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| 1 | Biosorption of copper and zinc by immobilised and free algal biomass,and the effects of metal biosorption on the growth and cellular structure of Chlorella sp.and Chlamydomonas sp.isolated from rivers in Penang,Malaysia显示文摘In this study,the biosorption of copper and zinc ions by Chlorella sp.and Chlamydomonas sp.isolated from local environments in Malaysia was investigated in a batch system and by microscopic analyses.Under optimal biosorption conditions,the biosorption capacity of Chlorella sp.for copper and zinc ions was 33.4 and 28.5 mg/g,respectively,after 6 hr of biosorption in an immobilised system.Batch experiments showed that the biosorption capacity of algal biomass immobilised in the form of sodium alginate beads was higher than that of the free biomass.Scanning electron microscopy and energy-dispersive X-ray spectroscopy analyses revealed that copper and zinc were mainly sorbed at the cell surface during biosorption.Exposure to 5 mg/L of copper and zinc affected both the chlorophyll content and cell count of the algal cells after the first 12 hr of contact time. | W.O.Wan Maznah A.T.Al-Fawwaz Misni Surif | 2012 | Journal of Environmental Sciences2012，24，8： | 9 |
| 2 | Edible Bird's Nest Attenuates Menopause-Related Bone Degeneration in Rats via Increasing Bone Estrogen-Receptor Expression显示文摘Objective:To investigate the mechanistic basis for the attenuation of bone degeneration by edible bird's nest(EBN)in ovariectomized rats.Methods:Forty-two female Sprage-Dawley rats were randomized into 7 groups(6 in each group).The ovariectomized(OVX)and OVX+6%,3%,and 1.5%EBN and OVX+estrogen groups were given standard rat chow alone,standard rat chow+6%,3%,and 1.5%EBN,or standard rat chow+estrogen therapy(0.2mg/kg per day),respectively.The sham-operation group was surgically opened without removing the ovaries.The control group did not have any surgical intervention.After 12 weeks of intervention,blood samples were taken for serum estrogen,osteocalcin,and osteoprotegerin,as well as the measurement of magnesium,calcium abd zinc concentrations.While femurs were removed from the surrounding muscles to measure bone mass density using the X-ray edge detection technique,then collected for histology and estrogen receptor(ER)immunohistochemistry.Results:Ovariectomy altered serum estrogen levels resulting in increased food intake and weight gain,while estrogen and EBN supplementation attenuated these changes.Ovariectomy also reduced bone ER expression and density,and the production of osteopcalcin and osteorotegerin,which are important pro-osteoplastic hormones that promote bone mineraliztion and density.Conversely,estrogen and EBN increased serum estrogen levels leading to increased bone ER expression,pro-osteoplastic hormone production and bone density(all P<0.05).Conclusion:EBN could be used as a safe alternative to hormone replacement therapys for managing menopausal complications like bone degeneration. | HOU Zhi-ping TANG Shi-ying Jl Hai-ru HE Pei-yuan LI Yu-hong DONG Xian-ling DU Meng-nan Ismail Maznah HE Wen-jing | 2021 | Chinese Journal of Integrative Medicine2021，27，4： | 6 |
| 3 | Efficient solvent extraction of antioxidant-rich extract from a tropical diatom,Chaetoceros calcitrans (Paulsen) Takano 1968显示文摘Objective: To compare the in vitro antioxidant capacity of a diatom, Chaetoceros calcitrans(C. calcitrans) extracted using six types of solvents.Methods: Each extract was evaluated in terms of extraction yield, total carotenoid,fucoxanthin content, total phenolic and antioxidant capacities(DPPH and ABTS +scavenging activity and iron chelating activity).Results: The methanol extract exhibited the highest yield [(22.71 ± 0.96) g/100 g dry weight(DW)], total carotenoid [(4.46 ± 0.36) mg/g DW], total phenolic [(2.49 ± 0.08) mg gallic acid equivalents/g DW] and second highest fucoxanthin content [(2.08 ± 0.03) mg fucoxanthin/g DW] as compared to other solvent extracts. Methanolic extract also exhibited significantly higher(P < 0.05) scavenging(DPPH, ABTS +) and iron chelating activities.Conclusions: Methanol was the recommended solvent for the production of antioxidant rich extract from C. calcitrans. Both carotenoids and phenolic acids were found to be positively correlated to the antioxidant capacities of C. calcitrans. Lead bioactives confirmed by subsequent high performance liquid chromatography studies were fucoxanthin, gallic acid and protocatechuic acid. | Su Chern Foo Fatimah Md.Yusoff Maznah Ismail Mahiran Basri Nicholas Mun Hoe Khong Kim Wei Chan Sook Kun Yau | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，10： | 2 |
| 4 | Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G 2 /M cell cycle arrest显示文摘 | Nurdin Armania Latifah Saiful Yazan Siti Noorhidayah Musa Intan Safinar Ismail Jhi Biau Foo Kim Wei Chan Husain Noreen Abdul Hamid Hisyam Said Zulfahmi Maznah Ismail | 2013 | Journal of Ethnopharmacology2013，，2： | 2 |
| 5 | Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein显示文摘 | Wei Keat Ng Latifah Saiful Yazan Maznah Ismail | 2011 | Toxicology in Vitro2011，，7： | 1 |
| 6 | Eye on teaching: improving practice through research inquiries显示文摘 | Raja Maznah Raja Hussain Aishah Abu Bakar | 2011 | Procedia - Social and Behavioral Sciences2011，，： | 1 |
| 7 | Effect of acid treatment on extractable protein,crosslink density and tensile properties of natural rubber latex films显示文摘 | Siti Maznah K Baharin I Hanafi l | 2008 | Polymer Testing2008，27，7： | 1 |
| 8 | Problem‐based learning in Asian universities显示文摘 | Raja Maznah Raja Hussain Wan Hasmah Wan Mamat Norani Salleh | 2007 | Studies in Higher Education2007，32，6： | 1 |
| 9 | Antioxidant ac- tivities of phenolic rich fractions (PRFs) obtained from black mahlab (Monechma ciliatum ) and white mahlab (Prunus ma- haleb) seedcakes显示文摘 | Abdalbasit A M Ramlah M I Maznah I | 2010 | Food Chem2010，118，： | 1 |
| 10 | In vitro Delivery and con- trolled release of Doxorubicin for targeting osteosarcoma bone cancer显示文摘 | Shafiu AK Maznah I Samer HH | 2013 | Molecules2013，18，10： | 1 |
| 11 | Persistence of fenvaerate in three Mala ysian agricultural soils显示文摘 | Ismail B S Maznah Z | 2005 | Bull Environ Contam Toxicol2005，75，4： | 1 |
| 12 | Effect of acid treatment on extractable protein content, crosslink density and tensile properties of natural rubber latex films显示文摘 | K Siti Maznah A Baharin I Hanafi | 2008 | Poly- mer Testing2008，27，7： | 1 |
| 13 | Antioxidant activity and phenolic content of phenolic rich fractions obtained from black cumin(Nigella sativa)seedcake显示文摘 | Abdalbasit A M Ramlah M I Maznah I | | 0，，01： | 1 |
| 14 | Effect of soaking in potassium hydroxide solution on the curing, tensile prop- erties and extractable protein content of natural rubber latex films显示文摘 | K Siti Maznah A Baharin I Hanafi | 2008 | Polymer Testing2008，27，8： | 1 |
| 15 | Antioxidant activity of phenolics–saponins rich fraction prepared from defatted kenaf seed meal显示文摘 | Kim Wei Chan Shahid Iqbal Nicholas M.H. Khong Der-Jiun Ooi Maznah Ismail | 2014 | LWT - Food Science and Technology2014，，1： | 1 |
| 16 | Defatted kenaf seed meal (DKSM): Prospective edible flour from agricultural waste with high antioxidant activity显示文摘 | Kim Wei Chan Nicholas M.H. Khong Shahid Iqbal Siti Muskinah Mansor Maznah Ismail | 2013 | LWT - Food Science and Technology2013，，1： | 1 |
| 17 | Kenaf seed supercritical fluid extract reduces aberrant crypt foci formation in azoxymethane-induced rats显示文摘 | Siti Aisyah Abd Ghafar Latifah Saiful Yazan Paridah Md Tahir Maznah Ismail | 2010 | Experimental and Toxicologic Pathology2010，，3： | 1 |
| 18 | Antioxidant activity and phenolic content of phenolic rich fractions obtained from black cumin (Nigella sativa) seedcake显示文摘 | Mariod A A Ramlah M I Maznah I | | 0，，01： | 1 |
| 19 | Frontal subcortical ischemia is crucial for post stroke cognitive impairment显示文摘 | Nagaendran Kandiah Lynn Wiryasaputra Kaavya Narasimhalu Amit Karandikar Maznah Marmin Esther Vanessa Chua Yih-Yian Sitoh | 2011 | Journal of the Neurological Sciences2011，，1： | 1 |
| 20 | Supercritical carbon dioxide fluid extraction of Hibiscus cannabinus L. seed oil: A potential solvent-free and high antioxidative edible oil显示文摘 | Kim Wei Chan Maznah Ismail | 2008 | Food Chemistry2008，，3： | 1 |
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