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| 1 | The seasonal dependence of cycle slip occurrence of GPS data over China low latitude region显示文摘The relationship of daily accumulated cycle slip occurrence with the season is analyzed using the GPS data observed in six GPS stations located in China low latitude region in 2001. It is found that the seasonal dependence of cycle slip oc-currence is evident. The cycle slip mainly occurs during the periods of two equinox months (March to May and September to October), and some correlative changes of the cycle slip occurrences over all six stations are exhibited in some special days. Considering the diurnal dependence of cycle slip, it can be inferred that the cycle slip occurrence with certain elevation limitation is related with the iono-spheric irregularities over this region. | ZHANG DongHe FENG Man XIAO Zuo HAO YongQiang SHI LiQin YANG GuangLin SUO YuCheng | 2007 | Science China(Technological Sciences)2007，50，4： | 10 |
| 2 | Synergistic defensive mechanism of phytochelatins and antioxidative enzymes in Brassica chinensis L. against Cd stress显示文摘Brassica chinensis L. was chosen and exposed to different concentrations of Cd exposure to evaluate its Cd-accumulating capacity and its potential cellular defensive mechanisms. Cd accumulation in the shoots and roots of B. chinensis was up to 1348.3±461.8 and 3761.0±795.0 mg per killogram of dry weight, respectively, under 200 μmol/L of Cd exposure. Increasing Cd accumulation in the plant was accompanied by rapid accumulation of phytochelatins (PCs), and the sequestration of Cd by PCs provided a primary cellular mechanism for Cd detoxification and tolerance of B. chinensis. Furthermore, malondialdehyde formation, hydrogen peroxide content and antioxidative enzyme activities such as superoxide dismutase, catalase, guaiacol peroxidase and ascorbate peroxidase were observed in the shoots of Cd-stressed B. chinensis. Increasing enzyme activities in response to concentrations of 5 to 50 μmol/L Cd showed an efficient defense against oxidative stress, suggesting that the antioxidative system was a secondary defensive mechanism. These resulted in reduced free Cd damage and enhanced Cd accumulation and tolerance. Glutathione plays a pivotal role in these two detoxification pathways. In general, these results suggested that PCs and the antioxidative system are synergistic in combatting Cd-induced oxidative stress and that they play important roles in Cd detoxification of B. chinensis, and also give a deep understanding of the natural defensive mechanisms in plants under heavy metal stress. | CHEN LiQin GUO YiFei YANG LiMin WANG QiuQuan | 2008 | Chinese Science Bulletin2008，53，10： | 8 |
| 3 | Evaluation of the transfer function of human pulse system based on signal detection显示文摘On the basis of the pulse source-system model, a convenient and effective method used to evaluate the transfer function of human pulse system has been proposed by using the principle of signal detection and system analysis. The experimental results show that the pulse system of the normal pulse has 3 formants; the smooth pulse, 2 formants; the wiry pulse, 4 formants; and the thready pulse, only 1 formant. Formant frequencies reflect the resonance behaviour of the arterial system. | Binghe Wang Jinglin Xiang Yong Yang Liqin Zhi Wei Zheng | 1999 | Chinese Science Bulletin1999，44，17： | 4 |
| 4 | Potential production and spatial distribution of hybrid poplar as a biofuel crop in Connecticut,USA显示文摘The objective of this study was to assess the biomass production potential from hybrid poplars using marginal lands in the state of Connecticut,USA.A land-use suitability model was developed to identify and classify marginal lands in the state that could be used for growing hybrid poplars as a biofuel woody energy crop.The model was built on a geographic information system(GIS)platform,consisting of an exclusion area section,an ecological suitability section,and an economic/land-use suitability section.The model then was used to estimate the total biomass of the land-cover forests,annual biomass from forest and agricultural residues,and in particular the production potential of biomass from hybrid poplars over marginal lands in the state at county level.The results indicated that about 50%of the land in this state is unavailable for hybrid poplar cultivation and that less than 5%is highly suitable.The amount of usable area is highly variable on the county level.Without large-scale land use change,it appears that biofuel production in this state can only be a supplemental resource to the current energy supply. | Zhao Xue Liqin Qu Xiusheng Yang | 2014 | International Journal of Agricultural and Biological Engineering2014，7，2： | 4 |
| 5 | Atmospheric emission characterization of a novel sludge drying and co-combustion system显示文摘A novel system combining sludge drying and co-combustion with coal was applied in disposing sludge and its atmospheric emission characteristics were tested. The system was composed of a hollow blade paddle dryer, a thermal drying exhaust gas control system,a 75 tons/hr circulating fluidized bed and a flue gas cleaning system. The emissions of NH3, SO2, CH4and some other pollutants released from thermal drying, and pollutants such as NOx, SO2etc. discharged by the incinerator, were all tested. Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans(PCDD/Fs) in the flue gas from the incinerator were investigated as well. The results indicated that the concentrations of NOx and SO2in the flue gas from the incinerator were 145 and 16 mg/m3, respectively,and the I-TEQ concentration of 2,3,7,8-substitued PCDD/Fs was 0.023 ng I-TEQ/Nm3. All these values were greatly lower than the emission standards of China. In addition, there was no obvious odor in the air around the sludge dryer. The results demonstrated that this drying and co-combustion system is efcient in controlling pollutants and is a feasible way for large-scale treatment of industrial sludge and sewage sludge. | Shengyong Lu Liqin Yang Fa Zhou Fei Wang Jianhua Yan Xiaodong Li Yong Chi Kefa Cen | 2013 | Journal of Environmental Sciences2013，25，10： | 3 |
| 6 | The discovery of Jurassic plants in Shenzhen of Guangdong, southern China and related significance显示文摘Investigations of major marine and non-marine geologic and biotic events across the Triassic-Jurassic transition rely predominantly on detailed stratigraphic frameworks and biodiversity analyses. The alternating sequences of marine and terrestrial Triassic-Jurassic formations in Guangdong Province represent one of the most remarkable coal-bearing series in southern China. The Lower Jurassic Jinji Formation is widely distributed in Guangdong, with continuously outcropped sections and rich marine and non-marine fossil fauna. However, as little research has been conducted on fossil plant remains in the Jinji Formation, it is difficult to understand the systematics,diversity, and floral aspects of the Jurassic. Here we report on the recent collection of rich fossil plants from the Jinji Formation in the Dapeng area of Shenzhen, southern Guangdong Province. Our studies demonstrate taxonomical affiliations, preservation status, and diversity features of these plant fossils, which are marked by the close association of densely preserved, pinnae and rachis connected leaves, and the bennettitalean reproductive organs of Williamsoniella, which may represent an Early Jurassic plant community dominated by Otozamites of the bennettitales.This work not only represents the first discovery of fossil plants in the Shenzhen area, but is also the first documentation of Jurassic plants in Guangdong and the Pearl River Delta regions. Research related to these plant fossils will be helpful in the correlation of the Early Mesozoic coal-bearing strata in Guangdong, and will provide a deeper understanding of variations in plant diversity of the Triassic and Jurassic transition in southern China. Additionally, it will provide terrestrial plant evidence for explorations in Jurassic palaeoecology, palaeoclimatology,and palaeogeography of southern China. | Yongdong Wang Xiangwu Wu Xiaoju Yang Wei Duan Liqin Li | 2014 | Chinese Science Bulletin2014，59，28： | 2 |
| 7 | Porous, multi-layered piezoelectric composites based on highly oriented PZT/PVDF electrospinning fibers for high-performance piezoelectric nanogenerators显示文摘Piezoelectric nanogenerators(PENGs)that can harvest mechanical energy from ambient environment have broad prospects for multi-functional applications.Here,multi-layered piezoelectric composites with a porous structure based on highly oriented Pb(Zr_(0.52)Ti_(0.48))O_(3)/PVDF(PZT/PVDF)electrospinning fibers are prepared via a laminating method to construct high-performance PENGs.PZT particles as piezoelectric reinforcing phases are embedded in PVDF fibers and facilitate the formation of polarβphase in PVDF.The multi-layered,porous structure effectively promotes the overall polarization and surface bound charge density,resulting in a highly efficient electromechanical conversion.The PENG based on 10 wt%PZT/PVDF composite fibers with a 220µm film thickness outputs an optimal voltage of 62.0 V and a power of 136.9μW,which are 3.4 and 6.5 times those of 10 wt%PZT/PVDF casting film-based PENG,respectively.Importantly,the PENG shows a high sensitivity of 12.4 V·N^(−1),presenting a significant advantage in comparison to PENGs with other porous structures.In addition,the composites show excellent flexibility with a Young’s modulus of 227.2 MPa and an elongation of 262.3%.This study shows a great potential application of piezoelectric fiber composites in flexible energy harvesting devices. | Xiangxin DU Zheng ZHOU Zhao ZHANG Liqin YAO Qilong ZHANG Hui YANG | 2022 | Journal of Advanced Ceramics2022，11，2： | 2 |
| 8 | A novel apidaecin Api-PR19 synergizes with the gut microbial community to maintain intestinal health and promote growth performance of broilers显示文摘Background: Antibiotic growth promoters(AGPs) have been used as growth promoters to maintain animal intestinal health and improve feed efficiency in broilers by inhibiting pathogen proliferation. In view of the growing emergence of antibiotic-resistant pathogen strains and drug residue issues, novel treatments are increasingly required. This study aimed to compare two antimicrobial approaches for managing pathogen infection and maintaining animal intestinal health in broilers by supplying Apidaecin Api-PR19 and AGPs over 42 d of a feeding trial.Results: Compared with the broilers that were only fed a corn-soybean basal diet(CON group), supplementation with Api-PR19 and AGP(respectively named the ABP and AGP groups) both increased the feed conversion efficiency. When compared with the AGP group, Api-PR19 supplementation could significantly increase the organ index of the bursa of fabricius and subtype H9 antibody level in broiler chickens. Moreover, when compared with the CON group, the intestinal villus height, intestinal nutrient transport, and intestinal s Ig A content were all increased in the Api-PR19 group, while AGP supplementation was harmful to the intestinal villus height and intestinal nutrient transport. By assessing the antibacterial effect of Api-PR19 and antibiotics in vitro and in vivo, we found that Api-PR19 and antibiotics both inhibited the growth of pathogens, including Escherichia coli and Campylobacter jejuni. Furthermore, by using 16 S r RNA gene sequencing, the beneficial bacteria and microbiota in broilers were not disturbed but improved by apidaecin Api-PR19, including the genera of Eubacterium and Christensenella and the species of uncultured_Eubacterium_sp, Clostridium_asparagiforme, and uncultured_Christensenella_sp, which were positively related to improved intestinal development, absorption, and immune function.Conclusion: Apidaecin Api-PR19 treatment could combat pathogen infection and had little negative impact on beneficial bacteria in the gut compared to antibiotic treatment, subsequently improving intestinal development,absorption, and immune function. | Shengru Wu Jian Wang Liqin Zhu Hao Ren Xiaojun Yang | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 2 |
| 9 | Temperature-sensitive polymeric nanogels encapsulating withβ-cyclodextrin and ICG complex for high-resolution deep-tissue ultrasound-switchable fluorescence imaging显示文摘One of the thorny problems currently impeding the applications of the fluorescence imaging technique is the poor spatial resolution in deep tissue.Ultrasound-switchable fluorescence(USF)imaging is a novel imaging tool that has recently been explored to possibly surmount the above-mentioned bottleneck.Herein,αβ-cyclodextrin/indocyanine green(ICG)complex-encapsulated poly(N-isopropylacrylamide)(PNIPAM)nanogel was synthesized and studied for ex vivo/in vivo deep tissue/high-resolution near infrared USF(NIR-USF)imaging.To be specific,our results revealed that the average diameter of the as-prepared nanogels was significantly decreased to-32 nm from-335 nm compared to the reported ICG-PNIPAM nanoparticles.Additionally,the excitation/emission characteristics of the ICG itself in present nanogels were almost completely retained,and the resultant nanogel exhibited high physiological stability and positive biocompatibility.In particular,the signal-to-noise ratio of the USF image for the PNIPAM/P-cyclodextrin/ICG nanogel(33.01±2.42 dB)was prominently higher than that of the ICG-PNIPAM nanoparticles(18.73±0.33 dB)in 1.5-cm-thick chicken breast tissues.The NIR-USF imaging in 3.5-cm-thick chicken breast tissues was achieved using this new probe.The e x v iv o NIR-USF imaging of the mouse liver was also successfully obtained.Animal experiments showed that the present nanogels were able to be effectively accumulated into U87 tumor-bearing mice via enhanced permeability and retention effects,and the high-resolution NIR-USF imaging of in v ivo tumor was efficiently acquired.The metabolism and in vivo biodistribution of the nanogels were evaluated.Overall,the results suggest that the current nanogel is a highly promising NIR-USF probe for deep tissue and high-resolution USF imaging. | Ruilin Liu Tingfeng Yao Yang Liu Shuai Yu Liqin Ren Yi Hong Kytai T.Nguyen Baohong Yuan | 2020 | Nano Research2020，13，4： | 1 |
| 10 | Prevalence of age - related macular degeneration in a rural Chinese population:the hart- dan eye study 显示文摘 | YANG Ke LIANG Yuanbo GAO Liqin | 2011 | Ophthalmology2011，118，7： | 1 |
| 11 | Investigation into the traction coefficient in elasto-hydrodynamic lubrication显示文摘 | Wang Yanshuang Yang Boyuan Wang Liqin | 2004 | Tribotest2004，11，2： | 1 |
| 12 | Active canopy sensor-based precision N management strategy for rice显示文摘 | Yinkun Yao Yuxin Miao Shanyu Huang Lei Gao Xiaobo Ma Guangming Zhao Rongfeng Jiang Xinping Chen Fusuo Zhang Kang Yu Martin Gnyp Georg Bareth Cheng Liu Liqin Zhao Wen Yang Huamin Zhu | 2012 | Agronomy for Sustainable Development2012，，4： | 1 |
| 13 | Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae显示文摘 | Qi Chen Liqin Yu Lihua Yang Bingsheng Zhou | 2012 | Aquatic Toxicology2012，，： | 1 |
| 14 | The MNS16A polymorphism in the TERT gene in peri-centenarians from the Han Chinese population显示文摘MNS16A,a variable number of tandem repeats polymorphism in the TERT gene,has been suggested to regulate telomerase activity.As telomerase activity has been reported to be related to life-span,we hypothesized that this polymorphism might affect human longevity by controlling the length of the telomere.To test this hypothesis,we collected 446 unrelated pericentenarian individuals(age≥90,mean 94.45±3.45 years)and 332 normal controls(age 22-53,mean 35.0±12.0 years)from Dujiangyan,Sichuan,China.We typed the MNS16A polymorphism in both groups,and compared the allele and genotype frequencies between the peri-centenarian and control groups using the chi-squared test.There was no significant difference between the peri-centenarian and control groups.Thus,the MNS16A polymorphism in TERT might not influence human life-span,at least in the Han Chinese population studied here. | LIU LiNa WANG ChengYe LU Xiang XIAO FuHui WANG HuaWei YANG LiQin XU LiangYou KONG QingPeng | 2014 | Science China(Life Sciences)2014，57，10： | 1 |
| 15 | A novel sucrose phosphorylase from the metagenomes of sucrose-rich environment:isolation and characterization World J Microbiol Biotechnol显示文摘 | Liqin Du Hui Yang Yunlong Huo | 2012 | 7:112-1142012，7，： | 1 |
| 16 | Breeding of a New Clubroot-resistant Chinese Cabbage Variety, CCR11242显示文摘In this study,using Japanese radish cytoplasmic sterile line ' Half Green Cabbage'( HGC) and clubroot-resistant South Korean cabbage variety ' CR Cabbage King'( CCK) as experimental materials,self-incompatible DH lines were obtained by microspore culture.Through five generations of backcross,CCR11239,a clubroot-resistant radish cytoplasmic sterile line,was obtained.Through six generations of self-crossing,CCR11240,the maintainer line of CCR11239,was bred.After the cross of CCK and Luchunbai 1( 83- 1) and five generations of self-crossing,self-compatible line CCR11241 was obtained.Through crossing CCR11240 with CCR11241,the new cabbage variety CCR11242 was obtained.After variety comparison test,provincial regional test and production demonstration test,the new variety was registered in 2012.The average yield of CCR11242 reached 60 975 kg / hm2,which was improved by 142% compared with Luchunbai 1( 83- 1).The disease index of CCR11242 was 5.63,which was 88.13 lower than the control,indicating high resistance( HR) to clubroot. | Xuezhong XU Zhimei TIAN Hongli YANG Jingfeng HU Liqin ZHANG Mei LAN Hongju DUAN Jiangming HE | 2016 | Agricultural Biotechnology2016，5，5： | 1 |
| 17 | Reticulon 3 attenuates the clearance of cytosolie prion aggregates via inhibiting au- tophagy显示文摘 | Chert Rui Jin Rui Wu Lu Ye Xiaofei Yang Yi Luo Kan Wang Wenxi Wu Di Ye Xing Huang Liqin Huang Tao Xiao Gengfu | 2011 | Autophagy2011，7，2： | 1 |
| 18 | Hydrogen storage properties of Mg76Ti12Fe12-xNix (x = 0, 4,8, 12) alloys by mechanical alloying显示文摘 | Guo Jin Yang Kun Xu Liqin | 2007 | Int J Hydr Energy2007，32，13： | 1 |
| 19 | Low rate of pre-exposure prophylaxis and post-exposure prophylaxis uptake and high prevalence of transmitted drug resistance among newly diagnosed primary HIV infections in Shenzhen, China: a real-world retrospective study显示文摘Background: Understanding the characteristics of newly diagnosed primary human deficiency virus-1 (HIV-1) infection in the context of the post-antiretroviral therapy era and HIV drug prophylaxis is essential for achieving the new target of 95-95-95-95 by 2025. This study reported the characteristics of newly diagnosed primary HIV-1 infection in Shenzhen.Methods: This is a real-world retrospective study. Eighty-seven newly diagnosed primary HIV-1-infected patients were recruited from January 2021 to March 2022 at the Third People’s Hospital of Shenzhen. Demographic, epidemiological, diagnostic, drug resistance, and medical data were described and analyzed.Results: Overall, 96.6% (84/87) of the newly identified primary HIV-1-infected patients were male, including 88.5% (77/87) men have sex with men (MSM), with a median age of 29.0 years (Q_(1)-Q_(3): 24.0-34.0 years);of these, 85.1% (74/87) reported high-risk sexual behaviors with casual partners. The rate of condom usage was only 28.7% (25/87). The overall rate of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) was 8.0% (7/87, including 4 PrEP and 3 PEP cases) around the potential exposure, although 41.4% of the patients had prior awareness of such interventions. Moreover, only 19.5% (17/87) had previously used PrEP or PEP. Of those, 58.8% (10/17) of the patients obtained drugs from the internet, and only 35.3% (6/17) reported good compliance. A total of 54.0% (47/87) of subjects were diagnosed by the HIV nucleic acid test. Acute retroviral syndrome appeared in 54.0% (47/87) of patients. The prevalence of transmitted drug resistance (TDR) mutation was 33.9% (19/56), including 6 (10.7%) against nucleoside reverse transcriptase inhibitor (NRTI) plus non-nucleoside reverse transcriptase inhibitor (NNRTI), 8 (14.3%) against NNRTI, and 5 (8.9%) against protease inhibitor (PI) only.Conclusions: Owing to the low utilization rate and incorrect usage of PrEP and PEP, massive efforts are needed to promote HIV-preventive strategies in the MSM population. The extremely high prevalence of TDR mutation in this population implies the need for future pretreatment drug resistance surveillance. | Qiaoli Peng Xiaoning Liu Xian Tang Qiuyue Zhang Jin Zhao Chenli Zheng Fang Zhao Yang Zhou Lukun Zhang Liqin Sun Haitao Zhang Xinyun Jia Ying Song Tingzhi Cao Siyuan Wang Man Rao Zhiwei Chen Hui Wang Yun He | 2022 | Chinese Medical Journal2022，135，22： | 1 |
| 20 | On Treatment Patterns for Modeling Medical Treatment Processes in Clinical Practice Guidelines显示文摘Clinical practice guidelines(CPGs)contain evidence-based and economically reasonable medical treatment processes.Executable medical treatment processes in healthcare information systems can assist the treatment processes.To this end,business process modeling technologies have been exploited to model medical treatment processes.However,medical treatment processes are usually flexible and knowledge-intensive.To reduce the effort in modeling,we summarize several treatment patterns(i.e.,frequent behaviors in medical treatment processes in CPGs),and represent them by three process modeling languages(i.e.,BPMN,DMN,and CMMN).Based on the summarized treatment patterns,we propose a pattern-based integrated framework for modeling medical treatment processes.A modeling platform is implemented to support the use of treatment patterns,by which the feasibility of our approach is validated.An empirical analysis is discussed based on the coverage rates of treatment patterns.Feedback from interviewed physicians in a Chinese hospital shows that executable medical treatment processes of CPGs provide a convenient way to obtain guidance,thus assisting daily work for medical workers. | Liqin Yang Liang Zhang | 2021 | China Communications2021，18，11： | 1 |
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