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| 1 | Fusions between dendritic cells and whole tumor cells as anticancer vaccines显示文摘 | Shigeo Koido Sadamu Homma Masato Okamoto Yoshihisa Namiki Kazuki Takakura Kan Uchiyama Mikio Kajihara Seiji Arihiro Hiroo Imazu Hiroshi Arakawa Shin Kan Hideo Komita Masaki Ito Toshifumi Ohkusa Jianlin Gong Hisao Tajiri | 2013 | OncoImmunology2013，，： | 3 |
| 2 | Current Immunotherapeutic Approaches in Pancreatic Cancer显示文摘 | Shigeo Koido Sadamu Homma Akitaka Takahara Yoshihisa Namiki Shintaro Tsukinaga Jimi Mitobe Shunichi Odahara Toyokazu Yukawa Hiroshi Matsudaira Keisuke Nagatsuma Kan Uchiyama Kenichi Satoh Masaki Ito Hideo Komita Hiroshi Arakawa Toshifumi Ohkusa Jianlin Go | 2011 | Clinical and Developmental Immunology2011，，： | 3 |
| 3 | Production of corticotropin-releasing factor and urocortin from human monocyte-derived dendritic cells is stimulated by commensal bacteria in intestine显示文摘AIM:To examine whether commensal bacteria are a contributing cause of stress-related mucosal inflammation.METHODS:Human peripheral blood monocyte-deriveddendritic cells(MoDCs)were stimulated by commensal bacterial strains,including Escherichia coli,Clostridium clostridioforme,Bacteroides vulgatus(B.vulgatus),Fusobacterium varium(F.varium),and Lactobacillus delbrueckii subsp.bulgaricus.After incubation,corticotropin-releasing factor(CRF)and urocortin 1(UCN1)mRNA in the cells was examined by real-time reverse transcription polymerase chain reaction.Supernatants from the cells were tested for CRF and UCN1 using an enzyme-linked immunosorbent assay.RESULTS:Both CRF and UCN1 were significantly augmented by B.vulgatus and F.varium at both the mRNA and protein levels.In particular,B.vulgatus stimulated human MoDCs,resulting in extremely high levels of CRF and UCN1.CONCLUSION:Stimulation of MoDCs by B.vulgatus and F.varium may be associated with CRF/UCN1-related intestinal disorders,such as irritable bowel syndrome and inflammatory bowel disease. | Shigeo Koido Toshifumi Ohkusa Shin Kan Kazuki Takakura Keisuke Saito Hideo Komita Zensho Ito Hiroko Kobayashi Shinichiro Takami Kan Uchiyama Hiroshi Arakawa Masaki Ito Masato Okamoto Mikio Kajihara Sadamu Homma Hisao Tajiri | 2014 | World Journal of Gastroenterology2014，20，39： | 2 |
| 4 | Immunotherapy synergizes with chemotherapy targeting pancreatic cancer显示文摘 | Shigeo Koido Sadamu Homma Akitaka Takahara Yoshihisa Namiki Hideo Komita Kan Uchiyama Masaki Ito Jianlin Gong Toshifumi Ohkusa Hisao Tajiri | 2012 | Immunotherapy2012，，1： | 2 |
| 5 | Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions显示文摘 | Shigeo Koido Sadamu Homma Eiichi Hara Yoshihisa Namiki Akitaka Takahara Hideo Komita Eijiro Nagasaki Masaki Ito Toshifumi Ohkusa Jianlin Gong Hisao Tajiri E. Shevach | 2010 | Clinical and Developmental Immunology2010，，： | 2 |
| 6 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK-432, a streptococcal preparation 显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer Immunol Immunother2007，56，8： | 1 |
| 7 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK-432,a streptococcal preparation显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer Immunol Immunother2007，56，8： | 1 |
| 8 | Interferon-gamma produced by interleukin-12 activated tumor infiltrating CD8+ T cells directly induces apoptosis of mouse hepatocellular carcinoma显示文摘 | Homma S Saotome H | 2006 | J Hepatol2006，45，5： | 1 |
| 9 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK - 432, a streptococcal preparation 显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer Immunol Immunother2007，56，8： | 1 |
| 10 | Mechanism of anti-tumor effect on mouse hepatocellular carcinoma by intra-tumoral injection of OK-432,a streptococcal preparation显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer Immunol Immunother2007，56，8： | 1 |
| 11 | First trimester 3D volumetry. Association of the gestational volumes with the birth weight显示文摘 | Aris Antsaklis Eleftherios Anastasakis Ourania Komita Marianna Theodora Petros Hiridis George Daskalakis | 2011 | Journal of Maternal-Fetal and Neonatal Medicine2011，，8： | 1 |
| 12 | Dendritic/pancreatic carcinoma fusions for clinical use: Comparative functional analysis of healthy- versus patient-derived fusions显示文摘 | Shigeo Koido Eiichi Hara Sadamu Homma Yoshihisa Namiki Hideo Komita Akitaka Takahara Eijiro Nagasaki Masaki Ito Yukiko Sagawa Makoto Mitsunaga Kan Uchiyama Kenichi Satoh Seiji Arihiro Toshifumi Ohkusa Jianlin Gong Hisao Tajiri | 2010 | Clinical Immunology2010，，3： | 1 |
| 13 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK432, a streptococcal preparation显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer lmmunol Immunother2007，56，8： | 1 |
| 14 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK-432, a Streptococcal preparation 显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer Immunol Immunother2007，56，8： | 1 |
| 15 | Interferon-gamma produced by interleukin-12-activated tumor infiltrating CD8+T cells directly induces apoptesis of mouse hepatocellular carcinoma显示文摘 | Komita H Homma S Saotome H | 2006 | J Hepatol2006，45，5： | 1 |
| 16 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK-432,a streptococcal preparation显示文摘 | Homma S Sagawa Y Komita H | 2007 | Cancer Immunol Imm-unother2007，56，8： | 1 |
| 17 | Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injec-tion of OK-432,a streptococcal preparation显示文摘 | Homma S Sagawa Y Komita H | | 0，，8： | 1 |
| 18 | Conditional interleukin-12 gene therapy promotes safe and effective antitumor immunity显示文摘 | Komita H Zhao X Katakam A K | 2009 | Cancer Gene Ther2009，16，12： | 1 |
| 19 | Interferon-gamma produced by interleukin-12-activated tumor infiltrating CD8 + T cells directly induces apoptosis of mouse hepatocellular carcinoma显示文摘 | Hideo Komita Sadamu Homma Hideo Saotome Mikio Zeniya Tsuneya Ohno Gotaro Toda | 2006 | Journal of Hepatology2006，，： | 1 |
| 20 | Interferon-gamma produced by interleukin-12-activated tumor infiltrating CD8 ( + ) T cells directly induces apoptosis of mouse hepatocellular carcinoma 显示文摘 | Komita H Homma S Saotome H | 2006 | J Hepatol2006，45，5： | 1 |
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