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| 1 | Behavior of composite rigid frame bridge under bi-directional seismic excitations显示文摘Pushover analysis and time history analysis are conducted to explore the bi-directional seismic behavior of composite steel-concrete rigid frame bridge,which is composed of RC piers and steel-concrete composite girders.Both longitudinal and transverse directions excitations are investigated using OpenSees.Firstly,the applicability of pushover analysis based on the fundamental mode is discussed.Secondly,an improved pushover analysis method considering the contribution of higher modes is proposed,and the applicability on composite rigid frame bridges under bi-directional earthquake is verified.Based on this method,an approach to predict the displacement responses of composite rigid frame bridge under random bi-directional seismic excitations by revising the elasto-plastic demand curve is also proposed.It is observed that the developed method yield a good estimate on the responses of composite rigid frame bridges under bi-directional seismic excitations. | Xiaogang Liu Jiansheng Fan Jianguo Nie Guo Li | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014，1，1： | 22 |
| 2 | Study on Multiplexing Ability of Identical Fiber Bragg Gratings in a Single Fiber显示文摘一个新奇 multiplexing 纤维布拉格栅栏(FBG ) 的 multiplexing 能力方法基于光时间领域 Reflecto 米(OTDR ) 和时间部门 Multiplexing TDM 技术是理论上分析了并且学习。这个方法在单个纤维与低反射率允许几百相同 FBG 的讯问,处于监视工程的太空健康使 FBG 传感器更适用。如果 FBG 反射率是足够地低的,分析证明 multiplexing 能力能极大地被改进。并且因此,一个便宜大规模分布式的察觉到系统能基于这个方法被认识到。当评估这个系统的 multiplexing 能力时,我们第一次建议在 FBG 之中的多思考的干扰效果应该被考虑。 | LIU Jiansheng ZHANG Jing LI Xin ZHENG Zheng | 2011 | Chinese Journal of Aeronautics2011，24，5： | 12 |
| 3 | Chemical and Isotopic Approach to Groundwater Cycle in Western Qaidam Basin,China显示文摘Due to the extremely arid climate in the western Qaidam Basin,the groundwater almost becomes the single water source for local residents and industrial production.It is necessary to know the reliable information on the groundwater cycle in this region for reasonable and sustainable exploitation of the groundwater resources with the further execution of recycling economy policies.This study focused on the recharge,the flow rate and the discharge of groundwater in the western Qaidam Basin through investigations on water chemistry and isotopes.Hydrological,chemical and isotopic characteristics show that the groundwater in the western Qaidam Basin was recharged by meltwater from new surface snow and old bottom glaciers on the northern slope of the Kunlun Mountains.In addition,the results also prove that the source water is enough and stable,and the rates of the circulation and renewal of the groundwater are relatively quick.Therefore,it can be concluded that the groundwater resources would guarantee the regional requirement if the meltwater volume of the mountains has not a great changes in future,moreover,water exploitation should be limited to the renewable amount of the groundwater reservoir in the western Qaidam Basin. | TAN Hongbing RAO Wenbo CHEN Jiansheng SU Zhiguo SUN Xiaoxu LIU Xiaoyan | 2009 | Chinese Geographical Science2009，19，4： | 10 |
| 4 | Reuse of Fenton sludge as an iron source for NiFe_2O_4 synthesis and its application in the Fenton-based process显示文摘The potentially hazardous iron-containing sludge from the Fenton process requires proper treatment and disposal, which often results in high treatment cost. In this study, a novel method for the reuse of Fenton sludge as an iron source for the synthesis of nickel ferrite particles(NiFe_2O_4) is proposed. Through a co-precipitation method followed by sintering at 800°C, magnetic NiFe_2O_4 particles were successfully synthesized, which was confirmed by powder X-ray diffraction(XRD), scanning electronic microscopy(SEM), energy dispersive spectroscopy(EDS), Fourier transform infrared spectroscopy(FT-IR) and Raman spectroscopy. The synthesized NiFe_2O_4 could be used as an efficient catalyst in the heterogeneous Fenton process. In phenol degradation with H_2O_2 or NiFe_2O_4 alone, the phenol removal efficiencies within the reaction time of 330 min were as low as 5.9% ± 0.1% and 13.5% ±0.4%, respectively. However, in the presence of both NiFe_2O_4 and H_2O_2, phenol removal efficiency as high as 95% ± 3.4% could be achieved, indicating the excellent catalytic performance of NiFe_2O_4 in the heterogeneous Fenton process. Notably, a rapid electron exchange between_Ni II and_Fe III ions in the NiFe_2O_4 structure could be beneficial for the Fenton reaction. In addition, the magnetic catalyst was relatively stable, highly active and recoverable, and has potential applications in the Fenton process for organic pollutant removal. | Hui Zhang Jianguo Liu Changjin Ou Faheem Jinyou Shen Hongxia Yu Zhenhuan Jiao Weiqing Han Xiuyun Sun Jiansheng Li Lianjun Wang | 2017 | Journal of Environmental Sciences2017，29，3： | 10 |
| 5 | RESEARCH ON THE ENERGY ECONOMIZATION OF ELECTRO-HYDRAULIC HAMMER显示文摘The research on the driving principle and economization of energy of electro-hydraulic hammer is discussed. By means of the balance chart of energy, the method and formulas to calculate every level efficiency and the total efficiency of steam drived hammer are formed.With the aid of actual data of plants,the actual efficiency of steam drived hammer is got. The working principle and the driving system of electro-hydraulic hammer are introduced. The procedure of energy energy of this hammer is analyzed. The utilization ratio of energy of this type of hammer is got. It is shown that the efficiency of electro-hydraulic hammer is 7 times as much as that of steam drived hammer. | Lei Bufang Li Yongtang Liu Jiansheng (Department of Mechanical Engineering, Taiyuan Heavy Machinery Institute) | 2000 | Chinese Journal of Mechanical Engineering2000，13，1： | 10 |
| 6 | Quasi-variational principles of single flexible body dynamics and their applications显示文摘The reasons for studying single flexible body dynamics are that on one hand,it is the basis of flexible multi-body dynamics.If the theory of the single flexible body dynamics has been deeply studied,the theory of flexible multi-body dynamics will be researched easily.On the other hand,it has its unique and important applications.Quasi-variational principle of non-conservative single flexible body dynamics is established under the cross-link of particle rigid body mechanics and deformable body mechanics.Taking the interceptor as an example,this paper has explained the physical meaning of the quasi-stationary value condition of the quasi-variational principle in non-conservative single flexible body dynamics.Taking the launch of rocket as an example,it has illustrated the features of'one force for two effects'in a single flexible body dynamics.With an example of the extending flexible beam coupled with the spacecraft attitude,it has shown the transition from the single flexible body dynamics to the flexible multi-body dynamics.Finally,a number of related problems are discussed. | LIANG LiFu LIU ShiQuan ZHOU JianSheng | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，5： | 9 |
| 7 | Removal of phosphate from wastewater using alkaline residue显示文摘Alkaline residue(AR) was found to be an efficient adsorbent for phosphate removal from wastewater. The kinetic and equilibrium of phosphate removal were investigated to evaluate the performance of modified alkaline residue. After treatment by NaOH(AR-NaOH), removal performance was significantly improved, while removal performance was almost completely lost after treatment by HCl(AR-HCl). The kinetics of the removal process by all adsorbents was well characterized by the pseudo second-order model. The Langmuir model exhibited the best correlation for AR-HCl, while AR was effectively described by Freundlich model. Both models were well fitted to AR-NaOH. The maximum adsorption capacities calculated from Langmuir equation were in following manner: AR-NaOH > AR > AR-HCl. Phosphate removal by alkaline residue was pH dependent process. Mechanisms for phosphate removal mainly involved adsorption and precipitation, varied with equilibrium pH of solution. For AR-HCl, the acid equilibrium pH(< 6.0) was unfavorable for the formation of Ca-P precipitate, with adsorption as the key mechanism for phosphate removal. In contrast, for AR and ARNaOH, precipitation was the dominant mechanism for phosphate removal, due to the incrase on pH(> 8.0) after phosphate removal. The results of both XRD and SEM analysis confirmed CaHPO4·2H2O formation after phosphate removal by AR and AR-NaOH. | Yubo Yan Xiuyun Sun Fangbian Ma Jiansheng Li Jinyou Shen Weiqing Han Xiaodong Liu Lianjun Wang | 2014 | Journal of Environmental Sciences2014，26，5： | 8 |
| 8 | Simultaneous pyridine biodegradation and nitrogen removal in an aerobic granular system显示文摘Simultaneous pyridine biodegradation and nitrogen removal were successfully achieved in a sequencing batch reactor(SBR) based on aerobic granules. In a typical SBR cycle, nitritation occurred obviously after the majority of pyridine was removed, while denitrification occurred at early stage of the cycle when oxygen consumption was aggravated. The effect of several key operation parameters, i.e., air flow rate, influent NH_4^+-N concentration,influent p H and pyridine concentration, on nitritation, pyridine degradation and total nitrogen(TN) removal, was systematically investigated. The results indicated that high air flow rate had a positive effect on both pyridine degradation and nitritation but a negative impact of overhigh air flow rate. With the increase of NH_4^+ dosage, both nitritation and TN removal could be severely inhibited. Slightly alkaline condition, i.e., pH 7.0–8.0, was beneficial for both pyridine degradation and nitritation. High pyridine dosage often resulted in the delay of both pyridine degradation and nitritation. Besides, extracellular polymeric substances production was affected by air flow rate, NH_4^+ dosage, pyridine dosage and p H.In addition, high-throughput sequencing analysis demonstrated that Bdellovibrio and Paracoccus were the dominant species in the aerobic granulation system. Coexistence of pyridine degrader, nitrification related species, denitrification related species, polymeric substances producer and self-aggregation related species was also confirmed by highthroughput sequencing. | Xiaodong Liu Shijing Wu Dejin Zhang Jinyou Shen Weiqing Han Xiuyun Sun Jiansheng Li Lianjun Wang | 2018 | Journal of Environmental Sciences2018，30，5： | 7 |
| 9 | A User Differential Range Error Calculating Algorithm Based on Analytic Method显示文摘提高完整,有更少的执行时间的一个分析方法(AM ) 被建议计算微分范围错误(UDRE ) 由用户过去常检测潜在的风险的用户。位置推算历和钟修正计算方法首先被介绍。它证明计算 UDRE 的最重要的事情是在服务体积发现最糟的用户地点(WUL ) 。然后,用 AM 的一个 UDRE 算法被描述解决这个问题。由使用错误向量的协变性矩阵,寻找 WUL 被变换成一个分析几何学问题。WUL 的地点能被数学推导直接获得。实验被进行比较在建议 AM 算法和在主人车站使用的彻底的格子搜索(EGS ) 方法之间的表演。AM 算法的正确性能被 EGS 方法和 AM 算法证明的结果表演能在超过 90% 减少计算时间。这个建议算法的计算复杂性从而比 EGS. 的好这个算法对在主人车站计算 UDRE 更合适。 | SHAO Bo LIU Jiansheng ZHAO Ruibin HUANG Zhigang LI Rui | 2011 | Chinese Journal of Aeronautics2011，24，6： | 7 |
| 10 | Carbon-Selective Difluoromethylation of Soft Carbon Nucleophiles with Difluoromethylated Sulfonium Ylide显示文摘A highly carbon-selective difluoromethylation of soft carbon nucleophiles including ^-ketoesters, malonates, oxindoles, benzofuranones andketene silyl acetals with a difluoromethylated sulfonium ylide under mild conditions was described. Mechanistic studies suggest that these difluorometh-ylating reactions proceed via a difluorocarbene pathway. | Jiansheng Zhu Hanliang Zheng Xiao-Song Xue Yisa Xiao Yafei Liu Qilong Shen | 2018 | Chinese Journal of Chemistry2018，36，11： | 7 |
| 11 | Sparse Representation for Face Recognition Based on Constraint Sampling and Face Alignment显示文摘Sparse Representation based Classification (SRC) has emerged as a new paradigm for solving recognition problems. This paper presents a constraint sampling feature extraction method that improves the SRC recognition rate. The method combines texture and shape features to significantly improve the recognition rate. Tests show that the combined constraint sampling and facial alignment achieves very high recognition accuracy on both the AR face database (99.52%) and the CAS-PEAL face database (99.54%). | Jing Wang Guangda Su Ying Xiong Jiansheng Chen Yan Shang Jiongxin Liu Xiaolong Ren | 2013 | Tsinghua Science and Technology2013，18，1： | 6 |
| 12 | Dealing with the Spatial Synthetic Heterogeneity of Aquifers in the North China Plain:A Case Study of Luancheng County in Hebei Province显示文摘The complexity of alluvial-pluvial fan depositional systems makes the detailed characterization of their heterogeneity difficult,yet such a detailed characterization is commonly needed for construction of reliable groundwater models.Traditional models mainly focus on using a single aquifer property to qualitatively or semi-quantitatively characterize the heterogeneity of aquifer,so that they are unable to quantitatively reflect the synthetic heterogeneity of all aquifer properties.In this paper,we propose the heterogeneity synthetic index(HSI) for quantitative characterization of synthetic heterogeneity of an aquifer.The proposed calculation process involves four steps:(1) estimation of the hydraulic conductivity of a sediment sample using the cloud-Markov model,(2) establishment of the sedimentary microfacies distribution model through the Markov chain,(3) characterization of the distribution model of hydrogeological parameters using the improved sequential simulation method according to the 'facies-controlled modeling' technique,and(4) application of the entropy weight method to calculate the weight coefficient of the above aquifer properties.The HSI of an aquifer is calculated by superposition of these models according to the corresponding weight coefficient.This approach was applied to the Luancheng aquifer deposit in the southeast Hutuo River alluvial-pluvial fan in the North China Plain(NCP).The results have demonstrated that aquifer 3 which was formed in the middle Pleistocene has the strongest heterogeneity,with an HSI of 0.25-0.75.Aquifer 4 formed in the early Pleistocene shows an intermediate heterogeneity,with the HSI ranging 0.35-0.75.The weakest heterogeneity was found in aquifers 1 and 2 formed in the Holocene and late Pleistocene,with HSI values of 0.40-0.75 and 0.40-0.80,respectively.The heterogeneity of all the four aquifers is relatively strong in the radial direction of the Huai River alluvial-pluvial fan due to the abrupt change of microfacies.In contrast,in the radial direction of the Hutuo River alluvial-pluvial fan,the microfacies change mildly,and the continuity of hydrogeological parameters is better,which has resulted in weaker heterogeneity of the four aquifers in this direction.Findings suggest that the sedimentary environment has significant effects on the aquifer heterogeneity.Considering that there are many aquifer properties,HSI can quantitatively characterize the synthetic heterogeneity of the aquifer and describe the influence of each aquifer property on the synthetic heterogeneity of the aquifer according to its weight coefficient.Thus the HSI approach can be successfully used to deal with the spatial heterogeneity of aquifer and provide a foundation for studies on contaminant transport. | MA Rong SHI Jiansheng LIU Jichao | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 6 |
| 13 | Change of Soil Organic Carbon after Cropland Afforestation in ′Beijing-Tianjin Sandstorm Source Control′ Program Area in China显示文摘Land use change is one of the major factors that affect soil organic carbon(SOC) variation and global carbon balance. However, the effects of land use change on SOC are always variable. In this study, using a series of paired-field experiments, we estimated the effects of revegetation types and environmental conditions on SOC stock and vertical distribution after replacement of cropland with poplar(Populus tomentosa) and korshinsk peashrub(Caragana korshinskii) in three climate regions(Chifeng City, Fengning City and Datong City of the ′Beijing-Tianjin Sandstorm Source Control′(BTSSC) program area. The results show that SOC sequestration rate ranges from 0.15 Mg/(ha·yr) to 3.76 Mg/(ha·yr) in the soil layer of 0–100 cm in early stage after cropland afforestation in the BTSSC program area. The SOC accumulation rates are the highest in Fengning for both the two vegetation types. Compared to C. korshinskii, P. tomentosa has greater effects on SOC accumulation in the three climate regions, but significantly greater effect only appears in Datong. The SOC density increases by 20%–111% and 15%–59% for P. tomentosa and 9%–63% and 0–73% for C. korshinskii in the 0–20 cm and 20–100 cm soil layers, respectively. Our results indicate that cropland afforestation not only affects SOC stock in the topsoil, but also has some effects on subsoil carbon. However, the effect of cropland afforestation on SOC accumulation varied with climate regions and revegetation types. Considering the large area of revegetation and relatively high SOC accumulation rate, SOC sequestration in the BTSSC program should contribute significantly to decrease the CO2 concentration in the atmosphere. | ZENG Xinhua ZHANG Wanjun LIU Xiuping CAO Jiansheng SHEN Huitao ZHAO Xin ZHANG Nan-nan BAI Yuru Yi Mei | 2014 | Chinese Geographical Science2014，24，4： | 6 |
| 14 | Characteristics and hazards of different snow avalanche types in a continental snow climate region in the Central Tianshan Mountains显示文摘Snow avalanches are a common natural hazard in many countries with seasonally snow-covered mountains.The avalanche hazard varies with snow avalanche type in different snow climate regions and at different times.The ability to understand the characteristics of avalanche activity and hazards of different snow avalanche types is a prerequisite for improving avalanche disaster management in the mid-altitude region of the Central Tianshan Mountains.In this study,we collected data related to avalanche,snowpack,and meteorology during four snow seasons(from 2015 to 2019),and analysed the characteristics and hazards of different types of avalanches.The snow climate of the mid-altitude region of the Central Tianshan Mountains was examined using a snow climate classification scheme,and the results showed that the mountain range has a continental snow climate.To quantify the hazards of different types of avalanches and describe their situation over time in the continental snow climate region,this study used the avalanche hazard degree to assess the hazards of four types of avalanches,i.e.,full-depth dry snow avalanches,full-depth wet snow avalanches,surface-layer dry snow avalanches,and surface-layer wet snow avalanches.The results indicated that surface-layer dry snow avalanches were characterized by large sizes and high release frequencies,which made them having the highest avalanche hazard degree in the Central Tianshan Mountains with a continental snow climate.The overall avalanche hazard showed a single peak pattern over time during the snow season,and the greatest hazard occurred in the second half of February when the snowpack was deep and the temperature increased.This study can help the disaster and emergency management departments rationally arrange avalanche relief resources and develop avalanche prevention strategies. | HAO Jiansheng Richard MIND'JE LIU Yang HUANG Farong ZHOU Hao LI Lanhai | 2021 | Journal of Arid Land2021，13，4： | 5 |
| 15 | A comparative study of the characteristics of two Coxsackie A virus type 16 strains (genotype B)显示文摘Coxsackie A virus is one of the major pathogens associated with hand, foot and mouth disease (HFMD). The etiological characteristics of Coxsackie A virus type 16 (CA16) are thought to correlate with the pathological process of its infection. Two CA16 strains that were isolated from a severe HFMD patient presented with different plaque forms. This observation, along with biological analysis, indicated that the differences in the strains' biological characteristics, such as proliferation kinetics and immunogenicity, correlate with differences in their pathogenicity toward neonatal mice. Furthermore, these differences are thought to be associated with the sequence of the 5′ non-coding region of the viral genome and the VP1 structural region sequence. The results suggest that the biological and genetic characteristics of the CA16 viral strains are relevant to their pathogenicity. | YANG ErXia ZHAO Heng ZHANG Ying LIU JianSheng LIAO Yun WANG LiChun CUI PingFang YANG LiXian LIU LongDing DONG ChengHong DONG ShaoZhong SHAO CongWen JIANG Li SUN Le LI QiHan | 2012 | Science China(Life Sciences)2012，55，4： | 5 |
| 16 | Conditional QTL mapping of three yield components in common wheat(Triticum aestivum L.)显示文摘Spike number per m^2(SN),kernel number per spike(KNPS) and thousand-kernel weight(TKW)are the three main components determining wheat(Triticum aestivum L.) yield.To evaluate the relationships among them a doubled haploid(DH) population consisting of 168 lines grown at three locations for three years was analyzed by unconditional and conditional QTL mapping.Thirty-three unconditional QTL and fifty-nine conditional QTL were detected.Among them,two QTL(QSN-DH-2B and QSN-DH-3A-1.1) improved SN,with no effect on KNPS.QKNPS-DH-2B-2.1 improved KNPS,with no effect on SN.QKNPS-DH-1A-1.1,QKNPS-DH-2D-1.1and QKNPS-DH-6A improved KNPS,with no effect on SN or TKW.QKNPS-DH-6B was associated with increased SN and TKW.In addition,QTKW-DH-4B,QTKW-DH-5B and QTKW-DH-7B increased TKW without decreasing KNPS.These results provide useful information for marker assisted selection(MAS) and improvement in wheat yield. | Han Zhang Jiansheng Chen Ruyu Li Zhiying Deng Kunpu Zhang Bin Liu Jichun Tian | 2016 | The Crop Journal2016，4，3： | 5 |
| 17 | A Utility-Based Buffer Management Policy for Improving Data Dissemination in Opportunistic Networks显示文摘In opportunistic networks, most existing buffer management policies including scheduling and passive dropping policies are mainly for routing protocols. In this paper, we proposed a Utility-based Buffer Management strategy(UBM) for data dissemination in opportunistic networks. In UBM, we first design a method of computing the utility values of caching messages according to the interest of nodes and the delivery probability of messages, and then propose an overall buffer management policy based on the utility. UBM driven by receivers completely implements not only caching policies, passive and proactive dropping policies, but also scheduling policies of senders. Simulation results show that, compared with some classical dropping strategies, UBM can obtain higher delivery ratio and lower delay latency by using smaller network cost. | Jiansheng Yao Chunguang Ma Haitao Yu Yanling Liu Qi Yuan | 2017 | China Communications2017，14，7： | 5 |
| 18 | Analysis of Frequency Characteristics and Sensitivity of Compliant Mechanisms显示文摘Based on a modified pseudo-rigid-body model,the frequency characteristics and sensitivity of the large-deformation compliant mechanism are studied.Firstly,the pseudo-rigid-body model under the static and kinetic conditions is modified to enable the modified pseudo-rigid-body model to be more suitable for the dynamic analysis of the compliant mechanism.Subsequently,based on the modified pseudo-rigid-body model,the dynamic equations of the ordinary compliant four-bar mechanism are established using the analytical mechanics.Finally,in combination with the finite element analysis software ANSYS,the frequency characteristics and sensitivity of the compliant mechanism are analyzed by taking the compliant parallel-guiding mechanism and the compliant bistable mechanism as examples.From the simulation results,the dynamic characteristics of compliant mechanism are relatively sensitive to the structure size,section parameter,and characteristic parameter of material on mechanisms.The results could provide great theoretical significance and application values for the structural optimization of compliant mechanisms,the improvement of their dynamic properties and the expansion of their application range. | LIU Shanzeng DAI Jiansheng LI Aimin SUN Zhaopeng FENG Shizhe CAO Guohua | 2016 | Chinese Journal of Mechanical Engineering2016，29，4： | 5 |
| 19 | Study on the mechanism of isotope fractionation in soil water during the evaporation process under equilibrium condition显示文摘In this study, with the method of vacuum extraction, two evaporative processes of soil water and free water under equilibrium condition were simulated. For each sample,water vapor was condensed by liquid nitrogen and was collected in four time intervals. From the analysis of hydrogen and oxygen isotopic compositions of the water collected at different times, it was discovered that the isotope fractionation of soil water also follows the mode, which is just the same as the evaporative process of free water. The relationship between the stable hydrogen and oxygen isotopes in residual water showed that the simulative evaporation line was close to the global meteoric water line (GMWL) under the equilibrium condition at about 20℃. Comparison of the two types of evaporative processes indicated that the isotope fractionation and evaporation velocity of soil water were only slightly modified by the Van der Waals force. | SUN Xiaoxu CHEN Jiansheng TAN Hongbing RAO Wenbo WANG Yongsen LIU Xiaoyan SU Zhiguo | 2009 | Chinese Journal Of Geochemistry2009，28，4： | 4 |
| 20 | Three Tiaobu Feishen therapies protect human alveolar epithelial cells against cigarette smoking and tumor necrosis factor-mlear factor-kappa B pathwayα-induced inflamation by nuc显示文摘OBJECTIVE: To investigate the efficacy of Tiaobu Feishen formulae(TBFS), including Bufei Jianpi formula(BJF), Bufei Yishen formula(BYF), and Yiqi Zishen formula(YZF), on inflammatory response, protease-anti-protease imbalance and collagen deposition in rats.METHODS: In present work, we used an in vitro model of cigarette smoking extract(CSE)-and tumor necrosis factor-α(TNF-α)-induced A549 cellsto examine the efficacy of BJF, BYF and YZF on the production of inflammatory cytokines, including TNF-α and interleukin(IL)-8, IL-6, matrix metalloproteinases(MMP)-9, and IL-10 in CSE or TNF-ls. And their related transcripα-induced A549 celtion factors and signaling pathway were also analyzed.RESULTS: The results showed that BJF, BYF and YZF could significantly decrease the expression levels of the pro-inflammatory cytokines induced by CSE or TNF-α. Furthermore, BJF, BYF and YZF could suppress CSE-or TNF-α-induced activation of nuclear factor-kappa B(NF-κB) transcription factors and its corresponding pathways. Taken together, these data implied that BJF, BYF and YZF effectively inhibited CSE-or TNF-α-induced inflammatory response in alveolar epithelial cell, which was due to their inhibition effect on NF-κB pathways.CONCLUSION: Our findings suggest that the Tiaobu Feishen therapies may protect human alveolar epithelial cells against cigarette smoking and TNF-α-induced inflammation. NF-κB pathway may involve in the actions. | Chen Yulong Wu Yaosong Li Jiansheng Feng Suxiang Hao Lili Liu Xuefang Zheng Wanchun Dong Haoran Qin Yanqin Yin Sugai Zhao Peng | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 4 |
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