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| 1 | Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020显示文摘African swine fever virus(ASFV)has been circulating in China for more than two years,and it is not clear whether the biological properties of the virus have changed.Here,we report on our surveillance of ASFVs in seven provinces of China,from June to December,2020.A total of 22 viruses were isolated and characterized as genotype II ASFVs,with mutations,deletions,insertions,or short-fragment replacement occurring in all isolates compared with Pig/HLJ/2018(HLJ/18),the earliest isolate in China.Eleven isolates had four different types of natural mutations or deletion in the EP402R gene and displayed a nonhemadsorbing(non-HAD)phenotype.Four isolates were tested for virulence in pigs;two were found to be as highly lethal as HLJ/18.However,two non-HAD isolates showed lower virulence but were highly transmissible;infection with 106 TCID50 dose was partially lethal and caused acute or sub-acute disease,whereas 103 TCID50 dose caused non-lethal,sub-acute or chronic disease,and persistent infection.The emergence of lower virulent natural mutants brings greater difficulty to the early diagnosis of ASF and creates new challenges for ASFV control. | Encheng Sun Zhenjiang Zhang Zilong Wang Xijun He Xianfeng Zhang Lulu Wang Wenqing Wang Lianyu Huang Fei Xi Haoyue Huangfu Ghebremedhin Tsegay Hong Huo Jianhong Sun Zhijun Tian Wei Xia Xuewu Yu Fang Li Renqiang Liu Yuntao Guan Dongming Zhao Zhigao Bu | 2021 | Science China(Life Sciences)2021，64，5： | 46 |
| 2 | Involvement of Histone Modifcations in Plant Abiotic Stress Responses显示文摘As sessile organisms,plants encounter various environmental stimuli including abiotic stresses during their lifecycle.To survive under adverse conditions,plants have evolved intricate mechanisms to perceive external signals and respond accordingly.Responses to various stresses largely depend on the plant capacity to modulate the transcriptome rapidly and specifcally.A number of studies have shown that the molecular mechanisms driving the responses of plants to environmental stresses often depend on nucleosome histone post‐translational modifcations including histone acetylation,methylation,ubiquitination,and phosphorylation.The combined effects of these modifcations play an essential role in the regulation of stress responsive gene expression.In this review,we highlight our current understanding of the epigenetic mechanisms of histone modifcations and their roles in plant abiotic stress response. | Lianyu Yuan Xuncheng Liu Ming Luo Songguang Yang Keqiang Wu | 2013 | Journal of Integrative Plant Biology2013，55，10： | 21 |
| 3 | Rapid and robust initialization for monocular visual inertial navigation within multi-state Kalman filter显示文摘Sensor-fusion based navigation attracts significant attentions for its robustness and accuracy in various applications.To achieve a versatile and efficient state estimation both indoor and outdoor, this paper presents an improved monocular visual inertial navigation architecture within the Multi-State Constraint Kalman Filter(MSCKF).In addition, to alleviate the initialization demands by appending enough stable poses in MSCKF, a rapid and robust Initialization MSCKF(I-MSCKF) navigation method is proposed in the paper.Based on the trifocal tensor and sigmapoint filter, the initialization of the integrated navigation can be accomplished within three consecutive visual frames.Thus, the proposed I-MSCKF method can improve the navigation performance when suffered from shocks at the initial stage.Moreover, the sigma-point filter is applied at initial stage to improve the accuracy for state estimation.The state vector generated at initial stage from the proposed method is consistent with MSCKF, and thus a seamless transition can be achieved between the initialization and the subsequent navigation in I-MSCKF.Finally, the experimental results show that the proposed I-MSCKF method can improve the robustness and accuracy for monocular visual inertial navigations. | Wei FANG Lianyu ZHENG | 2018 | Chinese Journal of Aeronautics2018，31，1： | 8 |
| 4 | Ultrasensitive detection of cancer biomarker microRNA by amplification of fluorescence of lanthanide nanoprobes显示文摘癌症 biomarker microRNAs (miRNAs ) 的敏感察觉具有为癌症诊断和治疗的重要重要性。尽管如此,在存在 miRNA 生物鉴定的察觉敏感被 miRNA 的结构的特征严重地限制(包括小长度和高顺序相同) 因为大多数这些方法基于目标扩大。此处,我们经由 nanoprobe 的唯一的策略向低丰富的 miRNA 的敏感、特定的察觉汇报一条新奇途径提高溶解的荧光扩大,展示分子的烽火结构的一根俘获探针在被设计。借助于这策略, miRNA-21 与象 1.38 fM 一样低的察觉限制从 10 fM 在一个线性范围被检测到 100 下午。最新发达的生物传感器的高选择被对一个目标的好歧视与单个底的失配表明。而且,这试金被用于低于 10.1% 在 90.2%-108% 的范围和变化的系数与恢复增加进胎儿的牛的浆液样品的 miRNA-21 的察觉,显示它到在新窗户中的 RNA 免疫分析和早癌症 diagnosis.Open | Lianyu Lu Datao Tu Yan Liu Shanyong Zhou Wei Zheng Xueyuan Chen | 2018 | Nano Research2018，11，1： | 6 |
| 5 | PacBio Sequencing Reveals Transposable Elements as a Key Contributor to Genomic Plasticity and Virulence Variation in Magnaporthe oryzae显示文摘 | Jiandong Bao Meilian Chen Zhenhui Zhong Wei Tang Lianyu Lin Xingtan Zhang Haolang Jiang Deyu Zhang Chenyong Miao Haibao Tang Jisen Zhang Guodong Lu Ray Ming Justice Norvienyeku Baohua Wang Zonghua Wang | 2017 | Molecular Plant2017，10，11： | 5 |
| 6 | A smart assistance system for cable assembly by combining wearable augmented reality with portable visual inspection显示文摘Background Assembly guided by paper documents is the most widespread type used in the process of aircraft cable assembly.This process is very complicated and requires assembly workers with high-level skills.The technologies of wearable Augmented Reality(AR)and portable visual inspection can be exploited to improve the efficiency and the quality of cable assembly.Methods In this study,we propose a smart assistance system for cable assembly that combines wearable AR with portable visual inspection.Specifically,a portable visual device based on binocular vision and deep learning is developed to realize fast detection and recognition of cable brackets that are installed on aircraft airframes.A Convolutional Neural Network(CNN)is then developed to read the texts on cables after images are acquired from the camera of the wearable AR device.An authoring tool that was developed to create and manage the assembly process is proposed to realize visual guidance of the cable assembly process based on a wearable AR device.The system is applied to cable assembly on an aircraft bulkhead prototype.Results The results show that this system can recognize the number,types,and locations of brackets,and can correctly read the text of aircraft cables.The authoring tool can assist users who lack professional programming experience in establishing a process plan,i.e.,assembly outline based on AR for cable assembly.Conclusions The system can provide quick assembly guidance for aircraft cable with texts,images,and a 3 D model.It is beneficial for reducing the dependency on paper documents,labor intensity,and the error rate. | Lianyu ZHENG Xinyu LIU Zewu AN Shufei LI Renjie ZHANG | 2020 | Virtual Reality & Intelligent Hardware2020，2，1： | 5 |
| 7 | A strategy for accurate detection of glucose in human serum and whole blood based on an upconversion nanoparticles-polydopamine nanosystem显示文摘 | Yan Liu Datao Tu Wei Zheng Lianyu Lu Wenwu You Shanyong Zhou Ping Huang Renfu Li Xueyuan Chen | 2018 | Nano Research2018，11，6： | 5 |
| 8 | Synthesis of Reassortant Infectious Bursal Disease Virus in Chickens Injected Directly with Infectious Clones from Different Virus Strains显示文摘The infectious bursal disease virus (IBDV), a member of the Birnaviridae family, containing a bisegmented double-stranded RNA genome, encodes four structural viral proteins, VP1, VP2, VP3, and VP4, as well as a non-structural protein, VP5. In the present paper, the segment A from two IBDV strains,field isolate ZJ2000 and attenuated strain HZ2, were inserted into one NaeⅠ site by site-directed silent mutagenesis and subcloned into the eukaryotic expression plasmid pCI under the control of the human cytomegalovirus (hCMV) immediate early enhancer and promoter to construct the recombinant plasmids pCI-AKZJ2000 and pCI-AKHZ2, respectively. Each of the two recombinants was combined with another recombinant pCI plasmid containing the marked segment B of strain HZ2 (pCI-mB), and injected intramuscularly into nonimmunized chickens. Two chimeric IBDV strains were recovered from the chickens. Two out of eight chickens in each of two groups showed the bursal histopathological change. The reassortant virus derived from pCI-AKZJ2000/pCI-mB can infect chicken embryos and shows relatively low virulence. We have developed a novel virus reverse genetic approach for the study of IBDV. The results also form the basis for investigating the role of VP1 in viral replication and pathogenecity. | LongLI Yao-WeiHUANG Lian-ShengWANG Wang-JunWAN LianYU | 2005 | Acta Biochimica et Biophysica Sinica2005，37，3： | 3 |
| 9 | A STEP-BASED CAD/CAPP INTEGRATION显示文摘ASTEP-BASEDCADICAPPINTEGRATIONZhengLianyu;DuPeiASTEP-BASEDCADICAPPINTEGRATION￥ZhengLianyu;DuPeiAbstractTheinformationintegrat... | Zheng Lianyu Du Pei | 1994 | Computer Aided Drafting,Design and Manufacturing1994，4，1： | 3 |
| 10 | Antifungal activity and phytochemical investigation of the asexual endophyte of Epichloё sp. from Festuca sinensis显示文摘Dear Editor,Much research is now being conducted on grasses-Epichloё associations.The asexual Epichloё species have attracted much attention over the past 30 years as they can provide benefits to important forage grasses,in particular perennial ryegrass(Lolium perenne),annual ryegrass(L.multiflorum),tall fescue(Festuca arundinacea),and meadow fescue(F. | ZHOU LianYu ZHANG XingXu LI ChunJie CHRISTENSEN Michael John NAN ZhiBiao | 2015 | Science China(Life Sciences)2015，58，8： | 3 |
| 11 | Genetic diversity and differentiation of masu salmon(Oncorhynchus masou masou) between and within cultured populations inferred from microsatellite DNA analysis显示文摘Masu salmon,Oncorhynchus masou masou,is one of the most valuable fishery species that has been introduced to China,though to date no studies on the genetic diversity and genetic relationship among hatchery populations has been performed with molecular markers.We undertook such a study and sampled 120 individuals from three hatchery stocks and analyzed 20 microsatellite loci.All loci were polymorphic and a total of 91 alleles were detected.A relatively low level of genetic diversity was revealed with effective number of allele of 3.1094,3.3299 and 3.1894 and expected heterozygosity of 0.6600,0.6648 and 0.6638 in the three stocks,respectively.Deviations from Hardy-Weinberg equilibrium were found due to heterozygote deficit.Accordingly,evidence of genetic bottlenecks were found in the three stocks.An individual assignment test demonstrated that 85% of individuals were correctly assigned into their original stocks.Pairwise Fst revealed that significant differentiation occurred between these three stocks.The results of the study indicated that disequilibrium of genetic structure and differentiation has occurred in all three stocks.This information collectively provides a basis for measures to avoid of loss of genetic diversity and introgression in Chinese aquaculture. | Zhiying JI Yuyong ZHANG Shuqiang CHEN Lianyu SHI | 2012 | Zoological Research2012，33，4： | 2 |
| 12 | A retrospective analysis of primary gastric diffuse large B-cell lymphoma with or without concomitant mucosa-associated lymphoid tissue (MALT) lymphoma components显示文摘 | Xiaowu Li Bing Xia Shanqi Guo Zhongli Zhan Lianyu Zhang Dandan Zhao Xiaoxiong Wu Yizhuo Zhang | 2013 | Annals of Hematology2013，，6： | 2 |
| 13 | 混合动力车辆使用HOV车道政策研究(英文)显示文摘在拥堵的高速公路上,合乘车辆(HOV)车道是一种高效环保的交通方式.虽然HOV车道广受采纳,但该系统的利用效率受到质疑.加州在全州范围内采取了一项允许混合动力车辆使用HOV车道的政策,以期通过鼓励驾驶员使用省油汽车来减少尾气排放,同时通过更有效地利用HOV车道的剩余通行能缓解交通拥挤.加州橘县高速公路的路网用于研究该政策的影响及有效性.研究方法结合使用传统的规划模型来估计交通需求及校准的微观仿真模型来评价系统性能.通过对系统整体性能、车道服务水平和空气质量三方面的分析,结论表明此政策对在高峰时段没有剩余通行能力的HOV车道带来严重的负面影响.为保证HOV车道服务质量不明显下降还能减少排放,该政策最多允许50 000辆在加州注册的混合动力车辆使用HOV车道. | K S Nesamani Lianyu Chu Will Recker | 2010 | 交通运输系统工程与信息2010，10，2： | 2 |
| 14 | Minimum feasible tariff model for BOT water supply projects in Malaysia 显示文摘 | Lianyu C Tiong R | 2005 | Construction Management and Economics2005，23，3： | 1 |
| 15 | Selective Aerobic Oxidation of Alcohols Catalyzed by Iron Chloride Hexahydrate/ TEMPO in the Presence of Silica Gel 显示文摘 | Wang Lianyue Li Jun LO Ying | 2012 | Appl Organomet Chem2012，26，1： | 1 |
| 16 | An Efficient and Scalable Room Temperature Aerobic Alcohol Oxidation Catalyzed by Iron Chloride Hexahydrate/Mesoporous Silica Supported TEMPO显示文摘 | Wang Lianyue Li Jun Zhao Xianping | 2013 | Tetrahedron2013，69，30： | 1 |
| 17 | A precise evaluation method for adhesion of asphalt aggregate 显示文摘 | XIAO QINGYI WEI LIANYU | 2010 | International Journal of Pavement Research and Technology2010，2，6： | 1 |
| 18 | MicroRNA‐140‐5p suppresses tumor growth and metastasis by targeting transforming growth factor β receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma显示文摘 | Hao Yang Feng Fang Ruimin Chang Lianyue Yang | 2013 | Hepatology2013，，1： | 1 |
| 19 | Organic-inorganic hybrid membranes with simultaneously enhanced flux and selectivity 显示文摘 | Peng Fubing Lu Lianyu Sun Honglei | 2007 | Industrial and Engineering Chemistry Research2007，46，8： | 1 |
| 20 | Experimental study on drilling force in printed circuit board micro drilling process显示文摘 | Hongyan Shi Fumin Song Lianyu Fu | 2011 | Volume 37 Number 12011，，： | 1 |
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