的 692 次。有趣地,当 CD 的 equimolar 数量被增加时,催化的泡的象 GPx 一样活动面对 CD 由于泡崩溃显著地衰退。而 biomimetic 系统被紫外光在 365 nm 照耀,催化的泡再被形成,象 GPx 一样活动恢复了。 | Ruiqing Xiao Lipeng Zhou Zeyuan Dong Yuzhou Gao Junqiu Liu | 2014 | Chinese Journal of Chemistry2014，32，1： | 1 |
| 12 | Carbon dots enhanced gelatin/chitosan bio-nanocomposite packaging film for perishable foods显示文摘Carbon dots(CDs)with intriguing fluorescent property,good biocompatibility,high stability,easy interaction with substrates,are burgeoning carbon nanoparticles with large potential in various applications.Incorporating CDs into the polymer matrix is becoming a popular strategy to endow the complex with new functions.Herein,the green-synthesized CDs was integrated into the mixture of gelatin(derived from waste fish scale)and chitosan,and a multifunctional bio-nanocomposite(defined as Gelatin/Chitosan/CDs)film was developed,which showed the excellent antibacterial,antioxidant,pH-sensitivity,UV shielding,and blue-emission properties.The effects of different concentrations of CDs on the physical,mechanical,structural,and functional activity of bio-nanocomposite film were tested.Compared with the Gelatin/Chitosan film,the Gelatin/Chitosan/CDs film with an optimum addition of 20%CDs showed the enhanced antibacterial,antioxidant as well as UV shielding activities.More importantly,it was used as an effective packaging material for fish meat preservation,reducing the loss of nutritional quality consumption,extending the shelf life of food.Besides,the bio-nanocomposite films also possessed the anti-counterfeiting and pH-responsive properties due to the strong fluorescent emission of CDs,and had the great potential in developing the intelligent packaging materials.Our work shed new light on the new application of CDs and the synthesis of bio-nanocomposite film in food industry. | Bofei Fu Qiaoling Liu Minghuan Liu Xiaofang Chen Hetong Lin Zongping Zheng Junqiu Zhu Congjie Dai Xiaochen Dong Da-Peng Yang | 2022 | Chinese Chemical Letters2022，33，10： | 1 |
| 13 | Broadband quasi-phase-matching in dispersion-engineered all-optically poled silicon nitride waveguides显示文摘Quasi-phase-matching(QPM)has become one of the most common approaches for increasing the efficiency of nonlinear three-wave mixing processes in integrated photonic circuits.Here,we provide a study of dispersion engineering of QPM second-harmonic(SH)generation in stoichiometric silicon nitride(Si3 N4)waveguides.We apply waveguide design and lithographic control in combination with the all-optical poling technique to study the QPM properties and shape the waveguide dispersion for broadband spectral conversion efficiency inside Si3 N4 waveguides.By meeting the requirements for maximal bandwidth of the conversion efficiency spectrum,we demonstrate that group-velocity matching of the pump and SH is simultaneously satisfied,resulting in efficient SH generation from ultrashort optical pulses.The latter is employed for retrieving a carrier-envelope-offset frequency of a frequency comb by using an f-2 f interferometric technique,where supercontinuum and SH of a femtosecond pulse are generated in Si3N4 waveguides.Finally,we show that the waveguide dispersion determines the QPM wavelength variation magnitude and sign due to the thermo-optic effect. | EDGARS NITISS BORIS ZABELICH OZAN YAKAR JUNQIU LIU RUI NING WANG TOBIAS J.KIPPENBERG AND CAMILLE-SOPHIE BRÈS | 2020 | Photonics Research2020，8，9： | 1 |
| 14 | Large Curvature Folding Strategies of Butterfly Proboscis显示文摘Due to its real-time control,high folding ratio,and structure self-locking,flexible large curvature self-folding devices have broad application prospects,such as foldable human implants,flexible electronics,and flexible robots.Driven by this background,flexible large curvature folding butterfly(Polyura eudamippus)proboscises were studied in this work.The folding ratio of the proboscises was about 15.The curvature of coiled proboscises ranged from about 150 m_1 to 880 m The external and internal structures of the proboscises were studied by different methods.Three main strategies for large-curvature folding of proboscises were identified:a gradual decrease in thickness,a lower elastic modulus,and(most importantly)large numbers of regular corrugated cracks arranged on the surface.These corrugated cracks can effectively accommodate the coiled strain and provide space for the large curvature folding of proboscises.Finally,a 4D printed coiled sample with corrugated cracks was fabricated to mimic the proboscises stretching process.Large-curvature folding strategies,based on these proboscises,provide insights for the biomimetic design of artificial highly folded components. | Daobing Chen Honglie Song Qingping Liu Jie Gan Yang Liu Keyu Che' Chong Wang Shifeng Wen Yan Zhou Chunze Yan Junqiu Zhang Yusheng Shi Zhiwu Han | 2020 | Journal of Bionic Engineering2020，17，6： | 1 |
| 15 | Micro/nano-scale Characterization and Fatigue Fracture Resistance of Mechanoreceptor with Crack-shaped Slit Arrays in Scorpion显示文摘The nocturnal scorpion Heterometrus petersii uses Basitarsal Compound Slit Sensilla (BCSS) as mechanoreceptor to detect mechanical signal (e.g. substrate vibration, cyclic loads caused by walking) without fatigue failure such as initiation of fatigue crack and further propagation of crack-shaped slit. The outstanding perceptive function has been discovered for over half a century. However, it is not yet clear about the microstructure, material composition and micromechanical property which are all important factors that determine the fatigue fracture resistance of the BCSS. Here, the microscopic characteristics of the BCSS were thoroughly studied. The results dicate that anti-fatigue resilin and stiff chitinous cuticle form multilayered composite as the main body of the BCSS. Meanwhile, the pre-existing slit as mechanosensory structure is covered by cuticular membrane which has different mechanical property with the epicuticle. Theoretical analysis shows that the structure-composition-property synergistic relations of composites confer on the BCSS with extreme fatigue fracture tolerance. | Kejun Wang Junqiu Zhang Yuqiang Fang Daobing Chen Linpeng Liu Zhiwu Han Luquan Ren | 2019 | Journal of Bionic Engineering2019，16，3： | 1 |
| 16 | 显示文摘 | Liu Junqiu Luo Guimin Shen Jiacong | 2000 | Biochimica et Bioph ysica Acta2000，1481，： | 1 |
| 17 | Soliton formation and spectral translation into visible on CMOS-compatible 4H-silicon-carbide-oninsulator platform显示文摘Recent advancements in integrated soliton microcombs open the route to a wide range of chip-based communication,sensing,and metrology applications.The technology translation from laboratory demonstrations to real-world applications requires the fabrication process of photonics chips to be fully CMOS-compatible,such that the manufacturing can take advantage of the ongoing evolution of semiconductor technology at reduced cost and with high volume.Silicon nitride has become the leading CMOS platform for integrated soliton devices,however,it is an insulator and lacks intrinsic second-order nonlinearity for electro-optic modulation.Other materials have emerged such as AlN,LiNbO_(3),AlGaAs and GaP that exhibit simultaneous second-and third-order nonlinearities.Here,we show that silicon carbide(SiC)--already commercially deployed in nearly ubiquitous electrical power devices such as RF electronics,MOSFET,and MEMS due to its wide bandgap properties,excellent mechanical properties,piezoelectricity and chemical inertia--is a new competitive CMOS-compatible platform for nonlinear photonics.High-quality-factor microresonators(Q=4×10^(6))are fabricated on 4H-SiC-on-insulator thin films,where a single soliton microcomb is generated.In addition,we observe wide spectral translation of chaotic microcombs from near-infrared to visible due to the second-order nonlinearity of SiC.Our work highlights the prospects of SiC for future low-loss integrated nonlinear and quantum photonics that could harness electro-opto-mechanical interactions on a monolithic platform. | Chengli Wang Jin Li Ailun Yi Zhiwei Fang Liping Zhou Zhe Wang Rui Niu Yang Chen Jiaxiang Zhang Ya Cheng Junqiu Liu Chun-Hua Dong Xin Ou | 2022 | Light(Science & Applications)2022，11，12： | 1 |
| 18 | 显示文摘 | LIU Junqiu WULFF G | 2004 | J Am Chem Soe2004，126，24： | 1 |
| 19 | Redefinition to bilayer osmotic pump tablets as subterranean river system within mini-earth via three-dimensional structure mechanism显示文摘Defining and visualizing the three-dimensional(3 D) structures of pharmaceuticals provides a new and important tool to elucidate the phenomenal behavior and underlying mechanisms of drug delivery systems. The mechanism of drug release from complex structured dosage forms, such as bilayer osmotic pump tablets, has not been investigated widely for most solid 3 D structures. In this study, bilayer osmotic pump tablets undergoing dissolution, as well as after dissolution in a desiccated solid state were examined, and visualized by synchrotron radiation micro-computed tomography(SR-μCT). In situ formed 3 D structures at different in vitro drug release states were characterized comprehensively. A distinct movement pattern of NaCl crystals from the push layer to the drug layer was observed, beneath the semi-permeable coating in the desiccated tablet samples. The 3 D structures at different dissolution time revealed that the pushing upsurge in the bilayer osmotic pump tablet was directed via peripheral“roadways”. Typically, different regions of the osmotic front, infiltration region, and dormant region were classified in the push layer during the dissolution of drug from tablet samples. According to the observed3 D microstructures, a “subterranean river model” for the drug release mechanism has been defined to explain the drug release mechanism. | Abi Maharjan Hongyu Sun Zeying Cao Ke Li Jinping Liu Jun Liu Tiqiao Xiao Guanyun Peng Junqiu Ji Peter York Balmukunda Regmi Xianzhen Yin Jiwen Zhang Li Wu | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 1 |
| 20 | Bioresponsive cisplatin crosslinked albumin hydrogel served for efficient cancer combination therapy显示文摘Combination therapy is one of the potential strategies for tackling complicated tumor treatments like drug resistance.In this work,we have generated a therapeutic cisplatin-crosslinked albumin hydrogel(BC-Gel)that allows the local release of L-Buthionine-sulfoximine(BSO),cisplatin,and glucose oxidase(GOx)with distinct release kinetics.The BC-Gel with favorable biostimuli degradability and injectability could release therapeutic agents in a programmed manner within the tumor microenvironment(TME).The preferentially released BSO significantly suppressed the glutathione(GSH)-related cisplatin resistance and sensitized the tumor cells to cisplatin by inhibiting theγ-glutamylcysteine synthetase.Meanwhile,cisplatin achieved a sequential release and long-term treatment following the bioresponsive gel degradation under the combined action of chloride ions(Cl−)and proteinase in the body.In addition,the overproduced H_(2)O_(2)of GOx-catalyzed glucose oxidation accelerated the depletion of existed GSH within cells and further weakened the cisplatin resistance,achieving enhanced tumor treatment together with a strong cell-killing effect.The above sequential drug release strategy based on the dual GSH depletion effect breaks the balance of the GSH-mediated redox TME and enhances the sensitivity of A549 cells to cisplatin forcefully,and provides a promising way for temporal control of drug release as well as efficient cancer combination therapy. | An Yan Zherui Zhang Jiamei Gu Xiaoran Ding Yongchen Chen Jingjing Du Shu Wei Hongcheng Sun Jiayun Xu Shuangjiang Yu Junqiu Liu | 2023 | Nano Research2023，16，2： | 1 |
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