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| 1 | Transcatheter aortic valve implantation:Current status and future perspectives显示文摘Although surgical aortic valve replacement is the standard therapy for severe aortic stenosis(AS),about one third of patients are considered inoperable due to unacceptable surgical risk.Under medical treatment alone these patients have a very poor prognosis with a mortality rate of 50%at 2 years.Transcatheter aortic valve implantation(TAVI)has been used in these patients,and has shown robust results in the only randomized clinical trial of severe AS treatment performed so far.In this review,we will focus on the two commercially available systems:Edwards SAPIEN valve and CoreValve Revalving system.Both systems have demonstrated success rates of over 90%with 30-d mortality rates below 10%in the most recent transfemoral TAVI studies.Moreover,long-term studies have shown that the valves have good haemodynamic performance.Some studies are currently exploring the non-inferiority of TAVI procedures vs conventional surgery in high-risk patients,and long-term clinical results of the percutaneous valves.In this article we review the current status of TAVI including selection of patients,a comparison of available prostheses,results and complications of the procedure,clinical outcomes,and future perspectives. | Pablo Salinas Raul Moreno Jose L Lopez-Sendon | 2011 | World Journal of Cardiology2011，3，6： | 5 |
| 2 | Pseudoclitocybaceae fam. nov. (Agaricales, Tricholomatineae), a new arrangement at family, genus and species level显示文摘A new classification of several clitocyboid taxa is here proposed to accommodate results from multigenic phylogenetic inference.The analysis of ITS rDNA as well as a combined dataset including 18S and 28S rDNA,tef1 and rpb2 data,support significantly a shared monophyletic origin of the genera Pseudoclitocybe,Musumecia and Pogonoloma,and the species Clitocybe alexandri and C.harperi.The new family Pseudoclitocybaceae is here proposed to name this clade,characterized by the presence of loop-like clamp connections in most species,absence of cystidia,and parallel hymenophoral trama with broad,cylindrical hyphae with intracellular granulations.The new genera Clitopaxillus and Harmajaea are proposed to accommodate the type species C.alexandri and H.harperi,as well as the combination H.wellsiae.In addition,two new species are described:C.fibulatus has a differential distribution of clamp connections in the basidiome,while H.guldeniae is,by now,an exclusively European taxon with brownish pileus,somewhat decurrent gills,ovoid spores and basidia longer than those of H.harperi.Finally,the species concept within Pseudoclitocybe and Pogonoloma is discussed and descriptions of the most representative species are provided. | Pablo Alvarado Pierre-Arthur Moreau Balint Dima Alfredo Vizzini Giovanni Consiglio Gabriel Moreno Ledo Setti Tapio Kekki Seppo Huhtinen Kare Liimatainen Tuula Niskanen | 2018 | Fungal Diversity2018，，3： | 2 |
| 3 | E6 molecular variants of human papillomavirus (HPV) type 16: An updated and unified criterion for clustering and nomenclature显示文摘 | Antonio Huertas-Salgado Diana C. Martín-Gámez Pablo Moreno Raúl Murillo María Mercedes Bravo Luisa Villa Mónica Molano | 2010 | Virology2010，，： | 2 |
| 4 | 在经历 transcatheter 的病人的 atrial 纤维性颤动的临床、预示的含意大动脉的阀门培植显示文摘 AIM: To study a cohort of consecutive patients under-going transcatheter aortic valve implantation (TAVI) and compare the outcomes of atrial fibrillation (AF) patients vs patients in sinus rhythm (SR). METHODS: All consecutive patients undergoing TAVI in our hospital were included. The AF group comprised patients in AF at the time of TAVI or with history of AF, and were compared with the SR group. Procedural, echocardiographic and follow-up variables were compared. Likewise, the CHA 2 DS 2-VASC stroke risk score and HAS-BLED bleeding risk score and antithrombotic treatment at discharge in AF patients were compared with that in SR patients. RESULTS: From a total of 34 patients undergoing TAVI, 17 (50%) were allocated to the AF group, of whom 15 (88%) were under chronic oral anticoagulation. Patients in the AF group were similar to those in the SR group except for a trend (P = 0.07) for a higher logistic EuroSCORE (28% vs 19%), and a higher prevalence of hypertension (82% vs 53%) and chronic renal failure (17% vs 0%). Risk of both stroke and bleeding was high in the AF group (mean CHA 2 DS 2-VASC 4.3, mean HAS-BLED 2.9). In the AF group, treatment at discharge included chronic oral anticoagulation in all except one case, and in association with an antiplatelet drug in 57% of patients. During a mean follow-up of 11 mo (maximum 32), there were only two strokes, none of them during the peri-procedural period: one in the AF group at 30 mo and one in the SR group at 3 mo. There were no statistical differences in procedural success, and clinical outcome (survival at 1 year 81% vs 74% in AF and SR groups, respectively, P = NS). CONCLUSION: Patients in AF undergoing TAVI show a trend to a higher surgical risk. However, in our cohort, patients in AF did not have a higher stroke rate compared to the SR group, and the prognosis was similar in both groups. | Pablo Salinas Raúl Moreno Luis Calvo Santiago Jiménez-Valero Guillermo Galeote Angel Sánchez-Recalde Teresa López-Fernández Sergio Garcia-Blas Diego Iglesias Luis Riera Isidro Moreno-Gómez Jose María Mesa Ignacio Plaza Rocio Ayala Rosa Gonzalez José-Luis López-Sendón | 2012 | World Journal of Cardiology2012，4，1： | 2 |
| 5 | Regulatory and Functional Connection of Microphthalmia-Associated Transcription Factor and Anti-Metastatic Pigment Epithelium Derived Factor in Melanoma显示文摘 | Asunción Fernández-Barral Jose Luis Orgaz Pablo Baquero Zaheer Ali Alberto Moreno María Tiana Valentí Gómez Erica Riveiro-Falkenbach Carmen Ca?adas Sandra Zazo Corine Bertolotto Irwin Davidson Jose Luis Rodríguez-Peralto Ignacio Palmero Federico Rojo Lass | 2014 | Neoplasia2014，，： | 1 |
| 6 | A new experimental model of glaucoma in rats through intracameral injections of hyaluronic acid显示文摘 | María Cecilia Moreno Hernán J. Aldana Marcos J. Oscar Croxatto Pablo H. Sande Julieta Campanelli Carolina O. Jaliffa Jorge Benozzi Ruth E. Rosenstein | 2005 | Experimental Eye Research2005，，1： | 1 |
| 7 | Retinal Oxidative Stress Induced by High Intraocular Pressure显示文摘 | María Cecilia Moreno Julieta Campanelli Pablo Sande Daniel A. Sáenz María Inés Keller Sarmiento Ruth E. Rosenstein | 2004 | Free Radical Biology and Medicine2004，，6： | 1 |
| 8 | Cardiovas-cular morbimortality reduction after an acute cardiovascularevent through multifactorial and intensive cardiovascularrisk factors management(MIRVAS project)显示文摘 | Moreno Palanco M A Ciria de Pablo C | 2007 | MedClin(Barc)2007，129，7： | 1 |
| 9 | Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain显示文摘 | Lana J. Mawhinney Juan Pablo de Rivero Vaccari Ofelia F. Alonso Christopher A. Jimenez Concepción Furones W. Javier Moreno Michael C. Lewis W. Dalton Dietrich Helen M. Bramlett | 2011 | Brain Research2011，，： | 1 |
| 10 | Coffee attenuates fibrosis by decreasing the expression of TGF‐β and CTGF in a murine model of liver damage显示文摘 | Jonathan Arauz Marina Galicia‐ Moreno Pedro Cortés‐Reynosa Eduardo Pérez Salazar Pablo Muriel | 2013 | J Appl Toxicol2013，，9： | 1 |
| 11 | Gluten immunogenic peptide excretion detects dietary transgressions in treated celiac disease patients显示文摘BACKGROUND Life-long removal of gluten from the diet is currently the only way to manage celiac disease(CeD). Until now, no objective test has proven useful to objectively detect ingested gluten in clinical practice. Recently, tests that determine consumption of gluten by assessing excretion of gluten immunogenic peptides(GIP) in stool and urine have been developed. Their utility, in comparison with conventional dietary and analytical follow-up strategies, has not been fully established.AIM To assess the performance of enzyme-linked immunosorbent assay(ELISA) and point-of-care tests(PoCTs) for GIP excretion in CeD patients on gluten-free diet(GFD).METHODS We conducted an observational, prospective, cross-sectional study in patients following a GFD for at least two years. Using the Gastrointestinal Symptom Rating Scale questionnaire, patients were classified at enrollment as asymptomatic or symptomatic. Gluten consumption was assessed twice by 3-d dietary recall and GIP excretion(by ELISA in stool and PoCTs(commercial kits for stool and urine) in two consecutive samples. These samples and dietary reports were obtained 10 day apart one from the other. Patients were encouraged to follow their usual GFD during the study period.RESULTS Forty-four patients were enrolled, of which 19(43.2%) were symptomatic despite being on a GFD. Overall, 83 sets of stool and/or urine samples were collected.Eleven out of 44 patients(25.0%) had at least one positive GIP test. The occurrence of at least one positive test was 32% in asymptomatic patients compared with 15.8% in symptomatic patients. GIP was concordant with dietary reports in 65.9% of cases(Cohen′s kappa: 0.317). PoCT detected dietary indiscretions. Both ELISA and PoCT in stool were concordant(concomitantly positive or negative) in 67 out of 74(90.5%) samples. Excretion of GIP was detected in 7(8.4%) stool and/or urine samples from patients considered to be strictly compliant with the GFD by dietary reports.CONCLUSION GIP detects dietary transgressions in patients on long-term GFD, irrespective of the presence of symptoms. PoCT for GIP detection constitutes a simple homebased method for self-assessment of dietary indiscretions. | Ana Florencia Costa Emilia Sugai María de la Paz Temprano Sonia Isabel Niveloni Horacio Vázquez María Laura Moreno M.Remedios Domínguez-Flores Alba Mu?oz-Suano Edgardo Smecuol Juan Pablo Stefanolo Andrea F González Angel Cebolla-Ramirez Eduardo Mauri?o Elena F Verdú Julio César Bai | 2019 | World Journal of Gastroenterology2019，25，11： | 1 |
| 12 | Coffee attenuates fibrosis by decreasing the expression of TGF‐β and CTGF in a murine model of liver damage显示文摘 | Jonathan Arauz Marina Galicia‐ Moreno Pedro Cortés‐Reynosa Eduardo Pérez Salazar Pablo Muriel | 2013 | J Appl Toxicol2013，，9： | 1 |
| 13 | The IMS service platform:a sulution for next-generation network operators to be more than bit pipes显示文摘 | Cuevas Antonio Moreno José Ignacio Vidales Pablo | | 0，，08： | 1 |
| 14 | Noncirrhotic portal hypertension in HIV-infected patients: unique clinical and pathological findings显示文摘 | Eugenia Vispo Alberto Moreno Ivana Maida Pablo Barreiro Adrián Cuevas Sonia Albertos Vincent Soriano | 2010 | AIDS2010，，8： | 1 |
| 15 | Comparison of ex vivo expansion culture conditions of mesenchymal stem cells for human cell therapy显示文摘 | Maitane Pérez‐Ilzarbe María Díez‐Campelo Pablo Aranda Soraya Tabera Tania Lopez Consuelo del Ca?izo Juana Merino Cristina Moreno Enrique J. Andreu Felipe Prósper José Antonio Pérez‐Simón | 2009 | Transfusion2009，，9： | 1 |
| 16 | Candidate genes and QTLs for fruit ripening and softening in melon显示文摘 | Eduard Moreno Javier M. Obando Noelia Dos-Santos J. Pablo Fernández-Trujillo Antonio J. Monforte Jordi Garcia-Mas | 2008 | Theoretical and Applied Genetics2008，，4： | 1 |
| 17 | Crystal Structure of Ovocleidin-17, a Major Protein of the Calcified Gallus gallus Eggshell显示文摘 | Juan Pablo Reyes-Grajeda Abel Moreno Antonio Romero | 2004 | Journal of Biological Chemistry2004，279，40： | 1 |
| 18 | Electromgnetic transients in underground transmission systems through the numerical Laplace tmnsform 显示文摘 | Felipe Alejandro Uribe Jose Luis Naredo Pablo Moreno | 2002 | Electrical Power and Energy systems2002，，24： | 1 |
| 19 | Hepatic Expression of Candidate Genes in Patients With Alcoholic Hepatitis: Correlation With Disease Severity显示文摘 | Jordi Colmenero Ramón Bataller Pau Sancho–Bru Pablo Bellot Rosa Miquel Montserrat Moreno Pedro Jares Jaime Bosch Vicente Arroyo Joan Caballería Pere Ginès | 2007 | Gastroenterology2007，，2： | 1 |
| 20 | Development of 99m Tc(CO) 3 -dendrimer-FITC for cancer imaging显示文摘 | Marcos R. Tassano Paola F. Audicio Juan P. Gambini Marcelo Fernandez Juan P. Damian Maria Moreno Jose A. Chabalgoity Omar Alonso Juan C. Benech Pablo Cabral | 2011 | Bioorganic & Medicinal Chemistry Letters2011，，18： | 1 |
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