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| 1 | Kinetics and equilibrium of adsorption of dissolved organic matter fractions from secondary effluent by fly ash显示文摘Fly ash was used as a low-cost adsorbent for removing dissolved organic matter (DOM) in secondary effluent. Batch experiments were conducted under various adsorbent dosages, pH, contact time, temperatures and DOM fractional characteristics. Under the optimum conditions of fly ash dosage of 15 g/L, temperature of 303 K and contact time of 180 min, a removal of 22.5% of the dissolved organic carbon (DOC), 23.7% of UV-254, 25.9% of the trihalomethanes precursors in secondary effluent was obtained. The adsorption of DOM fractions onto fly ash all followed the pseudo second-order kinetic model, and the hydrophilic fraction adsorption by fly ash also fitted the intraparticle diffusion model quite well. Freundlich and Langmuir models were applicable to the fly ash adsorption and their constants were evaluated. The maximum adsorption capacities of the adsorptions revealed that fly ash was more effective in adsorbing hydrophilic fraction than the acidic fractions. Structure changes of the DOM fractions after fly ash adsorption were also characterized via spectrum analyzing. Those mechanisms presented critical step toward improved efficiencies of fly ash adsorption via further surface-modification. | Liangliang Wei Kun Wang Qingliang Zhao Chunmei Xie Wei Qiu Ting Jia | 2011 | Journal of Environmental Sciences2011，23，7： | 21 |
| 2 | Micro/nano Indentation and Single Grit Diamond Grinding Mechanism on Ultra Pure Fused Silica显示文摘The existing research about ductile grinding of fused silica glass was mainly focused on how to carry out ductile regime material removal for generating very 'smoothed' surface and investigate the machining-induced damage in the grinding in order to reduce or eliminate the subsurface damage.The brittle/ductile transition behavior of optical glass materials and the wear of diamond wheel are the most important factors for ductile grinding of optical glass.In this paper,the critical brittle/ductile depth,the influence factors on brittle/ductile transition behavior,the wear of diamond grits in diamond grinding of ultra pure fused silica(UPFS) are investigated by means of micro/nano indentation technique,as well as single grit diamond grinding on an ultra-stiff machine tool,Tetraform 'C'.The single grit grinding processes are in-process monitored using acoustic emission(AE) and force dynamometer simultaneously.The wear of diamond grits,morphology and subsurface integrity of the machined groves are examined with atomic force microscope(AFM) and scanning electron microscope(SEM).The critical brittle/ductile depth of more than 0.5 μm is achieved.When compared to the using roof-like grits,by using pyramidal diamonds leads to higher critical depths of scratch with identical grinding parameters.However,the influence of grit shapes on the critical depth is not significant as supposed.The grinding force increased linearly with depth of cut in the ductile removal regime,but in brittle removal regime,there are large fluctuations instead of forces increase.The SEM photographs of the cross-section profile show that the median cracks dominate the crack patterns beneath the single grooves.Furthermore,The SEM photographs show multi worn patterns of diamond grits,indicating an inhomogeneous wear mechanism of diamond grits in grinding of fused silica with diamond grinding wheels.The proposed research provides the basal technical theory for improving the ultra-precision grinding of UPFS. | ZHAO Qingliang GUO Bing STEPHENSIN David CORBETT John | 2011 | Chinese Journal of Mechanical Engineering2011，24，6： | 10 |
| 3 | Application of ultra-sonication, acid precipitation and membrane filtration for co-recovery of protein and humic acid from sewage sludge显示文摘一个新奇方法被用于共同恢复从为液体化肥和动物的除去的污水污泥的蛋白质和腐殖的酸喂。在污水污泥的蛋白质首先用 ultrasonication 和酸降水的过程被提取,然后腐殖的酸经由膜过滤被恢复。抽取效率是 125.9 mg 腐殖的酸 ???????????????????????? 卓吗? | Liangliang WEI Kun WANG Xiangjuan KONG Guangyi LIU Shuang CUI Qingliang ZHAO Fuyi CUI | 2016 | Frontiers of Environmental Science & Engineering2016，10，2： | 9 |
| 4 | Fate of secondary effluent dissolved organic matter during soil-aquifer treatment显示文摘The reduction of mass and trihalomethane formation potential (THMFP) of dissolved organic matter (DOM) and its fractions from secondary effluent during laboratory-scale soil-aquifer treatment (SAT) soil columns were studied. Reduction in dissolved organic carbon (DOC), absorbance of ultraviolet light at 254 nm (UV-254), biodegradable dissolved organic carbon (BDOC) and nonbiodegradable dis- solved organic carbon (NBDOC) for the bulk DOM averaged 72.35%, 53.98%, 97.49% and 35.33% across the soil columns, respectively. Using XAD-8 and XAD-4 resins, DOM was fractionated into 3 fractions: hydrophobic acid (HPO-A), transphilic acid (TPI-A) and hydrophilic fraction (HPI). HPO-A was removed by 61.06%, TPI-A by 54.86% and HPI by 74.95% as DOC as a consequence of the laboratory-scale SAT, respectively. The reduction of THMFP from HPO-A, TPI-A and HPI was 27.24%, 26.24% and 36.08%, respectively. Proton nuclear magnetic resonance (1H-NMR) spectra revealed that the HPO-A isolated from the secondary effluent contained more aromatic functional groups than the corresponding TPI-A. Fourier-transform infrared (FT-IR) spectrum analysis illustrated that TPI-A had decreased hydrocarbon and increased aromatics content in the SAT columns. Specific ultraviolet light absorbance (SUVA) and specific THMFP for each DOM fraction increased across the soil columns and HPI exhibited greater increase in both than HPO-A and TPI-A. The most problematic THM precursor was found to be HPO-A with its high quantity present in recharged water and high chlorine reactivity. | XUE Shuang ZHAO QingLiang WEI LiangLiang WANG LiNa LIU ZhiGang | 2007 | Chinese Science Bulletin2007，52，18： | 8 |
| 5 | Gold nanoparticle/ZnO nanorod hybrids for enhanced reactive oxygen species generation and photodynamic therapy显示文摘金 nanoparticle (Au NP )@ ZnO nanorod (NR )(Au@ZnO ) 有各种各样的 ZnO 的混血儿: Au 臼齿的比率被开发在光力学的治疗(太平洋夏季时间) 提高反应的氧种类(ROS ) 的产生应用程序。介绍在 Au NP 和 ZnO NR 之间的一个金属 / 半导体 heterostructure 接口调制了电子转移在下面紫外(紫外) 照耀,它戏剧性地在 ZnO 压制了电子洞再结合并且同时在 Au NP 表面与高精力增加了激动的电子的数量。因此, nanohybrid 的 ROS 收益更加独自太古的 Au NP 或 ZnO NR 在那些上被改进并且表明了 1 + 1 > 2 效果。这改进随混血儿的 Au 的比例的增加被加强。结果证明有 ZnO 的 Au@ZnO nanohybrids : 因为他们有在 Au 和 ZnO 之间的最大的接口区域, 20:1 的 Au 比率产生了最高的 ROS 收益,它接着在太平洋夏季时间期间为 HeLa 和 C2C12 房间导致了最低房间生存能力。而且, ROS 产生和房间破坏断然与 nanohybrid 剂量被相关。Au@ZnO 混血儿(20:1, 100 g/mL ) 导致了为 2 min 象 28% 一样在紫外暴露以后低的 HeLa 房间生存能力,它显示了它的有希望的潜力改进太平洋夏季时间的治疗学的功效。 | Zhuo Kang Xiaoqin Yan Lanqing Zhao Qingliang Liao Kun Zhao Hongwu Du Xiaohui Zhang Xueji Zhang Yue Zhang | 2015 | Nano Research2015，8，6： | 7 |
| 6 | Trihalomethane formation potential of organic fractions in secondary effluent显示文摘有机物被知道是众多的氯化副产品的先锋。在从 Wenchang 废水处理的第二等的自河的有机物种(哈尔滨,中国)身体上被分开成下列 fractions:particulate 器官的碳( 1.2-0.45 亩 m ),胶体的器官的碳( 0.45-0.1 亩 m ),好胶体的器官的碳( 0.1-0.025 亩 m ),并且溶解了器官的碳(文档)( <0.025 亩 m )。而且, <0.45 瓮部分化学上被分开成恐水病的酸(HPO -- 一) ,恐水病中立(HPO-N ) , transphilic 酸(TPI -- 一) , transphilic 中立(TPI-N ) ,并且吸水的部分(HPI ) 。从尺寸和 XAD 分别获得的这些器官的部分的氯反应被评估。结构并且 HPO 的化学组成 -- 一, HPO-N, TPI -- A,和 TPI-N 孤立用元素的分析(C, H, O,和 N ) 被描绘, Fourier 变换红外线的光谱学(FT-ER ) ,和质子原子磁性的回声光谱学(~ 1H-NMR ) 。结果证明文档以全部的集中和 trihalomethane 形成潜力( THMFP )是主导的,并且在特定的 THMFP ( STHMFP )和特定的紫外光没有统计差别吸收度在之中 0.45,0.1 ,并且 0.025 亩 m filtrates.HPO -- A 与另外的化学 fractions.HPO 相比有最高的 STHMFP --一, HPO-N , TPI -- A ,和 TPI-N 包含了氮的3.02%-3.52%。H/C 的臼齿的比率在 HPO 的顺序增加了 -- 一 < HPO-N < TPI -- 一 < TPI-N.THE 与比更显著地 < br 在里面比较了为是当相对有那些证明其它显示了更高更大的高分析比率,这增加了部分。组织功能的包含氧的包含的 content.TPI-N C-H 脂肪族的 TPI-N HPO-N, TPI -- 一,并且而内容 C 芳香的 HPO -- A 部分四 HPO -- 一 < HPO-N < TPI -- 一 < TPI-N.FT-IR 顺序质子其它。相对 fractions.~1H-NMR O > | XUE Shuang ZHAO Qingliang WEI Liangliang JIA Ting | 2008 | Journal of Environmental Sciences2008，20，5： | 5 |
| 7 | Fluorescence spectroscopic studies of the effect of granular activated carbon adsorption on structural properties of dissolved organic matter fractions显示文摘这个工作在第二等的自河在溶解有机物( DOM )的荧光特征上调查了小粒的激活的碳吸附( GACA )的效果,借助于刺激排放矩阵( EEM )系列,荧光地区性的集成(星期五)方法,同步系列,在刺激在 500 nm 在波长 450 nm 定义为荧光排放紧张的比率到那的荧光索引(<潜水艇class=“ a-plus-plus ”>前)=通信的 370 nm ,和波长 t 在从北方废水处理工厂的第二等的自河的 DOM (沈阳,中国) 是用进 5 部分的 XAD 树脂的 fractionated:恐水病的酸(HPO -- 一) ,恐水病中立(HPO-N ) , transphilic 酸(TPI -- 一) , transphilic 中立(TPI-N ) 并且吸水的部分(HPI ) 。结果显示出那荧光灯在 HPO-N 和 TPI-N 的材料被 GACA 不太乐意地在另外的部分比那些移开。相对内容荧光灯在 HPO 的材料 -- 一, TPI -- 而那作为 GACA 的后果在 HPO-N 和 TPI-N 增加了, A 和 HPI 减少了。在所有 DOM 部分的多不的 aromatics 被 GACA 优先地吸收,与表示为文档的体积 DOM 比较。在另一方面,芳香的氨基酸的吸附和由 GACA 在同步系列展出荧光山峰的腐殖的像酸的 fluorophores 似乎依赖于 DOM 部分的酸 / 中立性质。所有五部分减少了由于 GACA 的荧光索引。GACA 导致了一减少 < 潜水艇 class= “ a-plus-plus ” > 为 HPO 的 0.5 价值 -- 一,增加 < 潜水艇 class= “ a-plus-plus ” > 为 HPO-N 的 0.5 价值, TPI -- A 和 HPI,并且一一致 < 潜水艇 class= “ a-plus-plus ” > 为 TPI-N 的 0.5 价值。 | Shuang XUE Qingliang ZHAO Liangliang WEI Xiujuan HUI Xiping MA Yingzi LIN | 2012 | Frontiers of Environmental Science & Engineering2012，6，6： | 5 |
| 8 | MICRO/NANO-MACHINING ON SILICON SURFACE WITH A MODIFIED ATOMIC FORCE MICROSCOPE显示文摘To understand the deformation and removal mechanism of material on nano-scale at ultralow loads,a systemic study on AFM micro/nano-machining on single crystal ailicon is conducted. The results indicate that AFM nano- machining has a precisely dimensional controllability and a good surface quality on nanometer scale.A SEM is adopted to observe nano-machined region and chips,the results indicate that the material removal mechanisms change with the applied normal load. An XPS is used to analyze the changes of chemical composition inside and outside the nano-machined region respectively.The nano-indentation which is conducted with the same AFM diamond tip on the machined region shows a big discrepancy compared with that on the macro-scale. The calculated results show higher nano-hardness and elastic modulus than normal values .This phenomenon on be regarded as the indentation size effect(ISE). | Zhao Qingliang,Sun Tao,Dong Shen,Liang Yingchun (School of Mechanical Engineering,Harbin Institute of Technology) | 2001 | Chinese Journal of Mechanical Engineering2001，14，3： | 4 |
| 9 | Development, applications, and future directions of triboelectric nanogenerators显示文摘 | Mingyuan Ma Zhuo Kang Qingliang Liao Qian Zhang Fangfang Gao Xuan Zhao Zheng Zhang Yue Zhang | 2018 | Nano Research2018，11，6： | 4 |
| 10 | Removal and transformation of organic matters in domestic wastewater during lab-scale chemically enhanced primary treatment and a trickling filter treatment显示文摘To find a simple and economical way for treating the domestic wastewater in small counties and towns, a process combining chemically enhanced primary treatment and a trickling filter (CEPT-TF, representing the physical and biological effects) was constructed and operated in laboratory conditions. The characteristic behaviors of dissolved organic matter in raw wastewater and effluents were examined during steady-state operation. Experimental results showed that the process of CEPT and TF in series was beneficial for the removal of hydrophobic and hydrophilic organics. Specially, the hydrophobic and aromatic materials could be preferentially removed in the CEPT unit, and the hydrophilic fraction in the TF. Structural changes of the organic fractions during the operation of the different units were also characterized via spectrum analysis. | Qingliang Zhao Huiyuan Zhong Kun Wang Liangliang Wei Jinli Liu Yu Liu | 2013 | Journal of Environmental Sciences2013，25，1： | 4 |
| 11 | Transformation of erythromycin during secondary effluent soil aquifer recharging:Removal contribution and degradation path显示文摘Erythromycin(ERY),a widely used antibiotic,has recently been detected in municipal secondary effluents and poses serious threats to human health during wastewater reusing.In this study,the removal,fate,and degradation pathway of ERY in secondary effluent during soil aquifer treatment was evaluated via laboratory-scale SAT tests.Up to a 92.9%reduction of ERY in synthetic secondary effluent was observed in 1.0 m depth column system,which decreased to 64.7%when recharged with wastewater treatment plant secondary effluent.XRD-fractionation results demonstrated that the transphilic acid and hydrophobic acid fractions in secondary effluent compete for the adsorption sites of the packed soil and lead to a declined ERY removal.Moreover,aerobic biodegradation was the predominant role for ERY removal,contributing more than 60%reduction of ERY when recharged with synthetic secondary effluent.Destruction of 14-member macrocyclic lactone ring and breakdown of two cyclic sugars(L-cladinose and D-desosamine) were main removal pathways for ERY degradation,and produced six new intermediates. | Liangliang Wei Kena Qin Ningbo Zhao Daniel R.Noguera Wei Qiu Qingliang Zhao Xiangjuan Kong Weixian Zhang Felix Tetteh Kabutey | 2017 | Journal of Environmental Sciences2017，29，1： | 4 |
| 12 | Mechanism on minimization of excess sludge in oxic-settling- anaerobic (OSA) process显示文摘The oxic-settling-anaerobic(OSA)process is a promising wastewater treatment technique for efficiently reducing sludge production and improving the stability of process operation.In this paper,the possible factors of sludge reduction such as sludge decay,uncoupled metabol-ism,and anaerobic oxidation with low sludge production were discussed in the OSA process.It has been confirmed that sludge decay is the decisive cause in the OSA process,accounting for 66.7%of sludge production reduction.Sludge decay includes hydrolysis and acidogenesis of dead microorganisms and particle organic carbon adsorbed in sludge floc and endogenous metabolism.By batch experi-ments,it has been proven that there is energetic uncoupling in the OSA system since microorganisms were exposed to alternative anaerobic and aerobic environment.It accounts for about 7.5%of sludge production reduction.Soluble chemical oxygen demand(SCOD)released from the anaerobic sludge tank in the OSA process was used as the substrate for cryptic growth.The substrate was used for anoxic denitrifying,anaerobic phosphorus release,sulfate reduction,and methane production.These anaerobic reactions in the sludge anaerobic tank have lower sludge production than in the aerobic oxidation when equivalent SCOD is consumed,which may lead to approximately 23%of sludge reduction in the OSA process.It has been concluded that multiple causes resulted in the minimization of excess sludge in the OSA system.The microbial community structure and diversity of sludge samples from the CAS(conventional activated sludge)and OSA systems were investigated by 16 SrDNA PCR-DG-DGGE(poly-merase chain reaction-double gradient-denaturing gradient gel electrophoresis).DGGE profile and cluster analysis showed more abundant species in the OSA system contrasting to microbial communities in the CAS system. | Jianfang WANG Qingliang ZHAO Wenbiao JIN Jikan LIN | 2008 | Frontiers of Environmental Science & Engineering2008，2，1： | 3 |
| 13 | Atmospheric pollution of agriculture-oriented cities in Northeast China: A case in Suihua显示文摘Agriculture-oriented cities in Northeastern China have experienced frequent atmospheric pollution events.Deeper understandings of the pollution characteristics,haze causes and effects of management on local air quality are crucial for conducting integrated management approaches for the sustainable development of agriculture-oriented cities.Taking a typical agriculture-dominant city(i.e.,Suihua)in Northeast China,we analyzed in detail the characteristics and causes of atmospheric pollution and evaluated the straw-burning prohibition using multisource data.The results showed a clear temporal pattern of air quality index(AQI)on an annual scale(i.e.,2015-April 2019),with two typical pollution periods occurring in late autumn and early spring.The large areas of concentrated straw burning at local and regional scales accounted for the first period(i.e.,October and November),while dust emissions and farming disturbances comprised the second period.The interannual variation in pollution periods among these years was large,showing similar trends from 2015 to 2017 and the postponed late-autumn pollution period in 2018.Our evaluation has shown that the prohibition effect of straw burning significantly improved air quality in 2018,with a reduction of 59%±88%in the PM2.5 concentrations in October and November compared to 2015–2017.However,From October to April of the following year,the improvement effect was not significant due to postponement of straw burning to February or March.Our analysis also highlighted the roles of meteorological conditions,Therefore,combined with the promotion of straw utilization,scientifically prescribed burning considering the burning amount and location,meteorological conditions and regional transportation should be implemented. | Lili Li Kun Wang Weiwei Chen Qingliang Zhao Lijuan Liu Wei Liu Yang Liu Junqiu Jiang Jiumeng Liu Mengduo Zhang | 2020 | Journal of Environmental Sciences2020，32，11： | 3 |
| 14 | Precision Grinding of Reaction Bonded Silicon Carbide Using Coarse Grain Size Diamond Wheels显示文摘Reaction bonded SiC(RBSiC) is attractive for optical application because of its favorable properties and low fabrication cost. However, the difficultness and cost involved in RBSiC grinding limit its application. The investigation on high efficient and low-cost machining with good grinding quality is desired. Generally, high efficient machining for RBSiC is realized by using coarse grain size grinding wheels, but serious grinding damage is inevitable. In this paper, monolayer nickel electroplated coarse grain size diamond grinding wheels with grain sizes of 46 μm, 91 μm, and 151 μm were applied to the grinding of RBSiC. An electrolytic in-process dressing(ELID) assisted conditioning technique was first developed by using cup shape copper bonded conditioning wheels with grain sizes of 15 μm and 91 μm to generate the conditioned coarse grain size wheels with minimized wheel run-out error within 2 μm, constant wheel peripheral envelop as well as top-flattened diamond grains. Then, the grinding experiments on RBSiC were carried out to investigate the grinding performance and material removal mechanism. The experimental results indicate that the developed conditioning technique is applicable and feasible to condition the coarse grain size diamond wheels under optimal conditioning parameters, and the material removal mechanism involved in RBSiC grinding is the combination of brittle fracture and ductile deformation to generate smooth ground surface. This research is significant for the high efficient and low-cost precision grinding of RBSiC with good ground surface quality. | ZHAO Qingliang CHEN Junyun BRINKSMEIER E | 2010 | Chinese Journal of Mechanical Engineering2010，23，3： | 3 |
| 15 | Plant buffering against the high-light stress- induced accumulation of CsGA2ox8 transcripts via alter native splici ng to fi n ely tune gibberelli n levels and maintain hypocotyl elongation显示文摘In plants,alternative splicing(AS)is markedly induced in response to environmental stresses,but it is unclear why plants generate multiple transcripts under stress conditions.In this study,RNA-seq was performed to identify AS events in cucumber seedlings grown under different light intensities.We identi fi ed a novel transcript of the gibberellin(GA)-deactivating enzyme Gibberellin 2-beta-dioxygenase 8(CsGA2ox8).Compared with canonical CsGA2ox8.1,the CsGA2ox8.2 isoform presented intron retention between the second and third exons.Functional analysis proved that the transcript of CsGA2ox8.1 but not CsGA2ox8.2 played a role in the deactivation of bioactive GAs.Moreover,expression analysis demonstrated that both transcripts were upregulated by increased light intensity,but the expression level of CsGA2ox8.1 increased slowly when the light intensity was>400μmol-m-2-s-1 PPFD(photosynthetic photon fl ux density),while the CsGA2ox8.2 transcript levels increased rapidly when the light intensity was>200 pmol-m-2-s-1 PPFD.Our fi ndings provide evidence that plants might fi nely tune their GA levels by buffering against the normal transcripts of CsGA2ox8 through AS. | Bin Liu Shuo Zhao Pengli Li Yilu Yin Qingliang Niu Jinqiang Yan Danfeng Huang | 2021 | Horticulture Research2021，8，1： | 2 |
| 16 | A review of ARGs in WWTPs:Sources,stressors and elimination显示文摘Antibiotic re sistance genes(ARGs)in aquatic enviro nments,which seriously endanger human health and ecological safety,have become a worldwide concern due to their easy diffusion and proliferation.Wastewater treatment plants(WWTPs),which receive resistant bacteria and ARGs from a wide variety of sources(i.e.,livestock farms,hospitals,antibiotic manufactures,and households),are regarded as important emission sources of aquatic ARGs.This review presents a quantitative profile of the majority sources of ARGs in the influent of WWTPs and discusses the potential factors that affect the concentration distribution of ARGs.Specifically,a noteworthy existence of ARGs,which ranged from 1 E+05 to 1 E+11 copies/mL,was detected in livestock breeding wastewater,and household wastewater(caused by the unlimited utilization of antibiotics)was determined to be the predominant contributor of ARGs in WWTPs.We summarized the selective pressure on ARGs and determined the positive correlation of the concentration of ARGs and the existence of many containments,including antibiotics,heavy metals(Zn and Cu were frequently reported),quaternary ammonium compounds,etc.In the last section,physical,chemical,and biological treatments for the removal of ARGs and their effluent in WWTPs are discussed and prospective future studies are summarized. | Kena Qin Liangliang Wei Jianju Li Bo Lai Fengyi Zhu Hang Yu Qingliang Zhao Kun Wang | 2020 | Chinese Chemical Letters2020，31，10： | 2 |
| 17 | Textbook Outcome as a measure of surgical quality assessment and prognosis in gastric neuroendocrine carcinoma:A large multicenter sample analysis显示文摘Objective:Quality assurance is crucial for oncological surgical treatment assessment.For rare diseases,singlequality indicators are not enough.We aim to develop a comprehensive and reproducible measurement,called the'Textbook Outcome'(TO),to assess the quality of surgical treatment and prognosis of gastric neuroendocrine carcinoma(G-NEC)patients.Methods:Data from patients with primary diagnosed G-NEC included in 24 high-volume Chinese hospitals from October 2005 to September 2018 were analyzed.TO included receiving a curative resection,≥15 lymph nodes examined,no severe postoperative complications,hospital stay≤21 d,and no hospital readmission≤30 d after discharge.Hospital variation in TO was analyzed using a case mix-adjusted funnel plot.Prognostic factors of survival and risk factors for non-Textbook Outcome(non-TO)were analyzed using Cox and logistic models,respectively.Results:TO was achieved in 56.6%of 860 G-NEC patients.TO patients had better overall survival(OS),disease-free survival(DFS),and recurrence-free survival(RFS)than non-TO patients(P<0.05).Moreover,TO patients accounted for 60.3%of patients without recurrence.Multivariate Cox analysis revealed non-TO as an independent risk factor for OS,DFS,and RFS of G-NEC patients(P<0.05).Increasing TO rates were associated with improved OS for G-NEC patients,but not hospital volume.Multivariate logistic regression revealed that nonlower tumors,open surgery,and>200 mL blood loss were independent risk factors for non-TO patients(P<0.05).Conclusions:TO is strongly associated with multicenter surgical quality and prognosis for G-NEC patients.Factors predicting non-TO are identified,which may help guide strategies to optimize G-NEC outcomes. | Qiyue Chen Zhongliang Ning Zhiyu Liu Yanbing Zhou Qingliang He Yantao Tian Hankun Hao Wei Lin Lixin Jiang Gang Zhao Ping Li Chaohui Zheng Changming Huang on behalf of the Study Group for Gastric Neuroendocrine Tumors | 2021 | Chinese Journal of Cancer Research2021，33，4： | 2 |
| 18 | Low phosphorus promotes NSP1–NSP2 heterodimerization to enhance strigolactone biosynthesis and regulate shoot and root architecture in rice显示文摘Phosphorus is an essential macronutrient for plant development and metabolism,and plants have evolved ingenious mechanisms to overcome phosphate(Pi)starvation.However,the molecular mechanisms underlying the regulation of shoot and root architecture by low phosphorus conditions and the coordinated utilization of Pi and nitrogen remain largely unclear.Here,we show that Nodulation Signaling Pathway 1(NSP1)and NSP2 regulate rice tiller number by promoting the biosynthesis of strigolactones(SLs),a class of phytohormones with fundamental effects on plant architecture and environmental responses.We found that NSP1 and NSP2 are induced by Oryza sativa PHOSPHATE STARVATION RESPONSE2(OsPHR2)in response to low-Pi stress and form a complex to directly bind the promoters of SL biosynthesis genes,thus markedly increasing SL biosynthesis in rice.Interestingly,the NSP1/2–SL signaling module represses the expression of CROWN ROOTLESS 1(CRL1),a newly identified early SL-responsive gene in roots,to restrain lateral root density under Pi deficiency.We also demonstrated that GR24^(4DO) treatment under normal conditions inhibits the expression of OsNRTs and OsAMTs to suppress nitrogen absorption but enhances the expression of OsPTs to promote Pi absorption,thus facilitating the balance between nitrogen and phosphorus uptake in rice.Importantly,we found that NSP1p:NSP1 and NSP2p:NSP2 transgenic plants show improved agronomic traits and grain yield under low-and medium-phosphorus conditions.Taken together,these results revealed a novel regulatory mechanism of SL biosynthesis and signaling in response to Pi starvation,providing genetic resources for improving plant architecture and nutrient-use efficiency in low-Pi environments. | Kun Yuan Hao Zhang Chaoji Yu Nan Luo Jijun Yan Shuang Zheng Qingliang Hu Dahan Zhang Liquan Kou Xiangbing Meng Yanhui Jing Mingjiang Chen Xinwei Ban Zongyun Yan Zefu Lu Jian Wu Yu Zhao Yan Liang Yonghong Wang Guosheng Xiong Jinfang Chu Ertao Wang Jiayang Li Bing Wang | 2023 | Molecular Plant2023，16，11： | 2 |
| 19 | Electricity generation from bio-treatment of sewage sludge with microbial fuel cell显示文摘 | Junqiu Jiang Qingliang Zhao Jinna Zhang Guodong Zhang Duu-Jong Lee | 2009 | Bioresource Technology2009，，23： | 2 |
| 20 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
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