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17篇 您的检索式:作者名="PengHong"
    题名 作者 年代 出处 被引量
1ANALYTICAL SOLUTIONS TO EXPANSION OF CYLINDRICAL CAVITY IN LINEAR SOFTENING SOIL显示文摘Based on the results of conventional triaxial compression tests for a soil, a trilinear elasto-plastic model is proposed to simulate the stress-strain softening curve. According to this curve, the constitutive relation between the bulk strain and two principal strains is established. By using Mohr-Coulomb’s yield criterion as the initial yield function with plastic ?ow phases stage and constructing the rational yield function for the strain softening phase stage, the analytical solutions to the stress, strain, and displacement ?elds for the expansion of cylindrical cavity are presented. Finally, a computational example is used to show the radii of di?erent stress zones and the corresponding internal pressure.ZhengJunjie PengHong NieChongjun 2004Acta Mechanica Solida Sinica2004,17,4:8
2Exact periodic and blow up solutions for 2D Ginzburg–Landau equation显示文摘Penghong Zhong Ronghui Yang Ganshan Yang 2008Physics Letters A2008,,1:1
3显示文摘PENGHong—Xia(彭红霞) LIUGui—Xia(刘桂霞) DONGXiang—rring(董相廷) etat 2012无机化学学报2012,287,:1
4Exact periodic and blow up solutions for 2D Ginzburg-Landau equation显示文摘Zhong Penghong Yang Ronghui Yang Ganshan 2008Physics Letters A2008,373,1:1
5The in- fluence of air content in water on ultrasonic cavitation field 显示文摘LIU Liyan YANG Yang LIU Penghong 2014Uhrason Sonochem2014,21,2:1
6Potential oscillations across oil-water interface in the presence of the biological surfactant and amino acids or polypeptides显示文摘A lot of potential oscillations across oil_water interface ahve been designed by using various surfactants and biological surfactants in the aqueous phase and various amino acids or even polypeptides in the oil phase (nitrobenzene solution). Effects of the reactant’s concentration and the reaction temperature on the oscillating parameters have been studied. The oscillating mechanism has been discussed, and a model fo the oscillating mechanism has been proposed which is proved qualitatively reasonable according to the simulation.Li Hexing Li Penghong Lu Jing 1998Chinese Science Bulletin1998,43,12:1
7Exact periodic and blow up solutions for 2D Ginzburg-Landau equation显示文摘Zhong Penghong Yang Ronghui Yang Ganshan 0,,01:1
8Exact periodic and blow up solutions for 2D Ginzburg-Landau equation 显示文摘ZHONG Penghong YANG Ronghui YANG Ganshan 2008Physics Letters A2008,373,:1
9Effect of Temperature on Thermal Treatment of Silica Coated Magnetic Nanoparticles显示文摘LI Yu ZHANG Penghong ZHAO Huipeng DU Xiaoqiang LI Junping LIU Laishuan 2018Chemical Research in Chinese Universities2018,34,5:0
10U.S.Sanctions against Iran and Their Impact on China显示文摘The energy and financial sanctions imposed by the U.S.against Iran encompass other countries' financial institutions.This paper argues that though it is impossible to suddenly stop oil imports from Iran,China can gradually reduce its dependence on Iranian crude oil and try to ensure the legitimate business of its financial institutions in U.S.market.Cai Penghong 2012Contemporary International Relations2012,22,3:0
11Application of biocompatible custom ceria nanoparticles in improving the quality of liver grafts for transplantation显示文摘Liver transplantation(LT),an ultimate and vital method for treating end-stage liver disease,is often accompanied by ischemiareperfusion injury(IRI)resulting from warm or cold ischemia of the donor liver.Organ protection techniques are used to improve the quality of liver grafts(from retrieval to implantation).Reactive oxygen species(ROS)cause oxidative stress,which is considered a crucial factor in IRI after LT.Nano antioxidants capable of scavenging ROS alleviate IRI in multiple types of organs and tissues.In this study,we synthesized ceria nanoparticles(NPs)with antioxidant properties using a pyrolysis method and covered them with phospholipid-polyethylene glycol to improve their biocompatibility in vivo.We investigated the potential organprotective effect of ceria NPs and the underlying mechanisms.Ceria NPs promoted liver function recovery after LT by attenuating IRI in liver grafts in vivo.The protective effect of ceria NPs on liver grafts was investigated by applying hypothermic oxygenated machine perfusion ex vivo.Ceria NPs attenuated hypoxia reoxygenation-or H_(2)O_(2)-induced hepatocyte injury by enhancing mitochondrial activity and ROS scavenging in vitro.These effects may be associated with the activation of the nuclear factor erythroid-derived 2-related factor 2(Nrf2)/Kelch-like ECH-associated protein 1(Keap1)/heme oxygenase 1(HO-1)signaling pathway.In conclusion,ceria NPs may serve as a promising antioxidant agent for the treatment of hepatic IRI after LT.Yinbiao Qiao Jianhui Li Suchen Bian Chenyue Zhan Jia Luo Li Jiang Haoyu Li Hao Wu Cheng Zhang Shusen Zheng Haiyang Xie Penghong Song 2023Nano Research2023,16,4:0
12Culture of patient-derived multicellular clusters in suspended hydrogel capsules for pre-clinical personalized drug screening显示文摘A personalized medication regimen provides precise treatment for an individual and can be guided by pre-clinical drug screening.The economical and high-efficiency simulation of the liver tumor microenvironment(TME)in a drug-screening model has high value yet challenging to accomplish.Herein,we propose a simulation of the liver TME with suspended alginate-gelatin hydrogel capsules encapsulating patient-derived liver tumor multicellular clusters,and the culture of patient-derived tumor organoids(PDTOs)for personalized pre-clinical drug screening.The hydrogel capsule offers a 3D matrix environment with mechanical and biological properties similar to those of the liver in vivo.As a result,18 of the 28 patient-derived multicellular clusters were successfully cultured as PDTOs.These PDTOs,along with hepatocyte growth factor(HGF)of non-cellular components,preserve stromal cells,including cancer-associated fibroblasts(CAFs)and vascular endothelial cells(VECs).They also maintain stable expression of molecular markers and tumor heterogeneity similar to those of the original liver tumors.Drugs,including cabazitaxel,oxaliplatin,and sorafenib,were tested in PDTOs.The sensitivity of PDTOs to these drugs differs between individuals.The sensitivity of one PDTO to oxaliplatin was validated using magnetic resonance imaging(MRI)and biochemical tests after oxaliplatin clinical treatment of the corresponding patient.Therefore,this approach is promising for economical,accurate,and high-throughput drug screening for personalized treatment.Haijiang Dong Zequn Li Suchen Bian Guangyuan Song Wenfeng Song Mingqi Zhang Haiyang Xie Shusen Zheng Xuxu Yang Tiefeng Li Penghong Song 2022Bioactive Materials2022,7,12:0
13Silk road dance exhibition system based on motion capture显示文摘Silk Road dance is an excellent traditional Chinese dance drama, which has high artistic values. This article introduces the virtual performance techniques of Silk Road based on motion capture. First, obtain the dance data using motion capture technique according to the features of dance itself, then establish figure model, finally combines these data to make 3-D animation system to perform Silk Road, meanwhile designs some interfaces to introduce it. This system excavates details of the dance, and can be reference of man-machine interaction and animation production.Lu Ming PengHong Jia Gengyun 2016Computer Aided Drafting,Design and Manufacturing2016,26,4:0
14SERPINE2 promotes liver cancer metastasis by inhibiting c-Cbl-mediated EGFR ubiquitination and degradation显示文摘Background:Liver cancer is a malignancy with high morbidity and mortality rates.Serpin family E member 2(SERPINE2)has been reported to play a key role in the metastasis of many tumors.In this study,we aimed to investigate the potential mechanism of SERPINE2 in liver cancer metastasis.Methods:The Cancer Genome Atlas database(TCGA),including DNA methy-lation and transcriptome sequencing data,was utilized to identify the crucial oncogene associated with DNA methylation and cancer progression in liver can-cer.Data from the TCGA and RNA sequencing for 94 pairs of liver cancer tissues were used to explore the correlation between SERPINE2 expression and clin-ical parameters of patients.DNA methylation sequencing was used to detect the DNA methylation levels in liver cancer tissues and cells.RNA sequencing,cytokine assays,immunoprecipitation(IP)and mass spectrometry(MS)assays,protein stability assays,and ubiquitination assays were performed to explore the regulatory mechanism of SERPINE2 in liver cancer metastasis.Patient-derived xenografts and tumor organoid models were established to determine the role of SERPINE2 in the treatment of liver cancer using sorafenib.Results:Based on the public database screening,SERPINE2 was identified as a tumor promoter regulated by DNA methylation.SERPINE2 expression was significantly higher in liver cancer tissues and was associated with the dismal prognosis in patients with liver cancer.SERPINE2 promoted liver cancer metas-tasis by enhancing cell pseudopodia formation,cell adhesion,cancer-associated fibroblast activation,extracellular matrix remodeling,and angiogenesis.IP/MS assays confirmed that SERPINE2 activated epidermal growth factor receptor(EGFR)and its downstream signaling pathways by interacting with EGFR.Mechanistically,SERPINE2 inhibited EGFR ubiquitination and maintained its protein stability by competing with the E3 ubiquitin ligase,c-Cbl.Additionally,EGFR was activated in liver cancer cells after sorafenib treatment,and SER-PINE2 knockdown-induced EGFR downregulation significantly enhanced the therapeutic efficacy of sorafenib against liver cancer.Furthermore,we found that SERPINE2 knockdown also had a sensitizing effect on lenvatinib treatment.Conclusions:SERPINE2 promoted liver cancer metastasis by preventing EGFR degradation via c-Cbl-mediated ubiquitination,suggesting that inhibition of the SERPINE2-EGFR axis may be a potential target for liver cancer treatment.Shiyu Zhang Xing Jia Haojiang Dai Xingxin Zhu Wenfeng Song Suchen Bian Hao Wu Shinuo Chen Yangbo Tang Junran Chen Cheng Jin Mengqiao Zhou Haiyang Xie Shusen Zheng Penghong Song 2024Cancer Communications2024,44,3:0
15China-ASEAN Maritime Cooperation: Process, Motivation, and Prospects显示文摘Cai Penghong 2015China International Studies2015,35,4:0
16Trend in International Cooperation of China's Auto IndustryXie Penghong, AIB of MMI 1997中国汽车(英文版)1997,,4:0
17Thoughts on Integrated Monitoring of Ecological Environment at Provincial Level显示文摘The Law of Soil and Water Conservation entitles the administrations of water resources at various level to monitor ecological environment and to proclaim status of soil erosion periodically.Monitoring units of soil and water conservation approved by local governments are obliged to undertake this work.How to develop a monitoring program needs an overall and long-term concept.Particularity and objectives of ecological environment monitoring was discussed. Monitoring at provincial level may be divided into two levels:province-wide and at project level. Those indicators meaningful,sensitive to any disturbances,and simple to measure may be selected to test status of ecosystem stability and health.It makes sense to have an integrated sampling design,to set up permanent observation plots and to collect data, so that to have a relative timely,accurate understanding of ecosystems in the province.A program regarding sampling design,field methods, data analysis,documentation and implementation was detailed.PENGHong JackE.Coster SONGXiao-qiang 2004水土保持研究2004,11,2:0
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