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| 1 | Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism显示文摘Amycolatopsis mediterranei 被用于 rifamycin 的工业规模生产,它在 antimycobacterial 治疗起一个重要作用。作为类 Amycolatopsis 的首先定序的染色体, 236 715 底配对的包括 10 的紧张 U32 的染色体,最大的原核生物的染色体之一到目前为止曾经被定序。不同于在 streptomycetes 发现的线性拓扑学,这个染色体是圆形的,特别地类似于 Saccharopolyspora erythraea 和奴卡氏菌属 farcinica,在发展史和分类代表他们的靠近的关系。尽管在 A 预言了 9 228 编码蛋白质的基因。mediterranei 染色体 S 与那些分享了 orthologs 的最大的数字。erythraea,它被 Streptomyces coelicolor 而非 N 出人意料地跟随。farcinica,显示不同新陈代谢的特征经由改编演变到多样的生态的壁龛。除类似于那的一个核心区域以外在 streptomycetes 普通,有典型核心特征的一个新奇“伪核心”在非核心区域以内被定义,在 21 从 26 基因为第二等的代谢物生产聚类的总数被定位的地方。位于核心的 rifamycin 生合成基因簇为 rifamycin SV 的变换编码细胞色素 P450 酶必需品到 B,由比作 rifamycin 生产 B 紧张 S699 的高度相应的簇揭示了并且进一步由基因互补证实了。A 的 genomic 信息。mediterranei 表明在看起来复杂的规章的机制的控制下面不仅为各种各样的碳来源和无机的氮混合物的广泛的利用而且为新陈代谢的中介的有效 funneling 安排进第二等的抗菌素合成进程的一个新陈代谢的网络。 | Wei Zhao Yi Zhong Hua Yuan Jin Wang Huajun Zheng Ying Wang Xufeng Cen Feng Xu Jie Bai Xiaobiao Han Gang Lu Yongqiang Zhu Zhihui Shao Han Yan Chen Li Nanqiu Peng Zilong Zhang Yunyi Zhang Wei Lin Yun Fan Zhongjun Qin Yongfei Hu Baoli Zhu Shengyue Wang Xiaoming Ding Guo-Ping Zbao | 2010 | Cell Research2010，20，10： | 10 |
| 2 | Hydrodynamics and Mass Transfer in a Modified Three-phase Airlift Loop Reactor显示文摘A modified internal-loop airlift reactor (MIALR) with a continuous slurry phase was studied to investigate the local hydrodynamic characteristics, including gas holdup, bubble size, bubble rise velocity and local mass transfer properties. Based on the analysis of geometrical construction and fluid properties of gas and slurry, MIALR was divided into six flow regions. In these flow regions, the local hydrodynamic characteristics were investigated over a wide range of operating variables. Furthermore, a new method was developed to measure the dissolved oxygen concentration. The volumetric mass-transfer coefficient in six flow regions was also calculated for comparison. | Liu Mengxi Lu Chunxi Shi Mingxian Ge Baoli Huang Jie | 2007 | Petroleum Science2007，4，3： | 5 |
| 3 | Experimental demonstration of the three-phase-shifted DFB semiconductor laser with buried heterostructure using common holographic exposure显示文摘In this article,we report the first experimental demonstration of the three-phase-shifted(3PS)DFB semiconductor laser with buried heterostructure based on the Reconstruction-Equivalent-Chirp(REC)technique.The simulation results show that the performances of the equivalent 3PS DFB semiconductor laser are nearly the same as those of the true 3PS laser.Compared with the quarter-wave-phase shift(QWS)DFB semiconductor laser,the 3PS DFB semiconductor laser shows better single-longitude-mode(SLM)property even at high injection current with high temperature.However,it only changes theμm-level sampling structures but the seed grating is uniform using the REC technique.Therefore,its fabrication cost is low. | LU LinLin CAO BaoLi ZHANG LiBo TANG Song LI LianYan LI SiMin SHI YueChun CHEN XiangFei | 2014 | Science China(Technological Sciences)2014，57，11： | 4 |
| 4 | RNA interference-mediated silencing of vATPase subunits A and E affect survival and development of the 28-spotted ladybeetle,Henosepilachna vigintioctopunctata显示文摘RNA interference(RNAi)has emerged as a powerful tool for developing novel management strategies for controlling insect pests.The 28-spotted ladybeetle,Henosepilachna vigintioctopunctata is one of the most important pests attacking solanaceous plants in Asia.In this study,the potential of dietary RNAi to manage H.vigintioctopunctata was investigated using both in vitro synthesized and bacterially expressed double-stranded RNAs(dsRNAs)of HvvATPase A and HvvATPase E.The expression levels of HvvATPase A and HvvATPase E were higher in Malpighian tubules than in other tissue types.The silencing of HvvATPase A and HvvATPase E led to significant mortality in H.vigintioctopunctata larvae.In addition,the ingestion of HvvATPase A and HvvATPase E significantly deterred feeding behavior and subsequently arrested the development of H.vigintioctopunctata.Notably,the bacterially expressed dsRNAs consistently caused higher mortality in larvae and adults.Finally,the nontarget effects of the dsRNAs of H.vigintioctopunctata on the predatory ladybeetle Propylaea japonica were evaluated.P.japonica 1st instar larvae were administered vATPase A and vATPase E dsRNAs from H.vigintioctopunctata and P.japonica under the worst-case scenario,in which dsGFP served as negative control.There were significant effects of dsHvvATPase A on P.japonica at the transcriptional level but not at the organismal level,whereas dsHvvATPase E did not effect P.japonica at either the transcriptional or the organismal level.Collectively,the results of the study suggest that HvvATPase A and HvvATPase E can act as novel molecular targets for the control of H.vigintioctopunctata. | Wei Guo Mujuan Guo Chunxiao Yang Zhuoqi Liu Shimin Chen Jing Lu Baoli Qiu Youjun Zhang Xuguo Zhou Huipeng Pan | 2021 | Insect Science2021，28，6： | 3 |
| 5 | An unexpected similarity between antibiotic-resistant NDM-1 and beta-lactamaseⅡfrom Erythrobacter litoralis显示文摘NDM-1(New Delhi metallo-beta-lactamase)gene encodes a metallo-beta-lactamase(MBL)with high carbapenemase activity,which makes the host bacterial strain easily dispatch the last-resort antibiotics known as carbapenems and cause global concern.Here we present the bioinformatics data showing an unexpected similarity between NDM-1 and beta-lactamase II from Erythrobacter litoralis,a marine microbial isolate.We have further expressed these two mature proteins in E.coli cells,both of which present as a monomer with a molecular mass of 25 kDa.Antimicrobial susceptibility assay reveals that they share similar substrate specificities and are sensitive to aztreonam and tigecycline.The conformational change accompanied with the zinc binding visualized by nuclear magnetic resonance,Zn2+-bound NDM-1,adopts at least some stable tertiary structure in contrast to the metal-free protein.Our work implies a close evolutionary relationship between antibiotic resistance genes in environmental reservoir and in the clinic,challenging the antimicrobial resistance monitoring. | Beiwen Zheng Shuguang Tan Jia Gao Huiming Han Jun Liu Guangwen Lu Di Liu Yong Yi Baoli Zhu George F.Gao | 2011 | Protein & Cell2011，2，3： | 2 |
| 6 | Topic tracking with time granularity reasoning显示文摘 | Li Baoli Li Wenjie Lu Qin | 2006 | ACM Transactions on Asian Language Informa- tion Processing2006，5，4： | 1 |
| 7 | An adaptive k-nearest neighbor text categorization strategy显示文摘 | LI Baoli LU Q YU Shiwen | 2004 | ACM Transactions on Asian Language Information Processing2004，12，31： | 1 |
| 8 | Interactions between water deficits, ABA and provenances in Picea asperata显示文摘 | DUAN Baoli YANG Yongqing LU Yanwei HELENA K FRANK B LI CY | 2007 | Journal of Experimental Bota- ny2007，58，： | 1 |
| 9 | Interactions between water deficit, ABA, and provenances in Picea asperata显示文摘 | Duan Baoli Yang Yongqing Lu Yanwei | 2007 | J Exp Bot2007，58，： | 1 |
| 10 | Highly 3,4-selective liv- ing polymerization of isoprene with rare earth metal fluorenyl N-heterocyclic carbine precursors 显示文摘 | Wang Baoli Cui Dongmer LU Kui | 2008 | Macromolecules2008，41，17： | 1 |
| 11 | Differences in growth and physiological traits of Populus cathayana populations as affected by enhanced UV-B radiation and exogenous ABA显示文摘 | Yanwei Lu Baoli Duan Xiaolu Zhang Helena Korpelainen Chunyang Li | 2008 | Environmental and Experimental Botany2008，，1： | 1 |
| 12 | Genesis of calcite vein in basalt and its effect on reservoir quality: A case study of the Carboniferous in the east slope of Mahu sag, Junggar Basin, NW China显示文摘The characteristics and genesis of the calcite veins in Carboniferous basalt in the east slope of Mahu Sag,Junggar Basin are investigated based on observation of cores and thin sections;analyses of X-ray fluorescence,in situ major,trace and rare earth elements(REE),carbon,oxygen and strontium isotopes,fluid inclusions,as well as basin modeling.There are three periods of calcite fillings.The Period I calcite is characterized by low Mn content,flat REE pattern,strong negative cerium(Ce)anomaly,weak to moderate negative Eu anomaly,and light carbon isotopic composition,indicating the formation of the calcite was affected by meteoric water.The Period II calcite shows higher Mn and light REE contents,weak positive Ce anomaly and slight positive europium(Eu)anomaly,and a little heavier carbon isotopic composition and slightly lower strontium isotope ratio than the Period I calcite,suggesting that deep diagenetic fluids affected the formation of the Period II calcite to some extent.The Period III calcite is rich in iron and manganese and has REE pattern similar to that of the Period II calcite,but the cerium and europium enomalies vary significantly.The Period I and II calcites were formed in shallow diagenetic environment at approximately 250–260 Ma,corresponding to Late Hercynian orogeny at Late Permian.The PeriodⅢcalcite was probably formed in the Indo-China movement during Late Triassic.It is believed that the precipitation of calcite in basalt fractures near unconformity was related to leaching and dissolution of carbonates in the overlying Lower Permian Fengcheng Formation by meteoric water,which destructed the Carboniferous weathering crust reservoirs in early stage.Relatively high quality reservoirs could be developed in positions with weak filling and strong late dissolution,such as structural high parts with Fengcheng Formation missing,distant strata from Fengcheng Formation vertically,buried hills inside lake basin,etc. | XIA Lu CAO Yingchang BIAN Baoli LIU Hailei WANG Xiaoxue ZHAO Yiwei YAN Miaomiao | 2021 | Petroleum Exploration and Development2021，48，4： | 0 |
| 13 | Multi-dimensional multiplexing optical secret sharing framework with cascaded liquid crystal holograms显示文摘Secret sharing is a promising technology for information encryption by splitting the secret information into different shares.However,the traditional scheme suffers from information leakage in decryption process since the amount of available information channels is limited.Herein,we propose and demonstrate an optical secret sharing framework based on the multi-dimensional multiplexing liquid crystal(LC)holograms.The LC holograms are used as spatially separated shares to carry secret images.The polarization of the incident light and the distance between different shares are served as secret keys,which can significantly improve the information security and capacity.Besides,the decryption condition is also restricted by the applied external voltage due to the variant diffraction efficiency,which further increases the information security.In implementation,an artificial neural network(ANN)model is developed to carefully design the phase distribution of each LC hologram.With the advantage of high security,high capacity and simple configuration,our optical secret sharing framework has great potentials in optical encryption and dynamic holographic display. | Keyao Li Yiming Wang Dapu Pi Baoli Li Haitao Luan Xinyuan Fang Peng Chen Yanqing Lu Min Gu | 2024 | Opto-Electronic Advances2024，7，1： | 0 |
| 14 | Diagnosis,Treatment,and Associated Factors Among Patients with HCV Infection—Jiangsu Province,China,2004–2020显示文摘Summary What is already known on this topic?The global efforts to address the hepatitis C virus(HCV)are progressing,but there are still significant gaps in the diagnosis and treatment of HCV,leading to an increasing number of deaths related to HCV.What is added by this report?An extensive investigation was conducted to assess HCV RNA diagnosis,treatment uptake,and associated factors among individuals infected with HCV within Jiangsu Province.The study encompassed a large geographical area and utilized a substantial sample size.What are the implications for public health practice?Implementing focused interventions to improve the timely diagnosis of HCV RNA and increase the uptake of HCV treatment could effectively reduce the future burden of HCV-related health problems,deaths,and healthcare expenses.This is essential for achieving the global target of eliminating hepatitis C. | Dandan Yang Jing Lu Zhi Zhang Chuanwu Sun Zhuping Xu Yao Qi XiaoXia Liu Huan Ding Feifei Chai Zhengdong Zhang Baoli Zhu | 2024 | China CDC weekly2024，6，1： | 0 |
| 15 | TBNN: totally-binary neural network for image classification显示文摘Most binary networks apply full precision convolution at the first layer. Changing the first layer to the binary convolution will result in a significant loss of accuracy. In this paper, we propose a new approach to solve this problem by widening the data channel to reduce the information loss of the first convolutional input through the sign function. In addition, widening the channel increases the computation of the first convolution layer, and the problem is solved by using group convolution. The experimental results show that the accuracy of applying this paper's method to state-of-the-art(SOTA) binarization method is significantly improved, proving that this paper's method is effective and feasible. | ZHANG Qingsong SUN Linjun YANG Guowei LU Baoli NING Xin LI Weijun | 2023 | Optoelectronics Letters2023，19，2： | 0 |
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