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| 1 | The Interaction of Population,Industry and Land in Process of Urbanization in China:A Case Study in Jilin Province显示文摘Urbanization is a complex process that covers a wide range of topics, of which population, industry and land urbanization are three important aspects. Jilin Province is an important agricultural province in China. The contradiction between population, industry and land urbanization is especially prominent here, and its coupling development is of great practical significance. In this paper, the coupling degree of population-industry-land urbanization in Jilin Province in 1990, 2000 and 2010 is measured by coupling mode. The spatial pattern of the coupling degree is analyzed by trend surface analysis and global and local spatial autocorrelation. The influence factors and their spatial differentiation are discussed using multiple linear regression(MLR) model and geographic weighted regression(GWR) model. The results show that: 1) the coupling degree of population-industry-land urbanization in Jilin Province is at a low level. Judging from the change of time scale, the urbanization of most research units is becoming more and more coordinated. From the comparison of spatial scales, there is significant spatial difference in the research units of different administrative levels. 2) Judging from the global change trend, the coupling degree of population-industry-land urbanization in the central region is higher than that in western and eastern regions. The coordination of urbanization in the central region is relatively good, and the distribution of the cold and hot spots is basically the same as that overall. 3) The spatial pattern of the coupling degree is related to the cold and hot spot distribution of the influence coefficient of urban population density and per capita urban construction land. The variation of the coupling degree spatial pattern is synchronous with the spatial change of the urban population density influence coefficient. 4) The degree of agglomeration of the urban population is the main factor promoting the coupling pattern of population-industry-land urbanization in Jilin Province, and the extent of its influence is gradually increasing. In addition, the level of city administrative, the efficiency of urban expansion and the capacity of market consumption also have an important influence on the coupling pattern. | LIU Yanjun ZHOU Guolei LIU Degang YU Huisheng ZHU Liyuan ZHANG Jing | 2018 | Chinese Geographical Science2018，28，3： | 12 |
| 2 | Qingnaoyizhi decoction suppresses the formation of glial fibrillary acidic protein-positive cells in cultured neural stem cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway显示文摘OBJECTIVE: Inactivation of the Janus kinase 2(JAK2)/signal transducer and activator of transcription 3(STAT3) signaling axis plays a crucial role in determining the fate of neural stem cells(NSCs).Qingnaoyizhi decoction(QNYZD) has been used for the treatment of vascular dementia and has shown to improve synaptic remodeling. The aim of this study was to evaluate the effect of cerebrospinal fluid(CSF) containing QNYZD(CSF-QNYZD) on the differentiation of cultured NSCs and the involvement of the JAK2/STAT3 pathway.METHODS: The protein expression levels of glial fibrillary acidic protein(GFAP), tubulin, drosophila mothers against decapentaplegic protein(SMAD-1), STAT3, and phosphorylated-STAT3 were detected by western immunoblot analysis in the groups: control, CSF, JAK/STAT inhibitor(AG490),CSF-QNYZD, and CSF-XDZ(CSF-Xidezhen). The differentiation of NSCs was determined by immunofluorescence staining. The proliferation of NSCs was measured using the Cell Counting Kit-8 proliferation assay.RESULTS: Compared with the control group,CSF-QNYZD and AG490 significantly increased the number and expression of tubulin-positive cells, reduced the number and expression of GFAP-positive cells, and down-regulated the expression of p-STAT3. However, CSF-QNYZD also decreased the expression of SMAD-1 and STAT3.CONCLUSION: Enhanced neuronal differentiation may be associated with the down-regulation of glial differentiation instead of promoting proliferationin treated NSCs. Furthermore, QNYZD may play a direct role in suppressing the formation of GFAP-positive cells and enhancing neuronal differentiation by inhibiting JAK2/STAT3 activation. Overall, these results provide insights into the possible mechanism underlying QNYZD-mediated neurogenesis. | Wu Yanqing Jing Zhiwei Qin Xiude Zhou Zhen Wang Kai Song Wanshan Wang Xueyan Hou Mengmeng Zhang Yulian Kang Liyuan | 2015 | Journal of Traditional Chinese Medicine2015，35，1： | 11 |
| 3 | Features of colorectal cancer in China stratified by anatomic sites:A hospital-based study conducted in university-affiliated hospitals from 2014 to 2018显示文摘Objective:The clinical and biological characteristics of colorectal cancer have been found to differ depending on the anatomic site of the cancer.However,for Chinese patients,there is limited information on the proportion of cases at each site and the related features.In this study,we explored the location,distribution and other features of colorectal cancers at each anatomic site in Chinese patients.Methods:We conducted a hospital-based study using hospitalization summary reports from 10 Peking University-affiliated hospitals from 2014 to 2018;the reports covered a total of 2,097,347 hospitalizations.Incident cases were chosen as the study population,and their epidemiological features were further analyzed.Results:A total of 20,739 colorectal cancer patients were identified.Rectum was the most common location(48.3%)of the cancer,whereas the proportions of patients with distal and proximal colon cancer were 24.5%and18.6%,respectively.Patients with rectal cancer were predominantly male and were the youngest for all anatomical sites(each P<0.001).The highest proportion of emergency admissions,the longest hospital stays and the highest hospitalization costs were found in patients with proximal colon cancer(each P<0.001).The proximal colon cancer subgroup included the highest proportions of patients with medical histories of cholecystectomy,cholecystolithiasis and/or gallbladder polyps and appendectomy(P=0.009,P<0.001 and P<0.001,respectively).The distal colon cancer subgroup included the highest proportions of patients with medical histories of diabetes and hypertension(P<0.001,respectively).Conclusions:The patterns of colorectal cancer observed in this study differ from those reported for Western patients and show a significantly higher proportion of patients with rectal cancer.Different epidemiological features were also found based on anatomic sites.Further studies based on tumor location should be conducted to facilitate more accurate screening and treatment. | Ruize Qu Yanpeng Ma Liyuan Tao Xiaoyuan Bao Xin Zhou Bingyan Wang Fei Li Siyi Lu Lin Tuo Siyan Zhan Zhipeng Zhang Wei Fu | 2021 | Chinese Journal of Cancer Research2021，33，4： | 10 |
| 4 | Relationship with spatial memory in diabetic rats and protein kinase Cγ,caveolin-1 in the hippocampus and neuroprotective effect of catalpol显示文摘 | Zhou Haicheng Liu Jing Ren Liyuan Liu Wei Xing Qian Men Lili Song Guirong Du Jianling | 2014 | Chinese Medical Journal2014，，5： | 7 |
| 5 | Chimeric antigen receptor T (CAR-T) cells expanded with IL-7/IL-15 mediate superior antitumor effects显示文摘Dear Editor,Genetic engineering of T cells to express chimeric antigen receptors(CARs)is an efficient approach for clinical therapy of hematological malignancies(Kuwana et al.,1987;Eshhar et al.,1993;Barrett et al.,2014).The CARs endow T cells with the ability to recognize specific antigens and bind them in an MHC-independent mariner,thereby overcoming some of the mechanisms that mediate tumor immune escape.In addition,by providing co-stimulatory signals,CARs endow T cells with enhanced cytotoxicity and persistence compared with primary T cells.A typical CAR comprises a single-chain variable frag me nt(scFv)derived from a monoclonal an tibody(mAb)for an tige n recog nition and signaling domains for co?activation(Eshhar et al.,1993;Sadelain et al.,2013). | Jianxia Zhou Liyuan Jin Fuping Wang Yuan Zhang Bing Liu Tongbiao Zhao | 2019 | Protein & Cell2019，10，10： | 7 |
| 6 | Geochemical Characteristics and Origin of Natural Gases in the Qaidam Basin,China显示文摘Sixty-five natural gas samples were collected from 19 oil-gasfields in the Qaidam basin, China. The chemical composition and carbon isotope values of the samples were measured, and the geochemical characteristics and origin of the natural gases were studied. The gases can be divided into biogenic gases, sapropelic oil-type gases, mixed type oil-type gases, coal-type gases and mixed gas. The δ13C1 values of the biogenic gases are very small and the C2+ contents of them are very low, ranging from -68.2‰ to -61.8‰ and 0.06% to 0.20% respectively. They have heavy δD and δ13CCO2, showing a CO2 reduction pathway. They are distributed in the East depression region and derived from the Quaternary source rocks. The sapropelic oil-type gases have small δ13C2 values and high C2+ ranging from -36.6‰ to -28.6‰ and from 33.01% to 47.15% respectively. The mixed type oil-type gases have δ13C2 values and C2+ contents varying from -28.6‰ to -24.8‰ and from 4.81% to 26.06% respectively. Both sapropelic oil-type gases and mixed type oil-type gases are associated with oil-type oils, distributed in the West depression region and derived from the Tertiary saltwater lacustrine sapropelic source rocks and humic source rocks respectively. The δ13C2 values of the coal-type gases are extremely high and the C2+ contents are very low, changing from -23.3‰ to -12.5‰ and from 0.06% to 18.07% respectively. The coal-type gases in the Nanbaxian gasfield and the Lenghu oil-gasfields in the North fault block belt are derived from the Middle Jurassic coal-measures source rocks, whereas those in the West depression region are derived from the Tertiary saltwater lacustrine humic source rocks. Compared with some other basins in China, the natural gases there have obviously heavier δ13C due to the heavier δ13C of different types of kerogens of the Tertiary saltwater lacustrine source rocks in the West depression region of the basin. The mixing of natural gases is common in the West depression region, but the mixed gases are formed by sapropelic oil-type gases, mixed type oil-type gases or coal-type gases, respectively, of different levels of maturity. Most of the sapropelic oil-type gases and mixed type oil-type gases in the west part are thermally immature and low-mature, but the coal-type gases in the West depression region and the North fault block belt are mature and high- to over-mature. | ZHANG Xiaobao, HU Yong, DUAN Yi, MA Liyuan, MENG Zifang, HE Peng,ZHOU Shixin and PENG DehuaState Key Laboratory of Gas Geochemistry, Lanzhou Institute of Geology, Chinese Academy ofSciences, Lanzhou, Gansu 730000 Research Institute of Petroleum Exploration and Development, Qinghai Petroleum Company,CNPC, Dunhuang, Gansu 736200 | 2003 | Acta Geologica Sinica(English Edition)2003，77，1： | 6 |
| 7 | Upregulation of annexin A5 affects the biological behaviors of lung squamous carcinoma cells in vitro显示文摘Annexin A5 is a Ca2?-dependent phospholipidbinding protein and protein kinase C inhibitory protein. It has a potential role in cellular signal transduction, inflammation, growth and differentiation. In this study, we evaluated the expression of this protein in lung tumor tissues and subsequently established a NCI-H520 cell line that stably expresses the wild-type ANXA5 gene to determine the effects of annexin A5 upregulation on the cell morphology, proliferation and metastasis potential in vitro.The effects of annexin A5 on NCI-H520 cells were tested by crystal violet staining, CCK-8 assay, scratch wound assay, and Transwell assay. The expressions of Akt,PCNA, vimentin, and E-cadherin were examined by Western blot assay. In this study, we demonstrated that annexin A5 is expressed at lower levels in tumor tissues compared with normal tissues. Additionally, the upregulation of this protein may inhibit the proliferation, migration, and invasion abilities of NCI-H520 cells in vitro. The transfected cells were arrested in the G1/S phase of the cell cycle, and the expression levels of Akt, PCNA and Vimentin were downregulated, while E-cadherin was upregulated. | Linlin Gong Haoqi Zhao Lan Wang Bing Sun Lijun Yu Xiaoyu Qi Xin Zhou Liyuan Zhang Hongwei Guan Shujuan Shao | 2014 | Chinese Science Bulletin2014，59，28： | 6 |
| 8 | Adipocyte-derived SFRP5 inhibits breast cancer cells migration and invasion through Wnt and epithelial-mesenchymal transition signaling pathways显示文摘Objective:Obesity is closely associated with metastasis in breast cancer patients.Secreted frizzled-related protein 5(SFRP5),one of the novel adipokines with anti-inflammatory properties,is associated with obesity.This study aims to study the role of SFRP5 in the crosstalk between obesity and breast cancer metastasis and identify the underlying mechanism.Methods:3T3-L1 pre-adipocytes were differentiated to mature adipocytes and a hypertrophic adipocyte model was induced with palmitic acid(PA).Cell motility was measured in MDA-MB-231 and MCF-7 breast cancer cells co-cultured with adipocytes conditioned medium(CM)with or without SFRP5 protein.Wnt and epithelialmesenchymal transition(EMT)signal pathways were investigated by western blot.Circulating SFRP5 level in 218 breast cancer patients and the association with clinicopathologic characteristics of breast cancer were further determined.Online databases ENCORI and PREDICT Plus were used to exam the link between SFRP5 and prognosis.Results:Reduced SFRP5 level was detected in the hypertrophic adipocyte model.Recombinant SFRP5 protein inhibited MDA-MB-231 and MCF-7 cells invasion and migration induced by PA-treated adipocyte CM,and SFRP5 inhibition by specific antibody reversed the effect of SFRP5.Furthermore,SFRP5 significantly inhibited Wnt and downstream EMT in breast cancer cells.Low circulating SFRP5 level correlated with body mass index(BMI),lymph node(LN)metastasis,TNM stage and high Ki67 expression in breast cancer patients.Increased SFRP5 level was associated with favorable predicted survival.Kaplan-Meier curves showed high SFRP5 level in tumor tissue was associated with better outcome of breast cancer patients.Conclusions:Our findings demonstrated SFRP5 is a vital adipokine that mediates the crosslink between obesity and the metastatic potential of breast cancer.Promotion of SFRP5 expression in the adipose microenvironment may represent a novel approach for preventing breast cancer metastasis. | Wenzhong Zhou Chunmiao Ye Liang Li Liyuan Liu Fei Wang Lixiang Yu Fei Zhou Yujuan Xiang Yongjiu Wang Gengshen Yin Zhongbing Ma Qinye Fu Qiang Zhang Dezong Gao Shuya Huang Zhigang Yu | 2020 | Chinese Journal of Cancer Research2020，32，3： | 5 |
| 9 | Measurement and simulation of swirling coal combustion显示文摘Particle image velocimetry(PIV),thermocouples and flue gas analyzer are used to study swirling coal combustion and NO formation under different secondary-air ratios.Eulerian-Lagrangian large-eddy simulation(LES)using the Smagorinsky-Lilly sub-grid scale stress model,presumed-PDF fast chemistry and eddy-break-up(EBU)gas combustion models,particle devolatilization and particle combustion models,are simultaneously used to simulate swirling coal combustion.Statistical LES results are validated by measurement results.Instantaneous LES results show that the coherent structures for swirling coal combustion are stronger than those for swirling gas combustion.Particles are shown to concentrate along the periphery of the coherent structures.Combustion flame is located in the high vorticity and high particle concentration zones.Measurement shows that secondary-air ratios have little effect on final NO formation at the exit of the combustor. | Liyuan Hu Lixing Zhou Yonghao Luo Caisong Xu | 2013 | Particuology2013，11，2： | 5 |
| 10 | Mapping epistasis and environment × QTX interaction based on four-omics genotypes for the detected QTX loci controlling complex traits in tobacco显示文摘Using newly developed methods and software, association mapping was conducted for chromium content and total sugar in tobacco leaf, based on four-omics datasets. Our objective was to collect data on genotype and phenotype for 60 leaf samples at four developmental stages, from three plant architectural positions and for three cultivars that were grown in two locations. Association mapping was conducted to detect genetic variants at quantitative trait SNP(QTS) loci, quantitative trait transcript(QTT) differences,quantitative trait protein(QTP) variability, and quantitative trait metabolite(QTM) changes,which can be summarized as QTX locus variation. The total heritabilities of the four-omics loci for both traits tested were 23.60% for epistasis and 15.26% for treatment interaction.Epistasis and environment × treatment interaction had important impacts on complex traits at all-omics levels. For decreasing chromium content and increasing total sugar in tobacco leaf, six methylated loci can be directly used for marker-assisted selection, and expression of ten QTTs, seven QTPs and six QTMs can be modified by selection or cultivation. | Liyuan Zhou Ruiyuan Li Longjiang Fan Yuewei Shi Zhihong Wang Shengdong Xie Yijie Gui Xueliang Ren Jun Zhu | 2013 | The Crop Journal2013，1，2： | 4 |
| 11 | Large-eddy structures of turbulent swirling flows and methane-air swirling diffusion combustion显示文摘Turbulent swirling flows and methane-air swirling diffusion combustion are studied by large-eddy simulation (LES) using a Smagorinsky-Lilly subgrid scale turbulence model and a second-order moment (SOM) SGS combustion model, and also by RANS modeling using the Reynolds Stress equation model with the IPCM+wall and IPCM pressure-strain models and SOM combustion model. The LES statistical results for swirling flows give good agreement with the experimental results, indicating that the adopted subgrid-scale turbulence model is suitable for swirling flows.The LES instantaneous results show the complex vortex shedding pattern in swirling flows. The initially formed large vortex structures soon break up in swirling flows. The LES statistical results of combustion modeling are near the experimental results and are as good as the RANS-SOM modeling results. The LES results show that the size and range of large vortex structures in swirling combustion are different from those of isothermal swirling flows, and the chemical reaction is intensified by the large-eddy vortex structures. | Liyuan Hu Lixing Zhou Jian Zhang | 2005 | Acta Mechanica Sinica2005，21，5： | 4 |
| 12 | Wear properties of NiAl based materials | Jianting Guo Zhensheng Wang Liyuan Sheng Lanzhang Zhou Chao Yuan Zhigang Chen Li Song | 2012 | Progress in Natural Science:Materials International2012，22，5： | 3 |
| 13 | Immobilized nickel(Ⅱ) on organic-inorganic hybrid materials: The effective and reusable catalysts for Biginelli reaction显示文摘The immobilized nickel(II) on the organic-inorganic hybrid material was prepared and used as an effective catalyst for the Biginelli reaction.In the presence of the immobilized nickel catalyst,aromatic aldehydes reacted with ethyl acetoacetate and urea (or thiourea) smoothly to generate the corresponding Biginelli products in good to excellent yields without using any additive.The work-up procedure is very simple and practical.Furthermore,the silica-supported nickel(II) could be recovered and recycled for six consecutive trials without significant loss of its catalytic activity. | ZHANG LiYuan WANG ChuanHu ZHOU Li LI PinHua ZHANG XiuLi WANG Lei | 2011 | Science China Chemistry2011，54，1： | 3 |
| 14 | High-risk phenotypes of genetic disease in a Neonatal Intensive Care Unit population显示文摘To the Editor: Genetic diseases contribute to 35% of deaths during the first year of life and are a significant cause of intensive care.[1] A previous study based on the China Neonatal Genomes Project investigated the genetic causes of early infant deaths and found that >25% of deceased neonates with genetic diagnoses can be cured if diagnosed in time.[2] Therefore, it is crucial to target and diagnose neonates with genetic diseases as early as possible. According to our experience, the typical phenotypes, such as special facial features or multiple congenital anomalies (MCAs), indicate a high risk of genetic disease and lead physicians to perform genetic testing in neonates as early as possible. However, in practice, infants without typical phenotypes typically undergo a long and costly diagnostic process before genetic diagnoses are confirmed. Moreover, a recent survey by the American College of Medical Genetics and Genomics (ACMG) and other national professional organizations indicated that there are insufficient numbers of qualified geneticists to fulfil genetic service needs.[3] The ACMG published the general clinical features for genetic testing indications. For example, patients with phenotypes or family history data that strongly implicate a genetic cause may undergo genetic testing.[1] However, the study indicated that many genetic conditions arise de novo or are inherited with no family history.[1] A previous study attempted to apply the non-phenotype-driven panel approach in neonates admitted to the neonate intensive care unit (NICU).[4] However, at present, the diagnostic yield is only 3.45% (1/29).[4] In addition, the economic and ethical issues associated with genomic screening remain challenging. Therefore, the available indications for genetic testing may improve the management of genetic diseases. | Tiantian Xiao Qi Ni Huiyao Chen Huijun Wang Lin Yang Bingbing Wu Yun Cao Guoqiang Cheng Laishuan Wang Liyuan Hu Hongfang Mei Yulan Lu Mengchun Gong Xinran Dong Wenhao Zhou | 2022 | Chinese Medical Journal2022，，5： | 2 |
| 15 | The Main Progress of Perovskite Solar Cells in 2020-2021显示文摘Perovskite solar cells(PSCs)emerging as a promising photovoltaic technology with high efficiency and low manufacturing cost have attracted the attention from all over the world.Both the efficiency and stability of PSCs have increased steadily in recent years,and the research on reducing lead leakage and developing eco-friendly lead-free perovskites pushes forward the commercialization of PSCs step by step.This review summarizes the main progress of PSCs in 2020 and 2021 from the aspects of efficiency,stability,perovskite-based tandem devices,and lead-free PSCs.Moreover,a brief discussion on the development of PSC modules and its challenges toward practical application is provided. | Tianhao Wu Zhenzhen Qin Yanbo Wang Yongzhen Wu Wei Chen Shufang Zhang Molang Cai Songyuan Dai Jing Zhang Jian Liu Zhongmin Zhou Xiao Liu Hiroshi Segawa Hairen Tan Qunwei Tang Junfeng Fang Yaowen Li Liming Ding Zhijun Ning Yabing Qi Yiqiang Zhang Liyuan Han | 2021 | Nano-Micro Letters2021，13，10： | 2 |
| 16 | Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis显示文摘 | Wei Li Baoyang Hu XuepengWang Tianda Li Tongtong Cui Dawei Yu Chao Liu Liyuan Jiang Guihai Feng Lei wang Rui Fu Xinxin Zhang Jie Hao Yukai Wang Liu Wang Qi Zhou | 2018 | Cell Research2018，28，1： | 2 |
| 17 | Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditis elegans显示文摘Arginine catabolism involves enzyme-dependent reactions in both mitochondria and the cytosol,defects in which may lead to hyperargininemia,a devastating developmental disorder.It is largely unknown if defective arginine catabolism has any effects on mitochondria.Here we report that normal arginine catabolism is essential for mitochondrial homeostasis in Caenorhabditis elegans.Mutations of the arginase gene argn-1 lead to abnormal mitochondrial enlargement and reduced adenosine triphosphate(ATP)production in C elegans hypodermal cells.ARGN-1 localizes to mitochondria and its loss causes arginine accumulation,which disrupts mitochondrial dynamics.Heterologous expression of human ARGl or ARG2 rescued the mitochondrial defects of argn-1 mutants.Importantly,genetic inactivation of the mitochondrial basic amino acid transporter SLC-25A29 or the mitochondrial glutamate transporter SLC-25A18.1 fully suppressed the mitochondrial defects caused by argn-1 mutations.These findings suggest that mitochondrial damage probably contributes to the pathogenesis of hyperargininemia and provide clues for developing therapeutic treatments for hyperargininemia. | Ruofeng Tang Xin Wang Junxiang Zhou Fengxia Zhang Shan Zhao Qiwen Gan Liyuan Zhao Fengyang Wang Qian Zhang Jie Zhang Guodong Wang Chonglin Yang | 2020 | Journal of Genetics and Genomics2020，47，3： | 2 |
| 18 | Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma显示文摘Pancreatic ductal adenocarcinoma(PDAC)is characterized by the highest mortality among carcinomas.The pathogenesis of PDAC requires elevated autophagy,inhibition of which using hydroxychloroquine has shown promise.However,current realization is impeded by its suboptimal use and unpredictable toxicity.Attempts to identify novel autophagy-modulating agents from already approved drugs offer a rapid and accessible approach.Here,using a patient-derived organoid model,we performed a comparative analysis of therapeutic responses among various antimalarial/fungal/parasitic/viral agents,through which econazole(ECON),an antifungal compound,emerged as the top candidate.Further testing in cell-line and xenograft models of PDAC validated this activity,which occurred as a direct consequence of dysfunctional autophagy.More specifically,ECON boosted autophagy initiation but blocked lysosome biogenesis.RNA sequencing analysis revealed that this autophagic induction was largely attributed to the altered expression of activation transcription factor 3(ATF3).Increased nuclear import of ATF3 and its transcriptional repression of inhibitor of differentiation-1(ID-1)led to inactivation of the AKT/mammalian target of rapamycin(m TOR)pathway,thus giving rise to autophagosome accumulation in PDAC cells.The magnitude of the increase in autophagosomes was sufficient to elicit ER stress-mediated apoptosis.Furthermore,ECON,as an autophagy inhibitor,exhibited synergistic effects with trametinib on PDAC.This study provides direct preclinical and experimental evidence for the therapeutic efficacy of ECON in PDAC treatment and reveals a mechanism whereby ECON inhibits PDAC growth. | Ningna Weng Siyuan Qin Jiayang Liu Xing Huang Jingwen Jiang Li Zhou Zhe Zhang Na Xie Kui Wang Ping Jin Maochao Luo Liyuan Peng Edouard C.Nice Ajay Goel Suxia Han Canhua Huang Qing Zhu | 2022 | Acta Pharmaceutica Sinica B2022，12，7： | 2 |
| 19 | Supported Cu catalysts for the selective hydrogenolysis of glycerol to propanediols显示文摘 | Guo Liyuan Zhou Jinxia Mao Jingbo | 2009 | Applied Catalysis A:General2009，367，： | 1 |
| 20 | Studies on strongly swirling flows in the full space of a volute cyclone separator显示文摘 | HU Liyuan ZHOU Lixing ZHANG Jian | 2005 | AIChE Journal2005，51，3： | 1 |
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