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| 1 | Effect of kidney-reinforcing,blood-activating and stasis-removing recipes on adhesion molecule expression of bone marrow mesenchymal stem cells from chronic aplastic anemia patients显示文摘OBJECTIVE:To explore the effect of kidney-reinforcing,blood-activating and stasis-removing recipes on adhesion molecule expression of bone marrow mesenchymal stem cells(MSCs) from patients with chronic aplastic anemia(CAA).METHODS:We used threeTraditional Chinese Medicine recipes,namely a kidney-reinforcing recipe(KRR),blood-activating and stasis-removing recipe(BASRR),and kidney-reinforcing,blood-activating and stasis-removing recipe(KRBASRR),and a normal saline control to prepare herbal medicine serum in Sprague Dawley rats.Thirty CAA patients were enrolled in the experimental group,including 17 kidney-Yang deficient patients and 13 kidney-Yin deficient patients.Ten healthy individuals were included in the control group.MSCs were isolated from bone marrow samples,and the cell density was observed to measure their proliferation ability by microscopy on days 2,7,and 14 after isolation.In addition,the expression of adhesion molecules of bone marrow MSCs(CD106,CD49d,CD31 and CD44) were detected by flow cytometry after 48 h of treatment with the four different herbal medicine serums.RESULTS:The proliferation of MSCs from kidney-Yang deficient and kidney-Yin deficient patients was weaker than that of MSCs from the control group.The expression of all adhesion molecules of bone marrow MSCs from CAA patients was obviously lower than that in the control group(P< 0.01).The expression of CD49d and CD31 in MSCs from patients with a kidney-Yin deficiency was lower than in those with a kidney-yang deficiency(P< 0.05 and P<0.01,respectively).For kidney-Yang deficient patients,CD31 expression in the KRBASRR group was significantly higher than that in the BASRR group(P<0.01),while CD44 in the KRBASRR group was significantly higher than that in both KRR and BASRR groups(P<0.01).For kidney-Yin deficient patients,CD106 and CD49d expression in the KRBASRR group was obviously higher than that in the KRR group(P<0.05),while CD31 and CD44 expression in the KRBASRR group was significantly higher than that in both KRR and BASRR groups(P< 0.05 and P<0.01,respectively).CONCLUSION:The bone marrow microenvironment in CAA patients is abnormal.The effect of KRBASRR may be better than that of KRR and BASRR for kidney-Yang deficient and kidney-Yin deficient patients by improving the expression levels of MSC adhesion molecules. | Baodong Ye Dan Chen Dijiong Wu Xiangping Wu Xiang Zhang Yuhong Zhou Yiping Shen Keding Shao Qinhong Yu | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 12 |
| 2 | Efficacy and safety of icotinib in Chinese patients with advanced non-small cell lung cancer after failure of chemotherapy显示文摘 | Shao Lan Zhang Beibei He Chunxiao Lin Baochai Song Zhengbo Lou Guangyuan Yu Xinmin Zhang Yiping | 2014 | Chinese Medical Journal2014，，2： | 12 |
| 3 | High-Sensitivity Temperature Sensor Based on Polarization Maintaining Fiber Sagnac Loop显示文摘A high-sensitivity all-fiber temperature sensor based on a Sagnac interferometer is demonstrated by splicing a section of polarization maintaining fiber(PMF)between two sections of standard single mode fibers(SMFs).In this sensor,the SMF-PMF-SMF structure in the Sagnac loop is bent into a circle to enhance the sensitivity.The length and curvature of the PMF in the loop are investigated and can be optimized to further increase the temperature sensitivity of the sensor. Results show that the radius of the circle has an important effect upon temperature sensitivity due to the bend-induced birefringence variation of the PMF.The SMF-PMF-SMF structure bent into a circle with a radius of 30mm exhibits a high-sensitivity temperature of 1.73nm/℃.The sensor is provided with the advantages of easy fabrication,low-insertion loss,and high sensitivity,which may find potential applications in the field of high precision temperature measurement. | Laipeng SHAO Junhui HU Hanglin LU Jing DU Tianyin WU Yiping WANG | 2019 | Photonic Sensors2019，9，1： | 10 |
| 4 | Efficacy and advantages of modified Traditional Chinese Medicine treatments based on'kidney reinforcing'for chronic aplastic ane-mia:a randomized controlled clinical trial显示文摘OBJECTIVE:To compare the efficacy of modified treatments based on 'kidney reinforcing' in the management of chronic aplastic anemia(CAA),and explore their advantages and specialties.METHODS:One hundred and eleven patients with CAA were randomly divided into three groups:kidney reinforcing alone(KA),'kidney reinforcing and Qi tonifying'(KQ),and 'kidney reinforcing and blood circulation invigorating'(KC).Normal and positive control groups were also formed.All patients were treated for 6 months(two courses).Hemograms,Traditional Chinese Medicine(TCM) syndrome scores,and therapeutic effects were assessed,and changes in T-lymphocyte subsets,regulatory T cells and cytokines were detected.RESULTS:The KQ and KC groups had lower TCM syndrome scores than the positive control group after 6 months(P < 0.05).The KQ group had a higher overall efficacy than the positive control group after 3 months(P < 0.05),while platelet counts increased in the KC group after 6 months(P < 0.05).CD3+ T-lymphocyte ratios decreased only in the KQ group,while CD3 + CD4 + CD8-Tlymphocytes increased only in the KC group after 6 months(P <0.05).Levels of interferon-γ,tumor necrosis fac-tor-α,interleukin(IL)-2 and IL-6 decreased and levels of IL-4 and IL-10 increased in all treated groups after 6 months.Levels of IL-6 in the KQ and KC groups were lower than those in the positive control group(P < 0.05).CONCLUSION:Treatments based on kidney reinforcing have a rebalancing effect on cytotoxic and T helper cells,and regulate expression of interferon-γ,IL-2,IL-6 and IL-4.KQ may be more effective in treating CAA,and KC may have an advantage in platelet recovery. | Wu Dijiong Shen Yiping Ye Baodong Fang Bingmu Lin Shengyun Chen Zhilu Jiang Huifang Feng Changwei He Lüyuan Gao Yanting Liu Yonglin Liu Yonghua Zhu Jiajia Wu Liqiang Shao Keding Zhou Yuhong | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 6 |
| 5 | Experimental study on water permittivity of woven polypropylene geotextile under tension显示文摘 | Yiping Zhang Weichao Liu Weiyun Shao Yan Yang | 2013 | Geotextiles and Geomembranes2013，，： | 3 |
| 6 | Construction of the Continental Asia in Phanerozoic:A Review显示文摘This is a review of the formation and tectonic evolution of the continental Asia in Phanerozoic.The continental Asia has formed on the bases of some pre-Cambrian cratons,such as the Siberia,India,Arabia,North China,Tarim,South China,and Indochina,through multi-stage plate convergence and collisional collages in Phanerozoic.The north-central Asia had experienced the expansion and subduction of the Paleo-Asian Ocean(PAO)in the early Paleozoic and the closure of the PAO in the late Paleozoic and early Mesozoic,forming the PAO regime and Central Asian orogenic belt(CAOB).In the core of the CAOB,the Mongol-Okhotsk Ocean(MOO)opened with limited expansion in the Early Permian and finally closed in the Late Jurassic–Early Cretaceous.The south-central Asia had experienced mainly multi-stage oceanic opening,subduction and collision evolution in the Tethys Ocean,forming the Tethys regime and Himalaya-Tibetan orogenic belt.In eastern Asia,the plate subduction and continental margin orogeny on western margin of the Pacific Ocean,forms the West Pacific regime and West Pacific orogenic belt.The PAO,Tethys,and West Pacific regimes,together with Precambrian cratons among or surrounding them,made up the major tectonic and dynamic systems of the continental Asia in Phanerozoic.Major tectonic events,such as the Early Paleozoic Qilian,Uralian,and Dunhuang orogeneses,the late Paleozoic East Junggar,Tianshan and West Junggar orogeneses,the Middle to Late Permian Ailaoshan orogeny and NorthSouth Lhasa collision,the early Mesozoic Indochina-South China and North-South China collisions,the late Mesozoic Mongolia-Okhotsk orogeny,Lhasa-Qiangtang collision,and intra-continental Yanshanian orogeny,and the Cenozoic IndoAsian,Arab-Asian,and West Pacific margin collisions,constrained the formation and evolution of the continental Asia.The complex dynamic systems have left large number of deformation features,such as large-scale strike-slip faults,thrustfold systems and extensional detachments on the continental Asia.Based on past tectonics,a future supercontinent,the Ameurasia,is prospected for the development of the Asia in ca.250 Myr. | CHEN Xuanhua DONG Shuwen SHI Wei DING Weicui ZHANG Yiping LI Bing SHAO Zhaogang WANG Ye | 2022 | Acta Geologica Sinica(English Edition)2022，96，1： | 3 |
| 7 | Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry显示文摘 | Yiping Ren Yu Zhang Shuangliang Shao Zengxuan Cai Liang Feng Hongfeng Pan Zhigang Wang | 2006 | Journal of Chromatography A2006，，1： | 3 |
| 8 | Faceted Kurdjumov-Sachs interface-induced slip continuity in the eutectic high-entropy alloy,AlCoCrFeNi_(2.1)显示文摘Recently,the eutectic high-entropy alloy(EHEA),AlCoCrFeNi_(2.1),can reach a good balance of strength and ductility.The dual-phase alloy exhibits a eutectic lamellar microstructure with large numbers of interfaces.However,the role of the interfaces in plastic deformation have not been revealed deeply.In the present work,the orientation relationship(OR)of the interfaces has been clarified as the Kurdjumov-Sachs(KS)interfaces presenting〈111〉_(B2) 〈110〉_(FCC)and {110} _(B2){111}_(FCC) independent of their morphologies.There exist three kinds of interfaces in the EHEA,namely,The dominating interface and the secondary interface are both non-slip planes and atomistic-scale faceted,facilitating the nucleation and slip transmission of the dislocations.The formation mechanism of the preferred interfaces is revealed using the atomistic geometrical analysis according to the criteria of the low interfacial energy based on the coincidence-site lattice(CSL)theory.In particular,the ductility of the dual-phase alloy originates from the KS interface-induced slip continuity across interfaces,which provides a high slip-transfer geometric factor.Moreover,the strengthening effect can be attributed to the interface resistance for the dislocation transmission due to the mismatches of the moduli and lattice parameters at the interfaces. | Ting Xiong Wenfan Yang Shijian Zheng Zhaorui Liu Yiping Lu Ruifeng Zhang Yangtao Zhou Xiaohong Shao Bo Zhang Jun Wang Fuxing Yin Peter K.Liaw Xiuliang Ma | 2021 | Journal of Materials Science & Technology2021，，6： | 2 |
| 9 | Evaluation of HAMAMATSU R5900 Series PMTs for Readout of High-Resolution Scintillator Arrays显示文摘 | Shao Yiping Silverman RW | 2000 | Nucl Instrum Methods in Phys Res2000，454，： | 1 |
| 10 | Sim- uhaneous determination of multi - component mycotoxin contaminants in foods and feeds by ultraperformance liquid chromatography tandem mass spectrometry 显示文摘 | REN Yiping ZHANG Yu SHAO Shuangliang | 2007 | J Chroma- togr A2007，1143，12： | 1 |
| 11 | Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry显示文摘 | Yiping Ren Yu Zhang Shuangliang Shao Zengxuan Cai Liang Feng Hongfeng Pan Zhigang Wang | 2006 | Journal of Chromatography A2006，，1： | 1 |
| 12 | SPECT mouse imaging on a hybrid micro-PET/SPECT system 显示文摘 | MA Tianyu SHAO Yiping Sajjad Munawaar | 2008 | J Nucl Med2008，49，1： | 1 |
| 13 | Evaluation of Hamamatsu R5900 series PMTs for readout of high-resolution scintillator arrays显示文摘 | | 2000 | Nucl Instrum Methods2000，454，： | 1 |
| 14 | Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry显示文摘 | Yiping Ren Yu Zhang Shuangliang Shao Zengxuan Cai Liang Feng Hongfeng Pan Zhigang Wang | 2006 | Journal of Chromatography A2006，，1： | 1 |
| 15 | Derivation of system matrix from simulation data for an animal SPECT with slitslat collimator显示文摘 | YAO Rutao MA Tianyu SHAO Yiping | 2009 | IEEE Trans Nucl Sci2009，56，5： | 1 |
| 16 | Evaluation of Hamamatsu R5900 Series PMTs for Readout of High-resolution Scintillator Arrays 显示文摘 | Yiping Shao | 2000 | Nucl Instrum Methods2000，454，： | 1 |
| 17 | Imaging performance evaluation in depth-of-interaction PET with a new method of sinogram generation:A Monte Carlo simulation study显示文摘In conventional PET systems,the parallax error degrades image resolution and causes image distortion.To remedy this,a PET ring diameter has to be much larger than the required size of field of view(FOV),and therefore the cost goes up.Measurement of depth-of-interaction(DOI)information is effective to reduce the parallax error and improve the image quality.This study is aimed at developing a practical method to incorporate DOI information in PET sinogram generation and image reconstruction processes and evaluate its efficacy through Monte Carlo simulation.An animal PET system with 30-mm long LSO crystals and 2-mm DOI measurement accuracy was simulated and list-mode PET data were collected.A sinogram generation method was proposed to bin each coincidence event to the correct LOR location according to both incident crystal indices and DOI positions of the two annihilation photons.The sinograms were reconstructed with an iterative OSMAPEM(ordered subset maximum a posteriori expectation maximization)algorithm.Two phantoms(a rod source phantom and a Derenzo phantom)were simulated,and the benefits of DOI were investigated in terms of reconstructed source diameter(FWHM)and source positioning accuracy.The results demonstrate that the proposed method works well to incorporate DOI information in data processing,which not only overcomes the image distortion problem but also significantly improves image resolution and resolution uniformity and results in satisfactory image quality. | XIA Yan MA Tianyu LIU Yaqiang SUN Xishan WANG Shi SHAO Yiping | 2011 | Nuclear Science and Techniques2011，22，3： | 1 |
| 18 | MicroPET:A high resolution PET scanner for imaging small animals显示文摘 | Cherry SR Shao Yiping Silverman RW | 1997 | IEEE Trans on Nucl Sci1997，44，3： | 1 |
| 19 | Performance evaluation of microPET:A high-resolution lutetium oxyorthosilicate PET scanner for animal imaging显示文摘 | Chatziioannou AF Cherry SR Shao Yiping | 1999 | J Nucl Med1999，40，7： | 1 |
| 20 | Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra performance liquid chromatography tandem mass spectrometry显示文摘 | REN Yiping ZHANG Yu SHAO Shuangliang | 2007 | Journal of Chromatography A2007，1143，： | 1 |
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