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| 1 | High salt primes a specific activation state of macrophages, M(Na)显示文摘 | Wu-Chang Zhang Xiao-Jun Zheng Lin-Juan Du Jian-Yong Sun Zhu-Xia Shen Chaoji Shi Shuyang Sun Zhiyuan Zhang Xiao-qing Chen Mu Qin Xu Liu Jun Tao Lijun Jia Heng-yu Fan Bin Zhou Ying Yu Hao Ying Lijian Hui Xiaolong Liu Xianghua Yi Xiaojing Liu Lanjing Zhang Sheng-Zhong Duan | 2015 | Cell Research2015，25，8： | 15 |
| 2 | Defect-mediated reactivity of Pt/TiO2 catalysts:the different role of titanium and oxygen vacancies显示文摘Defects are ubiquitous in oxide supports and can often tune the catalytic property of supported metal catalysts.This work describes the distinct role of titanium and oxygen vacancies of TiO2 supports in the catalytic performance of supported Pt catalysts for CO oxidation.Pt was loaded on the TiO2 supports with oxygen vacancies(VO-TiO2)and titanium vacancies(VTiTiO2).It was found that different defects of TiO2 could distinctively modify the electron property of Pt and thereby CO adsorption strength.The strength of CO adsorption on Pt/VTi-TiO2 is enhanced,while that of Pt/VO-TiO2 becomes weaker.Additionally,the presence of defects would also promote the reducibility of catalysts.On the account of the superior redox ability,both Pt/VTi-TiO2 and Pt/VO-TiO2 exhibit a higher activity than Pt supported on normal TiO2 for CO oxidation. | Quan Xiao Yanan Wang Zhi-Jian Zhao Chunlei Pei Sai Chen Lijun Gao Rentao Mu Qiang Fu Jinlong Gong | 2020 | Science China Chemistry2020，63，9： | 4 |
| 3 | Therapies for children with cerebral palsy A Web of Science-based literature analysis显示文摘OBJECTIVE: To identify global research trends in three therapies for children with cerebral palsy. DATA RETRIEVAL: We performed a bibliometric analysis of studies on therapies for children with cerebral palsy from 2002 to 2011 retrieved from Web of Science. SELECTION CRITERIA: Inclusion criteria: (a) peer-reviewed published articles on botulinum toxin, constraint-induced movement therapy, or acupuncture for children with cerebral palsy indexed in Web of Science; (b) original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items; and (c) publication between 2002 and 2011. Exclusion criteria: (a) articles that required manual searching or telephone access; (b) documents that were not published in the public domain; and (c) a number of corrected papers from the total number of articles. MAIN OUTCOME MEASURES: (1) Number of publications on the three therapies; (2) annual publication output, distribution by journals, distribution by institution, and top-cited articles on botulinum toxin; (3) annual publication output, distribution by journal, distribution by institution, and top-cited articles on constraint-induced movement therapy; (4) annual publication, distribution by journal, distribution by institution, and top-cited articles on acupuncture. RESULTS: This analysis, based on Web of Science articles, identified several research trends in studies published over the past 10 years of three therapies for children with cerebral palsy. More articles on botulinum toxin for treating children with cerebral palsy were published than the articles regarding constraint-induced movement therapy or acupuncture. The numbers of publications increased over the 10-year study period. Most papers appeared in journals with a focus on neurology, such as Developmental Medicine and Child Neurology and Journal of Child Neurology.Research institutes publishing on botulinum toxin treatments for this population are mostly in the Netherlands, the United States of America, and Australia; those publishing on constraint-induced movement therapy are mostly in Australia and the United States of America; and those publishing on acupuncture are mostly in China, Sweden and the United States of America.CONCLUSION: Analysis of literature and research trends indicated that there was no one specific therapy to cure cerebral palsy. Further studies are still necessary. | Yaping Mu Na Li Lijun Guan Chunnan Wang Shuyun Shang Yan Wang | 2012 | Neural Regeneration Research2012，7，33： | 2 |
| 4 | Rapid growth of cutaneous metastases after surgical resection of thrombospondin-secreting small blue round cell tumor of childhood显示文摘 | Susan E. Crawford E. Martin Flores-Stadler Lijun Huang Xiao-Di Tan Mark Ranalli Van Mu Frank Gonzalez-Crussi | 1998 | Human Pathology1998，，： | 1 |
| 5 | Interleukin-27 suppresses experimental autoimmune encephalomyelitis during bone marrow stromal cell treatment显示文摘 | Jinghua Wang Guangyou Wang Bo Sun Hulun Li Lili Mu Qi Wang Guozhong Li Lijun Shi Lianhong Jin Nikolaos Kostulas | 2007 | Journal of Autoimmunity2007，，4： | 1 |
| 6 | Volatile com- ponents in three commercial douchies, a Chinese traditional salt-fermented soybean food 显示文摘 | Wang Lijun Mu Huiling Liu Haijie | 2010 | International Journal of Food Properties2010，，13： | 1 |
| 7 | Bone Marrow Stromal Cells Control the Growth of Hepatic Stellate Cells in?vitro显示文摘 | Lijun Shi Guozhong Li Jinghua Wang Bo Sun Liming Yang Guangyou Wang Dandan Wang Lili Mu Hui Chen Lianhong Jin Nikolaos Kostulas Hulun Li | 2008 | Digestive Diseases and Sciences2008，，11： | 1 |
| 8 | Volatile components in three commercial douchies,a Chinese traditional salt-fermented soybean food显示文摘 | WANG Lijun MU Huiling LIU Haijie | | 0，，： | 1 |
| 9 | Overexpression of CmSOS1 confers waterlogging tolerance in Chrysanthemum显示文摘Plants experiencing hypoxia(a shortage of oxygen)are unable to maintain aerobic respiration,which leads to an energy and carbohydrate deficit.The pervasive and rapid accumulation of ethylene is an early and reliable response to hypoxic stress(Sasidharan and Voesenek 2015),producing an uptick in the accumulation of reactive oxygen species(ROS).This in turn triggers apoptosis in root cortex cells,eventually leading to the formation of lysigenous aerenchyma,a tissue from which ethylene is readily lost(Loreti et al.2016).In plants exposed to prolonged waterlogging,group VII ethylene response factors operate to activate the suite of genes required to establish anaerobic metabolism(Gibbs et al.2011);some of these genes are also modulated by ROS(Narsai et al.2011;Sasidharan and Voesenek 2015).The transcriptional activation of genes encoding group VII ethylene response factors is regulated by the hypoxia response attenuator 1(HRA1)protein(Pucciariello and Perata 2017).A link between the oxygen sensing and ROS signaling has been established involving the hypoxia‐responsive universal stress protein 1(HRU1),which interacts with the respiratory burst oxidase homolog D(RBOHD)(Gonzali et al.2015).Salinity also tends to induce ROS production(You and Chan 2015). | Lijun Wang Jiaojiao Gao Zixin Zhang Weimiao Liu Peilei Cheng Wenting Mu Tong Su Sumei Chen Fadi Chen Jiafu Jiang | 2020 | Journal of Integrative Plant Biology2020，62，8： | 1 |
| 10 | Evaluation of multi-stage fracturing by hydrajet, swellable packer, and compression packer techniques in horizontal openhole wells 显示文摘 | Mu Lijun Ma Xu Zhang Yanming | 2012 | SPE 1533282012，，： | 1 |
| 11 | Volatile components in three commercial douchies,a Chinese traditional saltfermented soybean food显示文摘 | Wang Lijun Mu Huiling Bhesh Bhandari | 2010 | International Journal of Food Properties2010，，13： | 1 |
| 12 | VvBBX44 and VvMYBA1 form a regulatory feedback loop to balance anthocyanin biosynthesis in grape显示文摘Anthocyanins are essential for the quality of perennial horticultural crops,such as grapes.In grapes,ELONGATED HYPOCOTYL 5(HY5)and MYBA1 are two critical transcription factors that regulate anthocyanin biosynthesis.Our previous work has shown that Vitis vinifera B-box protein 44(VvBBX44)inhibits anthocyanin synthesis and represses VvHY5 expression in grape calli.However,the regulatory mechanism underlying this regulation was unclear.In this study,we found that loss of VvBBX44 function resulted in increased anthocyanin accumulation in grapevine callus.VvBBX44 directly represses VvMYBA1,which activates VvBBX44.VvMYBA1,but not VvBBX44,directly modulates the expression of grape UDP flavonoid 3-O-glucosyltransferase(VvUFGT).We demonstrated that VvBBX44 represses the transcriptional activation of VvUFGT and VvBBX44 induced by VvMYBA1.However,VvBBX44 and VvMYBA1 did not physically interact in yeast.The application of exogenous anthocyanin stimulated VvBBX44 expression in grapevine suspension cells and tobacco leaves.These findings suggest that VvBBX44 and VvMYBA1 form a transcriptional feedback loop to prevent overaccumulation of anthocyanin and reduce metabolic costs.Our work sheds light on the complex regulatory network that controls anthocyanin biosynthesis in grapevine. | Wenwen Liu Huayuan Mu Ling Yuan Yang Li Yuting Li Shenchang Li Chong Ren Wei Duan Peige Fan Zhanwu Dai Yongfeng Zhou Zhenchang Liang Shaohua Li Lijun Wang | 2023 | Horticulture Research2023，10，10： | 0 |
| 13 | The class B heat shock factor HSFB1 regulates heat tolerance in grapevine显示文摘Grape is a widely cultivated crop with high economic value.Most cultivars derived from mild or cooler climates may not withstand increasing heat stress.Therefore,dissecting the mechanisms of heat tolerance in grapes is of particular significance.Here,we performed comparative transcriptome analysis of Vitis davidii‘Tangwei’(heat tolerant)and Vitis vinifera‘Jingxiu’(heat sensitive)grapevines after exposure to 25°C,40°C,or 45°C for 2 h.More differentially expressed genes(DEGs)were detected in‘Tangwei’than in‘Jingxiu’in response to heat stress,and the number of DEGs increased with increasing treatment temperatures.We identified a class B Heat Shock Factor,HSFB1,which was significantly upregulated in‘Tangwei’,but not in‘Jingxiu’,at high temperature.VdHSFB1 from‘Tangwei’and VvHSFB1 from‘Jingxiu’differ in only one amino acid,and both showed similar transcriptional repression activities.Overexpression and RNA interference of HSFB1 in grape indicated that HSFB1 positively regulates the heat tolerance.Moreover,the heat tolerance of HSFB1-overexpressing plants was positively correlated to HSFB1 expression level.The activity of the VdHSFB1 promoter is higher than that of VvHSFB1 under both normal and high temperatures.Promoter analysis showed that more TATA-box and AT∼TATA-box cis-elements are present in the VdHSFB1 promoter than the VvHSFB1 promoter.The promoter sequence variations between VdHSFB1 and VvHSFB1 likely determine the HSFB1 expression levels that inf luence heat tolerance of the two grape germplasms with contrasting thermotolerance.Collectively,we validated the role of HSFB1 in heat tolerance,and the knowledge gained will advance our ability to breed heat-tolerant grape cultivars. | Haiyang Chen Xinna Liu Shenchang Li Ling Yuan Huayuan Mu Yi Wang Yang Li Wei Duan Peige Fan Zhenchang Liang Lijun Wang | 2023 | Horticulture Research2023，10，3： | 0 |
| 14 | Alloy-induced reduction and anisotropy change of lattice thermal conductivity in Ruddlesden–Popper phase halide perovskites显示文摘The effective modulation of the thermal conductivity of halide perovskites is of great importance in optimizing their optoelectronic device performance.Based on first-principles lattice dynamics calculations,we found that alloying at the B and X sites can significantly modulate the thermal transport properties of 2D Ruddlesden−Popper(RP)phase halide perovskites,achieving a range of lattice thermal conductivity values from the lowest(κ_(c)=0.05 W·m^(−1)·K^(−1)@Cs_(4)AgBiI_(8))to the highest(κ_(a/b)=0.95 W·m^(−1)·K^(−1)@Cs4NaBiCl_(4)I_(4)).Compared with the pure RP-phase halide perovskites and three-dimensional halide perovskite alloys,the two-dimensional halide perovskite introduces more phonon branches through alloying,resulting in stronger phonon branch coupling,which effectively scatters phonons and reduces thermal conductivity.Alloying can also dramatically regulate the thermal transport anisotropy of RP-phase halide perovskites,with the anisotropy ratio ranging from 1.22 to 4.13.Subsequently,analysis of the phonon transport modes in these structures revealed that the lower phonon velocity and shorter phonon lifetime were the main reasons for their low thermal conductivity.This work further reduces the lattice thermal conductivity of 2D pure RP-phase halide perovskites by alloying methods and provides a strong support for theoretical guidance by gaining insight into the interesting phonon transport phenomena in these compounds. | Huimin Mu Kun Zhou Fuyu Tian Yansong Zhou Guoqi Zhao Yuhao Fu Lijun Zhang | 2023 | Frontiers of physics2023，18，6： | 0 |
| 15 | A technique for enhancing tight oil recovery by multi-field reconstruction and combined displacement and imbibition显示文摘A seepage-geomechanical coupled embedded fracture flow model has been established for multi-field coupled simulation in tight oil reservoirs,revealing the patterns of change in pressure field,seepage field,and stress field after long-term water injection in tight oil reservoirs.Based on this,a technique for enhanced oil recovery(EOR)combining multi-field reconstruction and combination of displacement and imbibition in tight oil reservoirs has been proposed.The study shows that after long-term water flooding for tight oil development,the pressure diffusion range is limited,making it difficult to establish an effective displacement system.The variation in geostress exhibits diversity,with the change in horizontal minimum principal stress being greater than that in horizontal maximum principal stress,and the variation around the injection wells being more significant than that around the production wells.The deflection of geostress direction around injection wells is also large.The technology for EOR through multi-field reconstruction and combination of displacement and imbibition employs water injection wells converted to production and large-scale fracturing techniques to restructure the artificial fracture network system.Through a full lifecycle energy replenishment method of pre-fracturing energy supplementation,energy increase during fracturing,well soaking for energy storage,and combination of displacement and imbibition,it effectively addresses the issue of easy channeling of the injection medium and difficult energy replenishment after large-scale fracturing.By intensifying the imbibition effect through the coordination of multiple wells,it reconstructs the combined system of displacement and imbibition under a complex fracture network,transitioning from avoiding fractures to utilizing them,thereby improving microscopic sweep and oil displacement efficiencies.Field application in Block Yuan 284 of the Huaqing Oilfield in the Ordos Basin has demonstrated that this technology increases the recovery factor by 12 percentage points,enabling large scale and efficient development of tight oil. | LEI Zhengdong WANG Zhengmao MU Lijun PENG Huanhuan LI Xin BAI Xiaohu TAO Zhen LI Hongchang PENG Yingfeng | 2024 | Petroleum Exploration and Development2024，51，1： | 0 |
| 16 | Trilogy of drug repurposing for developing cancer and chemotherapy-induced heart failure co-therapy agent显示文摘Chemotherapy-induced complications,particularly lethal cardiovascular diseases,pose significant challenges for cancer survivors.The intertwined adverse effects,brought by cancer and its complication,further complicate anticancer therapy and lead to diminished clinical outcomes.Simple supplementation of cardioprotective agents falls short in addressing these challenges.Developing bifunctional co-therapy agents provided another potential solution to consolidate the chemotherapy and reduce cardiac events simultaneously.Drug repurposing was naturally endowed with co-therapeutic potential of two indications,implying a unique chance in the development of bi-functional agents.Herein,we further proposed a novel“trilogy of drug repurposing”strategy that comprises function-based,targetfocused,and scaffold-driven repurposing approaches,aiming to systematically elucidate the advantages of repurposed drugs in rationally developing bi-functional agent.Through function-based repurposing,a cardioprotective agent,carvedilol(CAR),was identified as a potential neddylation inhibitor to suppress lung cancer growth.Employing target-focused SAR studies and scaffold-driven drug design,we synthesized 44 CAR derivatives to achieve a balance between anticancer and cardioprotection.Remarkably,optimal derivative 43 displayed promising bi-functional effects,especially in various self-established heart failure mice models with and without tumor-bearing.Collectively,the present study validated the practicability of the“trilogy of drug repurposing”strategy in the development of bi-functional cotherapy agents. | Xin Chen Xianggang Mu Lele Ding Xi Wang Fei Mao Jinlian Wei Qian Liu Yixiang Xu Shuaishuai Ni Lijun Jia Jian Li | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
| 17 | A New Neutron-deficient Isotope ^(235)Am显示文摘A New Neutron-deficient Isotope ^(235)AmANewNeutron-deficientIsotope^(235)Am￥LiuHongye;GuoJunsheng;GanZaiguo;YangWeifan;ShiLij... | Liu Hongye Guo Junsheng Gan Zaiguo Yang Weifan Shi Lijun Mu Wantong Guo Tianrui Fang Keging Shen Shuifa Yuan Shuanggui Zhang Xueqian Qin Zi Ma Ruichang Zhong Jiquan Wang Shunhong Kong Dengging and Qiao Jimin | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 18 | Anisotropic phonon thermal transport in two-dimensional layered materials显示文摘Two-dimensional layered materials(2DLMs)have attracted growing attention in optoelectronic devices due to their intriguing anisotropic physical properties.Different members of 2DLMs exhibit unique anisotropic electrical,optical,and thermal properties,fundamentally related to their crystal structure.Among them,directional heat transfer plays a vital role in the thermal management of electronic devices.Here,we use density functional theory calculations to investigate the thermal transport properties of representative layered materials:β-InSe,γ-InSe,MoS2,and h-BN.We found that the lattice thermal conductivities ofβ-InSe,γ-InSe,MoS_(2),and h-BN display diverse anisotropic behaviors with anisotropy ratios of 10.4,9.4,64.9,and 107.7,respectively.The analysis of the phonon modes further indicates that the phonon group velocity is responsible for the anisotropy of thermal transport.Furthermore,the low lattice thermal conductivity of the layered InSe mainly comes from low phonon group velocity and atomic masses.Our findings provide a fundamental physical understanding of the anisotropic thermal transport in layered materials.We hope this study could inspire the advancement of 2DLMs thermal management applications in next-generation integrated electronic and optoelectronic devices. | Yuxin Cai Muhammad Faizan Huimin Mu Yilin Zhang Hongshuai Zou Hong Jian Zhao Yuhao Fu Lijun Zhang | 2023 | Frontiers of physics2023，18，4： | 0 |
| 19 | Pregnancy and Childbirth After Sertoli-Leydig Cell Tumor Resection:A Case Study and Literature Review显示文摘Objectives:To explore the clinical manifestations and pathological features in the biopsy of ovarian Sertoli-Leydig cell tumor,as well as to improve the clinical understanding of the disease.Methods:A case of pregnancy and childbirth after Sertoli-Leydig cell tumor resection was retrospectively analyzed.The patients’clinical data were collected,including the clinical manifestations,postoperative biopsy results,auxiliary examination results,immunohistochemical results,treatment,and prognosis of the patient.Results:(1)SLCT occurred unilaterally;(2)according to the International Federation of Obstetrics and Gynecology(FIGO),the clinical staging was stage IA;according to the pathological classification of malignant tumors,it was gradeⅡ(moderately differentiated);(3)a healthy female live baby was delivered.Conclusion:Such tumors are rare low-grade malignancies and are even rarer in pregnancy.An increase in preoperative testosterone levels with positive ultrasonography results can be used to assist diagnosis;however,postoperative biopsy pathology remains the“gold standard”for the diagnosis of SLCTs.The definite diagnosis of SLCTs is of great significance for surgical planning and prognostic evaluation. | Lijun Mu Lihong Zhu | 2022 | Proceedings of Anticancer Research2022，6，4： | 0 |
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