|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKca channels and reducing intracellular Ca2+ levels显示文摘 | Xiang-yun GAI Yu-hai WEI Wei ZHANG Ta-na WUREN Ya-ping WANG Zhan-qiang LI Shou LIU Lan MA Dian-xiang LU Yi ZHOU Ri-li GE | 2015 | Acta Pharmacologica Sinica2015，36，5： | 11 |
| 2 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 3 | Recovery of the alografted smalintestine functions显示文摘RecoveryofthealograftedsmalintestinefunctionsJIANGZhiWei,LIJieShou,LINin,LIYouSheng,LIUFangLan,SHENGXueQinandCHENGYong... | JIANG Zhi Wei, LI Jie Shou, LI Nin, LI You Sheng, LIU Fang Lan, SHENG Xue Qin and CHENG Yong Min Subject headings Nutritional support small intestine/transplantation small intestine/physiopathology | 1997 | World Journal of Gastroenterology1997，3，2： | 2 |
| 4 | In Situ Acquisition of Equivalent Circuit Parameters of Crystal Resonance during Copper Deposition and Dissolution in Acidic Solution by Electrochemical Quartz Crystal Impedance System显示文摘Thequartzcrystalimpedancetechniqueisapowerfulmethodtocharacterizecrystalresonancesincemultipleinformationaboutcrystalresonanceincludingtheresonantfrequencyandchangesinsomephysicaland/orchemicalpropertiesofthetestsystemcanFigure1.Equivalentelectricalc... | Qing Ji XIE Xiao Lian SUN Xiao Lan GU Hong Wei LIU You Yu ZHANG Shou Zhuo YAO(Chemical Research Institute. Hunan Normal University,Changsha 410081)(Chemistry Department,Hunan Normal University, Changsha 410081) | 1999 | Chinese Chemical Letters1999，10，1： | 1 |
| 5 | Time Series and Spatial Epidemiological Analysis of the Prevalence of Iodine Deficiency Disorders in China显示文摘Objective To recognize the spatial and temporal characteristics of iodine deficiency disorders(IDD),China national IDD surveillance data for the years of 1995–2018 were analyzed.Methods Time series analysis was used to describe and predict the IDD related indicators,and spatial analysis was used to analyze the spatial distribution of salt iodine levels.Results In China,the median urinary iodine concentration increased in 1995–1997,then decreased to adequate levels,and are expected to remain appropriate in 2019–2022.The goiter rate continually decreased and is expected to be maintained at a low level.Since 2002,the coverage rates of iodized salt and the consumption rates of qualified iodized salt(the percentage of qualified iodized salt in all tested salt) increased and began to decline in 2012;they are expected to continue to decrease.Spatial epidemiological analysis indicated a positive spatial correlation in 2016–2018 and revealed feature regarding the spatial distribution of salt related indicators in coastal areas and areas near iodine-excess areas.Conclusions Iodine nutrition in China showed gradual improvements.However,a recent decline has been observed in some areas following changes in the iodized salt supply in China.In the future,more regulations regarding salt management should be issued to strengthen IDD control and prevention measures,and avoid the recurrence of IDD. | FAN Li Jun GAO Yun Yan MENG Fan Gang LIU Chang LIU Lan Chun DU Yang LIU Li Xiang LI Ming SU Xiao Hui LIU Shou Jun LIU Peng | 2022 | Biomedical and Environmental Sciences2022，35，8： | 1 |
| 6 | Enantioselective Palladium‐Catalyzed Insertion of α‐Aryl‐α‐diazoacetates into the O?H Bonds of Phenols<link href='#nss'/>显示文摘 | Xiu‐Lan Xie Shou‐Fei Zhu Jun‐Xia Guo Yan Cai Qi‐Lin Zhou | 2014 | Angew Chem Int Ed2014，，11： | 1 |
| 7 | Apoptosis in immune cells induced by fission fragment ^(147)Pm显示文摘Apoptosisinimmunecelsinducedbyfisionfragment147PmZhuShouPeng,ZhangLanShengandFuQiang(SuzhouMedicalColege,Suzhou215007)Abst... | Zhu Shou Peng, Zhang Lan Sheng and Fu Qiang ( Suzhou Medical College, Suzhou 215007 ) | 1997 | Nuclear Science and Techniques1997，8，4： | 1 |
| 8 | Enhanced oral bioavailability and anti‐tumour effect of paclitaxel by 20(s)‐ginsenoside Rg3 in vivo显示文摘 | Lei‐Qiong Yang Bin Wang Hui Gan Shou‐Ting Fu Xiao‐Xia Zhu Zhuo‐Na Wu Da‐Wei Zhan Ruo‐Lan Gu Gui‐Fang Dou Zhi‐Yun Meng | 2012 | Biopharm Drug Dispos2012，，8： | 1 |
| 9 | High-energy-density plasma in femtosecond-laser-irradiated nanowire-array targets for nuclear reactions显示文摘In this work,the high-energy-density plasmas(HEDP)evolved from joule-class-femtosecond-laser-irradiated nanowire-array(NWA)targets were numerically and experimentally studied.The results of particle-in-cell simulations indicate that ions accelerated in the sheath field around the surfaces of the nanowires are eventually confined in a plasma,contributing most to the high energy densities.The protons emitted from the front surfaces of the NWA targets provide rich information about the interactions that occur.We give the electron and ion energy densities for broad target parameter ranges.The ion energy densities from NWA targets were found to be an order of magnitude higher than those from planar targets,and the volume of the HEDP was several-fold greater.At optimal target parameters,8%of the laser energy can be converted to confined protons,and this results in ion energy densities at the GJ/cm^(3) level.In the experiments,the measured energy of the emitted protons reached 4 MeV,and the changes in energy with the NWA’s parameters were found to fit the simulation results well.Experimental measurements of neutrons from 2H(d,n)3He fusion with a yield of(24±18)×10^(6)/J from deuterated polyethylene NWA targets also confirmed these results. | Defeng Kong Guoqiang Zhang Yinren Shou Shirui Xu Zhusong Mei Zhengxuan Cao Zhuo Pan Pengjie Wang Guijun Qi Yao Lou Zhiguo Ma Haoyang Lan Wenzhao Wang Yunhui Li Peter Rubovic Martin Veselsky Aldo Bonasera Jiarui Zhao Yixing Geng Yanying Zhao Changbo Fu Wen Luo Yugang Ma Xueqing Yan Wenjun Ma | 2022 | Matter and Radiation at Extremes2022，7，6： | 1 |
| 10 | COMPUTATIONS FOR PLANE TURBULENT IMPINGING JET IN CROSS FLOW显示文摘NOMENCLATUREa1anda2 constantsin(14)bhalfwidthwhereu=um2c1,c2andcμconstantsofkεmodelsf1andf2functionsmarkin(13)Hthedepthoftheflumef?.. | Qi Mei lan, Fu Ren shou, Chen Zhi cong Dep. of Hydr. Eng., Tsinghua Univ., Beijing 100084, P.R.China | 1999 | Journal of Hydrodynamics1999，11，4： | 1 |
| 11 | A brain structural connectivity biomarker for autism spectrum disorder diagnosis in early childhood显示文摘Background:Autism spectrum disorder(ASD)is associated with altered brain development,but it is unclear which specific structural changes may serve as potential diagnostic markers,particularly in young children at the age when symptoms become fully estab-lished.Furthermore,such brain markers need to meet the requirements of precision medicine and be accurate in aiding diagnosis at an individual rather than only a group level.Objective:This study aimed to identify and model brain-wide differences in structural connectivity using diffusion tensor imaging(DTI)in young ASD and typically developing(TD)children.Methods:A discovery cohort including 93 ASD and 26 TD children and two independent validation cohorts including 12 ASD and 9 TD children from three different cities in China were included.Brain-wide(294 regions)structural connectivity was measured using DTI(fractional anisotropy,FA)together with symptom severity and cognitive development.A connection matrix was constructed for each child for comparisons between ASD and TD groups.Pattern classification was performed on the discovery dataset and the resulting model was tested on the two independent validation datasets.Results:Thirty-three structural connections showed increased FA in ASD compared to TD children and associated with both autistic symptom severity and impaired general cognitive development.The majority(29/33)involved the frontal lobe and comprised five different networks with functional relevance to default mode,motor control,social recognition,language and reward.Overall,clas-sification achieved very high accuracy of 96.77%in the discovery dataset,and 91.67%and 88.89%in the two independent validation datasets.Conclusions:Identified structural connectivity differences primarily involving the frontal cortex can very accurately distinguish novel individual ASD from TD children and may therefore represent a robust early brain biomarker which can address the requirements of precision medicine. | Xi Jiang Xiao-Jing Shou Zhongbo Zhao Yuzhong Chen Fan-Chao Meng Jiao Le Tian-Jia Song Xin-Jie Xu Weitong Guo Xiaoyan Ke Xiao-E Cai Weihua Zhao Juan Kou Ran Huo Ying Liu Hui-Shu Yuan Yan Xing Ji-Sheng Han Song-Ping Han Yun Li Hua Lai Lan Zhang Mei-Xiang Jia Jing Liu Xuan Liu Keith M.Kendrick Rong Zhang | 2023 | Psychoradiology2023，3，1： | 0 |
| 12 | Dual-Driven Hemostats Featured with Puncturing Erythrocytes for Severe Bleeding in Complex Wounds显示文摘Achieving rapid hemostasis in complex and deep wounds with secluded hemorrhagic sites is still a challenge because of the difficulty in delivering hemostats to these sites.In this study,a Janus particle,SEC-Fe@CaT with dual-driven forces,bubble-driving,and magnetic field–(MF–)mediated driving,was prepared via in situ loading of Fe_(3)O_(4) on a sunflower sporopollenin exine capsule(SEC),and followed by growth of flower-shaped CaCO3 clusters.The bubble-driving forces enabled SEC-Fe@CaT to self-diffuse in the blood to eliminate agglomeration,and the MF-mediated driving force facilitated the SEC-Fe@CaT countercurrent against blood to access deep bleeding sites in the wounds.During the movement in blood flow,the meteor hammer-like SEC from SEC-Fe@CaT can puncture red blood cells(RBCs)to release procoagulants,thus promoting activation of platelet and rapid hemostasis.Animal tests suggested that SEC-Fe@CaT stopped bleeding in as short as 30 and 45 s in femoral artery and liver hemorrhage models,respectively.In contrast,the similar commercial product Celox™required approximately 70 s to stop the bleeding in both bleeding modes.This study demonstrates a new hemostat platform for rapid hemostasis in deep and complex wounds.It was the first attempt integrating geometric structure of sunflower pollen with dual-driven movement in hemostasis. | Haoyu Qiu Guangqian Lan Weiwei Ding Xinyu Wang Wenyi Wang Dahua Shou Fei Lu Enling Hu Kun Yu Songmin Shang Ruiqi Xie | 2022 | Research2022，，4： | 0 |
| 13 | Determination of lisinopril using anion exchange chromatography with integrated pulsed amperometric detection显示文摘为在阴离子交换层析(原子能委员会) 的 lisinopril 的直接察觉的一个快速、实际的方法与综合搏动的安培计的察觉(IPAD ) 被开发了。Dionex AS18 (250 公里? | Yu Xiu Liu Dan Shou Mei Lan Chen Zhi Dong Chen Pei Min Zhang Yan Zhu | 2012 | Chinese Chemical Letters2012，23，3： | 0 |
| 14 | Chromatin and DNA chain fragmentation studies on apoptosis in immune cells induced by ^(235)U and radioprotection of IL-2 or IL-6显示文摘ChromatinandDNAchainfragmentationstudiesonapoptosisinimmunecelsinducedby235UandradioprotectionofIL2orIL6ZhuShouPeng,Zhang... | Zhu Shou Peng, Zhang Lan Sheng and Fu Qiang ( Suzhou Medical College, Suzhou 215007 ) | 1998 | Nuclear Science and Techniques1998，9，1： | 0 |
| 15 | A Novel Diagnostic and Therapeutic Strategy for Cancer Patients by Integrating Chinese Medicine Syndrome Differentiation and Precision Medicine显示文摘Applying Chinese medicine(CM) is an important strategy for malignant tumor treatment in China. One of the significant characteristics of CM is to treat diseases based on syndrome differentiation. For Western medicine, it is of important clinical significance to formulate guidelines for the diagnosis and treatment of cancer patients based on the characteristics of disease differentiation. In Chinese clinical practice, the combination of disease differentiation and syndrome differentiation is an important feature for cancer treatment in the past. Currently, molecular profiling and genomic analysis-based precision medicine optimizes the anticancer drug design and holds the greatest success in treating cancer patients. Therefore, we want to know which populations of cancer patients can benefit more from CM treatment if the theory of precision medicine is applied to CM clinical practice. So, we developed a novel diagnostic and therapeutic strategy 'disease-syndrome differentiation-genomic profilingprescriptions' for cancer patients by CM syndrome differentiation and precision medicine. As a result, this strategy has greatly enhanced the anti-tumor efficacy of CM and improved clinical outcomes for cancer patients with some gene mutations. Our idea will hopefully establish a novel approach for the inheritance and innovation of CM. | YU Shu-xian LIANG Zi-mao WU Qi-biao SHOU Lan HUANG Xing-xing ZHU Qian-ru XIE Han MEI Ru-yi ZHANG Ruo-nan ZHAI Xiang-yang XIE Tian SUI Xin-bing | 2022 | Chinese Journal of Integrative Medicine2022，28，10： | 0 |
| 16 | Determination of catecholamines by ion chromatography coupled to acidic potassium permanganate chemiluminescence detection显示文摘察觉在这份报纸被描述的为在由有化合光(CL ) 的离子层析(IC ) 的人的尿的 catecholamines 的决心的一个简单、快、敏感、高度选择、 eco 友好的分析方法。用没有是的任何器官的添加剂的 12 mmol/L H2SO4, eluent,包括肾上腺素(EP ) 的三 catecholamines,新肾上素(NE ) 和多巴胺(DA ) 是在阳离子交换列上分开的井。CL 察觉作为 enhancer 面对甲醛与酸的钾高锰酸盐基于 analytes 的反应。在 eluent 的甲醇和 acetonitrile 的缺席使建议方法更敏感、 eco 友好。在最佳的条件下面,建议方法的线性范围在 0.020.5 g/mL 的范围。察觉(LOD ) 的限制在 0.6 和 5.1 g/L 的范围。为 0.1 g/mL 的相对标准差(RSD ) 混合了标准答案在 0.81.9% 的范围(n = 11 ) 。方法成功地在人的尿被用于 catecholamines 的决心。优秀刺的恢复被完成因为 catecholamines 从 91.2% ~ 112.7%。 | Hong Wei Wu Mei Lan Chen Dan Shou Yan Zhu | 2012 | Chinese Chemical Letters2012，23，7： | 0 |
| 17 | A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier显示文摘In August 2021,three students with diarrhea from the same school visited a local hospital in the S district of Beijing.An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together.Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers;however,the latter also carried Campylobacter coli.Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students,and the asymptomatic food handler may have been the source of the infection.Routine inspection and surveillance for Campylobacter is needed for the food producing staff,particularly those cooking in the cafeteria in schools or other public food services. | YAN Ai Xia ZHOU Gui Lan GAO Peng KANG Ying LI Shou Fei WANG Yuan Yuan WANG Feng Shuang WANG Hai Rui LI Ying ZHANG Mao Jun | 2023 | Biomedical and Environmental Sciences2023，36，8： | 0 |
| 18 | Super-biderivations and Post-Lie Superalgebras on Some Lie Superalgebras显示文摘In this paper,all symmetric super-biderivations of some Lie superalgebras are determined.As an application,commutative post-Lie super algebra structures on these Lie super algebras are also obtained. | Munayim Dilxat Shou Lan Gao Dong Liu | 2023 | Acta Mathematica Sinica,English Series2023，39，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员