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| 1 | Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats显示文摘Clinical and animal studies have indicated that propofol has potential for abuse,but the specific neurobiological mechanism underlying propofol reward is not fully understood.The purpose of this study was to investigate the role of extracellular signal-regulated kinase(ERK) signal transduction pathways in the nucleus accumbens(NAc) in propofol self-administration.We tested the expression of p-ERK in the NAc following the maintenance of propofol self-administration in rats.We also assessed the effect of administration of SCH23390,an antagonist of the D1 dopamine receptor,on the expression of p-ERK in the NAc in propofol self-administering rats,and examined the effects of intra-NAc injection of U0126,an MEK inhibitor,on propofol reinforcement in rats.The results showed that the expression of p-ERK in the NAc increased significantly in rats maintained on propofol,and pre-treatment with SCH23390 inhibited the propofol selfadministration and diminished the expression of p-ERK in the NAc.Moreover,intra-NAc injection of U0126(4 μg/side) attenuated the propofol self-administration.The data suggest that ERK signal transduction pathways coupled with D1 dopamine receptors in the NAc may be involved in the maintenance of propofol self-administration and its rewarding effects. | Benfu Wang Xiaowei Yang Anna Sun Lanman Xu Sicong Wang Wenxuan Lin Miaojun Lai Huaqiang Zhu Wenhua Zhou Qingquan Lian | 2016 | Neuroscience Bulletin2016,32,6: | 12 |
| 2 | Self-powered macroscopic Brownian motion of spontaneously running liquid metal motors显示文摘We disclosed the interiorly driven macroscopic Brownian motion behavior of self-powered liquid metal motors. Such tiny motors in millimeter scale move randomly at a velocity magnitude of centimeters per second in aqueous alkaline solution, well resembling the classical Brownian motion. However, unlike the existing phenomena, where the particle motions were caused by collisions from the surrounding molecules, the current random liquid metal motions are internally enabled and self-powered,along with the colliding among neighboring motors, the substrate and the surrounding electrolyte molecules.Through uniformly dissolving only 1 %(mass percentage)Al into Ga In10, many tiny motors can be quickly fabricated and activated to take the Brownian-like random motions. Further, we introduced an experimental approach of using optical image contrast, which works just like the Wilson cloud chamber, to distinctively indicate the motor trajectory resulted from the generated hydrogen gas stream.A series of unusual complicated multi-phase fluid mechanics phenomena were observed. It was also identified that the main driving factor of the motors comes fromthe H2 bubbles generated at the bottom of these tiny motors, which is different from the large size self-fueled liquid metal machine. Several typical mechanisms for such unconventional Brownian-like motion phenomena were preliminarily interpreted. | Bin Yuan Sicong Tan Yixin Zhou Jing Liu | 2015 | Science Bulletin2015,60,13: | 8 |
| 3 | Spraying printing of liquid metal electronics on various clothes to compose wearable functional device显示文摘Liquid metal printing is emerging as an important tool for making wearable electronics. However, very limited academic efforts were made to fulfill such an increasing need. This paper is dedicated to present relatively complete theoretical and experimental characterizations for liquid metal spraying printing towards developing wearable electronic textile. The practical conditions of liquid metal droplets in the spraying printing process such as the jet velocity, the size distribution of droplets and their evenness degree, the morphology of droplets and their unrolling areas after impacting the substrate are quantified. The dominating factors, including the oxidation of liquid metal and the pressure force on cloth substrate during the impacting process, which ensure liquid metal firmly adhere to the cloth, are clarified. Further, various clothes are comparatively investigated to test their capabilities in printing liquid metal conductors, where the resistance difference can be over thousand-fold. In addition to interpreting the basic mechanisms and performances of the spraying printing, two programmable flexible circuits with specifically designed functions such as blinking LED lighting and wireless infrared temperature measurement via current manufacture technology were also demonstrated and evaluated for their washable ability. With the realization of wearable modules via liquid metal printing technology, it can be expected that flexible functional devices on cloth fabricated quickly and directly would witness more broad applications in the coming time. | GUI Han TAN SiCong WANG Qian YU Yang LIU FuJun LIN Ju LIU Jing | 2017 | Science China(Technological Sciences)2017,60,2: | 8 |
| 4 | Single-phase high-entropy intermetallic compounds(HEICs): bridging high-entropy alloys and ceramics显示文摘High-entropy intermetallic compounds(HEICs)were fabricated by mechanical alloying and spark plasma sintering to fill a knowledge gap between the traditional high-entropy alloys(HEAs)and emerging highentropy ceramics(HECs).Notably,several four-or five-component equimolar aluminides,such as the B2-phase(Fe1/5 Co1/5 Ni1/5 Mn1/5 Cu1/5)Al,have been made into single-phase HEICs for the first time.Thermodynamic modeling and a reversible,temperature-dependent,phase-stability experiment suggest that such B2-phase HEICs are entropy-stabilized phases.The structure of these HEICs resembles that of HECs with high-entropy mixing of fo ur or five elements of nearly equal fractions in one and only one sublattice,but with significant(10%)anti-site defects(differing from typical HECs).A new phase stability rule for forming single B2-phase HEICs is proposed.Five additional HEICs of predominantly D022 phases have also been made.This study broadens the families of equimola r,single-phase,high-entropy materials that have been successfully fabricated. | Naixie Zhou Sicong Jiang Timothy Huang Mingde Qin Tao Hu Jian Luo | 2019 | Science Bulletin2019,64,12: | 8 |
| 5 | Electrically driven chip cooling device using hybrid coolants of liquid metal and aqueous solution显示文摘Heat dissipation of electronic devices keeps as a tough issue for decades. As the most classical coolant in a convective heat transfer process, water has been widely adopted which however inherits with limited thermal conductivity and relies heavily on mechanical pump. As an alternative, the room temperature liquid metal was increasingly emerging as an important coolant to realize much stronger enhanced heat transfer. However, its thermal capacity is somewhat lower than that of water, which may restrict the overall cooling performance. In addition, the high cost by taking too much amount of liquid metal into the device also turns out to be a big concern for practical purpose. Here, through combining the individual merits from both the liquid metal with high conductivity and water with large heat capacity, we proposed and demonstrated a new conceptual cooling device that integrated hybrid coolants, radiator and annular channel together for chip thermal management. Particularly, the electrically induced actuation effect of liquid metal was introduced as the only flow driving strategy, which significantly simplified the whole system design. This enables the liquid metal sphere and its surrounding aqueous solution to be quickly accelerated to a large speed under only a very low electric voltage. Further experiments demonstrated that the cooling device could effectively maintain the temperature of a hotpot(3.15 W/cm^2) below 55oC with an extremely small power consumption rate(0.8 W). Several situations to simulate the practical working of the device were experimentally explored and a theoretical thermal resistance model was established to evaluate its heat transfer performance. The present work suggests an important way to make highly compact chip cooling device, which can be flexibly extended into a wide variety of engineering areas. | TAN SiCong ZHOU YiXin WANG Lei LIU Jing | 2016 | Science China(Technological Sciences)2016,59,2: | 7 |
| 6 | False data injection attacks against smart grid state estimation:Construction, detection and defense显示文摘As a typical representative of the so-called cyber-physical system,smart grid reveals its high efficiency,robustness and reliability compared with conventional power grid.However,due to the deep integration of electrical components and computinginformation in cyber space,smart grid is vulnerable to malicious attacks,especially for a type of attacks named false data injection attacks(FDIAs).FDIAs are capable of tampering meter measurements and affecting the results of state estimation stealthily,which severely threat the security of smart grid.Due to the significantinfluence of FDIAs on smart grid,the research related to FDIAs has received considerable attention over the past decade.This paper aims to summarize recent advances in FDIAs against smart grid state estimation,especially from the aspects of background materials,construction methods,detection and defense strategies.Moreover,future research directions are discussed and outlined by analyzing existing results.It is expected that through the review of FDIAs,the vulnerabilities of smart grid to malicious attacks can be further revealed and more attention can be devoted to the detection and defense of cyber-physical attacks against smart grid. | ZHANG Meng SHEN Chao HE Ning HAN SiCong LI Qi WANG Qian GUAN XiaoHong | 2019 | Science China(Technological Sciences)2019,62,12: | 6 |
| 7 | Deep Model Compression for Mobile Platforms:A Survey显示文摘Despite the rapid development of mobile and embedded hardware, directly executing computationexpensive and storage-intensive deep learning algorithms on these devices’ local side remains constrained for sensory data analysis. In this paper, we first summarize the layer compression techniques for the state-of-theart deep learning model from three categories: weight factorization and pruning, convolution decomposition, and special layer architecture designing. For each category of layer compression techniques, we quantify their storage and computation tunable by layer compression techniques and discuss their practical challenges and possible improvements. Then, we implement Android projects using TensorFlow Mobile to test these 10 compression methods and compare their practical performances in terms of accuracy, parameter size, intermediate feature size,computation, processing latency, and energy consumption. To further discuss their advantages and bottlenecks,we test their performance over four standard recognition tasks on six resource-constrained Android smartphones.Finally, we survey two types of run-time Neural Network(NN) compression techniques which are orthogonal with the layer compression techniques, run-time resource management and cost optimization with special NN architecture,which are orthogonal with the layer compression techniques. | Kaiming Nan Sicong Liu Junzhao Du Hui Liu | 2019 | Tsinghua Science and Technology2019,24,6: | 6 |
| 8 | Characteristics and significance of the penecontemporaneous karst in lacustrine carbonate, Da'anzhai Member, Lower Jurassic, Beibei area, eastern Sichuan Basin显示文摘There are few reports about the penecontemporaneous karst of the lacustrine carbonate of Da'anzhai Member which developed on the top of Lower Jurassic Ziliujing Formation,eastern Sichuan Basin.Based on the analysis of the macroscopic and microscopic characteristics of Heping Reservoir section in Beibei area,It is discovered that the penecontemporaneous karst in the lacustrine carbonate,Da'anzhai Member,and its characters as follows:(1)The dissolved fractures and karrens are common,which have been filled with vadose silts,bioclasts,terrigenous quartzes,crystal and intergrown calcites;(2)The penecontemporaneous karstification mainly occurs in the micrites and shell limestones of the middle and upper part of the shallowing-upward sequence,and the desiccation cracks occur in some shallowing-upward sequences;(3)Three meteoric-water diagenetic lenses are identified in this section.By further study we also find the factures,stylolite and burial dissolution pores occur along the karst system(tubes,conduits and caves of the karst).And the asphalt not only fills the stylolites and fractures,but also is mixed with the vadose silt in the karst system,although the pore space formed by penecontemporaneous karstification is filled with vadose material and cements.Therefore it is concluded that the development and modification of the tight lacustrine carbonate reservoir of Da'anzhai Member,to some extent,are relevant with the penecontemporaneous karstification,and the penecontemporaneous karst reservoir may develop in the buried Da'anzhai carbonate of the basin. | Chengpeng Su Xiucheng Tan Kailan Shi Juan Zou Feifan Lu Sicong Luo Hao Tang Xinyu Zhang | 2017 | Petroleum2017,3,3: | 5 |
| 9 | Influence of SO_2 in incineration flue gas on the sequestration of CO_2 by municipal solid waste incinerator fly ash显示文摘The influence of CO2 content and presence of SO2 on the sequestration of CO2 by municipal solid waste incinerator(MSWI) fly ash was studied by investigating the carbonation reaction of MSWI fly ash with different combinations of simulated flue gas.The reaction between fly ash and 100% CO2 was relatively fast;the uptake of CO2 reached 87g CO2/kg ash,and the sequestered CO2 could be entirely released at high temperatures.When CO2 content was reduced to 12%,the reaction rate decreased;the uptake fell to 41g CO2/kg ash,and 70.7% of the sequestered CO2 could be released.With 12% CO2 in the presence of SO2,the reaction rate significantly decreased;the uptake was just 17g CO2/kg ash,and only 52.9% of the sequestered CO2 could be released.SO2 in the simulated gas restricted the ability of fly ash to sequester CO2 because it blocked the pores of the ash. | Jianguo Jiang Sicong Tian Chang Zhang | 2013 | Journal of Environmental Sciences2013,25,4: | 4 |
| 10 | Sparsity-Aware Channel Estimation for mmWave Massive MIMO: A Deep CNN-Based Approach显示文摘The deep convolutional neural network(CNN)is exploited in this work to conduct the challenging channel estimation for mmWave massive multiple input multiple output(MIMO)systems.The inherent sparse features of the mmWave massive MIMO channels can be extracted and the sparse channel supports can be learnt by the multi-layer CNN-based network through training.Then accurate channel inference can be efficiently implemented using the trained network.The estimation accuracy and spectrum efficiency can be further improved by fully utilizing the spatial correlation among the sparse channel supports of different antennas.It is verified by simulation results that the proposed deep CNN-based scheme significantly outperforms the state-of-the-art benchmarks in both accuracy and spectrum efficiency. | Sicong Liu Xiao Huang | 2021 | China Communications2021,18,6: | 4 |
| 11 | Alternating electric field actuated oscillating behavior of liquid metal and its application显示文摘As a class of newly emerging functional material,Gallium based liquid metals have attracted increasing attentions in many fields,such as chip cooling,printed electronics and microfluidics,etc.Particularly,the motion control of liquid metal droplet has been recently tried for its importance in microelectromechanical system(MEMS),microfluidics and potential use in micro-machine or reconfigurable soft robot.This paper is dedicated to explore the motion behavior of liquid metal droplet under AC electric field.The quickly induced oscillation phenomena of liquid metal droplet and surrounding electrolyte solution were observed and the major factors to influence such behaviors are theoretically interpreted and experimentally investigated,including the size of the liquid metal droplet,electrode voltage,electrolyte solution concentration and AC signal frequency etc.Moreover,some typical features to distinguish AC filed actuation with DC field are observed,such as intensive fluid waving induced by the resonance stimulation,and the efficient inhibition of solution electrolysis.Finally,two important applications of adopting AC induced surface oscillation of liquid metal droplet to develop solution mixer as well as fluidic pump were demonstrated which successfully avoid gas generation inside electrolyte environment.The bulk oscillation effects of liquid metal as clarified here could be very useful in a variety of areas such as solution disturbance and mixing,and fluid oscillator or pump etc. | YANG XiaoHu TAN SiCong YUAN Bin LIU Jing | 2016 | Science China(Technological Sciences)2016,59,4: | 4 |
| 12 | Adaptive optics two-photon microscopy enables near-diffraction-limited and functional retinal imaging in vivo显示文摘In vivo fundus imaging offers non-invasive access to neuron structures and biochemical processes in the retina.However,optical aberrations of the eye degrade the imaging resolution and prevent visualization of subcellular retinal structures.We developed an adaptive optics two-photon excitation fluorescence microscopy(AO-TPEFM)system to correct ocular aberrations based on a nonlinear fluorescent guide star and achieved subcellular resolution for in vivo fluorescence imaging of the mouse retina.With accurate wavefront sensing and rapid aberration correction,AOTPEFM permits structural and functional imaging of the mouse retina with submicron resolution.Specifically,simultaneous functional calcium imaging of neuronal somas and dendrites was demonstrated.Moreover,the timelapse morphological alteration and dynamics of microglia were characterized in a mouse model of retinal disorder.In addition,precise laser axotomy was achieved,and degeneration of retinal nerve fibres was studied.This highresolution AO-TPEFM is a promising tool for non-invasive retinal imaging and can facilitate the understanding of a variety of eye diseases as well as neurodegenerative disorders in the central nervous system. | Zhongya Qin Sicong He Chao Yang Jasmine Sum-Yee Yung Congping Chen Christopher Kai-Shun Leung Kai Liu Jianan Y.Qu | 2020 | Light(Science & Applications)2020,9,1: | 4 |
| 13 | Surface effects on in-shoe plantar pressure and tibial impact during running显示文摘目的:探讨在不同表面上跑步对足底压力和胫骨加速度的影响。方法:13位男性跑步者被要求分别在水泥地、塑胶跑道、天然草地、跑步机以及配备EVA缓冲衬垫物的跑步机上以12 km/h的速度进行慢跑。用足底压力测试系统和安放在胫骨粗隆的加速度计,记录和分析足底压力与胫骨冲击的特点。结果:第一和第二足底压力峰值(发生时间)、压力时间积分、峰值压力分布在混凝土、塑胶、草地和正常的跑步机的表面间没有明显差异。在5种不同测试表面下,峰值加速度正值也无显著差异。但相比于混凝土表面,在配备EVA缓冲衬垫物的跑步机上跑步能明显减小在冲击阶段的足底压力第一峰值和压力积分(p<0.05)。上述结果可进一步归因为足后跟区域峰值压力下降(P<0.05)。结论:运动表面和下肢冲击之间也许并无必然关系。然而值得注意的是,在解释足底压力的表现及将其运用到陆地表面的跑步运动中时应考虑不同跑步机表面的影响。 | Weijie Fu Ying Fang David Ming Shuo Liu Lin Wang Sicong Ren Yu Liu | 2015 | Journal of Sport and Health Science2015,4,4: | 4 |
| 14 | Dual-shot dynamics and ultimate frequency of all-optical magnetic recording on GdFeCo显示文摘Although photonics presents the fastest and most energy-efficient method of data transfer,magnetism still offers the cheapest and most natural way to store data.The ultrafast and energy-efficient optical control of magnetism is presently a missing technological link that prevents us from reaching the next evolution in information processing.The discovery of all-optical magnetization reversal in GdFeCo with the help of 100fs laser pulses has further aroused intense interest in this compelling problem.Although the applicability of this approach to high-speed data processing depends vitally on the maximum repetition rate of the switching,the latter remains virtually unknown.Here we experimentally unveil the ultimate frequency of repetitive all-optical magnetization reversal through time-resolved studies of the dual-shot magnetization dynamics in Gd27 Fe63.87 C09.T3.Varying the intensities of the shots and the shotto-shot separation,we reveal the conditions for ultrafast writing and the fastest possible restoration of magnetic bits.It is shown that although magnetic writing launched by the first shot is completed after 100 ps,a reliable rewriting of the bit by the second shot requires separating the shots by at least 300 ps.Using two shots partially overlapping in space and minimally separated by 300 ps,we demonstrate an approach for GHz magnetic writing that can be scaled down to sizes below the diffraction limit. | Sicong Wang Chen Wei\Yuanhua Feng Hongkun Cao Wenzhe Li Yaoyu Cao Bai-Ou Guan Arata Tsukamoto Andrei Kirilyuk Alexey VKimel Xiangping Li | 2021 | Light(Science & Applications)2021,10,1: | 3 |
| 15 | Surface Oxygen Injection in Tin Disulfide Nanosheets for Efficient CO_(2) Electroreduction to Formate and Syngas显示文摘Surface chemistry modification represents a promising strategy to tailor the adsorption and activation of reaction intermediates for enhancing activity.Herein,we designed a surface oxygen-injection strategy to tune the electronic structure of SnS_(2) nanosheets,which showed effectively enhanced electrocatalytic activity and selectivity of CO_(2) reduction to formate and syngas(CO and H_(2)).The oxygen-injection SnS_(2) nanosheets exhibit a remarkable Faradaic efficiency of 91.6%for carbonaceous products with a current density of 24.1 mA cm^(−2) at−0.9 V vs RHE,including 83.2%for formate production and 16.5%for syngas with the CO/H_(2) ratio of 1:1.By operando X-ray absorption spectroscopy,we unravel the in situ surface oxygen doping into the matrix during reaction,thereby optimizing the Sn local electronic states.Operando synchrotron radiation infrared spectroscopy along with theoretical calculations further reveals that the surface oxygen doping facilitated the CO_(2) activation and enhanced the affinity for HCOO*species.This result demonstrates the potential strategy of surface oxygen injection for the rational design of advanced catalysts for CO_(2) electroreduction. | Tao Chen Tong Liu Tao Ding Beibei Pang Lan Wang Xiaokang Liu Xinyi Shen Sicong Wang Dan Wu Dong Liu Linlin Cao Qiquan Luo Wei Zhang Wenkun Zhu Tao Yao | 2021 | Nano-Micro Letters2021,13,11: | 3 |
| 16 | Traditional Chinese medicine molecule-assisted chemical synthesis of fluorescent anti-cancer silicon nanoparUcles显示文摘 | Xiaoyuan Ji Daoxia Guo Bin Song Sicong Wu Binbin Chu Yuanyuan Su Yao He | 2018 | Nano Research2018,11,10: | 3 |
| 17 | MARVEL:Multi-Agent Reinforcement Learning for VANET Delay Minimization显示文摘In urban Vehicular Ad hoc Networks(VANETs),high mobility of vehicular environment and frequently changed network topology call for a low delay end-to-end routing algorithm.In this paper,we propose a Multi-Agent Reinforcement Learning(MARL)based decentralized routing scheme,where the inherent similarity between the routing problem in VANET and the MARL problem is exploited.The proposed routing scheme models the interaction between vehicles and the environment as a multi-agent problem in which each vehicle autonomously establishes the communication channel with a neighbor device regardless of the global information.Simulation performed in the 3GPP Manhattan mobility model demonstrates that our proposed decentralized routing algorithm achieves less than 45.8 ms average latency and high stability of 0.05%averaging failure rate with varying vehicle capacities. | Chengyue Lu Zihan Wang Wenbo Ding Gang Li Sicong Liu Ling Cheng | 2021 | China Communications2021,18,6: | 2 |
| 18 | Diffractive photonic applications mediated by laser reduced graphene oxides显示文摘 | Sicong Wang Xueying Ouyang Ziwei Feng Yaoyu Cao Min Gu Xiangping Li | 2018 | Opto-Electronic Advances2018,1,2: | 2 |
| 19 | Smart Care: Energy-Efficient Long-Term Physical Activity Tracking Using Smartphones显示文摘Lack of physical activity is becoming a killer of our healthy life. As a solution for this negative impact,we propose Smart Care to help users to set up a healthy physical activity habit. Smart Care can monitor a user's activities over a long time, and then provide activity quality assessment and suggestion. Smart Care consists of three parts, activity recognition, energy saving, and health feedback. Activity recognition can recognize nine kinds of daily activities. A hybrid classifier that uses less power and memory with satisfactory accuracy was designed and implemented by utilizing the periodicity of target activity. In addition, a learning-based energy saver was introduced to reduce energy consumption by adjusting sampling rates and the set of features adaptively. Based on the type and duration of the activity recorded, health feedback in terms of the calorie burned was given. The system could provide quantitative activity quality assessment and recommend future physical activity plans. Through extensive real-life testing, the system is shown to achieve an average recognition accuracy of 98.0% with a minimized energy expenditure. | Hui Liu Rui Li Sicong Liu Shibian Tian Junzhao Du | 2015 | Tsinghua Science and Technology2015,20,4: | 2 |
| 20 | High-resolution two-photon transcranial imaging of brain using direct wavefront sensing显示文摘Imaging of the brain in its native state at high spatial resolution poses major challenges to visualization techniques.Two-photon microscopy integrated with the thinned-skull or optical clearing skull technique provides a minimally invasive tool for in vivo imaging of the cortex of mice without activating immune response and inducing brain injury.However,the imaging contrast and spatial resolution are severely compromised by the optical heterogeneity of the skull,limiting the imaging depth to the superficial layer.In this work,an optimized configuration of an adaptive optics two-photon microscope system and an improved wavefront sensing algorithm are proposed for accurate correction for the aberrations induced by the skull window and brain tissue.Using this system,we achieved subcellular resolution transcranial imaging of layer 5 pyramidal neurons up to 700μm below pia in living mice.In addition,we investigated microglia–plaque interaction in living brain of Alzheimer’s disease and demonstrated high-precision laser dendrotomy and single-spine ablation. | CONGPING CHEN ZHONGYA QIN SICONG HE SHAOJUN LIU SHUN-FAT LAU WANJIE WU DAN ZHU NANCY Y.IP JIANAN Y.QU | 2021 | Photonics Research2021,9,6: | 2 |