|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A double-halocline structure in the Canada Basin of the Arctic Ocean显示文摘A year-round halocline is a particular hydrographic structure in the upper Arctic Ocean. On the basis of an analysis of the hydrographic data collected in the Arctic Ocean, it is found that a double-halocline structure exists in the upper layer of the southern Canada Basin, which is absolutely different from the Cold Halocline Layer (CHL) in the Eurasian Basin. The Pacific-origin water is the primary factor in the formation of the double-halocline structure. The upper halocline lies between the summer modification and the winter modification of the Pacific-origin water while the lower halocline results from the Pacific-origin water overlying upon the Atlantic-origin water. Both haloclines are all the year-round although seasonal and interannual variations have been detected in the historical data. | SHI Jiuxin ZHAO Jinping LI Shujiang CAO Yong QU Ping | 2005 | Acta Oceanologica Sinica2005，24，6： | 5 |
| 2 | A case of lethal hemolytic anemia associated with severe pneumonia caused by Mycoplasma pneumoniae显示文摘To the editor:A 31-year-old previous healthy male patient was admitted to the hospital with fever (Tmax 41℃) and non-productive cough for seven days and dyspnea for three days.On day 4 after disease onset,his chest X-ray showed right upper lung small opacity and left lung large opacity (Figure 1A).The patient has been administrated levofloxacin for two days before he came into our hospital. | Gu Li Chen Xiukai Li Huiqiao Qu Jiuxin Miao Miao Zhou Fei Zhu Yanyan Wang Xu Wang Chunlei Liu Yingmei Li Wenxiong Cao Bin | 2014 | Chinese Medical Journal2014，，21： | 3 |
| 3 | Immunological and metabolic characteristics of the Omicron variants infection显示文摘The Omicron variants of SARS-CoV-2,primarily authenticated in November 2021 in South Africa,has initiated the 5th wave of global pandemics.Here,we systemically examined immunological and metabolic characteristics of Omicron variants infection.We found Omicron resisted to neutralizing antibody targeting receptor binding domain(RBD)of wildtype SARS-CoV-2.Omicron could hardly be neutralized by sera of Corona Virus Disease 2019(COVID-19)convalescents infected with the Delta variant.Through mass spectrometry on MHC-bound peptidomes,we found that the spike protein of the Omicron variants could generate additional CD8+T cell epitopes,compared with Delta.These epitopes could induce robust CD8+T cell responses.Moreover,we found booster vaccination increased the cross-memory CD8+T cell responses against Omicron.Metabolic regulome analysis of Omicron-specific T cell showed a metabolic profile that promoted the response of memory T cells.Consistently,a greater fraction of memory CD8+T cells existed in Omicron stimulated peripheral blood mononuclear cells(PBMCs).In addition,CD147 was also a receptor for the Omicron variants,and CD147 antibody inhibited infection of Omicron.CD147-mediated Omicron infection in a human CD147 transgenic mouse model induced exudative alveolar pneumonia.Taken together,our data suggested that vaccination booster and receptor blocking antibody are two effective strategies against Omicron. | Jiejie Geng Xu Yang Kun Wang Ke Wang Ruo Chen Zhi-Nan Chen Chuan Qin Guizhen Wu Youchun Wang Ke Xu Peng Du Jiangning Liu Shirui Chen Tao Zhang Xiuxuan Sun Ting Guo Ying Shi Zheng Zhang Ding Wei Peng Lin Qingyi Wang Jing Yuan Jiuxin Qu Jin Zou Yingxia Liu Hongzhou Lu Ping Zhu Huijie Bian Liang Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 0 |
| 4 | Ventricular tachycardia in a disseminated MDR-TB patient: a case report and brief review of literature显示文摘尽管重要突破在肺结核管理被完成了,我们仍然在疾病的诊断和治疗遇到众多的困难。另外,新挑战,有不确定的临床的表示的 multidrug 抵抗的肺结核(MDR-TB ) ,经常导致推迟的诊断。在这份报纸,我们与室的纤维性颤动的稀罕表示报导了传播肺结核的一个案例,它对异菸肼和 rifampicin 证明抵抗。文学的评论与心包炎在肺结核病人显示出那室的纤维性颤动或心悸亢进或心肌炎偶发地在过去被报导了,但是任何一个都没被进行与 MDR-TB 感染包含病人。 | Hui Li Ran Li Jiuxin Qu Xiaomin Yu Zhixin Cao Yingmei Liu Bin Cao | 2014 | Frontiers of Medicine2014，8，2： | 0 |
| 5 | Interim proposal for collecting and handling of microbiology specimens from patients with COVID‐19 in general hospitals显示文摘1|INTRODUCTION Accurate pathogenic testing is essential for early diag-nosis and precise treatment of COVID‐19,and correct specimen collection and handling is vital for accurate diagnosis[1].With the continuing mutations,the pathogenicity of Severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)has gradually decreased,so the management of COVID‐19 in China has been down-graded to Class B(http://www.nhc.gov.cn).Infections with different SARS‐CoV‐2 variants produce variable clinical manifestations,and the types of specimens vary accordingly[2].The purpose of developing this guideline was to standardize the process of specimen collection and handling for microbiological testing from patients with confirmed or suspected COVID‐19 to avoid incorrect diagnosis and treatment. | Zhaofang Jiang Shan Chen Jiayao Qu Siyuan Liu Tao Hong Houming Liu Yi‐Wei Tang Jiuxin Qu Hongzhou Lu | 2023 | iLABMED2023，1，1： | 0 |
| 6 | Clinical application of intelligent technologies and integration in medical laboratories显示文摘With the development of scientific technology,the transition to the intelligent era of digitalization and automation is an irresistible trend for medical laboratories.Medical diagnosis systems have undergone significant changes as a result of intelligent technologies,such as machine learning,artificial intelligence,and the Internet of Things,from the collection,transmission,and detection of test samples to the review of reports and the provision of clinical feedback.In addition to significantly enhancing the efficiency,consistency,and accuracy of medical laboratory testing,these technologies also assist the improvement of individualized healthcare and medical expert systems,as well as the early detection and treatment of diseases.The future development of medical laboratories will focus on integrating big data and diverse intelligent resources,cooperating more closely with clinical departments,and realizing the effective pathway of patient‐centered care.The purpose of this review is to illustrate the current state of intelligent technology integration in medical laboratories and provide a preliminary discussion about the potential future influences of intelligent technology development on the evolution of medical laboratories. | Wenjie Huang Dongquan Huang Yeran Ding Cheng Yu Lei Wang Ning Lv Jiuxin Qu Hongzhou Lu | 2023 | iLABMED2023，1，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员