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| 1 | The first offshore natural gas hydrate production test in South China Sea显示文摘Natural gas hydrates (NGH)is one of key future clean energy resources.Its industrialized development will help remit the huge demand of global natural gas,relieve the increasing pressure of the environment, and play a vital role in the green sustainable growth of human societies.Based on nearly two decades' studying on the reservoir characteristics in the South China Sea (SCS)and the knowledge of reservoir system,the China Geological Survey (CGS)conducted the first production test on an optimal target selected in Shenhu area SCS in 2017.Guided by the 'three-phase control'exploitation theory which focused on formation stabilization,technologies such as formation fluid extraction,well drilling and completing, reservoir stimulating,sand controlling,environmental monitoring,monitoring and preventing of secondary formation of hydrates were applied.The test lasted for 60 days from May 10^th when starting to pump, drop pressure and ignite to well killing on July 9^th,with gas production of 3.09×10^5 m^3 in total,which is a world record with the longest continuous duration of gas production and maximal gas yield.This successful test brings a significant breakthrough on safety control of NGH production. | Jin-fa Li Jian-liang Ye Xu-wen Qin Hai-jun Qiu Neng-you Wu Hai-long Lu Wen-wei Xie Jing-an Lu Fei Peng Zhen-qiang Xu Cheng Lu Zeng-gui Kuang Jian-gong Wei Qian-yong Liang Hong-feng Lu Bei-bei Kou | 2018 | China Geology2018，1，1： | 117 |
| 2 | Evaluation of the Effects of Standard Rescue Procedure on Severe Trauma Treatment in China显示文摘 | Xiao-Feng Yin Tian-Bing Wang Pei-Xun Zhang Yu-Hui Kou Dian-Ying Zhang Kai Yu De-Cheng Lyu Mao-Zheng Liu Dong-Sheng Zhou Peng Zhang Jue-Hua Jing Wei-Wei Ge Li-Ying Cao Guo-Sheng Wang Shao-Jie Deng Weng-Hua Liu Mao Zhang Yong-An Xu Kun Zhang Bing Li Wei Wang Zhong-Li Gao Cheng-La Yi Bao-Guo Jiang | 2015 | Chinese Medical Journal2015，，10： | 18 |
| 3 | Genesis of the Wulong gold deposit,Liaoning Province,NE China:Constrains from noble gases,radiogenic and stable isotope studies显示文摘TheWulong lode deposit contains over 80 tonnes of gold with an average grade of 5.35 g/t.It is one of the largest deposits in Dandong City,Liaoning Province in northeast China.Previous studies on the deposit focused on its geological characteristics,geochemistry,fluid inclusions,and the timing of gold mineralization.However,controversy remains regarding the origin of the ore-forming fluids and metals,and the genesis of the gold deposit.This paper presents zircon UePb and pyrite RbeSr ages and S,Pb,He,and Ar isotopic results along with quartz H and O isotopic data for all litho-units associated with the deposit.Laser ablation inductively coupled mass spectrometry measurements yielded zircon UePb dates for samples of pre-mineralization rocks like granite porphyry dike,the Sanguliu granodiorite,fine-grained diorite,and syn-mineralization diorite,as well as post-mineralization dolerite,and lamprophyre;their emplacement ages are 1261 Ma,1241 Ma,1231 Ma,1201 Ma,1192 Ma,and 1152 Ma,respectively.The pyrite RbeSr isochron age is 1191 Ma,indicating that both magmatism and mineralization occurred during the Early Cretaceous.The d18OH2O values of ore-forming hydrothermal fluids from the quartzepolymetallic sulfide vein stage vary from 4.8&to 6.5&,and the dDV-SMOW values are between67.7&and75.9&,indicating that the ore-forming fluids were primarily magmatic.The noble gas isotope compositions of fluid inclusions hosted in pyrite suggest that the ore-forming fluids were dominantly derived from crustal sources with minor mantle input.Sulfur isotopic values of pyrite vary between 0.2&and 3.5&,suggesting that S was derived from a homogeneous magmatic source or possibly from fluids derived from the crust.The Pb isotopic compositions of sulfides(207Pb/204Pb?15.51 e15.71,206Pb/204Pb?17.35e18.75,208Pb/204Pb?38.27e40.03)indicate that the Pb of the Wulong gold deposit is a mixture of crust and mantle components.Geochronological and geochemical data,together with the regional geological history,indicate that Early Cretaceous magmatism and mineralization of the Wulong gold deposit occurred during the rollback of the subducting Paleo-Pacific Plate,which resulted in lithospheric thinning and the destruction of the North China Craton(NCC),which indicates that the deposit is of magmaticehydrothermal origin. | Peng Zhang Linlin Kou Yan Zhao Zhongwei Bi Deming Sha Renping Han Zhumin Li | 2020 | Geoscience Frontiers2020，11，2： | 13 |
| 4 | Molecular cloning, sequence analysis, and cadmium stress-rated expression changes of BTG1 in freshwater pearl mussel(Hyriopsis schlegelii)显示文摘The B cells translocation gene 1(BTG1) is a member of the BTG/TOB family of anti-proliferative genes,which have recently emerged as important regulators of cell growth and differentiation among vertebrates.Here,for the first time we cloned the full-length cDNA sequence of Hyriopsis schlegelii(Hs-BTG1),an economically important freshwater shellfish and potential indicator of environmental heavy metal pollution,for the first time.Using rapid amplification of cDNA ends(RACE) together with splicing the EST sequence from a haemocyte cDNA library,we found that Hs-BTG1 contains a 525 bp open reading frame(ORF) encoding a 174 amino-acid polypeptide,a 306 bp 5' untranslated region(5' UTR),and a 571 bp 3' UTR with a Poly(A) tail as well as a transcription termination signal(AATAAA).Homologue searching against GenBank revealed that Hs-BTG1 was closest to Crassostrea gigas BTG1,sharing 50.57% of protein identities.Hs-BTG1 also shares some typical features of the BTG/TOB family,possessing two well-conserved A and B boxes.Clustering analysis of Hs-BTG1 and other known BTGs showed that Hs-BTG1 was also closely related to BTG1 of C.gigas from the invertebrate BTG1 clade.Function prediction via homology modeling showed that both Hs-BTG1 and C.gigas BTG1 share a similar three-dimensional structure with Homo sapiens BTG1.Tissue-specific expression analysis of the Hs-BTG1 via real-time PCR showed that the transcripts were constitutively expressed,with the highest levels in the hepatopancreas and gills,and the lowest in both haemocyte and muscle tissue.Expression levels of Hs-BTG1 in hepatopancreas(2.03-fold),mantle(2.07-fold),kidney(2.2-fold) and haemocyte(2.5-fold) were enhanced by cadmium(Cd2+) stress,suggesting that Hs-BTG1 may have played a significant role in H.schlegelii adaptation to adverse environmental conditions. | Kou PENG Cheng-Yuan WANG Jun-Hua WANG Jun-Qing SHENG Jian-Wu SHI Jian LI Yi-Jiang HONG | 2014 | Zoological Research2014，35，5： | 7 |
| 5 | K-wire and tension band wire fixation in treating sternoclavicular joint dislocation显示文摘目的将评估可行性和由 K 电线和紧张乐队电线固定对待 sternoclavicular 关节脱臼的治疗学的效果,并且改进这种技术的安全和稳定性。这研究与平均数由 9 个盒子, 6 男性和 3 女性组成了的方法 25 年变老(范围, 9-62 年) 。原因是在 7 种情况中的交通事故,掉在在 1 种情况中的 1 种情况和战斗里。到操作的从损害的持续时间是到 7 天的 2 个小时。有 5 左脱臼和 4 正确脱臼;8 前面的脱臼和 1 以后的脱臼,包括一个与左 olecranon 骨折与左肩胛骨折和破裂结合了。用 K 电线和紧张乐队电线的开的减小和内部固定被执行对待脱臼。结果所有病人被跟随在上面为 6 ~ 24 个月, 10 个月平均。根据 Rockwood 手术后的 sternoclavicular 关节上的等级规模, 8 个盒子与 13.88 的一个平均分数完成了优秀结果,并且剩余的盒子与 12 的分数完成了好结果。解剖减小在所有情况中被获得。象严重感染没有如此的手术后的复杂并发症,对血容器和神经的损害,固定的失败,等等。病人们都对解剖减小和功能的恢复满意。K 电线和紧张乐队电线固定的技术是保险箱的结论,简单,有效,不太侵略并且成功地在矫形外科被使用了。它在尽管它有一些劣势,对待 sternoclavicular 关节脱臼是有效的。 | CHEN Qing-yu CHENG Shao-wen WANG Wei LIN Zhong-qin ZHANG Wei KOU Dong-quan SHEN Yue YING Xiao-zhou CHENG Xiao-jie LU Chuan-zhu PENG Lei | 2011 | Chinese Journal of Traumatology2011，14，1： | 7 |
| 6 | Phytochrome B interacts with SWC6 and ARP6 to regulate H2A.Z deposition and photomorphogensis in Arabidopsis显示文摘Light serves as a crucial environmental cue which modulates plant growth and development, and which is controlled by multiple photoreceptors including the primary red light photoreceptor,phytochrome B(phyB). The signaling mechanism of phyB involves direct interactions with a group of basic helix-loop-helix(bHLH) transcription factors, PHYTOCHROME-INTERACTING FACTORS(PIFs), and the negative regulators of photomorphogenesis, COP1 and SPAs. H2 A.Z is an evolutionarily conserved H2 A variant which plays essential roles in transcriptional regulation. The replacement of H2 A with H2 A.Z is catalyzed by the SWR1 complex. Here, we show that the Pfr form of phyB physically interacts with the SWR1 complex subunits SWC6 and ARP6. phyB and ARP6 coregulate numerous genes in the same direction,some of which are associated with auxin biosynthesis and response including YUC9, which encodes a rate-limiting enzyme in the tryptophandependent auxin biosynthesis pathway. Moreover,phyB and HY5/HYH act to inhibit hypocotyl elongation partially through repression of auxin biosynthesis. Based on our findings and previous studies, we propose that phyB promotes H2 A.Z deposition at YUC9 to inhibit its expression through direct phyB-SWC6/ARP6 interactions,leading to repression of auxin biosynthesis, and thus inhibition of hypocotyl elongation in red light. | Xuxu Wei Wanting Wang Peng Xu Wenxiu Wang Tongtong Guo Shuang Kou Minqing Liu Yake Niu Hong-Quan Yang Zhilei Mao | 2021 | Journal of Integrative Plant Biology2021，63，6： | 6 |
| 7 | Morphologic characteristics and growth interface stability of nano-micron FeS_2 whiskers显示文摘Micromorphology is further studied on the basis of our previous researches concerned with the nano-micron FeS2 whisker. There are obvious differences in the intensive degree, diameter and micromorphology among the FeS2 whiskers growing in different stages. From the early to late stage, the intensive degree increases, the diameter decreases, and the surface micro-morphology changes following the regularity: protrusive nodulation → coarse → smooth → flat. According to the theory of crystal growth, the geological setting and processes of whisker formation, we discuss the stability and evolution of crystal growth interface of FeS2 whisker occurring in Gengzhuang gold deposit (Shanxi Province, China). The results suggest that the negative temperature gradient and the supercooling appear in the early stage of the whisker growth, whereas the positive temperature gradient of reposeful state appears in the late stage. In the whisker growth stage, the component concentration changes through the three stages: severely nonhomogeneous in the early stage, relatively homogeneous in the middle stage, more homogeneous in the late stage. The general changing process of the interfacial state is from unstable to stable. Micromorphology of FeS2 whisker in Gengzhuang is the result of synergism of temperature, component concentration and stability of crystal interface phase in hydrothermal system. The micromorphology not only reflects the physical and chemical characteristics of the hydrothermal system during the whisker growth, but also indicates the stability characteristics of the interface phase and records the changing process of the whisker growth. | HUANG Fei WANG RuCheng ZHANG WenLan YAO YuZeng PENG YanDong KOU DaMing | 2009 | Chinese Science Bulletin2009，54，23： | 6 |
| 8 | Using the spike protein feature to predict infection risk and monitor the evolutionary dynamic of coronavirus显示文摘Background:Coronavirus can cross the species barrier and infect humans with a severe respiratory syndrome.SARS-CoV-2 with potential origin of bat is still circulating in China.In this study,a prediction model is proposed to evaluate the infection risk of non-human-origin coronavirus for early warning.Methods:The spike protein sequences of 2666 coronaviruses were collected from 2019 Novel Coronavirus Resource(2019nCoVR)Database of China National Genomics Data Center on Jan 29,2020.A total of 507 human-origin viruses were regarded as positive samples,whereas 2159 non-human-origin viruses were regarded as negative.To capture the key information of the spike protein,three feature encoding algorithms(amino acid composition,AAC;parallel correlation-based pseudo-amino-acid composition,PC-PseAAC and G-gap dipeptide composition,GGAP)were used to train 41 random forest models.The optimal feature with the best performance was identified by the multidimensional scaling method,which was used to explore the pattern of human coronavirus.Results:The 10-fold cross-validation results showed that well performance was achieved with the use of the GGAP(g=3)feature.The predictive model achieved the maximum ACC of 98.18%coupled with the Matthews correlation coefficient(MCC)of 0.9638.Seven clusters for human coronaviruses(229E,NL63,OC43,HKU1,MERS-CoV,SARS-CoV,and SARS-CoV-2)were found.The cluster for SARS-CoV-2 was very close to that for SARS-CoV,which suggests that both of viruses have the same human receptor(angiotensin converting enzyme II).The big gap in the distance curve suggests that the origin of SARS-CoV-2 is not clear and further surveillance in the field should be made continuously.The smooth distance curve for SARS-CoV suggests that its close relatives still exist in nature and public health is challenged as usual.Conclusions:The optimal feature(GGAP,g=3)performed well in terms of predicting infection risk and could be used to explore the evolutionary dynamic in a simple,fast and large-scale manner.The study may be beneficial for the surveillance of the genome mutation of coronavirus in the field. | Xiao-Li Qiang Peng Xu Gang Fang Wen-Bin Liu Zheng Kou | 2020 | Infectious Diseases of Poverty2020，9，2： | 6 |
| 9 | Sirolimus as primary immunosuppressant for calcineurin inhibitor-related renal insufficiency after liver transplantation显示文摘BACKGROUND:Calcineurin inhibitor-related renal toxicity affects patient and graft survival in transplant recipients. This study aimed to determine whether sirolimus is effective and safe in treating renal insufficiency related to tacrolimus after liver transplantation. METHODS:Tacrolimus for primary immunosuppression was used in 16 patients after liver transplantation. Patients with a creatinine level higher than 132.6 μmol/L were eligible for conversion to sirolimus. Simultaneously,the dose of tacrolimus was decreased to half. Blood urea nitrogen,creatinine,tacrolimus level,liver function and rejection episodes were monitored dynamically. RESULTS:All patients showed improvement of renal function after conversion to sirolimus. Blood creatinine level was reduced from 146.8±92.4 to 105.3±71.3 μmol/L(P<0.05). One patient had an acute rejection episode that was successfully treated with pulsed corticosteroids and low-dose tacrolimus. The side-effects of sirolimus included hyperlipidemia(4 patients) and leukocytopenia(2). CONCLUSION:Sirolimus can be safely used in liver transplant recipients suffering from tacrolimus-related renal insufficiency. | Yang, Yong-Jiu Li, Li-Xin He, Qiang Fan, Hua Jin, Zhong-Kui Lang, Ren Kou, Jian-Tao Li, Peng Xie, De-Hong Chen, Da-Zhi | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，4： | 5 |
| 10 | Precise temporal regulation of Dux is important for embryo development显示文摘Dear Editor,Zygotic genome activation(ZGA)following fertilization is accomplished through a process termed the maternal-to-zygotic transition,during which the maternal RNAs and proteins are degraded and zygotic genome is transcriptionally activated.In mice,minor ZGA occurs from S phase of the zygote to G1 phase of the two-cell(2C)embryo,while major ZGA takes place during the middle-to-late 2C stage with a burst of transcription of totipotent cleavage stage-specific genes and retrotransposons. | Mingyue Guo Yanping Zhang Jianfeng Zhou Yan Bi Junqin Xu Ce Xu Xiaochen Kou Yanhong Zhao Yanhe Li Zhifen Tu Kuisheng Liu Jiaming Lin Peng Yang Shaorong Gao Yixuan Wang | 2019 | Cell Research2019，29，11： | 5 |
| 11 | Intramedullary nailing of clavicular midshaft fractures in adults using titanium elastic nail显示文摘ObjectiveStudies 证明代替的 midclavicular 破裂的钉的有弹性的稳定的 intramedullary (ESIN ) 有优秀结果,以及高复杂并发症率和特定的问题。目的 fractures.MethodsTotally 是讨论 midshaft 的 ESIN 锁骨的 60 个合格病人(年老的 18-63 年) 被使随机化到在 2007 年 1 月和 2008 年 5 月之间的 ESIN 组或非起作用的组。锁骨的弄短在损伤和骨状的巩固以后被测量。X 光线照相术的联合和复杂并发症被估计。包括经常的肩膀分数和手臂,肩膀和手(破折号) 的残疾的功能分析得分在 15 月的 follow-up.ResultsESIN 导致了一 signifcantly 更短的时间到联合以后,被执行,特别为简单破裂。在 ESIN 组,所有病人得到了骨折联合, 5 个盒子有中间的皮激怒,因为, 1 个病人需要修订外科植入失败。在 nonoperative 组,有 3 个不属于工会的盒子, 2 征兆的 malunions 发展了要求校正截骨术。在在 intramedullary 稳定以后的 15 个月,在 ESIN 组的病人是对肩膀和全面结果的外观满意的更多,并且他们从 traumatic 以后的大改进有益于很多锁骨的弄短。而且,破折号分数更低,经常的分数与非起作用的 group.ConclusionESIN 相对照是显著地更高的是有更低的复杂并发症率,到每日的活动的更快的回来,优秀化妆品和更好功能的结果的一种安全最低限度地侵略的外科的技术,为对待中间柄的锁骨的破裂的锁骨的长度的恢复,导致高全面的满足,它能作为板固定或 mid-shaf 的 nonoperative | CHEN Qing-yu KOU Dong-quan CHENG Xiao-jie ZHANG Wei WANG Wei LIN Zhang-qin CHENG Shao-wen SHEN Yue YING Xiao-zhou PENG Lei LU Chuan-zhu | 2011 | Chinese Journal of Traumatology2011，14，5： | 4 |
| 12 | Experimental Study on New Multi-Column Tension-Leg-Type Floating Wind Turbine显示文摘Deep-water regions often have winds favorable for offshore wind turbines, and floating turbines currently show the greatest potential to exploit such winds. This work established proper scaling laws for model tests, which were then implemented in the construction of a model wind turbine with optimally designed blades. The aerodynamic,hydrodynamic, and elastic characteristics of the proposed new multi-column tension-leg-type floating wind turbine(Wind Star TLP system) were explored in the wave tank testing of a 1:50 scale model at the State Key Laboratory of Ocean Engineering at Shanghai Jiao Tong University. Tests were conducted under conditions of still water, white noise waves, irregular waves, and combined wind, wave, and current loads. The results established the natural periods of the motion, damping, motion response amplitude operators, and tendon tensions of the Wind Star TLP system under different environmental conditions, and thus could serve as a reference for further research. | ZHAO Yong-sheng SHE Xiao-he HE Yan-ping YANG Jian-min PENG Tao KOU Yu-feng | 2018 | China Ocean Engineering2018，32，2： | 4 |
| 13 | Assessment of the Biospheric Contribution to Surface Atmospheric CO_2 Concentrations over East Asia with a Regional Chemical Transport Model显示文摘A regional chemical transport model, RAMS-CMAQ, was employed to assess the impacts of biosphere–atmosphere CO2 exchange on seasonal variations in atmospheric CO2 concentrations over East Asia. Simulated CO2 concentrations were compared with observations at 12 surface stations and the comparison showed they were generally in good agreement. Both observations and simulations suggested that surface CO2 over East Asia features a summertime trough due to biospheric absorption, while in some urban areas surface CO2 has a distinct summer peak, which could be attributed to the strong impact from anthropogenic emissions. Analysis of the model results indicated that biospheric fluxes and fossil-fuel emissions are comparably important in shaping spatial distributions of CO2 near the surface over East Asia. Biospheric flux plays an important role in the prevailing spatial pattern of CO2 enhancement and reduction on the synoptic scale due to the strong seasonality of biospheric CO2 flux. The elevation of CO2 levels by the biosphere during winter was found to be larger than 5ppm in North China and Southeast China, and during summertime a significant depletion( 7 ppm) occurred in most areas,except for the Indo-China Peninsula where positive bioflux values were found. | KOU Xingxia ZHANG Meigen PENG Zhen WANG Yinghong | 2015 | Advances in Atmospheric Sciences2015，32，3： | 4 |
| 14 | Effect of calcium citrate on bone integration in a rabbit femur defect model显示文摘Objective:To explore effect of calcium citrate on bone integration in a rabbit femur defect model, and to compare the bone formation with different sizes by radiological and histological study. Methods:Twenty-four male Japanese white rabbits were randomly divided into three groups (Group A.B.C)in this study.Under anesthesia,defects of four sizes(1.2,1.5,2.0 and 2.5 mm) were created in each of the rabbits.Commercially pure calcium citrate powder was placed inside the medullary compartment of the femur(Experimental),while in the contralateral femur(Control) nothing was implanted.The defects were analyzed using radiography and histological analysis by using Imagepro-Plus 6.0 software after animal was sacrificed at 4th(Group A),6th(Group B) and 8th(Group C) weeks postoperatively.Four samples were analyzed for each size of defect and each healing period.Results:The histological and the radiologic evaluation were performed after sacrification of all rabbits on postoperative 4th and 6th weeks,It showed significant difference between the experimental group and the control group when these defects were less than or equal to 2.0 mm.No statistical difference was observed when these defects were larger than 2.0 mm at all healing periods except at the 4th week.Conclusions:Calcium citrate affects the early periods of hone defects healing mechanism in Japanese white rabbits positively,especially when the defect is not too large,We suggest further studies on calcium citrate to determine the effects of various dosages,administration ways and the experimental time on the bone defects. | Wei Zhang Wei Wang Qing-Yu Chen Zhong-Qin Lin Shao-Wen Cheng Dong-Quan Kou Xiao-Zhou Ying Yue Shen Xiao-Jie Cheng Peng-Fei Nie Xiu-Cui Li Ferdinand An Rompis Hang Huang Hua Zhang Zhong-Lin Mu Lei Peng | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，4： | 3 |
| 15 | Transarterial chemoembolization with hepatic arterial infusion chemotherapy plus S-1 for hepatocellular carcinoma显示文摘BACKGROUND Transarterial chemoembolization(TACE)and hepatic arterial infusion chemotherapy(HAIC)have shown promising local benefits for advanced hepatocellular carcinoma(HCC).S-1,a composite preparation of a 5-fluorouracil prodrug,has proven to be a convenient oral chemotherapeutic agent with definite efficacy against advanced HCC.AIM To evaluate the efficacy and safety of TACE followed by HAIC with or without oral S-1 for treating advanced HCC.METHODS In this single-center,open-label,prospective,randomized controlled trial,117 participants with advanced HCC were randomized to receive TACE followed by oxaliplatin-based HAIC either with(TACE/HAIC+S-1,n=56)or without(TACE/HAIC,n=61)oral S-1 between December 2013 and September 2017.Two participants were excluded from final analysis for withdrawing consent.The primary endpoint was progression-free survival(PFS)and secondary endpoints included overall survival(OS),objective response rate,disease control rate and safety.RESULTS In total,115 participants(100 males and 15 females;mean age,57.7 years±11.9)were analyzed.The median PFS and OS were 5.0 mo(0.4–58.6 mo)(95%confidence interval(CI):3.82 to 6.18)vs 4.4 mo(1.1–54.4 mo)(95%CI:2.54 to 6.26;P=0.585)and 8.4 mo(0.4–58.6 mo)(95%CI:6.88 to 9.92)vs 8.3 mo(1.4–54.4 m)(95%CI:5.71 to 10.96;P=0.985)in the TACE/HAIC+S-1 and TACE/HAIC groups,respectively.The objective response rate and disease control rate were 30.9%vs 18.4%and 72.7%vs 56.7%in the TACE/HAIC+S-1 and TACE/HAIC groups,respectively.Grade 3/4 adverse events had a similar frequency in both treatment groups.CONCLUSION No improvements in tumor response rates,PFS or OS were observed with the addition of S-1 to TACE/HAIC in advanced HCC.Both treatment regimens had a similar safety profile. | Jian-Hai Guo Shao-Xing Liu Song Gao Fu-Xin Kou Xin Zhang Di Wu Xiao-Ting Li Hui Chen Xiao-Dong Wang Peng Liu Peng-Jun Zhang Hai-Feng Xu Guang Cao Lin-Zhong Zhu Ren-Jie Yang Xu Zhu | 2020 | World Journal of Gastroenterology2020，26，27： | 3 |
| 16 | Numerical Simulation of CO_2 Concentrations in East Asia with RAMS-CMAQ显示文摘The regional air quality modeling system RAMS-CMAQ(Regional Atmospheric Modeling System and Models-3 Community Multi-scale Air Quality) was developed by incorporating a vegetation photosynthesis and respiration module(VPRM) and used to simulate temporal-spatial variations in atmospheric CO2 concentrations in East Asia,with prescribed surface CO2 fluxes(i.e.,fossil fuel emission,biomass burning,sea-air CO2 exchange,and terrestrial biosphere CO2 flux).Comparison of modeled CO2 mixing ratios with eight ground-based in-situ measurements demonstrated that the model was able to capture most observed CO2 temporal-spatial features.Simulated CO2 concentrations were generally in good agreement with observed concentrations.Results indicated that the accumulated impacts of anthropogenic emissions contributed more to increased CO2 concentrations in urban regions relative to remote locations.Moreover,RAMS-CMAQ analysis demonstrates that surface CO2 concentrations in East Asia are strongly influenced by terrestrial ecosystems. | KOU Xing-Xia ZHANG Mei-Gen PENG Zhen | 2013 | Atmospheric and Oceanic Science Letters2013，6，4： | 2 |
| 17 | Effect of cross-flow direction of coolant on film cooling effectiveness with one inlet and double outlet hole injection显示文摘In order to study the effect of cross-flow directions of an internal coolant on film cooling performance,the discharge coefficients and film cooling effectiveness with one inlet and double outlet hole injections were simulated.The numerical results show that two different cross-flow directions of the coolant cause the same decrease in the discharge coefficients as that in the case of supplying coolant by a plenum.The different proportion of the mass flow out of the two outlets of the film hole results in different values of the film cooling effectiveness for three different cases of coolant supplies.The film cooling effectiveness is the highest for the case of supplying coolant by the plenum.At a lower blowing ratio of 1.0,the film cooling effectiveness with coolant injection from the right entrance of the passage is higher than that from the left entrance of the passage.At a higher blowing ratio of 2.0,the opposite result is found. | Guangchao Lin Chaolin Wu Wei Zhang Zhihai Kou Dawei Peng | 2012 | Propulsion and Power Research2012，1，1： | 2 |
| 18 | Osteogenic capability of autologous rabbit adipose-derived stromal cells in repairing calvarial defects显示文摘ObjectiveTo 评估在里面 vitro 并且在脂肪质导出 stromal 房间(ASC ) 的 vivo osteogenic 能力, .MethodASCs 从新西兰白兔子被孤立并且由染色的碱的磷酸酶(高山) 决定了, von Kossa 染色并且茜素红染色。osteogenic 区别的一些特定的标记包括高山, osteocalcin (OCN ) , osteopontin (OPN ) 被反向的抄写聚合酶链反应(RT-PCR ) 检验。在 vivo, demineralized 骨头矩阵(DBM )-ASCs composites 被植入进在纵的中线的每个方面创造的兔子 calvarial 缺点。在 6 个星期以后, transplants 的 histo 逻辑性质是 analyzed.ResultsASCs 成功地被导致进成骨。染色的高山, von Kossa 染色和茜素红染色显示出积极结果。高山, OCN 和 OPN 的表情在 osteogenic 媒介在耕作以后在 ASC 被检测。广泛的新骨头在与 DBM-ASCs composites.ConclusionASCs 移植的缺点被观察有潜力区分进 osteogenic 系和 DBM-ASCs 构造是为在骨头缺点的新生的一个有希望的方法。 | CHENG Shao-wen LIN Zhong-qin WANG Wei ZHANG Wei KOU Dong-quan YING Xiao-zhou CHEN Qing-yu SHEN Yue CHENG Xiao-jie PENG Lei LU Chuan-zhu | 2011 | Chinese Journal of Traumatology2011，14，5： | 2 |
| 19 | Nano-polycrystalline diamond formation under ultra-high pressure显示文摘 | Chao Xu Duanwei He Haikuo Wang Junwei Guan Chunmei Liu Fang Peng Wendan Wang Zili Kou Kai He Xiaozhi Yan Yan Bi Lei Liu Fengjiao Li Bo Hui | 2013 | International Journal of Refractory Metals and Hard Materials2013，，： | 2 |
| 20 | Accounting for CO2 Variability over East Asia with a Regional Joint Inversion System and Its Preliminary Evaluation显示文摘A regional surface carbon dioxide(CO_2) flux inversion system, the Tan-Tracker-Region, was developed by incorporating an assimilation scheme into the Community Multiscale Air Quality(CMAQ) regional chemical transport model to resolve fine-scale CO_2 variability over East Asia. The proper orthogonal decomposition-based ensemble four-dimensional variational data assimilation approach(POD-4 DVar) is the core algorithm for the joint assimilation framework, and simultaneous assimilations of CO_2 concentrations and surface CO_2 fluxes are applied to help reduce the uncertainty in initial CO_2 concentrations. A persistence dynamical model was developed to describe the evolution of the surface CO_2 fluxes and help avoid the 'signal-to-noise' problem; thus, CO_2 fluxes could be estimated as a whole at the model grid scale, with better use of observation information. The performance of the regional inversion system was evaluated through a group of single-observation-based observing system simulation experiments(OSSEs). The results of the experiments suggest that a reliable performance of Tan-Tracker-Region is dependent on certain assimilation parameter choices, for example, an optimized window length of approximately 3 h, an ensemble size of approximately 100, and a covariance localization radius of approximately 320 km. This is probably due to the strong diurnal variation and spatial heterogeneity in the fine-scale CMAQ simulation, which could affect the performance of the regional inversion system. In addition, because all observations can be artificially obtained in OSSEs, the performance of Tan-Tracker-Region was further evaluated through different densities of the artificial observation network in different CO_2 flux situations. The results indicate that more observation sites would be useful to systematically improve the estimation of CO_2 concentration and flux in large areas over the model domain. The work presented here forms a foundation for future research in which a thorough estimation of CO_2 flux variability over East Asia could be performed with the regional inversion system. | xingxia kou xiangjun tian meigen zhang zhen peng xiaoling zhang | 2017 | Journal of Meteorological Research2017，31，5： | 2 |
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