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| 1 | Advantage of autologous blood transfusion in surgery for hepatocellular carcinoma显示文摘AIM: To evaluate the significance of autologous blood transfusion (AT) in reducing homologous blood transfusion (HT) in surgery for hepatocellular carcinoma (HCC). METHODS: The proportion of patients who received HT was compared between two groups determined by the time of AT introduction; period A (1991-1994, n = 93) and period B (1995-2000, n = 201). Multivariate logistic regression analysis was performed in order to identify independent significant predictors of the need for HT. We also investigated the impact of AT and HT on long-term postoperative outcome after curative surgery for HCC. RESULTS: The proportion of patients with HT was significantly lower in period B than period A (18.9% vs 60.2%, P < 0.0001). Multivariate logistic regression analysis identified AT administration as a significant independent predictor of the need for HT (P < 0.0001). Disease-free survival in patients with AT was comparable to that without any transfusion. Multivariate analysis identified HT administration as an independent significant factor for poorer disease-free survival (P = 0.0380). CONCLUSION: AT administration significantly decreased the need for HT. Considering the postoperative survival disadvantage of HT, AT administration could improve the long-term outcome of HCC patients. | Yoshito Tomimaru Hidetoshi Eguchi Shigeru Marubashi Hiroshi Wada Shogo Kobayashi Masahiro Tanemura Koji Umeshita Yuichiro Doki Masaki Mori Hiroaki Nagano | 2011 | World Journal of Gastroenterology2011，17，32： | 8 |
| 2 | Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava显示文摘Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). The SEF of the liver was successfully resected, and the infiltrated IVC was also removed together with the liver tumor. Histopathological examination of the tumor showed typical histopathology of SEF. Immunohistochemically, the tumor was positive for vimentin. Recurrence was noted 7 mo after surgery. After chemotherapy, the recurrent tumor was resected surgically, and histopathological examination showed similar findingsto those of the primary tumor. To our knowledge, this is the first report of SEF of the liver with tumor invasion of the IVC. | Yoshito Tomimaru Hiroaki Nagano Shigeru Marubashi Shogo Kobayashi Hidetoshi Eguchi Yutaka Takeda Masahiro Tanemura Toru Kitagawa Koji Umeshita Nobuyuki Hashimoto Hideki Yoshikawa Kenichi Wakasa Yuichiro Doki Masaki Mori | 2009 | World Journal of Gastroenterology2009，15，33： | 5 |
| 3 | Fresh frozen plasma transfusion does not affect outcomes following hepatic resection for hepatocellular carcinoma显示文摘AIM:To investigate whether fresh frozen plasma (FFP) transfusion affects outcomes following hepatic resection for hepatocellular carcinoma (HCC) in terms of liver function,postoperative complications and cancer prognosis.METHODS:We retrospectively compared the incidence of postoperative complications between 204 patients who underwent hepatectomy for HCC with routine FFP transfusion in an early period (1983-1993,Group A) and 293 with necessity for FFP transfusion during a later period (1998-2006,Group B),and also between two subgroups of Group B [22 patients with FFP transfusion (Group B1) and 275 patients without FFP transfusion (Group B2)].Additionally,only in limited patients in Group B1 and Group B2 with intraoperative blood loss≥ 2000 mL (Group B1 ≥ 2000 mL and Group B2 ≥ 2000 mL),postoperative complications,liver function tests,and cancer prognosis were compared.RESULTS:No mortality was registered in Group B,compared to 8 patients (3.9%) of Group A.The incidence of morbidity in Group B2 [23.2% (64/275)] was not significantly different from Group B1 [40.9% (9/22)] and Group A [27.0% (55/204)].The incidence of complications and postoperative liver function tests were comparable between Group B1 ≥ 2000 mL vs Group B2 ≥ 2000 mL.Postoperative prognosis did not correlate with administration of FFP,but with tumor-related factors.CONCLUSION:The outcome of hepatectomy for HCC is not influenced by FFP transfusion.We suggest FFP transfusion be abandoned in patients who undergo hepatectomy for HCC. | Yoshito Tomimaru Hiroshi Wada Shigeru Marubashi Shogo Kobayashi Hidetoshi Eguchi Yutaka Takeda Masahiro Tanemura Takehiro Noda Koji Umeshita Yuichiro Doki Masaki Mori Hiroak Nagano | 2010 | World Journal of Gastroenterology2010，16，44： | 5 |
| 4 | Preoperative Gemcitabine-Based Chemoradiation Therapy for Resectable and Borderline Resectable Pancreatic Cancer显示文摘 | Hidenori Takahashi Hiroaki Ohigashi Kunihito Gotoh Shigeru Marubashi Terumasa Yamada Masayuki Murata Tatsuya Ioka Hiroyuki Uehara Masahiko Yano Osamu Ishikawa | 2013 | Annals of Surgery2013，，6： | 3 |
| 5 | Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma显示文摘 | Yoshito Tomimaru Hidetoshi Eguchi Hiroaki Nagano Hiroshi Wada Shogo Kobayashi Shigeru Marubashi Masahiro Tanemura Akira Tomokuni Ichiro Takemasa Koji Umeshita Tatsuya Kanto Yuichiro Doki Masaki Mori | 2011 | Journal of Hepatology2011，，1： | 3 |
| 6 | Hepatic Artery Reconstruction in Living Donor Liver Transplantation: Risk Factor Analysis of Complication and a Role of MDCT Scan for Detecting Anastomotic Stricture显示文摘 | Shigeru Marubashi Shogo Kobayashi Hiroshi Wada Koichi Kawamoto Hidetoshi Eguchi Yuichiro Doki Masaki Mori Hiroaki Nagano | 2013 | World Journal of Surgery2013，，11： | 3 |
| 7 | Equivalent Outcomes After Anatomical and Non-anatomical Resection of Small Hepatocellular Carcinoma in Patients with Preserved Liver Function显示文摘 | Yoshito Tomimaru Hidetoshi Eguchi Shigeru Marubashi Hiroshi Wada Shogo Kobayashi Masahiro Tanemura Koji Umeshita Yuichiro Doki Masaki Mori Hiroaki Nagano | 2012 | Digestive Diseases and Sciences2012，，7： | 2 |
| 8 | Screening for hilar biliary invasion in ampullary cancer patients显示文摘BACKGROUND The treatment for ampullary cancer is pancreatoduodenectomy or local ampullectomy.However,effective methods for the preoperative investigation of hilar biliary invasion in ampullary cancer patients have not yet been identified.AIM To determine the necessity of and an appropriate method for investigating hilar biliary invasion of ampullary cancer.METHODS Among 43 ampullary cancer patients,34 underwent endoscopic treatment(n=9)or surgery(n=25).The use of imaging findings(thickening and enhancement of the bile duct wall on contrast-enhanced computed tomography,irregularity on endoscopic retrograde cholangiography,thickening of the entire bile duct wall on intraductal ultrasonography(IDUS),and partial thickening of the bile duct wall on IDUS)and biliary biopsy results for diagnosing hilar biliary invasion of ampullary cancer was compared.RESULTS Hilar invasion was not observed in every patient.Among the patients who did not undergo biliary stent insertion,the combination of partial thickening of the bile duct wall on IDUS and biliary biopsy results showed the highest accuracy(100%)for diagnosing hilar biliary invasion.However,each imaging method and biliary biopsy yielded some false-positive results.CONCLUSION Although some false-positive results were obtained with each method,the combination of partial thickening of the bile duct wall on IDUS and biliary biopsy results was useful for diagnosing hilar biliary invasion of ampullary cancer.However,hilar invasion of ampullary cancer is rare;therefore,the investigation of hilar biliary invasion of ampullary cancer might be unnecessary. | Tadayuki Takagi Mitsuru Sugimoto Rei Suzuki Naoki Konno Hiroyuki Asama Yuki Sato Hiroki Irie Jun Nakamura Mika Takasumi Minami Hashimoto Tsunetaka Kato Ryoichiro Kobashi Takumi Yanagita Yuko Hashimoto Shigeru Marubashi Takuto Hikichi Hiromasa Ohira | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，9： | 2 |
| 9 | Steroid-free living-donor liver transplantation in adults.显示文摘 | Marubashi S Dono K Amano K | | 0，，： | 2 |
| 10 | Effect of portal hemodynamics on liver regeneration studied in a novel portohepatic shunt rat model显示文摘 | Marubashi S Sakon M Nagano H | 2004 | Surgery2004，136，5： | 1 |
| 11 | ABO-incompatible adult liver transplantation when the anti-ABO antibody titer is high显示文摘 | Shimoda M Marubashi S Dono K | 2009 | Hepatogastroenterology2009，56，93： | 1 |
| 12 | The Value of Serum Midkine Level in Diagnosis of Hepatocellular Carcinoma显示文摘 | Karim Y. A. Shaheen Abeer I. Abdel-Mageed Eslam Safwat Ashraf M. AlBreedy Shigeru Marubashi | 2015 | International Journal of Hepatology2015，，： | 1 |
| 13 | Detection of AFP mRNA-expressing cells in the peripheral blood for prediction of HCC recurrence after living donor liver transplantation显示文摘 | Marubashi S DonoK Nagano H | 2007 | Transpl Int2007，20，7： | 1 |
| 14 | Combined Transplantation of Pancreatic Islets and Adipose Tissue-Derived Stem Cells Enhances the Survival and Insulin Function of Islet Grafts in Diabetic Mice显示文摘 | Yoshiaki Ohmura Masahiro Tanemura Naomasa Kawaguchi Tomohiko Machida Tsukasa Tanida Takashi Deguchi Hiroshi Wada Shogo Kobayashi Shigeru Marubashi Hidetoshi Eguchi Yutaka Takeda Nariaki Matsuura Toshinori Ito Hiroaki Nagano Yuichiro Doki Masaki Mori | 2010 | Transplantation2010，，12： | 1 |
| 15 | Combined IFN-α and 5-FU treatment as a postoperative adjuvant followingsurgery for hepatocellular carcinoma with portal venous tumor thrombus显示文摘 | Hiroaki Nagano Shogo Kobayashi Shigeru Marubashi Hiroshi Wada Hidetoshi Eguchi Masahiro Tanemura Yoshito Tomimaru Koji Umeshita Yuichiro Doki Masaki Mori | 2013 | Experimental and Therapeutic Medicine2013，，1： | 1 |
| 16 | Hepatectomy based on the tumor hemodynamics for hepatocellular carcinoma: a comparison among the hybrid and pure laparoscopic procedures and open surgery显示文摘 | Kobayashi S Nagano H Marubashi S | 2013 | Surg Endosc2013，27，2： | 1 |
| 17 | Hepatecto- my based on the tumor hemodynamics for hepatocellular carcinoma: a comparison among the hybrid and pure laparoscopic procedures and open surgery显示文摘 | Kobayashi S Nagano H Marubashi S | 2013 | Surg En- dosc2013，27，2： | 1 |
| 18 | Prediction of the Postoperative Prognosis of Intrahepatic Cholangiocarcinoma (ICC): Importance of Preoperatively-Determined Anatomic Invasion Level and Number of Tumors显示文摘 | Shigeru Marubashi Kunihito Gotoh Hidenori Takahashi Hiroaki Ohigashi Masahiko Yano Osamu Ishikawa Masato Sakon | 2014 | Digestive Diseases and Sciences2014，，1： | 1 |
| 19 | Successful adult ABO incompatible living donor liver transplantation:experience with double infusion through the hepatic artery and portal vein显示文摘 | Kobayashi S Nagano H Marubashi S | 2011 | Hepatogastroenterology2011，58，106： | 1 |
| 20 | Circulating Tumor Cells Measurements in Hepatocellular Carcinoma显示文摘 | Franck Chiappini Shigeru Marubashi | 2012 | International Journal of Hepatology2012，，： | 1 |
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