|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prevalence of Autism Spectrum Disorder in China:A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years显示文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children. | Hao Zhou Xiu Xu Weili Yan Xiaobing Zou Lijie Wu Xuerong Luo Tingyu Li Yi Huang Hongyan Guan Xiang Chen Meng Mao Kun Xia Lan Zhang Erzhen Li Xiaoling Ge Lili Zhang Chunpei Li Xudong Zhang Yuanfeng Zhou Ding Ding Andy Shih Eric Fombonne Yi Zheng Jisheng Han Zhongsheng Sun Yong-hui Jiang Yi Wang LATENT-NHC Study Team | 2020 | Neuroscience Bulletin2020，36，9： | 158 |
| 2 | Estimation of biomass in wheat using random forest regression algorithm and remote sensing data显示文摘Wheat biomass can be estimated using appropriate spectral vegetation indices.However,the accuracy of estimation should be further improved for on-farm crop management.Previous studies focused on developing vegetation indices,however limited research exists on modeling algorithms.The emerging Random Forest(RF) machine-learning algorithm is regarded as one of the most precise prediction methods for regression modeling.The objectives of this study were to(1) investigate the applicability of the RF regression algorithm for remotely estimating wheat biomass,(2) test the performance of the RF regression model,and(3) compare the performance of the RF algorithm with support vector regression(SVR) and artificial neural network(ANN) machine-learning algorithms for wheat biomass estimation.Single HJ-CCD images of wheat from test sites in Jiangsu province were obtained during the jointing,booting,and anthesis stages of growth.Fifteen vegetation indices were calculated based on these images.In-situ wheat above-ground dry biomass was measured during the HJ-CCD data acquisition.The results showed that the RF model produced more accurate estimates of wheat biomass than the SVR and ANN models at each stage,and its robustness is as good as SVR but better than ANN.The RF algorithm provides a useful exploratory and predictive tool for estimating wheat biomass on a large scale in Southern China. | Li'ai Wang Xudong Zhou Xinkai Zhu Zhaodi Dong Wenshan Guo | 2016 | The Crop Journal2016，4，3： | 30 |
| 3 | Simulation of dam breach development for emergency treatment of the Tangjiashan Quake Lake in China显示文摘The Tangjiashan Quake Lake is the largest quake lake triggered by the 5.12 Wenchuan Earthquake that happened on May 12,2008 in China,posing high risk of catastrophic flash flood hazards to downstream human life and properties.A physics-based numerical simulation approach is proposed for real-time prediction of dam breach development of the Tangjiashan Quake Lake in the case of emergency treatment.Bed erosion and lateral development of the dam breach are represented through accounting for the underlying physics including selective sediment transport and gravitational collapse.Conceptualized breach erosion model that involves few parameters enables quick calibration based on the monitored hydrological data in emergency analysis where fully geotechnical information about the barrier dam is not available.The process of dam breach development is found to be nonlinear in cascades due to the combined effects of headcutting and bank collapse.The agreement between the simulation results and the observed data shows the applicability of the present approach for emergency analysis of quake lakes.Limitations will arise in the situation where the soil composition of barrier dam is significantly inhomogeneous.Incorporation of circular arc failure for cohesive soil and lateral seepage in bank slope will also enhance its applicability to complex situations. | WANG GuangQian,LIU Fan,FU XuDong & LI TieJian State Key Laboratory of Hydroscience and Engineering,Tsinghua University,Beijing 100084,China | 2008 | Science China(Technological Sciences)2008，51，S2： | 25 |
| 4 | Human gut microbiota: the links with dementia development显示文摘痴呆是是足够很好的影响工作的一份人日报的大脑疾病的一个全面范畴。痴呆的最普通的类型是 Alzheimers 疾病,它做大多数盒子。新研究显示胃肠的道 microbiota 直接通过触发新陈代谢的疾病和低档发炎进步被连接到痴呆致病。新奇策略通过 ? microbiota 的调整为痴呆和另外的相关疾病的精神病学的治疗为这些混乱并且作为一个助手的管理被建议 ?( 例如与 probiotics 的使用) 。 | Rashad Alkasir Jing Li Xudong Li Miao Jin Baoli Zhu | 2017 | Protein & Cell2017，8，2： | 23 |
| 5 | 2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma显示文摘The incidence of papillary thyroid carcinoma(PTC)has exponentially increased in recent years.Papillary thyroid microcarcinoma(PTMC)accounts for the majority of the reported cases of PTC.The debates and crucial issues in PTMC management have received researchers'attention.To further improve the clinical management of PTMC in China, | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Li Gao Zhuming Guo Tao Huang Xiaoming Huang Xiaoming Li Yansong Lin Qinjiang Liu Xin Ni Yi Pan Jianwu Qin Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Daiwei Zhao Naisong Zhang ShengZhang Ying Zheng Jingqiang Zhu Dapeng Li Xiangqian Zheng 无 | 2017 | Cancer Biology & Medicine2017，14，3： | 23 |
| 6 | A Strigolactone Biosynthesis Gene Contributed to the Green Revolution in Rice显示文摘Plant architecture is a complex agronomic trait and a major factor of crop yield,which is affected by several important hormones.Strigolactones(SLs)are identified as a new class hormoneinhibiting branching in many plant species and have been shown to be involved in various developmental processes.Genetical and chemical modulation of the SL pathway is recognized as a promising approach to modify plant architecture.However,whether and how the genes involved in the SL pathway could be utilized in breeding still remain elusive.Here,we demonstrate that a partial loss-of-function allele of the SL biosynthesis gene,HIGH TILLERING AND DWARF 1/DWARF17(HTD1/D17),which encodes CAROTENOID CLEAVAGE DIOXYGENASE 7(CCD7),increases tiller number and improves grain yield in rice.We found that the HTD1 gene had been widely utilized and co-selected with Semidwarf 1(SD1),both contributing to the improvement of plant architecture in modern rice varieties since the Green Revolution in the 1960s.Understanding how phytohormone pathway genes regulate plant architecture and how they have been utilized and selected in breeding will lay the foundation for developing the rational approaches toward improving crop yield. | Yuexing Wang Lianguang Shang Hong Yu Longjun Zeng Jiang Hu Shen Ni Yuchun Rao Sanfeng Li Jinfang Chu Xiangbing Meng Lei Wang Ping Hu Jijun Yan Shujing Kang Minghao Qu Hai Lin Tao Wang Quan Wang Xingming Hu Hongqi Chen Bing Wang Zhenyu Gao Longbiao Guo Dali Zeng Xudong Zhu Guosheng Xiong Jiayang Li Qian Qian | 2020 | Molecular Plant2020，13，6： | 23 |
| 7 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 8 | A Possible Dynamic Mechanism for Rapid Production of the Extreme Hourly Rainfall in Zhengzhou City on 20 July 2021显示文摘In this study,the unprecedented extreme rainfall event during 19-20 July 2021,which caused devastating flooding in Zhengzhou City and its nearby areas,is examined based on observational data analysis and WRF model 40-h simulations on 1-km horizontal resolution.The results show that the model successfully reproduces(i)major synopticscale weather systems(i.e.,the western Pacific subtropical high,the Tibetan high,two typhoons,and the Huang-Huai cyclone),(ii)convective initiation along the east to north edge of the Songshan Mountain,where orographic lifting is obvious,and(iii)subsequent formation of the convective storm producing the extreme rainfall in Zhengzhou.In particular,the model generates the maximum rainfall rate of 233 mm h^(-1)and 40-h accumulated rainfall of 704 mm,corresponding well to the observed extreme values of 201.9 mm h^(-1)and 818 mm,at nearly observed timing and location.Importantly,the model reproduces an intense quasi-stationary,well-organized meso-γ-scale convective system,surrounded by an arc-shaped convergence zone,allowing the development of convective updrafts in a three-quarter circle around the convective system,in a way similar to“multidirectional pumping,”attracting all associated precipitation overlaid and concentrated into the same trailing region to generate the extreme hourly rainfall over Zhengzhou.Our study emphasizes the significant contribution of the unique dynamic structure of the well-organized meso-γ-scale convective system to the record-high hourly rainfall.A possible dynamic mechanism for short-time extreme rainfall production is proposed.That is,the arc-shaped convergence zone of the mesoscale convective system,acting like multidirectional lifting pumps,transports precipitation from different directions into the same region,and thus produces the extreme rainfall.The results gained herein may shed new light on better understanding and forecasting of short-time extreme rainfall. | Jinfang YIN Haodong GU Xudong LIANG Miao YU Jisong SUN Yanxin XIE Feng LI Chong WU | 2022 | Journal of Meteorological Research2022，36，1： | 17 |
| 9 | Deformation Behavior of Medium-strength TA18 High-pressure Tubes During NC Bending with Different Bending Radii显示文摘To improve the forming quality and forming limit of the numerical control (NC) bending of high-pressure titanium alloy tubes, in this study, using three-dimensional (3D) finite element method, deformation behavior of medium-strength TA18 high-pressure tubes during NC bending with different bending radii is investigated. The results show that the cross-sectional deformation and the wall thickness variation during NC bending of TA18 tubes using a small bending radius (less than 2 times of tube outside diameter) are clearly different from that using a normal bending radius (between 2 and 4 times of tube outside diameter). For bending with a normal bending radius, with or without a mandrel, the distribution of the flattening in the bending area resembles a platform and an asymmetric parabola, respectively. For bending with a small bending radius, with or without a mandrel, the flattening both distributes like a parabola, but the former has a stable peak which deflects toward the initial bending section, and the latter has a more pronounced peak with a bending angle and deflects slightly toward the bending section. The wall thickness variations with a normal bending radius, with and without a mandrel, both resemble a platform when the bending angle exceeds a certain angle. For the bending with a small radius, the distribution of the wall thickness variation without a mandrel follows an approximate parabola which increases in value as the bending angle increases. If a mandrel is used, the thickening ratio increases from the initial bending section to the bending section. | JIANG Zhiqiang ZHAN Mei YANG He XU Xudong LI Guangjun | 2011 | Chinese Journal of Aeronautics2011，24，5： | 16 |
| 10 | Patterns of DNA cytosine methylation between haploids and corresponding diploids in rice显示文摘Eighteen pairs of diploid-haploid twin-seedlings were identified and screened out fromspecial rice SARII-628 population. Five pairs of themwere selected and randomly designated as A, B, C, Dand E. Simple sequence repeats (SSR) analysisshowed that there was no difference among 310 siteswhich indicated that there was no base mutation onDNA primary structure. DNA methylation plays animportant role in gene expression regulation duringgrowth and development stages in eukaryotes. Amodified AFLP technique (methylation-sensitiveAFLP, MSAP) was employed to detect the DNA me-thylation patterns in the 5′-CCGG sites of the fivepairs of twin-seedlings. Although no methylationmutation was detected among the five diploids,forty-three methylation mutation sites were foundfrom the corresponding haploids. The MSAP ratios,which were the ratios of MSAP sites to the total am-plified sites, in five haploids were 18.79%, 19.35%,18.49%, 18.45% and 18.75%, respectively. And cor-responding full methylation levels (5′-CmCGG indouble strands) of those haploids were 10.58%,11.3%, 10.11%, 10.09% and 10.34%, respectively.Both MSAP and full methylation levels in the fivehaploids were higher than that of their correspondingdiploids, which suggested that hypermethylation oc-curred in some 5′-CCGG sites. Five types of MASPpatterns among the five pairs of twin-seedlings weredetected as follows: (1) no changes, methylation lev-els were the same in both haploids and diploids; (2) demethylation, diploid was methylated but no me-thylation in the same site in haploid; (3) hypermethy-lation, the methylation level in haploid was higher than those in diploid; (4) hypomethylation, methyla-tion in haploid was lower than those in diploid; (5) undecided pattern, change trend of methylation lev-els in haploids was not decided. The bands of 18 sites were reclaimed, then sequenced and searched on website to determine the sites of those sequences on rice chromosomes. The result showed that the methylation mutation involved the whole rice genome and 12 pairs of chromosomes. The mutation was site-related and there were different mutation sites for different haploids. Compared to diploids, the higher methylation level in haploids might be a readjusting reaction to the decrease in ploidy for the sake of sur-vival. | ZHANG Hongyu PENG Hai LI Yun XU Peizhou WANG Xudong WU Xianjun | 2006 | Chinese Science Bulletin2006，51，14： | 15 |
| 11 | Model and Algorithm for the Optimal Controlled Partitioning of Power Systems显示文摘解列是电力系统在故障时结构完整性得不到保证的情况下分裂为2个或多个孤立稳定运行子系统的过程或操作。及时恰当的主动解列操作将能有效地避免因保护连锁动作使得电力系统被动解列而崩溃所造成的巨额经济损失。结合图论中的相关概念和输电网最优解列的物理过程,建立电力系统最优主动解列断面选择问题的完整数学模型,并基于含连通图约束的背包问题(connected graph constrained knapsack problem,CGKP)及其求解算法提出“搜索+调整”的2阶段求解方法。为降低问题的复杂性,将完整数学模型分解成图的最优平衡分割问题和基于优化潮流的调节问题,并分2个阶段分别求解。其中,图的最优平衡分割问题又被分解成多个CGKP,利用基于含CGKP的图分割方法进行求解。所提出的主动解列策略具有较强理论基础,计算复杂度低,算例的计算结果证明了该模型及算法的正确性和有效性。 | LIN Jikeng LI Shengwen WU Peng WANG Xudong SHAO Guanghui XU Xingwei MA Xin | 2012 | 中国电机工程学报2012，32，13： | 15 |
| 12 | A Comparative Study on the Performance of Typical Types of Bionic Groove Dry Gas Seal based on Bird Wing显示文摘 | Jinbo Jiang Xudong Peng Jiyun Li Yuan Chen | 2016 | Journal of Bionic Engineering2016，13，2： | 15 |
| 13 | Expression profiles of microRNAs after focal cerebral ischemia/reperfusion injury in rats显示文摘Rat models of focal cerebral ischemia/reperfusion injury were established by occlusion of the middle cerebral artery.Microarray analysis showed that 24 hours after cerebral ischemia,there were nine up-regulated and 27 down-regulated microRNA genes in cortical tissue.Bioinformatic analysis showed that bcl-2 was the target gene of microRNA-384-5p and microRNA-494,and caspase-3 was the target gene of microRNA-129,microRNA-320 and microRNA-326.Real-time PCR and western blot analyses showed that 24 hours after cerebral ischemia,bcl-2 mRNA and protein levels in brain tissue were significantly decreased,while caspase-3 mRNA and protein levels were significantly increased.This suggests that following cerebral ischemia,differentially expressed microRNA-384-5p,microRNA-494,microRNA-320,microRNA-129 and microRNA-326 can regulate bcl-2 and caspase-3 expression in brain tissue. | Fengguo Zhai Xiuping Zhang Yue Guan Xudong Yang Yang Li Gaochen Song Lixin Guan | 2012 | Neural Regeneration Research2012，7，12： | 13 |
| 14 | Numerically controlled bending performance of medium strength TA18 titanium alloy tubes under different die sets显示文摘The rapid development of aviation and aerospace technologies has led to increased interest in the application of numerically controlled(NC) technology for bending light-weight titanium alloy tubes.In order to study and develop advanced NC bending technology,it is necessary to understand the bending performance of medium strength TA18(Ti-3Al-2.5V,ASTM Gr.9) titanium alloy tubes during NC bending under different die sets.This paper focuses on the bending performance of medium strength TA18 tubes under different NC bending die sets,including the variations in the stress,strain,wall thickness,cross sectional deformation,and defects.The results show that adding a wiper die to the base die set decreases the radial,hoop,and tangential compressive stress and the tangential compressive strain,and adding a mandrel to the base die set also decreases these stresses,but increases the radial and hoop tensile stress and decreases the hoop compressive strain obviously,and brings about a three-dimensional tensile stress concentration where the mandrel provides support.For the NC bending of medium strength TA18 tubes,the flattening of cross section is more sensitive index than the thinning of wall thickness.Introducing a mandrel can improve the flattening of cross section obviously but it has a little worse effect on the thinning of wall thickness,and adding a wiper die to the base die set can inhibit the occurrence of the inside bulge but worsen the flattening of the cross section remarkably.Considering the above effects of the mandrel and wiper die on bending performance,it is reasonable to apply the die set comprising a bending die,clamp die,and pressure die for tubes with a small diameter and the die set including an appropriate mandrel additionally for tubes with a larger diameter,in order to bend the medium strength TA18 tubes with high quality and at low cost. | ZHAN Mei JIANG ZhiQiang YANG He XU XuDong LI GuangJun | 2011 | Science China(Technological Sciences)2011，54，4： | 13 |
| 15 | Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2显示文摘MicroRNAs (miRNAs ) 是与癌症的致病有关的小非编码的 RNA 并且仔细的一个班。增加的证据显示 miR-30a 在癌症的发展期间起一个深刻作用。然而,在 non-small-cell 肺癌症(NSCLC ) 的 miR-30a 的功能仍然是模糊的。这里,我们发现 miR-30a 被 qRT-PCR 从 14 个病人在肺腺癌 A549 房间并且在织物样品减少,并且也发现在 A549 房间的 miR-30a 的 overexpression 由愈合创伤的试金禁止了移植和侵略然而并非房间增长和房间周期前进, matrigel 侵略试金,基于山的房间增长试金,和流动 基于cytometry 的房间周期分析分别地。我们进一步在肺腺癌房间行探索了 miR-30a-mediated 基因规定的潜在的机制。EYA2 是 miR-30a 的一个预言的目标,并且 EYA2 表示被 miR-30a 在乳癌房间禁止,这被发现了。我们证明 EYA2 是由在 A549 房间使用双酶的记者试金的 miR-30a 的一个直接目标并且证明 EYA2 蛋白质层次相反地在 A549 和 BEAS-2B 房间与 miR-30a 表示被相关。另外,我们也与表示向量和 miR-30a 模仿的 EYA2 由 cotransfection 在 A549 房间证实了 EYA2 overexpression 的营救效果。一起拿,我们的结果证明在肺腺癌 A549 房间的 miR-30a 的 overexpression 能禁止房间移植和侵略,它部分被归因于 EYA2 的减少表示。我们的调查结果建议 miR-30a 以后可以为肺腺癌的治疗被用作一个新潜在的目标。 | Yuncang Yuan Shangyong Zheng Qian Li Xudong Xiang Tangxin Gao Pengzhan Ran Lijuan Sun Qionglin Huang Fei Xie Jing Du Chunjie Xiao | 2016 | Acta Biochimica et Biophysica Sinica2016，48，3： | 12 |
| 16 | Developing disease-resistant thermosensitive male sterile rice by multiplex gene editing显示文摘High-quality and disease-resistant male sterile lines have great potential for applications in hybrid rice breeding.We introduced specific mutations into the TMS5,Pi21,and Xa13 genes in Pinzhan intermediate breeding material using the CRISPR/Cas9 multiplex genome editing system.We found that the transgenefree homozygous triple tms5/pi21/xa13 mutants obtained in the T1 generation displayed characteristics of thermosensitive genic male sterility(TGMS)with enhancedresistance to rice blast and bacterial blight.Our study provides a convenient and effective way of converting breeding intermediate material into TGMS lines through multiplex gene editing,which could significantly accelerate the breeding of sterile lines. | Sanfeng Li Lan Shen Ping Hu Qing Liu Xudong Zhu Qian Qian Kejian Wang Yuexing Wang | 2019 | Journal of Integrative Plant Biology2019，61，12： | 11 |
| 17 | Glycine attenuates myocardial ischemia-reperfusion injury by inhibiting myocardial apoptosis in rats显示文摘Glycine is a well-documented cytoprotective agent.However,whether it has a protective effect against myocar-dial ischemia-reperfusion injury in vivo is still unknown.By using an open-chest anesthetized rat model,we found that glycine reduced the infarct size by 21% in ischemia-reperfusion injury rats compared with that in the vehicle-treated MI/R rats.The left ventricular ejection fraction and fractional shortening were increased by 19.11% and 30.98%,respectively,in glycine-treated rats.The plasma creatine kinase levels in ischemia-reperfusion injury rats decreased following glycine treatment.Importantly,administration of glycine significantly inhibited apoptosis in post-ischemia-reperfusion myocardium,which was accompanied by suppression of phosphorylated p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase,as well as the Fas ligand.These results suggest that gly-cine attenuates myocardial ischemia-reperfusion injury in vivo by inhibiting cardiomyocytes apoptosis. | Xiaozheng Zhong Xiaoyu Li Lingling Qiana Yiming Xu Yan Lu Jing Zhang Nan Li Xudong Zhu Jingjing Ben Qing Yang Qi Chen | 2012 | The Journal of Biomedical Research2012，26，5： | 10 |
| 18 | Image edge detection based on beamlet transform显示文摘Combining beamlet transform with steerable filters, a new edge detection method based on line gradient is proposed. Compared with operators based on point local properties, the edge-detection results with this method achieve higher SNR and position accuracy, and are quite helpful for image registration, object identification, etc. Some edgedetection experiments on optical and SAR images that demonstrate the significant improvement over classical edge operators are also presented. Moreover, the template matching result based on edge information of optical reference image and SAR image also proves the validity of this method. | Li Jing Huang Peikang Wang Xiaohu Pan Xudong | 2009 | Journal of Systems Engineering and Electronics2009，20，1： | 10 |
| 19 | Characteristics of ozone pollution and the sensitivity to precursors during early summer in central plain, China显示文摘In this study,we conducted an observation experiment from May 1 to June 30,2018 in Zhengzhou,a major city in central China,where ground ozone(O3)pollution has become serious in recent years.The concentrations of O3 and its precursors,as well as H2O_(2) and meteorological data were obtained from the urban site(Yanchang,YC),suburban(Zhengzhou University,ZZU)and background sites(Ganglishuiku,GLSK).Result showed that the rates of O3 concentration exceeded Chinese National Air Quality Standard GradeⅡ(93.3 ppbv)were 59.0%,52.5%,and 55.7%at the above three sites with good consistency,respectively,indicating that O3 pollution is a regional problem in Zhengzhou.The daily peak O3 appeared at 15:00-16:00,which was opposite to VOCs,NOx,and CO and consistent with H2O_(2).The exhaustive statistical analysis of meteorological factors and chemical effects on O3 formation at YC was advanced.The high concentration of precursors,high temperature,low relative humidity,and moderately high wind speed together with the wind direction dominated by south and southeast wind contribute to urban O3 episodes in Zhengzhou.O3 formation analysis showed that reactive alkenes such as isoprene and cis-2-butene contributed most to O3 formation.The VOCs/NOx ratio and smog production model were used to determine O3-VOC-NOx sensitivity.The O3 formation in Zhengzhou during early summer was mainly under VOC-limited and transition regions alternately,which implies that the simultaneous emission reduction of alkenes and NOx is effective in reducing O3 pollution in Zhengzhou. | Yasong Li Shasha Yin Shijie YU Ling Bai Xudong Wang Xuan Lu Shuangliang Ma | 2021 | Journal of Environmental Sciences2021，33，1： | 10 |
| 20 | Influence of Mg and Ti on the microstructure and electrochemical performance of aluminum alloy sacrificial anodes显示文摘The experiments focused on the influence of magnesium and titanium as additional alloying elements on the microstructure and electro-chemical behavior of Al-Zn-In sacrificial anodes. The electrochemical behavior of the aluminum sacrificial anode with 3 wt.% sodium chloride solution was studied by electrochemical impedance spectroscopy (EIS) tests. It was found that a microstructure with few precipitates and refined grains could be achieved by adding 1 wt.% Mg and 0.05 wt.% Ti to the Al-Zn-In alloy,resulting in the improved current capacity and efficiency of the alloy. The equivalent circuit based on the EIS experimental data revealed less corrosion and lower adsorbed corrosion production on the surface of the aluminum alloy with a combination of 1 wt.% Mg and 0.05 wt.% Ti,which suggested that the corrosion behavior seemed to be strongly related to the presence of precipitate particles in the aluminum alloy,and moderate amounts of precipitate particles could be beneficial to the electrochemical performance of the aluminum alloy sacrificial anode. | Ma Jingling Wen Jiuba Li Xudong Zhao Shengli Yan Yanfu | 2009 | Rare Metals2009，28，2： | 9 |
您所在的机构暂未开通此部分的功能，请联系管理员