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| 1 | Function of apoptosis and expression of the proteins Bcl-2,p53 and C-myc in the development of gastric cancer显示文摘INTRODUCTIONIn China ,the incidence and mortality of gastric cancer rank the second among all cancers. Recent development of cancer [1-20].The aim of this study was investigat the insight of apoptosis and bcl-2, p53 and C-myc protein expression in the development of gastric cancer . | An Gao Xu Shao Guang Li Ji Hong Liu Ai Hua Gan Research Laboratory of Digestive Disease,Huizhou Central People’s Hospital,Huizhou 516001,Guangdong Province,ChinaDr.An Gao Xu graduated from Guangdong Medical College in 1984.He is an associate physician-in-chief,specializing in the research and treatment of gastrointestinal and liver tumors.He has published 24 papers and 1 book. | 2001 | World Journal of Gastroenterology2001，7，3： | 91 |
| 2 | 2型糖尿病患者个体化血糖控制目标和药物治疗显示文摘'有效管理糖尿病全球合作组织'(下称'糖尿病全球合作组织')成立的宗旨是为临床提供实用指南以改善糖尿病患者的预后,制定并修改相关策略以改善T2DM患者血糖控制情况。糖尿病全球合作组织提倡对糖尿病患者实行个体化治疗方案,明确需要特殊考虑T2DM患者亚组人群。这篇文章基于此前发表的文献,扩大了实用指南的范围,包括有并发症的新诊断T2DM患者和妊娠期糖尿病(GDM)患者。良好血糖控制是T2DM管理的基石,在预防或延缓糖尿病并发症的发生、发展过程中发挥重要作用。个体化治疗目标和安全及时的血糖达标治疗方案至关重要。另外,还需制定更全面的护理计划以降低心血管风险和改善患者预后。 | 张晓梅 纪立农 Bailey CJ Aschner P Stefano Del Prato LaSalle J JI Li-nong Matthaei S | 2014 | 中国糖尿病杂志2014，22，10： | 16 |
| 3 | 1990—2017年中国伤害负担:2017年全球疾病负担研究结果(摘译)显示文摘伤害是全球性的公共卫生挑战,涉及各年龄组和不同性别的人群。过去三十年来,中国经济快速发展,人口老龄化趋势加重,社会呈现出城镇化、机动化和老龄化等特征。随着人们生活环境和生活方式的改变,伤害已跃居人群致死原因第五位,仅排在恶性肿瘤、心脑血管疾病、呼吸系统疾病和心肌梗死之后。据估计,中国每年在伤害方面消耗的直接医疗费用约为650亿元人民币. | 林泽婷(译) 吕来文(译) 黄晓晴(译) 李丽萍(审校) Duan Leilei Ye Pengpeng Juanita A Haagsma Jin Ye Wang Yuan Er Yuliang Deng Xiao Gao Xin Ji Cuirong Wang Linhong Marlena S Bannick W Cli Mountjoy-Venning Caitlin N Hawley Zichen Liu Mari Smith Spencer L James Theo Vos Christopher J L Murray | 2020 | 伤害医学(电子版)2020，9，2： | 15 |
| 4 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 5 | Plasma endothelin in patients with endotoxemia and dynamic comparison between vasoconstrictor and vasodilator in cirrhotic patients显示文摘INTRODUCTIONPortal hypertension is a common clinical syndromecharacterized by an abnormal increase in portalblood to the systemic circulation, bypassing theliver. Recent studies have reported that humoralsubstances play an important role in thepathogenesis of portal hypertension, either byincreasing vascular resistance at both theintrahepatic and porto-collateral sites or affectingsplanchnic vasodilation with a concomitant increasein parto-collateral blood flow[1-6] | Feng Liu1 Ji Xin Li2, Chun Mei Li2 Xi Sheng Leng2 1Department of General Surgery, the Fifth Affiliated Hospital, Harbin Medical University, Harbin 150036, Heilongjiang Province, China2Department of General Surgery, People’s Hospital, Medical University, Beijing 100044, China | 2001 | World Journal of Gastroenterology2001，7，1： | 8 |
| 6 | Vein transplantation using human umbilical cord blood stem cells in the treatment of stroke sequela显示文摘BACKGROUND: Transplanted mononuclear cell(MNC)of umbilical blood can survive in central nervous system (CNS)of host through blood brain barrier,differentiate into nerver cells,migrate to damaged site and integrate morphological strucgh and function with nerve cells of host so as to improve deficiencies of sensatory function,motor function and cognitive function and influence on stroke sequela.OBJECTIVE: To observe the vein transplantation of human umbilical cord blood stem cells(HUCBSC) for improving neurological function,limb funtion and activity of daily living of patients with stroke and evaluate the reliability.DESIGN: Self-controlled study.SETTING: Department of Neurosurgery,the Second People's Hospital of Zhengzhou City;Red-crossed Blood Center of Henan Province;Department of Neurosurgery,the Fist Affiliated Hospital of Zhenzhou University.PARTICIPANTS:A total of 10 patients with stoke sequela were selected from Department of Cerebral Surgery,the Second People's Hospital of Zhengzhou City from April to December 2005.There were 9males and 1 female aged from 35to 75years with the mean age of 56 years.All of them were diagnosed with CT and MRI examination and coincidence with diagnostic criteria of stroke established by the Fourth National Academic Meeting for Cerebrovascular Disease.All patients provided informed consent. METHODS:80-140 mL umbilical blood of term birth of newborn was selected hermetically and maintained in sterile plastic bag.And then,the blood was centrifugated at the speed of 1500 r/min for 30 minutes at 22℃ in order to separate MNC,i.e.,HUCBSC.In addition,after final diagnosis during hospitalization,stroke patients were perfused with HUCBSC through superficial vein of back of the hand.Each patient was averagely penfused with 6 portions of HUCBSC(cellular numbers≥1×108/portion)and the interval between each portion was 1-7 days with the mean interval of 4 days.MAIN OUTCOME MEASURES: ①Neurological function of stroke patients was evaluated with neurological function deficiency(NFD)before treatment and at 3 months after treatment.The scale includes consciousness,level fix function.facial paralysis,language,muscle force of upper limbs,muscle force of lower limb and step function.The total scores ranged from 0 to 45; meanwhile,the lower the scores were,the better the neurological function of limbs was. ②Motor function of injured limbs was evaluated with Fugl-Meyer Assessment (FMA),including motor function of upper limbs.motor function of lower limbs,balance ability,sensory function and motion of joint.The total scores ranged from 0 to 226;meanwhile,the higher the scores were,the better the motor function of limbs was.③Activities of daily living(ADL)was evaluated with Barthel Index(BI),including having meals,taking a bath,dressing oneself,putting on clothes,walking in balance and stair activity.The total scores ranged from 0 to 100;meanwhile,the higher the scores were,the stronger the ADL was.RESULTS:A total of 10 patients were involved in the final analysis.After treatment,NFD of stroke patients was (10.9±5.09)points,which was lower than that before treatment[(25.4±6.09)points,t=8.213,P<0.01].In addition,after treatment,FMA and BI of stroke patients were(80.9±25.00)points and(81.1±15.93)points,re spectively,which were higher than those before treatment[(31.9+21.85)points,(36.2+19.41)points,t=13.024,13.670,P<0.01]. Immuno-suppressive drugs were not used during the whole therapeutic procedure;moreover,immunological rejection and allergic reaction were not observed during the same period.CONCLUSION:Transplanting HUCBSC through superficial vein of back of the hand is regarded as a simple and safe method for the treatment of stroke sequela. | Yong Man1, Jianbin Li2, Bo Yang3, Ji Ma1 1Department of Cerebral Surgery, the Second People’s Hospital of Zhengzhou, Zhengzhou 450000, Henan Province, China 2Red Cross Blood Center of Henan Province, Zhengzhou 450000, Henan Province, China 3Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, Henan Province, China | 2006 | Neural Regeneration Research2006，1，7： | 7 |
| 7 | Tensile properties and fracture behavior of Ti_2AlNb based alloys at room temperature显示文摘The tensile mechanical properties and fracture behaviors of Ti 22Al 20Nb 7Ta alloys were studied at room temperature. Three typical microstructures of Ti 2AlNb based alloys were obtained by combination of thermal mechanical processing and heat treat ment. They are: 1) lath mixture of O + B 2 with remaining β grain boundaries and α 2 phase; 2) equiaxed O phase in B 2 matrix; 3) fine lath mixture of O + B 2 without remaining β grain boundaries. It is shown that the microstructure obviously affects the tensile properties of Ti 2AlNb based alloys. The microstructure of fine lath mixture of O + B 2 without remaining β grain boundaries has good combination of yield stress and ductility, while the microstructure with lath mixture of O + B 2 with remaining β grain boundaries and α 2 phase has low yield stress and elongation. The fracture mode was also controlled by the microstructure of Ti 2AlNb based alloys. By means of SEM, it was found that the dominated fracture mode of microstructure with lath mixture of O + B 2 with remained β grain boundary and α 2 phase was intergranular, and the fracture mode of the other two microstructures was mainly transgranular. | PENG Ji hua(彭继华) 1, 2 , MAO Yong(毛 勇) 2, LI Shi qiong(李世琼) 2, SUN Xun fang(孙训方) 2 1. Department of Engineering Mechanics, Southwest Jiaotong University, Chengdu 610031, P.R.China 2. Division of Super Alloys, Central Iron and S | 2000 | 中国有色金属学会会刊:英文版2000，10，3： | 6 |
| 8 | HEMOPERFUSION IN THE MANAGEMENT OF PATIENTS SEVERELY POISONED BY ORGANOPHOSPHORUS显示文摘 | Mao Yuying XuZhougyi(Zhu ji people’s Hosptal,Zhe jiang province,Chine) | 1997 | Chinese Journal of Biomedical Engineering(English Edition)1997，6，4： | 5 |
| 9 | Development of a script of phonemically balanced monosyllable lists of Mandarin-Chinese显示文摘Objectives To develop a set of monosyllable audiometry test material that can be used in speech recognition testing in Mandarin Chinese. Materials and Methods In an effort to improve reliability and efficiency in clinical practice, a set of 30 test lists of 25 monosyllable test items each was designed with consideration of the following: length of the list, phonemical balance (PB), word utility frequency, coverage of common words, and equivalency among lists. The 30 lists contained 750 monosyllabic words and were constructed on the basis of Chinese phoneme distribution probability summarized in the Manual of Acoustic. The occurrence incidence of the 22 consonants, 36 vowels, and 4 tones of the Chinese Mandarin characters in the 30 test lists were calculated. To achieve PB, 489 monosyllables were selected from the 2500 most commonly used Chinese characters and the 4000 most commonly used Chinese phrases to compile the 30 monosyllable test lists using a computer algorithm with manual adjustment. Results Thirty phonemical balanced word lists of common Mandarin Chinese monosyllabic words were compiled. Each list consisted of 25 monosyllables. A total of 489 phonemes (consonants, vowels and tones) were included in the set. Conclusions This set of lists can potentially be used as the basic lists for future development of Mandarin PB monosyllable speech test materials. | JI Fei, CHEN Aiting, ZHAO Yang, XI Xin, HAN Dongyi Departments of Otorhinolaryngology-Head and Neck Surgery, Institute of Otorhinolaryngology, General Hospital of People’s Liberation Army, Beijing 100853, China | 2010 | Journal of Otology2010，5，1： | 4 |
| 10 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘 | Craig S Anderson Yining Huang Ji Guang Wang Hisatomi Arima Bruce Neal Bin Peng Emma Heeley Christian Skulina Mark W Parsons Jong Sung Kim Qing Ling Tao Yue Chun Li Jian Dong Jiang Li Wen Tai Jin Li Zhang En Xu Yan Cheng Stephane Heritier Lewis B Morgenste | 2008 | Lancet Neurology2008，，5： | 4 |
| 11 | Further geological and palaeoanthropological investigations at the Maludong hominin site, Yunnan Province, Southwest China显示文摘Three-dimensional mapping and section work undertaken by us in 2008 have identified 11 stratigraphic units at Maludong site.AMS radiocarbon dating of charcoal established an accurate and internally consistent age profile for the sequence of 17.8±0.2 ka to 13.2±0.1 ka.Archaeomagnetic analysis showed changes in externally derived pedogenically enhanced material consistent with a warming in climate between the cold period of Henrich Event 1 and the B lling-Aller d interstadial.Human remains recovered during the 1989 excavation were derived from a deposit dating to this interstadial,or between 14.3±0.3 ka and 13.5±0.1 ka.Anthropogenic features,including burnt rocks,baked sediment and thick charcoal and ash layers,were identified and examined through archaeomagnetic analysis.Two monkey fossils are described here,one of them being reassigned from Macaca robustus to M.aff.M.assamensis.They confirm the young age of the site and also show signs of anthropogenic alteration in the form of burning.Additional human cranial remains are reported for the first time and new data are provided for some specimens described previously.A range of new features is identified that strengthen the affinities of the Maludong remains to archaic humans.The presence of this globally unique mosaic of archaic and modern features raises important questions about human evolutionary history in East Asia during the Late Upper Pleistocene. | JI XuePing CURNOE Darren BAO ZhenDe HERRIES Andy I R FINK David ZHU YunSheng HELLSTROM John LUO Yun TACON Paul S C | 2013 | Chinese Science Bulletin2013，58，35： | 3 |
| 12 | Typical Survey and Research on Returning-home Migrant Workers' Entrepreneurship in Jiangxi Province under Post-financial Crisis显示文摘In order to study the entrepreneurship situation of Jiangxi return migrant workers after the financial crisis,we have conducted a survey on 107 entrepreneurial return migrant workers in 6 counties of Jiangxi Province.The results show that the return of migrant workers is mainly attributed to personal factors,while social factors are also very important.The major difficulties facing return migrant workers are the funding difficulties,complicated formalities to start a business,difficulty in safeguarding their rights and interests,their own low quality and so on.The support needed by the return migrant workers from the government is manifested in five aspects,say,to improve the service and management for the entrepreneurship of migrant workers,to provide financing policy support,to increase the preferential fiscal and taxation policies,to enhance the entrepreneurship training and to provide preference for the return migrant workers to use land. | OUYANG Zhang-sun1,ZHANG Xin-zhi2,WANG Run-qun3,LUO Feng1,SHEN Ai-guo1,WU Xing-lin1 1.Jiangxi Biotech Vocational College,Nanchang 330299,China 2.The Research Center of the Central China’s Economic Development,Nanchang University,Nanchang 330047,China 3.Jizhou Agricultural Bureau,Jizhou District,Ji’an City in Jiangxi Province,Ji’an 343000,China | 2010 | Asian Agricultural Research2010，2，10： | 2 |
| 13 | Arterial Stiffness Is Regulated by Nitric Oxide and Endothelium-Derived Hyperpolarizing Factor During Changes in Blood Flow in Humans显示文摘 | Jeremy Bellien Julie Favre Michele Iacob Ji Gao Christian Thuillez Vincent Richard Robinson Joannidès | 2010 | Hypertension2010，，3： | 2 |
| 14 | Immuno-histochemical analysis of Bcl-2, Bax, Bcl-X, and mcl-1 expression in prostate cancers显示文摘 | Krajewska M Krajewski S Epstein JI | 1996 | Am J Pathol1996，148，： | 2 |
| 15 | On the preparation of amorphous Mg-Ni alloys by mechanical alloying 显示文摘 | Ji S J Sun J C Yu Z W | 1999 | International Journal of Hydrogen Energy1999，24，： | 2 |
| 16 | Cryopreservation of kunming mouse oocytes using slow cooling, ultrarapid cooling and vitrifyication protocols显示文摘 | Men H S Chen J C Ji W Z | 1997 | Theriogenology1997，47，： | 2 |
| 17 | High order symplectic schemes for the sine-Gordon equation显示文摘 | Wang Y S Wang B Ji Z Z | 2003 | Journal of the Physics of Japan2003，72，11： | 2 |
| 18 | Ginseng pharmacology显示文摘 | Anoja S Attele Ji An Wu Chun-Su Yuan | 1999 | Biochemical Pharmacology1999，，11： | 2 |
| 19 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 20 | Adaptive output-feedback tracking of stochastic nonlinear systems显示文摘 | Ji H B Xi H S | 2006 | IEEE Transactions on Automatic Control2006，51，2： | 1 |
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