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| 1 | Three dimensional shear wave velocity structure of the crust and upper mantle beneath China from ambient noise surface wave tomography显示文摘We determine the three-dimensional shear wave velocity structure of the crust and upper mantle in China using Green's functions obtained from seismic ambient noise cross-correlation.The data we use are from the China National Seismic Network,global and regional networks and PASSCAL stations in the region.We first acquire cross-correlation seismograms between all possible station pairs.We then measure the Rayleigh wave group and phase dispersion curves using a frequency-time analysis method from 8 s to 60 s.After that,Rayleigh wave group and phase velocity dispersion maps on 1° by 1° spatial grids are obtained at different periods.Finally,we invert these maps for the 3-D shear wave velocity structure of the crust and upper mantle beneath China at each grid node.The inversion results show large-scale structures that correlate well with surface geology.Near the surface,velocities in major basins are anomalously slow,consistent with the thick sediments.East-west contrasts are striking in Moho depth.There is also a fast mid-to-lower crust and mantle lithosphere beneath the major basins surrounding the Tibetan plateau (TP) and Tianshan (Junggar,Tarim,Ordos,and Sichuan).These strong blocks,therefore,appear to play an important role in confining the deformation of the TP and constraining its geometry to form its current triangular shape.In northwest TP in Qiangtang,slow anomalies extend from the crust to the mantle lithosphere.Meanwhile,widespread,a prominent low-velocity zone is observed in the middle crust beneath most of the central,eastern and southeastern Tibetan plateau,consistent with a weak (and perhaps mobile) middle crust. | Xinlei Sun Xiaodong Song Sihua Zheng Yingjie Yang Michael H. Ritzwoller | 2010 | Earthquake Science2010，23，5： | 28 |
| 2 | Explicit diagnosis of the local ozone production rate and the ozone-NOx-VOC sensitivities显示文摘In the troposphere, ozone is a harmful gas compound to both human health and vegetation. Ozone is produced from the reaction of NO_x(@NO + NO_2) and VOCs(volatile organic compounds) with light. Due to the highly nonlinear relationships between ozone and its precursors, proper ozone mitigation relies on the knowledge of chemical mechanisms. In this study, an observation-based method is used to simulate ozone formation and elucidate its controlling factors for a rural site on the North China Plain. The instantaneous ozone production rate is calculated utilizing a box model using the dataset obtained from the Wangdu campaign. First, the model was operated in a time-dependent mode to calculate the ozone production rate at each time stamp. The calculated ozone formation rate showed a diurnal average maximum value of 17 ppbv/h(1-h diurnal averaged). The contribution of individual peroxy radicals to ozone production was analyzed. In addition, the functional dependence of calculated P(O_3) reveals that ozone production was in a NO_x-limited regime during the campaign. Furthermore, the missing peroxy radical source will further extend NO_x-limited conditions to earlier in the day, making NO_xlimitation dominate more of a day than the current chemical model predicts. Finally, a multiple scenarios mode,also known as EKMA(empirical kinetic modeling approach), was used to simulate the response of P(O_3) to the imaginary change in precursor concentrations. We found that ozone production was in the NO_x-limited region. However, the use of NO_2 measured by the molybdenum converter and/or the absence of a peroxy radical source in the current chemical model could over-emphasize the VOC-limited effect on ozone production. | Zhaofeng Tan Keding Lu Huabin Dong Min Hu Xin Li Yuhan Liu Sihua Lu Min Shao Rong Su Haichao Wang Yusheng Wu Andreas Wahner Yuanhang Zhang | 2018 | Science Bulletin2018，63，16： | 25 |
| 3 | Spatial segmentation characteristic of focal mechanism of aftershock sequence of Wenchuan Earthquake显示文摘Moment tensor solutions of 88 earthquakes were determined by using the broadband waveform data recorded in six stations within 450 km around the Wenchuan Earthquake sequence by means of the time domain moment tensor inversion method.It was found that the type of the focal mechanism solution is characteristic of obvious spatial segmentation.There are six segments along the main rupture zone from southwest to northeast,where initially the focal mechanism is of main thrust type,finally of main right-lateral strike-slip type and between these two areas there is a transition zone characterized in multiple types of focal mechanisms appearing in turn.Earthquakes of left-lateral strike-slip type perpendicular to the main rupture zone occurred near Xiaoyudong Town.The stress field of each segment is inversed by means of the FMSI program,and it was found that,along the main rupture zone from southwest to northeast,the direction of the maximum principal stress is gradually changing from near EW to NW-SE,and finally changing back to near EW. | WANG QinCai CHEN ZhangLi ZHENG SiHua | 2009 | Chinese Science Bulletin2009，54，13： | 20 |
| 4 | Carbonyl emissions from heavy-duty diesel vehicle exhaust in China and the contribution to ozone formation potential显示文摘Fifteen heavy-duty diesel vehicles were tested on chassis dynamometer by using typical heavy duty driving cycle and fuel economy cycle. The air from the exhaust was sampled by 2,4-dinitrophenyhydrazine cartridge and 23 carbonyl compounds were analyzed by high performance liquid chromatography. The average emission factor of carbonyls was 97.2 mg/km, higher than that of light-duty diesel vehicles and gasoline-powered vehicles. Formaldehyde, acetaldehyde, acetone and propionaldehyde were the species with the highest emission factors. Main influencing factors for carbonyl emissions were vehicle type, average speed and regulated emission standard, and the impact of vehicle loading was not evident in this study. National emission of carbonyls from diesel vehicles exhaust was calculated for China, 2011, based on both vehicle miles traveled and fuel consumption. Carbonyl emission of diesel vehicle was estimated to be 45.8 Gg, and was comparable to gasolinepowered vehicles(58.4 Gg). The emissions of formaldehyde, acetaldehyde and acetone were 12.6, 6.9, 3.8 Gg, respectively. The ozone formation potential of carbonyls from diesel vehicles exhaust was 537 mg O3 /km, higher than 497 mg O3 /km of none-methane hydrocarbons emitted from diesel vehicles. | Dong Dong Min Shao Yue Li Sihua Lu Yanjun Wang Zhe Ji Dagang Tang | 2014 | Journal of Environmental Sciences2014，26，1： | 20 |
| 5 | Emission factors of gaseous carbonaceous species from residential combustion of coal and crop residue briquettes显示文摘Experiments were performed to measure the emission factors (EFs) of gaseous carbonaceous species, such as CO2, CO, CH4, and non-methane volatile organic compounds (NMVOCs), from the combustion of five types of coal of varying organic maturity and two types of biomass briquettes under residential burning conditions. Samples were collected in stainless steel canisters and 2,4- dinitrophenylhydrazine (DNPH) cartridges and were analyzed by GC FID/MS and HPLC, respectively. The EFs from crop residue briquette burning were generally higher than those from coals, with the exception of CO2. The dominant NMVOC species identified in coal smoke were carbonyls (41.7%), followed by C2 unsaturated hydrocarbons (29.1%) and aromatics (12.1%), while C2 unsaturated hydrocarbons were the dominant species (68.9%) emitted from the combustion of crop residue briquettes, followed by aromatics (14.4%). A comparison of burning normal crop residues in stoves and the open field indicated that briquettes emitted a larger proportion of ethene and acetylene. Both combustion efficiency and coal organic maturity had a significant impact on NMVOC EFs from burning coal: NMVOC emissions increased with increasing coal organic maturity but decreased as the combustion efficiency improved. Emissions from the combustion of crop residue briquettes from stoves occurred mainly during the smoldering process, with low combustion efficiency. Therefore, an improved stove design to allow higher combustion efficiency would be beneficial for reducing emissions of carbonaceous air pollutants. | Qin WANG Chunmei GENG Sihua LU Wentai CHEN Min SHAO | 2013 | Frontiers of Environmental Science & Engineering2013，7，1： | 17 |
| 6 | Reactivity of ambient volatile organic compounds(VOCs) in summer of 2004 in Beijing显示文摘周围的不稳定的有机化合物(VOC ) 在 2004 的夏天在北京在六个地点被取样并且由 GCMS 分析了。73 的化学反应性确定了 VOC 种类被评估由哦损失率(LOH ) 和臭氧形成潜力(OFP ) 。顶 15 活性组分,主要链烯和 aromatics,被这二个方法识别,并且占了 VOC 的超过 70% 全部的反应。在城市的区域,异戌二烯是大多数活性组分以哦损失率,贡献 11.4% 到 VOC 的 LOH。当时甲苯,为 9.4% OFP 的财务,看起来在光化过程有一个长期的角色。Tongzhou 地点被本地化学工业显然影响,但是另外的五个地点显示出主要车辆的排出物影响的典型城市的特征。 | Shan Huang Min Shao Sihua Lu Ying Liu | 2008 | Chinese Chemical Letters2008，19，5： | 14 |
| 7 | Screening the emission sources of volatile organic compounds (VOCs) in China by multi-effects evaluation显示文摘 | He NIU Ziwei MO Min SHAO Sihua LU ShaodongXIE | 2016 | Frontiers of Environmental Science & Engineering2016，10，5： | 11 |
| 8 | Investigation of carbonyl compound sources at a rural site in the Yangtze River Delta region of China显示文摘Carbonyl compounds are important intermediates in atmospheric photochemistry, but their primary sources are still not understood well. In this work, carbonyls, hydrocarbons,and alkyl nitrates were continuously measured during November 2011 at a rural site in the Yangtze River Delta region of China. Mixing ratios of carbonyls and hydrocarbons showed large fluctuations during the entire measurement. The average level for total measured volatile organic compounds during the pollution episode from 25 th to 27 th November, 2011 was 91.6 ppb, about 7 times the value for the clean period of 7th–8th, November, 2011. To preliminarily identify toluene sources at this site, the emission ratio of toluene to benzene(T/B) during the pollution episode was determined based on photochemical ages derived from the relationship of alkyl nitrates to their parent alkanes. The calculated T/B was5.8 ppb/ppb, significantly higher than the values of 0.2–1.7 ppb/ppb for vehicular exhaust and other combustion sources, indicating the dominant influence of industrial emissions on ambient toluene. The contributions of industrial sources to ambient carbonyls were then calculated using a multiple linear regression fit model that used toluene and alkyl nitrates as respective tracers for industrial emission and secondary production. During the pollution episode, 18.5%, 69.0%, and 52.9% of measured formaldehyde, acetaldehyde, and acetone were considered to be attributable to industrial emissions. The emission ratios relative to toluene for formaldehyde, acetaldehyde, and acetone were determined to be 0.10, 0.20 and0.40 ppb/ppb, respectively. More research on industrial carbonyl emission characteristics is needed to understand carbonyl sources better. | Ming Wang Wentai Chen Min Shao Sihua Lu Limin Zeng Min Hu | 2015 | Journal of Environmental Sciences2015，27，2： | 8 |
| 9 | Major reactive species of ambient volatile organic compounds (VOCs) and their sources in Beijing显示文摘Volatile organic compounds (VOCs) are important precursors of atmospheric chemical processes. As a whole mixture, the ambient VOCs show very strong chemical reactivity. Based on OH radical loss rates in the air, the chemical reactivity of VOCs in Beijing was calculated. The results revealed that alkenes, accounting for only about 15% in the mixing ratio of VOCs, provide nearly 75% of the reactivity of ambient VOCs and the C4 to C5 alkenes were the major reactive species among the alkenes. The study of emission characteristics of various VOCs sources indicated that these alkenes are mainly from vehicle exhaust and gasoline evaporation. The reduction of alkene species in these two sources will be effective in photochemical pollution control in Beijing. | SHAO Min FU Linlin LIU Ying LU Sihua ZHANG Yuanhang TANG Xiaoyan | 2005 | Science China Earth Sciences2005，48，z2： | 7 |
| 10 | Shear velocity structure of crust and uppermost mantle in China from surface wave tomography using ambient noise and earthquake data显示文摘We present a 3D model of shear velocity of crust and upper mantle in China and surrounding regions from surface wave tomography.We combine dispersion measurements from ambient noise correlation and traditional earthquake data.The stations include the China National Seismic Network,global networks,and all the available PASSCAL stations in the region over the years.The combined data sets provide excellent data coverage of the region for surface wave measurements from 8 to 120 s,which are used to invert for 3D shear wave velocity structure of the crust and upper mantle down to about150 km.We also derive new models of the study region for crustal thickness and averaged S velocities for upper,mid,and lower crust and the uppermost mantle.The models provide a fundamental data set for understanding continental dynamics and evolution.The tomography results reveal significant features of crust and upper mantle structure,including major basins,Moho depth variation,mantle velocity contrast between eastern and western North China Craton,widespread low-velocity zone in midcrust in much of the Tibetan Plateau,and clear velocity contrasts of the mantle lithosphere between north and southern Tibet with significant E–W variations.The low velocity structure in the upper mantle under north and eastern TP correlates with surface geological boundaries.A patch of high velocity anomaly is found under the eastern part of the TP,which may indicate intact mantle lithosphere.Mantle lithosphere shows striking systematic change from the western to eastern North China Craton.The Tanlu Fault appears to be a major lithosphere boundary. | Zhen J.Xu Xiaodong Song Sihua Zheng | 2013 | Earthquake Science2013，26，5： | 7 |
| 11 | Thermally confined shell coating amplifies the photoacoustic conversion efficiency of nanoprobes显示文摘有效探查 / 对比代理人为好表演的 photoacoustic (PA ) 是高度合乎需要的成像,一根探针的 PA 信号振幅被它的光吸收和变换效率从在哪儿统治,吸收了激光精力到声学的波浪。Nanoprobes PA 精力变换的一个唯一的微观机构一直不由于尺寸效果,然而,它有是表明并且有效地利用了的份量上。这里,我们为 plasmonmediated nanoprobes 的 PA 信号生产过程的现在的量的模拟基于有限元素分析方法,它被执行到提供他们的 PA 变换微观机构的深理解。而且,我们建议一个方法通过热地限制的壳涂层的使用放大 nanoprobes 的 PA 变换效率,它在常规探针的以外允许变换效率的活跃控制。另外,我们在壳性质上推出了变换效率的依赖。Gold-nanoparticles/polydimethylsiloxane nanocomposites 试验性地在胶化形式被综合,证实我们的想法和模拟结果的缩微胶卷同意了实验。我们的工作与改进变换效率为 nanoprobes 的合理设计和优化铺平道路。 | Yujiao Shi Huan Qin Sihua Yang Da Xing | 2016 | Nano Research2016，9，12： | 7 |
| 12 | Optimal quality level,order quantity and selling price for the retailer in a two-level supply chain显示文摘For a classical order quantity/pricing problem,we present a geometric programming(GP)approach to find the optimal selling price,order quantity and quality level to maximize the profit for the retail firm.Traditional models such as EOQ are not able to handle the nonlinearity of costs and demand.We adopt the GP approach and make a proper transformation of the model so as to solve this classical problem and obtain the global optimal solution.In addition to the optimal solutions,we also perform a sensitivity analysis.The study shows once more that GP is an excellent approach when decision variables interact in a nonlinear,especially exponential manner. | Sihua Zhou Guohua Wan Pengzhu Zhang Yuan Li | 2014 | Journal of Management Analytics2014，1，3： | 6 |
| 13 | Pose-relay videometrics based ship deformation measurement system and sea trials显示文摘The measurement of ship deformation has been a difficult problem for the global ship building industry and navigation field research.So far,an effective and proven method for measuring 3D position and attitude deformation remains unavailable.This article proposes an innovative pose-relay videometrics measurement system for ship deformation on the basis of primary research and experimental validation.The system offers solutions to the important technical problems such as infrared marker manufacture,high-precision detection and multi-camera synchronization and control.Sea trials were carried out,and reasonable,long-term,and continuous 3D data of position and attitude deformations between a given deck point and the ship reference,and between the ship's head and the stern were acquired for the first time.The experiments have highlighted the considerable applicability of the proposed method of deformation measurement and long-term monitoring of ships and similar large structures. | JIANG GuangWen FU SiHua CHAO ZhiChao YU QiFeng | 2011 | Chinese Science Bulletin2011，56，1： | 6 |
| 14 | Literature-based analysis on relationship of symptoms,drugs and therapies in treatment of intestinal diseases显示文摘OBJECTIVE:To evaluate clinical articles published in the past 30 years using the Traditional Chinese Medicine(TCM)theory of the lung being connected with large intestine to treat intestinal diseases.We also analyzed the relationship between symptoms,drugs and therapies with data-excavating technology to aid management.METHODS:After retrieving relevant clinical articles,we set up a database,used Microsoft Structured Query Language Server 2005 Analysis Services as a data-excavating tool,and applied the association rule to study the relationship between the symptoms,drugs and therapies of intestinal diseases.RESULTS:The key symptoms of dyschesia,constipation,abdominal fullness,fatigue and pale tongue could be treated with Kuxingren(Semen Armeniacae Amarum),Huangqi(Radix Astragali Mongolici)and Gualou(Fructus et Semen Trichosanthis)to invigorate Qi and moisten the intestine.Among these agents,Kuxingren(Semen Armeniacae Amarum)was used most frequently.Clearing Fu-organs was the most prevalent therapy for abdominal fullness,dyschesia,constipation and red tongue.Clearing Fu-organs could be achieved with Kuxingren(Semen Armeniacae Amarum)and Gualou(Fructus et Semen Trichosanthis),whereas Qi could be invigorated using Huangqi(Radix Astragali Mongolici),Gancao(Radix Glycyrrhizae),Baizhu(Rhizoma Atractylodis Macrocephalae)and Kuxingren(Semen Armeniacae Amarum).Moistening the intestine was possible with Kuxingren(SemenArmeniacae Amarum),Huomaren(Fructus Cannabis)and Jiegeng(Radix Platycodi).Also,moistening the lungs was done with Kuxingren(Semen Armeniacae Amarum),ventilating the lungs with Kuxingren(Semen Armeniacae Amarum)and Gualou(Fructus et Semen Trichosanthis),and nourishing the lungs with Huangqi(Radix Astragali Mongolici),Gancao(Radix Glycyrrhizae)and Kuxingren(Semen Armeniacae Amarum).These data demonstrated that Kuxingren(SemenArmeniacaeAmarum)was a key agent.CONCLUSION:Our analyses of the literature showed clear relationships between symptoms(constipation,dyschesia,abdominal fullness),drugs[Gualou(Fructus et Semen Trichosanthis),Kuxingren(Semen Armeniacae Amarum),Huangqi(Radix Astragali Mongolici)]and therapies(moistening the intestine,clearing Fu-organs,invigorating Qi,ventilating the lungs). | Luan Gao Jian Wang Yong Deng Fenggang Li Sihua Gao | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 5 |
| 15 | A displacement-relay videometric method for surface subsidence surveillance in unstable areas显示文摘When measuring the surface subsidence of unstable areas such as railroad beds and large construction fields, it is not practical to always find stable positions to install measurement instruments. Yet installing those instruments in unstable positions will cause measurement errors or even the complete failure of long-term subsidence surveillance. In this paper, the innovative concept and its method of 'displacement-relay videometrics' are proposed. With the method, a double-headed camera is designed, and two constraints, the 'fixation constraint' and the 'homologous constraint', are established to construct the displacement-relay measurement equations, which can concurrently give the subsidence of the points to be measured and the positions where the cameras are fixed. The method and its measurement system are thus capable of automatically measuring the surface subsidence under the condition that the cameras are mounted on unstable locations over long durations. Therefore, the method has the broad prospect of undertaking automatic, long-term and continuous measurement for surface subsidence in engineering projects such as railroad beds, bridges and the ground beds of tall buildings. The proposed method opens a new area that cameras can be mounted on unstable platform to make high accuracy measurements, which is of great significance for applications. | YU QiFeng JIANG GuangWen SHANG Yang XU Yong LIU XiaoLin FU SiHua GUAN BangLei ZHU XianWei | 2015 | Science China(Technological Sciences)2015，58，6： | 5 |
| 16 | Chaperone-mediated autophagy and neurodegeneration:connections,mechanisms,and therapeutic implications显示文摘Lysosomes degrade dysfunctional intracellular components via three pathways: macroautophagy, microautophagy, and chaperone-mediated autophagy(CMA). Unlike the other two, CMA degrades cytosolic proteins with a recognized KFERQ-like motif in lysosomes and is important for cellular homeostasis. CMA activity declines with age and is altered in neurodegenerative diseases. Its impairment leads to the accumulation of aggregated proteins, some of which may be directly tied to the pathogenic processes of neurodegenerative diseases. Its induction may accelerate the clearance of pathogenic proteins and promote cell survival, representing a potential therapeutic approach for the treatment of neurodegenerative diseases. In this review, we summarize the current findings on how CMA is involved in neurodegenerative diseases, especially in Parkinson's disease. | Xiaolei Liu Sihua Huang Xingqin Wang Beisha Tang Wenming Li Zixu Mao | 2015 | Neuroscience Bulletin2015，31，4： | 4 |
| 17 | Jiangtang Xiaoke granule attenuates glucose metabolism disorder via regulating endoplasmic reticulum stress in the liver of type 2 diabetes mellitus mice显示文摘OBJECTIVE:To observe the effect of Jiangtang Xiaoke(JTXK) granule on endoplasmic reticulum(ER)stress in high fat diet(HFD)-induced type 2 diabetes mellitus(T2 DM) KK-Ay mice.METHODS:KK-Ay mice were fed with HFD to induce the T2 DM model,while normal control C57 BL/6 J mice were given standard feed.Fasting blood glucose(FBG) in all mice was measured weekly and oral glucose tolerance tests(OGTTs) were performed at 4 and 10 weeks after start of treatment to determine glucose metabolism.Serum fasting insulin(FINS) and insulin sensitivity index(ISI) were measured to determine insulin sensitivity.m RNA expressions of eukaryotic initiation factor-2 alpha(e IF2α),glucose regulated protein 78(GRP78),activating transcription factor 4(ATF4),and C/EBP homology protein(CHOP) were assessed by reverse transcription polymerase chain reaction and the protein expressions of p-e IF2α,GRP78,and CHOP were assessed by Western blotting.RESULTS:JTXK granule significantly reduced FBG and free fatty acid levels and improved OGTT at the120 min of the 10-week treatment in T2 DM KK-Ay mice.FINS and Hb Alc levels were reduced and insulin sensitivities were increased in KK-Ay diabetic mice,which were improved with the treatment of JTXK granule,especially at the 7 and 3.5 g/kg doses.JTXK granule at the 3.5 g/kg dose was most effective in reducing both gene and protein expressions of e IF2α,GRP78,and CHOP.CONCLUSION:ER stress response is increased in T2 DM KK-Ay mice.Treatment with JTXK granule attenuates glucose disorders,improves insulin sensitivity,and reduces serum FFA in T2 DM KK-Ay mice.The mechanisms may be attributed to regulation of the signaling ER stress pathway via decreasing e IF2α phosphorylation and suppressing e IF2α-ATF4-CHOP activation. | Zhang Yi Mo Fangfang Zhang Dongwei Gao Sihua Zhao Dandan Yu Na Mu Qianqian Zuo Jiacheng Ma Yue | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 3 |
| 18 | Proteasome Inhibitor PS-341 Effectively Blocks Infection by the Severe Fever with Thrombocytopenia Syndrome Virus显示文摘Severe fever with thrombocytopenia syndrome(SFTS)is an emerging hemorrhagic fever disease caused by SFTSV,a newly discovered phlebovirus that is named after the disease.Currently,no effective vaccines or drugs are available for use against SFTSV infection,as our understanding of the viral pathogenesis is limited.Bortezomib(PS-341),a dipeptideboronic acid analog,is the first clinically approved proteasome inhibitor for use in humans.In this study,the antiviral efficacy of PS-341 against SFTSV infection was tested in human embryonic kidney HEK293T(293T)cells.We employed four different assays to analyze the antiviral ability of PS-341 and determined that PS-341 inhibited the proliferation of SFTSV in 293T cells under various treatment conditions.Although PS-341 did not affect the virus absorption,PS-341 treatment within a non-toxic concentration range resulted in a significant reduction of progeny viral titers in infected cells.Dual-luciferase reporter assays and Western blot analysis revealed that PS-341 could reverse the SFTSV-encoded nonstructural protein(NS)mediated degradation of retinoic acid-inducible gene-1(RIG-I),thereby antagonizing the inhibitory effect of NSs on interferons and blocking virus replication.In addition,we observed that inhibition of apoptosis promotes virus replication.These results indicate that targeting of cellular interferon pathways and apoptosis during acute infection might serve as the bases of future therapeutics for the treatment of SFTSV infections. | Sihua Liu Hongyun Liu Keke Zhang Xueping Li Yuqin Duan Zhiyun Wang Tao Wang | 2019 | Virologica Sinica2019，34，5： | 3 |
| 19 | In vivo volumetric monitoring of revascularization of traumatized skin using extended depth-of-field photoacoustic microscopy显示文摘Faster and better wound healing is a critical medical issue.Because the repair process of wounds is closely related to revascularization,accurate early assessment and postoperative monitoring are very important for establishing an optimal treatment plan.Herein,we present an extended depth-of-field photoacoustic microscopy system(E-DOF-PAM)that can achieve a constant spatial resolution and relatively uniform excitation efficiency over a long axial range.The superior performance of the system was verified by phantom and in vivo experiments.Furthermore,the system was applied to the imaging of normal and trauma sites of volunteers,and the experimental results accurately revealed the morphological differences between the normal and traumatized skin of the epidermis and dermis.These results demonstrated that the E-DOF-PAM is a powerful tool for observing and understanding the pathophysiology of cutaneous wound healing. | Zhongwen CHENG Haigang MA Zhiyang WANG Sihua YANG | 2020 | Frontiers of Optoelectronics2020，13，4： | 3 |
| 20 | Analysis on clinically drug-used law for lung-intestine related diseases显示文摘OBJECTIVE:To analyze the application laws of clinical drugs by descriptive statistical method with the clinical literatures guided by 'lung being connected with large intestine' used as the object.METHODS:Retrievepubliclypublishedclinicalliteratures about 'lung being connected with large intestine'inrecent30years,establishthedatabaseofclinical literature,and study on the clinically drug-used lawsbydescriptivestatisticalanalyticmethod.RESULTS:The common high frequent drugs used for the lung-intestine related diseases were Gualou(Ructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus).For the different clinical syndrome types,in the commonly used drugs there were different characteristics,reflecting the principle of TCM syndrome differentiation treatment.CONCLUSION:The common high frequent drugs used for the lung-intestine related diseases are Gualou(Fructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus),which are commonly-used drugs for the lung-intestine related diseases,with differences for different syndrome types. | Luan Gao Jian Wang Fenggang Li Sihua Gao Yong Deng | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 3 |
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