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| 1 | Venetoclax and low-dose cytarabine induced complete remissionin a patient with high-risk acute myeloid leukemia: a case report显示文摘Conventional combination therapies have not resulted in considerable progress in the treatment ofacute myeloid leukemia (AML). Elderly patients with AML and poor risk factors have grave prognosis.Midostaurin has been recently approved for the treatment of FLT-3-mutated AML. Venetoclax, a BCL-2 inhibitor,has been approved for the treatment of relapsed and/or refractory chronic lymphoid leukemia. Clinical trials onapplying venetoclax in combination with cytarabine and other agents to treat various hematological malignanciesare currently underway. Here, we present a case of a male patient with poor performance status and whodeveloped AML following allogeneic hematopoietic stem cell transplant for high-risk myelodysplasia. The patientwith high risk AML achieved complete response to the combined treatment regimen of low-dose cytarabine andvenetoclax. Furthermore, we reviewed current clinical trials on the use of venetoclax for hematologicalmalignancies. | Bingshan Liu Roshni Narurkar Madhura Hanmantgad Wahib Zafar Yongping Song Delong Liu | 2018 | Frontiers of Medicine2018，12，5： | 2 |
| 2 | The role of Nkx3.2 in chondrogenesis显示文摘抄写因素, Nkx3.2,是发展基因的 NK 家庭的一个成员并且在许多哺乳动物的模型有机体在 embryogenesis 期间被表示,包括鸡肉和老鼠。它首先作为风笛(bap ) 基因在果蝇被识别,在在 midgut 肌的形成期间必要被表明了的地方。然而,哺乳动物的相当或相同的事物 Nkx3.2 被显示了起一个重要作用在轴并且手足 skeletogenesis;特别地,人的骨胳的疾病, spondylo-megaepiphyseal-metaphyseal 发育异常(SMMD ) ,与 Nkx3.2 基因的变化被联系。在这评论,我们在肌与骨的开发期间加亮 Nkx3.2 的角色,与在决定 chondrogenic 房间命运的因素角色和它在 endochondral 骨化和 chondrocyte 幸存的随后的角色上的一个重音。 | Roshni S. RAINBOW Heenam KWON Li ZENG | 2014 | Frontiers in Biology2014，9，5： | 2 |
| 3 | Co-supplementation of single and multi doses of vitamins C and E ameliorates cisplatin- induced acute renal failure in mice显示文摘 | AJITH T A ABHISHEK G ROSHNY D | 2009 | Experimental and Toxicologic Pathology2009，61，6： | 1 |
| 4 | Genetic variations at microRNA and processing genes and risk of oral cancer显示文摘 | Roshni Roy Navonil Sarkar Sandip Ghose Ranjan R. Paul Mousumi Pal Chandrika Bhattacharya Shweta K Roy Chowdhury Saurabh Ghosh Bidyut Roy | 2014 | Tumor Biology2014，，4： | 1 |
| 5 | An Investigation of the Variety and Complexity of Statistical Methods Used in Current Internal Medicine Literature显示文摘 | Roshni Narayanan Rebecca Nugent Kenneth Nugent | 2015 | Southern Medical Journal2015，，10： | 1 |
| 6 | Co-supplemen- tation of single and multi doses of vitamins C and E amel- iorates cisplatin-induced acute renal failure in mice 显示文摘 | Ajith TA Abhishek G Roshny D | 2009 | Exp Toxicol Pathol2009，61，6： | 1 |
| 7 | Operative delivery and postnatal depression:a cohort study显示文摘 | Roshni R Patel | 2005 | BJM2005，330，7496： | 1 |
| 8 | Gas attachment of oil droplets for gas flotation for oily wastewater cleanup显示文摘 | Roshni M Richard A D | 2003 | Separation and purification technology2003，33，： | 1 |
| 9 | Gas attachment of oil droplets for gas flotation for oily wastew ater cleanup显示文摘 | ROSHNI M and RICHARD A D | 2003 | Separation and Purifica- tionTechnology2003，33，3： | 1 |
| 10 | Gas attachment of oil droplets for gas flotation for oily wastewater cleanup显示文摘 | Roshni M Richard A D | 2003 | Separation and purification technology2003，33，： | 1 |
| 11 | Consensus-Derived Practice Standards Plan for Complicated Kaposiform Hemangioendothelioma显示文摘 | Beth A. Drolet Cameron C. Trenor Leonardo R. Brand?o Yvonne E. Chiu Robert H. Chun Roshni Dasgupta Maria C. Garzon Adrienne M. Hammill Craig M. Johnson Brook Tlougan Francine Blei Michèle David Ravindhra Elluru Ilona J. Frieden Sheila F. Friedlander Ionel | 2013 | The Journal of Pediatrics2013，，1： | 1 |
| 12 | Cinnamon extract inhibits tau aggregation associated with alzheimer’s disease in vitro显示文摘 | Dylan W P Roshni C G Francesca S | 2009 | Journal of Alzheimer’s Disease2009，，17： | 1 |
| 13 | 右美托咪定对小儿腹腔镜疝修补术后苏醒期躁动的影响显示文摘目的研究给予单剂量右美托咪定对小儿腹腔镜疝修补术后苏醒期躁动的影响。方法60例行腹腔镜下疝修补术、ASA为Ⅰ-Ⅱ级、年龄为1~3岁的小儿。分为3组:在麻醉诱导后,D1组(n=20)静脉注射0.3μg/kg右美托咪定;D2组(n=20)静脉注射0.5μg/kg的右美托咪定;C组(n=20)注射相同容量的生理盐水。静脉注射时间均为10 min。麻醉诱导使用2000~4000μg/kg异丙酚及150~200μg/kg顺式阿曲库铵,1~1.5 MAC七氟醚和0.2μg·kg-1·min-1瑞芬太尼用于麻醉维持。麻醉诱导后所有小儿均静注2000μg/kg曲马多用于防治术后镇痛。结果 D2组术后躁动评分低于对照组(P〈0.05),D1组与对照组无差别。右美托咪定组的心率低于对照组(P〈0.05),其术后追加药物以加强镇静镇痛的需求也较低。三组的术后拔管时间比较无统计学意义。三组均未发生术后恶心、呕吐等不良反应。结论给予单剂量0.5μg/kg的右美托咪定可以有效减少行小儿腹腔镜疝修补术后苏醒期躁动的发生率,且无明显不良反应。 | Diwas Manandhar 叶西就 Roshni shah 许冬妮 卢桠楠 陈瑞霞 | 2015 | 岭南现代临床外科2015，15，6： | 1 |
| 14 | Fabrieation of chitin-chitosan/nano ZrO2 composite scaffolds for tissue engineering applications显示文摘 | Jayakumar R Roshni Ramaehandran Sudheesh Kumar P T | 2011 | Int J Biol Maeromol2011，49，3： | 1 |
| 15 | The Dynamics of Macrophage Infiltration into the Arterial Wall during Atherosclerotic Lesion Development in Low-Density Lipoprotein Receptor Knockout Mice显示文摘 | Dan Ye Ying Zhao Reeni B. Hildebrand Roshni R. Singaraja Michael R. Hayden Theo J.C. Van Berkel Miranda Van Eck | 2011 | The American Journal of Pathology2011，，1： | 1 |
| 16 | Inactivation of Escherichia coli0157:H7 in apple juice and apple cider by trans-cinnamaldehyde显示文摘 | Baskaran Sangeetha Ananda Amalaradjou Mary Anne Roshni Hoagland Thomas | 2010 | Food Microbiology2010，141，12： | 1 |
| 17 | Co-supplementation of single and multi doses of vitamins C and E ameliorates eisplatin-induced acute renal failure in mice显示文摘 | Ajith TA Abhishek G Roshny D | 2009 | Exp Toxicol Pathol2009，61，6： | 1 |
| 18 | Shaping the aetin cytoskeleton using microtubule tips 显示文摘 | Roshni B Fred C | 2007 | Current Opinion in Cell Biology2007，19，1： | 1 |
| 19 | Update on rhabdomyosarcoma 显示文摘 | Roshni Dasgupta | 2012 | Sem Pediat Surge2012，21，： | 1 |
| 20 | Vaccination practices in End Stage Renal Failure and Renal Transplantation; Review of current guidelines and recommendations显示文摘Due to the increased burden of infectious complications following solid organ transplantation, vaccination against common pathogens is a hugely important area of discussion and application in clinical practice. Reduction in infectious complications will help to reduce morbidity and mortality post-transplantation. Immunisation history is invaluable in the work-up of potential recipients. Knowledge of the available vaccines and their use in transplant recipients, donors and healthcare providers is vital in the delivery of quality care to transplant recipients. This article will serve as an aide-memoire to transplant physicians and health care professionals involved in managing transplant recipients as it provides an overview of different types of vaccines, timing of vaccination, vaccines contraindicated post solid organ transplantation and travel vaccines. | Nalaka Gunawansa Roshni Rathore Ajay Sharma Ahmed Halawa | 2018 | World Journal of Transplantation2018，8，3： | 1 |
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