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| 1 | Research on unloading nonlinear mechanical characteristics of jointed rock masses显示文摘Geological environments of rock mass projects are always very complicated, and further investigations on rock mechanical characteristics are needed. There are considerable distinctions in rock mechanical characteristics under unloading and loading conditions. A series of tests are conducted to study the stress-strain relationship of rock masses under loading and unloading conditions. Also, the anisotropy, the size effect, and the rheological property of unloading rock mass are investigated. The tests presented in the paper include model test and granite rheological test, which are conducted considering geological condition, rock mass structure, in-situ stress field of the permanent shiplock of the Three Gorges Project. The main differences between loading and unloading rock masses are stress paths, yield criteria, deformation and strength parameters, etc.. Different structural plane directions affect unloading rock mass evidently. With increasing size, the tensile strength, the compressive strength, the deformation modulus, the Poisson's ratio and the anisotropy of rock mass all decrease. For sandstone samples with parallel bedding planes, the cohesion c increases but the internal friction angle ? decreases under unloading condition when compared with the values under loading condition. While for samples with vertical bedding planes, the trend is adverse. The rheological property of rocks has close relationship with the tensile stresses of rock masses. When the sandstone samples are tested under high stress condition, their rheological properties are very obvious with the unloading of confining pressure, and three typical rheological stages are shown. Rheological rate changes with the variations in axial stress and confining pressure. | Jianlin Li Lehua Wang Xingxia Wang Ruihong Wang Zhuang Cheng Li Dang | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，4： | 15 |
| 2 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
| 3 | Experimental study of photooxidation products of ethylbenzene显示文摘Smog chamber experiments were performed to investigate the composition of products formed from photooxidation of aromatic hydrocarbon ethylbenzene.Vacuum ultraviolet photoionization mass spectrometer and aerosol time-of-flight mass spectrometer were used to measure the products in the gas and particle phases in real-time.Experimental results demonstrated that ethylphenol,methylglyoxal,phenol,benzaldehyde,and 2-ethylfurane were the predominant photooxidation products in both the gas and particle phases.However,there were some dierences between detected gas phase products and those of particle phase,for example,2-ethylfurane,ethylglyoxylic acid,nitroethylbenzene,3,4-dioxopentanal and ethyl-nitrophenol were only existing in the particle-phase. The possible reaction mechanisms leading to these products were also discussed and proposed. | Mingqiang Huang Weijun Zhang Liqing Hao Zhenya Wang Li Fang Ruihong Kong Xiaobin Shan Fuyi Liu Liusi Sheng | 2010 | Journal of Environmental Sciences2010，22，10： | 5 |
| 4 | Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2^(pos)subjects显示文摘Increasing numbers of SARS-CoV-2-positive(SARS-CoV-2^(pos))subjects are detected at silent SARS-CoV-2 infection stage(SSIS).Yet,SSIS represents a poorly examined time-window wherein unknown immunity patterns may contribute to the fate determination towards persistently asymptomatic or overt disease.Here,we retrieved blood samples from 19 asymptomatic and 12 presymptomatic SARS-COV-2^(pos)subjects,47 age/gender-matched patients with mild or moderate COVID-19 and 27 normal subjects,and interrogated them with combined assays of 44-plex CyTOF,RNA-seq and Olink.Notably,both asymptomatic and presymptomatic subjects exhibited numerous readily detectable immunological alterations,while certain parameters including more severely decreased frequencies of CD107a^(low)classical monocytes,intermediate monocytes,non-classical monocytes and CD62L^(hi)CD8^(+)Tnaive cells,reduced plasma STC1 level but an increased frequency of CD4^(+)NKT cells combined to distinguish the latter.Intercorrelation analyses revealed a particular presymptomatic immunotype mainly manifesting as monocytic overactivation and differentiation blockage,a likely lymphocyte exhaustion and immunosuppression,yielding mechanistic insights into SSIS fate determination,which could potentially improve 5ARS-CoV-2 management. | Shanhe Yu Caixia Di Shijun Chen Mingquan Guo Jiayang Yan Zhaoqin Zhu Li Liu Ruixue Feng Yinyin Xie Ruihong Zhang Juan Chen Mengxi Wang Dong Wei Hai Fang Tong Yin Jinyan Huang Saijuan Chen Hongzhou Lu Jiang Zhu Jieming Qu | 2021 | Cell Research2021，31，11： | 4 |
| 5 | Similar Ability of FbaA with M Protein to Elicit Protective Immunity Against Group A Streptococcus Challenge in Mice显示文摘Group A streptococcus(GAS),an important human pathogen,can cause various kinds of infections including superficial infections and potentially lethal infections,and the search for an effective vaccine to prevent GAS infections has been ongoing for many years. This paper compares the immunogenicity and immunoprotection of FbaA(an Fn-binding protein expressed on the surface of GAS) with that of M protein,the best immunogen of GAS. Assay for immune response showed that FbaA,similar to M protein,could induce protein-specific high IgG titer in BALB/c mice. Furthermore,following GAS challenge,the mice immunized with FbaA showed the same protective rate as those with M protein. These results indicate that FbaA is similar in ability to M protein in inducing protective immunity against GAS challenge in mice. | Cuiqing Ma Caihong Li Xiurong Wang Ruihong Zeng Xiaolin Yin Huidong Feng Lin Wei | 2009 | Cellular & Molecular Immunology2009，6，1： | 4 |
| 6 | Effect of Sr on microstructure and aging behavior of Mg-14Li alloys | Bin Jiang a,b,c,Ying Zeng b,Hengmei Yin a,b,Ruihong Li a,b,Fusheng Pan a,b a National Engineering Research Center for Magnesium Alloys,Chongqing University,Chongqing 400030,China b College of Materials Science and Engineering,Chongqing University,Chongqing 400030,China c New Materials Center,Chongqing Academy of Science and Technology,Chongqing 401123,China | 2012 | Progress in Natural Science:Materials International2012，22，2： | 3 |
| 7 | Drought tolerance evaluation of tobacco plants transformed with different set of genes under laboratory and field conditions显示文摘尽管广泛的研究证明了许多干旱应答的基因授与干旱忍耐到植物,能力在各种各样的自然条件下面由不同基因授与的干旱忍耐的比较很少有报导。我们评估了并且比较 transgenes,干旱应答的基因(AtDREB1B 和 AtCBL1 ) 和根的二个集合的效果调整建筑学的基因(iaaM 和 AtCKX ) ,在在 Nicotiana tabacum 的干旱忍耐上,植物使遭到了到不同条件。根特定的倡导者 PYK10 驾驶的 AtCKX3 的表示(此后指定了为 P10;P10 : AtCKX3 ) , 35S:AtCKX3,或 P10:iaaM 支持了根生长和开发。比作怀有 P10 的植物: 展出的 AtCKX3, 35S:AtCKX3, P10:iaaM,或空向量,那些带的 35S:AtDREB1B, 35S:AtCBL1,或 35S:iaaM 在控制实验室的条件下面增加了干旱忍耐。相反地,在地里,条件,与 35S:AtDREB1 转变的植物, 35S:AtCBL1,或 35S:iaaM 对干旱应力敏感。在地条件下面,干旱应力戏剧性地减少了生长和而它在带 P10 的植物上有小效果,怀有 35S:AtDREB1B, 35S:AtCBL1, 35S:iaaM,或空向量的植物的种子生产: AtCKX3, 35S:AtCKX3,或 P10:iaaM。这研究证明到有环境条件的干旱压力变化的植物忍耐,和我们的结果显示操作控制根建筑学的基因的表示可能为处于自然条件与改进干旱忍耐设计植物是重要的。 | Yuanhua Wang Ruihong Dang Jinxi Li Yu Han Ning Ding Xingliang Li Meiru Jia Ziqiang Li Lingzhi Wei Jinzhu Jiang Yijuan Fan Bingbing Li Wensuo Jia | 2015 | Science Bulletin2015，60，6： | 3 |
| 8 | Microstructure and mechanical properties of Mg-14Li-1Al-0.3La alloys produced by two-pass extrusion显示文摘The microstructure of as-cast and extruded Mg-14 Li-1 Al-(0, 0.3) La alloys was examined with XRD,OM, SEM, and EDS. The mechanical properties of the extruded specimens with and without La were compared. The results show that La addition has an obvious effect on the microstructure of the as-cast LA141 alloy by reducing the average grain size from 600 to 220 μm. β-Li and LiMgAl_2 phases are observed in both alloys, and long-rod-shaped Al_2 La phase is also observed in the La containing alloy. After extrusion, Al_2 La phases are short-rod-shaped and distribute evenly in the alloy. LAl41-0.3 La alloy has higher elongation(34%), which is attributed to refined microstructure and weak texture due to shortrod-like Al_2 La phase. | Ruihong Li Bin Jiang Zhijun Chen Fusheng Pan Zhanyong Gao | 2017 | Journal of Rare Earths2017，35，12： | 3 |
| 9 | The effect of carbon nanotubes on osteogenic functions of adipose-derived mesenchymal stem cells in vitro and bone formation in vivo compared with that of nano-hydroxyapatite and the possible mechanism显示文摘It has been well recognized that the development and use of artificial materials with high osteogenic ability is one of the most promising means to replace bone grafting that has exhibited various negative effects.The biomimetic features and unique physiochemical properties of nanomaterials play important roles in stimulating cellular functions and guiding tissue regeneration.But efficacy degree of some nanomaterials to promote specific tissue formation is still not clear.We hereby comparatively studied the osteogenic ability of our treated multiwalled carbon nanotubes(MCNTs)and the main inorganic mineral component of natural bone,nano-hydroxyapatite(nHA)in the same system,and tried to tell the related mechanism.In vitro culture of human adiposederived mesenchymal stem cells(HASCs)on the MCNTs and nHA demonstrated that although there was no significant difference in the cell adhesion amount between on the MCNTs and nHA,the cell attachment strength and proliferation on the MCNTs were better.Most importantly,the MCNTs could induce osteogenic differentiation of the HASCs better than the nHA,the possible mechanism of which was found to be that the MCNTs could activate Notch involved signaling pathways by concentrating more proteins,including specific bone-inducing ones.Moreover,the MCNTs could induce ectopic bone formation in vivo while the nHA could not,which might be because MCNTs could stimulate inducible cells in tissues to form inductive bone better than nHA by concentrating more proteins including specific bone-inducing ones secreted from M2 macrophages.Therefore,MCNTs might be more effective materials for accelerating bone formation even than nHA. | Zhipo Du Xinxing Feng Guangxiu Cao Zhending She Rongwei Tan Katerina E.Aifantis Ruihong Zhang Xiaoming Li | 2021 | Bioactive Materials2021，6，2： | 3 |
| 10 | Mixture prepared with Chinese medicines in terms of releasing exterior cold and clearing interior heat: its efficacy and safety in patients with seasonal influenza-a randomized controlled trial显示文摘OBJECTIVE: To assess the efficacy and safety in 105 patients with seasonal Influenza in Beijing, the mixture prepared with Chinese medicines follows the treatment regimen of releasing exterior cold andclearing interior heat.METHODS: Total 330 patients with seasonal influenza were enrolled and randomly and averagely divided into the Chinese herbal medicine, the western medicine and the Chinese patent medicine group. They were treated with Chinese medicine Oseltamivir Phosphate Capsules and the Scattering Wind and Resolving Toxins Capsules. The main efficacy indicators were the antifebrile onset time and recovery time of body temperature. The efficacy and safety of the mixture was scientifically evaluated. Comparisons of several variables were analyzed.RESULTS: Median antifebrile onset time of the Chinese herbal medicine group was significantly shorter than the western medicine group(P < 0.05) and the Chinese patent medicine group(P < 0.05). The median antifebrile recovery time of the Chinese herbal medicine group was significantly shorter than the Chinese patent medicine group(P <0.05). The groups evaluated by TCM symptom pattern effect, both the Chinese herbal medicine group and Western Medicine group were better than the Chinese patent medicine group(P <0.05). The disappearance rate of main symptoms and some minor symptom patterns of the Chinese herbal medicine group were higher than the other 2 groups.CONCLUSION: The mixture of releasing exterior cold and clearing interior heat could significantly shorten the fever time with safety. | Wu Zhisong Li Guodong Wei Wan Liu Zhaoheng Wang Wei Ma Ruihong Liu Wenhong Ma Jiaju Wang Yuguang Jiao Yang | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 3 |
| 11 | Photocatalytic Oxidation Kinetics of Thiophene with Nano-F^-/Fe^(3+)/TiO_2显示文摘Photocatalytic oxidation kinetics of thiophene in n-octane/water extraction system was studied with fluorine and ferric ion codoped nano-TiO2(nano-F-/Fe3+/TiO2) powders used as the photocatalyst.Effects of initial concentration of thiophene and additional dosage of F-/Fe3+/TiO2 on the reaction rate constant and half-life were investigated.The results showed that the appropriately added dosage of F-/Fe3+/TiO2 was 0.1 g in the 100-mL reaction system and the photooxidative kinetics of thiophene in the presence of F-/Fe3+/TiO2 catalyst was of first-order with a rate constant of 0.6508 h-1 and a half-life of 1.0651 h.The desulfurization rate of thiophene was 98.1%in 5 h and the sulfur content could be reduced from 800 ppm to 15 ppm.The reaction rate constant increased with a decreasing initial concentration of thiophene. | Li Fatang~1 Sun Zhimin~1 Liu Ying~1 Zhao Dishun~2 Liu Ruihong~1 (1.College of Science,Hebei University of Science and Technology,Shijiazhuang 050018 2.College of Chemical and Pharmaceutical Engineering,Hebei University of Science and Technology) | 2009 | China Petroleum Processing & Petrochemical Technology2009，11，4： | 2 |
| 12 | Effect of Mg 24 Y 5 intermetallic particles on grain refinement of Mg-9Li alloy显示文摘 | Ying Zeng Bin Jiang Mingxing Zhang Hengmei Yin Ruihong Li Fusheng Pan | 2014 | Intermetallics2014，，： | 1 |
| 13 | Compositional changes of cottonseed hull substrate during P. ostreatus growth and the effects on the feeding value of the spent substrate显示文摘 | Xiujin Li Yunzhi Pang Ruihong Zhang | 2001 | Bioresource Technology2001，，2： | 1 |
| 14 | Oyster mushroom cultiva- tionwith rice andwheat straw显示文摘 | RUIHONG ZHANG XIUJ]N LI J G FADEL | 2002 | BioresourceTechnology2002，，82： | 1 |
| 15 | Biogas production from co-digestion of corn stover and chicken manure under anaerobic wet, hemi-solid, and solid state conditions 显示文摘 | LI Yeqing ZHANG Ruihong CHEN Chang | 2013 | Bioresource Technology2013，149，： | 1 |
| 16 | Characteristics of dairy manure composting with rice straw显示文摘 | Li Xiujin Zhang Ruihong Pang Yunzhi | 2008 | Bioresource Technology2008，99，： | 1 |
| 17 | Anaerobic codigestion of chicken manure and corn stover in batch and continuously stirred tank reactor(CSTR)显示文摘 | Li Yeqing Zhang Ruihong He Yanfeng | 2014 | Bioresource Technology2014，156，： | 1 |
| 18 | Adaptive output-feedback control for MIMO nonlinear systems with time-varying delays using neural networks显示文摘An adaptive neural network output-feedback regulation approach is proposed for a class of multi-input-multi-output nonlinear time-varying delayed systems.Both the designed observer and controller are free from time delays.Different from the existing results,this paper need not the assumption that the upper bounding functions of time-delay terms are known,and only a neural network is employed to compensate for all the upper bounding functions of time-delay terms,so the designed controller procedure is more simplified.In addition,the resulting closed-loop system is proved to be semi-globally ultimately uniformly bounded,and the output regulation error converges to a small residual set around the origin.Two simulation examples are provided to verify the effectiveness of control scheme. | Weisheng Chen Ruihong Li | 2010 | Journal of Systems Engineering and Electronics2010，21，5： | 1 |
| 19 | Characterietics of dairy manure composting with rice staw 显示文摘 | Xiujin Li Ruihong Zhang Yunzhi Pang | 2008 | Bioresource Technology2008，，99： | 1 |
| 20 | Oyster mushroom cultivation with rice and wheat straw 显示文摘 | Ruihong Zhang Xiujin Li J G Fadel | 2002 | Bioresotrrce Technology2002，82，： | 1 |
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