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1Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing显示文摘COVID-19,caused by SARS-CoV-2[1,2],has been contained in China through stringent non-pharmaceutical interventions.Border control and quarantine have effectively prevented the virus from being spread by infected travellers,but the risk of resurgence caused by other routes of introduction and transmission remains unclear,and current strategies to prevent resurgence could be flawed.Since July,SARS-CoV-2 RNA contaminations in frozen food imported from countries with ongoing epidemics have been reported in nine provinces in China[3,4].However,there is no robust evidence of COVID-19 outbreaks initiated by environmentto-human transmission.Here we add to evidence of such transmission by investigating the recent COVID-19 resurgence in Beijing.Xinghuo Pang Lili Ren Shuangsheng Wu Wentai Ma Jian Yang Lin Di Jie Li Yan Xiao Lu Kang Shichang Du Jing Du Jing Wang Gang Li Shuguang Zhai Lijuan Chen Wenxiong Zhou Shengjie Lai Lei Gao Yang Pan Quanyi Wang Mingkun Li Jianbin Wang Yanyi Huang Jianwei Wang COVID-19 Field Response Group COVID-19 Laboratory Testing Group 2020National Science Review2020,7,12:51
2Extreme drought changes in Southwest China from 1960 to 2009显示文摘从 1960 ~ 2009 在西南中国基于温度的每日的数据和 108 个气象学的车站的降水,我们计算每月、每年的表面潮湿的索引,以及极端干旱频率。根据数据,极端干旱频率在的时间、空间的特征内部年度,内部十,夏天季风时期和冬季季风时期被分析。结果如下被显示。(1 ) 一般来说,西南的四川盆,南部的 Hengduan 山, Guangxi 的南部的海岸和北贵州是极端干旱频率显著地在过去的 50 年里增加了的区域。至于十的变化,从 1960 年代,到 1980 年代,极端干旱频率介绍了一个减少的趋势,当 1990 年代是最湿的十年,整个区域正在变得湿时。在 2000 年代,极端干旱频率快速升起,但是地区性的差别还原剂。(2 ) 在夏天季风时期期间,干旱频率正在成长的极端,通常在四川盆附近发生在高山,最在云南 Guangxi 和塑造扫帚的山分开。高度在极端干旱频率上有影响,是不同的;在冬季季风时期期间,区域是相对湿的,极端干旱频率正在减少。(3 ) 在夏天季风时期期间,突然的变化在 2003 被观察,而突然的变化在冬季季风时期期间在 1989。年度极端干旱频率变化在夏天季风和冬季季风时期期间是突然的变化的重叠。年度极端干旱频率的离开顺序颤动是 quasi-5 年和 quasi-12 年。ZHANG Mingjun HE Jinyun WANG Baolong WANG Shengjie LI Shanshan LIU Wenli MA Xuening 2013Journal of Geographical Sciences2013,23,1:43
3Polymorphisms in PPARD,PPARG and APM1 associated with four types of Traditional Chinese Medicine constitutions显示文摘Based on the theory of constitution of Traditional Chinese Medicine (TCM), the human population is divided into nine constitutions including one balanced constitution (Normality) and eight unbalanced constitutions (Yang-deficiency, Yin-deficiency, Phlegm-wetness, Qi-deficiency, Wetness-heat, Blood stasis, Depressed constitution, and Inherited special constitution). Different constitutions have specific metabolic features and different susceptibility to certain diseases. However, whether a genetic basis accounts for such constitution classifica-tion is yet to be determined. Here we performed a genetic study to assess the association between genetic variations of metabolic genes in-cluding PPARD, PPARG and APM1 and the constitutions. A total of 233 individuals of the Han population in China were classified into four groups, Normality, Yang-deficiency, Yin-deficiency and Phlegm-wetness with whom 23 single nucleotide polymorphisms (SNPs) in the three genes were genotyped using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Biased distri-bution of PPARD rs2267669 and rs2076167, APM1 rs7627128 and rs1063539 in Yang-deficiency, PPARG Pro12Ala in Yin-deficiency and PPARD rs2076167, APM1 rs266729 and rs7627128 in Phlegm-wetness were observed. The frequencies of Haplotype13 (Hap13) of PPARG in Yin-deficiency, Hap25 of APM1 in Yang-deficiency and Hap2 of PPARD and Hap14 of PPARG in Phlegm-wetness, were significantly different from those in Normality, suggesting those might be group-associated haplotypes. These results suggested that single SNP and hap-lotypes of PPARD, PPARG and APM1 may underlie the genetic basis of the constitutions classified in TCM.Yanrui Wu Yina Cun Jing Dong Jingru Shao Shengjun Luo Shengjie Nie Haijing Yu Bingrong Zheng Qi Wang Chunjie Xiao 2010Journal of Genetics and Genomics2010,37,6:36
4Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders:executive summary and 2019 update of clinical management of stroke rehabilitation显示文摘Stroke is the third leading cause of long-term disability.Effective stroke rehabilitation should be provided to patients with a moderate or severe stroke so as to achieve functional recovery.Also,stroke rehabilitation is moving towards more intense therapy models that incorporate technologies such as robotics and computer games.Evidence-based guidelines are useful for promoting the best possible clinical practices.This guideline summarises the modes of stroke rehabilitation in China-three-stage rehabilitation network,rehabilitation of stroke dysfunction,training for activities of daily living,stroke complications and rehabilitation care.The aim of this guideline was to provide a synopsis of best clinical practices in the stroke rehabilitation of adult patients in China.Tong Zhang Jun Zhao Xueping Li Yulong Bai Baojun Wang Yun Qu Bingjie Li Shengjie Zhao Chinese Stroke Association Stroke Council Guideline Writing Committee 2020Stroke & Vascular Neurology2020,5,3:38
5Glacier area variation and climate change in the Chinese Tianshan Mountains since 1960显示文摘基于自从 1960,在中国 Tianshan 山测量的冰河区域变化的统计,到气候变化的冰河区域变化的反应系统地被讨论。作为结果,冰河的全部的区域被 11.5% 在过去的 50 年里减少了,它根据中国(GIC ) 的冰河库存分开的 10 排水盆的冰河区域变化是一个加权的百分比。在中国 Tianshan 山的冰河的区域变化(APAC ) 的年度百分比在学习时期的标准化以后是 0.31% 。APAC 为不同排水盆广泛地变化,但是冰河通常处于快速的撤退的一个国家。根据在中国 Tianshan 山的 14 个气象学的车站,温度和降水以 0.34 整湲椠 ? 潮 ?湵晩牯 m 的率从 1960 ~ 2009WANG Shengjie ZHANG Mingjun LI Zhongqin WANG Feiteng LI Huilin LI Yaju HUANG Xiaoyan 2011Journal of Geographical Sciences2011,21,2:31
6Wx^lv、the Ancestral Allele of Rice Waxy Gene显示文摘In rice grains,the Waxy (Wx) gene is responsible for the synthesis of amylose,the most important determinant for eating and cooking quality.The effects of several Wx alleles on amylose content and the taste of cooked rice have been elucidated.However,the relationship between artificial selection and the evolution of various Wx alleles as well as their distribution remain unclear.Here we report the identification of an ancestral allele,Wx^lv,which dramatically affects the mouthfeel of rice grains by modulating the size of amylose molecules.We demonstrated that WF originated directly from wild rice,and the three major Wx alleles in cultivated rice (Wx^b,Wx^a,and Wx^in) differentiated after the substitution of one base pair at the functional sites.These data indicate that the Wx^lv allele played an important role in artificial selection and domestication.The findings also shed light on the evolution of various Wx alleles,which have greatly contributed to improving the eating and cooking quality of rice.Changquan Zhang Jihui Zhu Shengjie Chen Xiaolei Fan Qianfeng Li Yan Lu Min Wang Hengxiu Yu Chuandeng Yi Shuzhu Tang Minghong Gu Qiaoquan Liu 2019Molecular Plant2019,12,8:22
7New insights into gibberellin signaling in regulating flowering in Arabidopsis显示文摘In angiosperms,floral transition is a key developmental transition from the vegetative to reproductive growth,and requires precise regulation to maximize the reproductive success.A complex regulatory network governs this transition through integrating flowering pathways in response to multiple exogenous and endogenous cues.Phytohormones are essential for proper plant developmental regulation and have been extensively studied for their involvement in the floral transition.Among various phytohormones,gibberellin(GA)plays a major role in affecting flowering in the model plant Arabidopsis thaliana.The GA pathway interact with other flowering genetic pathways and phytohormone signaling pathways through either DELLA proteins or mediating GA homeostasis.In this review,we summarize the recent advances in understanding the mechanisms of DELLA-mediated GA pathway in flowering time control in Arabidopsis,and discuss its possible link with other phytohormone pathways during the floral transition.Shengjie Bao Changmei Hua Lisha Shen Hao Yu 2020Journal of Integrative Plant Biology2020,62,1:21
85-Methylcytosine RNA Methylation in Arabidopsis Thaliana显示文摘5-Methylcytosine (m 5 C ) 是描绘得好的 DNA 修正,并且主要也在初核质和优核质在丰富的非编码的 RNA 被报导。然而,分发和 m 5 在植物 mRNAs 的 C 仍然保持大部分未知。这里,我们报导 RNA m 5 在由使用 m 5 C RNA immunoprecipitation 由一条深定序的途径列在后面(m 5 C-RIP-seq ) 。LC-MS/MS 和点污点分析揭示 m 5 在各种各样的纸巾并且在不同发展阶段的 C mRNA 修正。m 5 C-RIP-seq 分析识别了 6045 m 5 在 4465 的 C 山峰在年轻幼苗表示了基因。我们发现那 m 5 C 在编码序列,二座山峰在开始 codons 以后并且在站 codons 前立即定位了被充实,并且随低翻译与 mRNAs 被联系活动。我们进一步表明了那 RNA (cytosine-5 )-methyltransferase,tRNA 特定的 methyltransferase 4B (TRM4B ) ,展览 m 5 C RNA methyltransferase 活动。在 TRM4B 的变化在根开发和减少的 m 5 C 山峰。TRM4B 影响涉及根开发的基因的抄本层次,它断然与他们的 mRNA 稳定性和 m 5 C 层次。我们的结果建议那 m 5 在 mRNA 的 C 是新 epitranscriptome 标记 inArabidopsis,并且这修正的那条规定是基因的不可分的部分规章的网络位于 \O 下面植物开发。Xuean Cui Zhe Liang Lisha Shen Qian Zhang Shengjie Bao Yuke Geng Bin Zhang Vonny Leo Leah A. Vardy Tiegang Lu Xiaofeng Gu Hao Yu 2017Molecular Plant2017,10,11:19
9A rare Waxy allele coordinately improves rice eating and cooking quality and grain transparency显示文摘In rice(Oryza sativa), amylose content(AC) is the major factor that determines eating and cooking quality(ECQ). The diversity in AC is largely attributed to natural allelic variation at the Waxy(Wx)locus. Here we identified a rare Wx allele, Wx^(mw) ,which combines a favorable AC, improved ECQ and grain transparency. Based on a phylogenetic analysis of Wx genomic sequences from 370 rice accessions, we speculated that Wx^(mw) may have derived from recombination between two important natural Wx alleles, Wx^(in) and Wx^(b). We validated the effects of Wx^(mw) on rice grain quality using both transgenic lines and near-isogenic lines(NILs). When introgressed into the japonica Nipponbare(NIP) background, Wx^(mw) resulted in a moderate AC that was intermediate between that of NILs carrying the Wx^(b)allele and NILs with the Wx^(mp) allele. Notably, mature grains of NILs fixed for Wx^(mw) had an improved transparent endosperm relative to soft rice. Further, we introduced Wx^(mw) into a high-yielding japonica cultivar via molecular marker-assisted selection: the introgressed lines exhibited clear improvements in ECQ and endosperm transparency. Our results suggest that Wx^(mw) is a promising allele to improve grain quality, especially ECQ and grain transparency of high-yielding japonica cultivars, in rice breeding programs.Changquan Zhang Yong Yang Shengjie Chen Xueju Liu Jihui Zhu Lihui Zhou Yan Lu Qianfeng Li Xiaolei Fan Shuzhu Tang Minghong Gu Qiaoquan Liu 2021Journal of Integrative Plant Biology2021,63,5:18
10Glacier area shrinkage in China and its climatic background during the past half century显示文摘在遥感监视的中国的典型区域基于冰河区域变化记录,吗象从 139 的空气温度和 降水的气象学的数据一样驻扎并且 0 ??????????????????????????吠慭吗??ZHANG Mingjun WANG Shengjie LI Zhongqin WANG Feiteng 2012Journal of Geographical Sciences2012,22,1:14
11Changes in temperature extremes in the Yangtze River Basin, 1962-2011显示文摘Based on daily maximum and minimum temperature observed by the China Meteorological Administration at 115 meteorological stations in the Yangtze River Basin from 1962 to 2011,the methods of linear regression,principal component analysis and correlation analysis are employed to investigate the temporal variability and spatial distribution of temperature extremes.Sixteen indices of extreme temperature are selected.The results are as follows:(1) The occurrence of cold days,cold nights,ice days,frost days and cold spell duration indicator has significantly decreased by –0.84,–2.78,–0.48,–3.29 and –0.67 days per decade,respectively.While the occurrence of warm days,warm nights,summer days,tropical nights,warm spell duration indicator and growing season length shows statistically significant increasing trends at rates of 2.24,2.86,2.93,1.80,0.83 and 2.30 days per decade,respectively.The tendency rate of the coldest day,coldest night,warmest day,warmest night and diurnal temperature range is 0.33,0.47,0.16,0.19 and –0.07℃ per decade,respectively.(2) The magnitudes of changes in cold indices(cold nights,coldest day and coldest night) are obviously greater than those of warm indices(warm nights,warmest day and warmest night).The change ranges of night indices(warm nights and cold nights) are larger than those of day indices(warm days and cold days),which indicates that the change of day and night temperature is asymmetrical.(3) Spatially,the regionally averaged values of cold indices in the upper reaches of the Yangtze River Basin are larger than those in the middle and lower reaches.However,the regionally averaged values of most warm indices(except warm spell duration indicator) and growing season length in the middle and lower reaches are larger than those in the upper reaches.(4) The extreme temperature indices are well correlated with each other except diurnal temperature range.WANG Qiong ZHANG Mingjun WANG Shengjie MA Qian SUN Meiping 2014Journal of Geographical Sciences2014,24,1:14
12Assessment of diurnal variation of summer precipitation over the Qilian Mountains based on an hourly merged dataset from 2008 to 2014显示文摘调查日报在在向东北西藏的高原的 Qilian 山的夏天降水的变化,时时,为这个区域的降水数量在 0.1 点用一个时时合并的降水产品在 2008-2014 的夏天期间被分析 ? 湵慦潶慲汢? 諟D禎澞?汣浩瑡 ? 档湡敧椠??LIU Xuemei ZHANG Mingjun WANG Shengjie WANG Jie ZHAO Peipei ZHOU Panpan 2017Journal of Geographical Sciences2017,27,3:14
13The microphysics of ice accretion on wires:Observations and simulations显示文摘The weather system, meteorological conditions, and microphysics of cloud, fog, and rain droplets are studied during the formation, growth, maintenance, and shedding periods of ice accretion on wires in Enshi, Hubei Province in China using 2008/2009 and 2009/2010 winter observations. The comprehensive observations include data of visibility, microphysics of fog and rain droplets, and ice thickness, as well as data from an automated weather station and other routinely recorded meteorological data. The results show that icing occurred during the passage of a cold front, with a high-pressure system and a cold temperature trough at 850 hPa, and a southeasterly at 500 hPa that provided abundant moisture. Ice formation usually started in the evening or early morning, and ice shed around noon the following day when the temperature was-1°C to 0°C. The averaged liquid water content of the fog droplet was distinctly greater during the growth period than during the other three periods, and there was precipitation during the growth period in each case of ice accretion. The growth rate of the ice thickness was clearly correlated with the liquid water content, with a correlation coefficient of 0.62. Simulations using empirical equations were carried out, and the simulated ice thickness agreed with observations fairly well.NIU ShengJie ZHOU Yue JIA Ran YANG Jun LUE JingJing KE YiMing YANG ZhiBiao 2012Science China Earth Sciences2012,55,3:12
14MicroTom Metabolic Network: Rewiring Tomato Metabolic Regulatory Network throughout the Growth Cycle显示文摘Tomato(Solanum lycopersicum)is a major horticultural crop worldwide and has emerged as a preeminent model for metabolic research.Although many research efforts have focused on the analysis of metabolite differences between varieties and species,the dynamics of metabolic changes during the tomato growth cycle and the regulatory networks that underlie these changes are poorly understood.In this study,we integrated high-resolution spatio-temporal metabolome and transcriptome data to systematically explore the metabolic landscape across 20 major tomato tissues and growth stages.In the resulting MicroTom Metabolic Network,the 540 detected metabolites and their co-expressed genes could be divided into 10 distinct clusters based on their biological functions.Using this dataset,we constructed a global map of the major metabolic changes that occur throughout the tomato growth cycle and dissected the underlying regulatory network.In addition to verifying previously well-established regulatory networks for important metabolites,we identified novel transcription factors that regulate the biosynthesis of important secondary metabolites such as steroidal glycoalkaloids and flavonoids.Our findings provide insights into spatiotemporal changes in tomato metabolism and generate a valuable resource for the study of metabolic regulatory processes in model plants.Yan Li Yang Chen Lu Zhou Shengjie You Heng Deng Ya Chen Saleh Alseekh Yong Yuan Rao Fu Zixin Zhang Dan Su Alisdair R.Fernie Mondher Bouzayen Tao Ma Mingchun Liu Yang Zhang 2020Molecular Plant2020,13,8:10
15Changes in daily extreme precipitation events in South China from 1961 to 2011显示文摘从 0.5 摩敤基于每日的降水吗??REN Zhengguo ZHANG Mingjun WANG Shengjie QIANG Fang ZHU Xiaofan DONG Lei 2015Journal of Geographical Sciences2015,25,1:10
16Changes in air temperature over China in response to the recent global warming hiatus显示文摘The 1998-2012 global wanning hiatus has aroused great public interest over the past several years.Based on the air temperature measurements from 622 meteorological stations in China,the temperature response to the global warming hiatus was analyzed at national and regional scales.We found that air temperature changed-0.221°C/10a during 1998-2012,which was lower than the long-term trend for 1960-1998 by 0.427°C/10a.Therefore,the warming hiatus in China was more pronounced than the global mean.Winter played a domi nant role in the nati on wide warming hiatus,con tributi ng 74.13%,while summer contributed the least among the four seasons.Furthermore,the warming hiatus was spatial heterogeneous across different climate conditions in China.Comparing the three geographic zones,the monsoon region of eastern China,arid region of northwestern China,and high frigid region of the Tibetan Plateau,there was significant cooling in eastern and northwestern China.In eastern China,which contributed 53.79%,the trend magnitudes were 0.896°C/10a in winter and 0.134°C/10a in summer.In the Tibeta n Plateau,air temperature in creased by 0.204°C/10a,indicating a lack of a significant warming hiatus.More broadly,the warming hiatus in China may have been associated with the negative phase of PDO and reduction in sunspot numbers and total solar radiation.Finally,although a warming hiatus occurred in China from 1998 to 2012,air temperature rapidly increased after 2012 and will likely to continuously warm in the next few years.DU Qinqin ZHANG Mingjun WANG Shengjie CHE Cunwei MA Rong MA Zhuanzhuan 2019Journal of Geographical Sciences2019,29,4:9
17RS analysis of glaciers change in the Heihe River Basin, Northwest China, during the recent decades显示文摘Heihe 河盆是在西北中国的第二最大的内陆河盆,它也是在干旱水文学,水资源和在冷区域的研究的另外的方面的一个热点。另外, Heihe 河盆有完全的风景,中等分水岭尺寸,和典型社会生态的环境问题。到目前为止,没有对整个河盆的冰河变化信息的详细评价。地志的地图数据, Landsat TM/ETM+ 遥感图象和数字举起建模的 1:50,000 数据在这研究被使用。通过综合计算机自动解释和视觉解释方法,面向对象的图象特征抽取方法被使用提取冰河轮廓信息。冰河变化数据从分析被导出,并且到气候的冰河变化和它的反应在时期 1956/19632007/2011 变化也被分析。结果显示出那:(1 ) 在时期 1956/19632007/2011, Heihe 河盆冰河有一个明显的撤退趋势,冰河的全部的区域从 361.69 km 减少了 < 啜 class= “ a-plus-plus ” > 2 到 231.17 km < 啜 class= “ a-plus-plus ” > 2 ;以 36.08% 的率缩小,与平均单个冰河区域减少 0.14 km < 啜 class= “ a-plus-plus ” > 2 ;冰河的全部的数字从 967 ~ 800 减少了。(2 ) 在这盆的冰河主要在 43004400 m, 44004500 m 和 45004600 m 的举起被散布;并且在冰河分发和冰河变化有重要地区性的差别。(3 ) 与另外的西方的山冰河相比,在 Heihe 河盆的冰河撤退有更高的率。(4 ) 六个气象学的车站的分析从 1960 ~ 2010 的年度平均温度和降水数据建议吝啬的年度温度显著地增加了,年度降水也显示出一个增加的趋势。冰河收缩是密切相关的,而且,温度升起,这被结束冰河融化由增加的降水由比冰河团供应大的升起的温度引起了到某程度。HUAI Baojuan LI Zhongqin WANG Shengjie SUN Meiping ZHOU Ping XlAO Yan 2014Journal of Geographical Sciences2014,24,6:9
18Stress-strain behavior of multi-phase high performance structural steel显示文摘A series of ferrite/bainite(F/B) multi-phase steels containing different volume fractions of ferrite were obtained.The effect of soft phase(ferrite) content on the work-hardening behavior of the steel was studied by the finite element simulation with V-BCC model and the modified Crussard-Jaoul(C-J) analysis.It is shown that the multi-phase steels have an excellent anti-deformation ability,such as higher stress ratio(R t1.5 /R t0.5),higher uniform elongation and lower yield to tensile strength ratio.For the F/B multi-phase steels,increasing the proportion of ferrite would help to increase the uniform elongation.However,introducing much more fraction of ferrite would not be helpful to improve the stress ratio of multi-phase steel.The ferrite plastic strain constrained by bainite would be beneficial to increasing the work hardening rate.The optimum proportion of ferrite will result both higher stress ratio and uniform elongation in multi-phase steel.NIE WenJin WANG XueMin WU ShengJie GUAN HaiLong SHANG ChengJia 2012Science China(Technological Sciences)2012,55,7:8
19Synergistic therapy of magnetism-responsive hydrogel for soft tissue injuries显示文摘Soft tissue injury is very common and associated with pain,tissue swelling and even malformation if not treated on time.Treating methods include cryotherapy,electrical therapy,ultrasound therapy and anti-inflammatory drug,but none of them is completely satisfying.In this work,for a better therapeutic effect,drug therapy and pulsed electromagnetic field(PEMF)therapy were combined.We constructed a drug delivery system using the tetra-PEG/agar hydrogel(PA).By incorporating Fe3O4 NPs into the hydrogel network,a magnetism-responsive property was achieved in the system.The cytotoxicity and in vivo study showed a good biocompatibility of the PA/Fe3O4 hydrogel.A magnetism-controlled release was attained by the incorporation of Fe3O4.Finally,in vivo study showed a better performance of the DS-loaded PA/Fe3O4 compared with the commercially available DS ointment regarding the recovery of the injured soft tissue.Therefore,this magnetism-responsive hydrogel may represent a promising alternative to treat soft tissue injury.Lining Zhang Xiuqin Zuo Shengjie Li Mi Sun Huimin Xie Kai Zhang Jikun Zhou Liyun Che Junxuan Ma Zishan Jia Fei Yang 2019Bioactive Materials2019,4,1:7
20Sedimentary sequence and environmental evolution in theeastern south Yellow Sea during the last deglaciation and the holocene显示文摘Northwest of Cheju Island in the eastern South Yellow Sea there is an arc patch of muddy deposit which coincides with an anticlokwise eddy and thus is referred to as muddy deposit of eddy. Two drilling wells, the YSDP 102 well and the YSDP 103 well, penetrated the muddy deposit and revelated the sedimentary sequence in the sea area during the last deglaciation and the Holocene. Based on shallow seismic profiles, sedimentary features and dating data, stratigraphic units formed in the eastern South Yellow Sea, documents the path, time and process of the earliest post-glacial transgression in the South Yellow Sea are presented, the formation of the Yellow Sea warm current and its control over the Yellow Sea sedimentation are discussed, and deals with the source of the muddy deposit is dealt with.Shaoquan Li Jian Liu Shengjie Wang Zigeng Yang 1998Chinese Science Bulletin1998,43,9:6
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