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| 1 | Heterogeneous lamellar-edged Fe-Ni(OH)_(2)/Ni_(3)S_(2)nanoarray for efficient and stable seawater oxidation显示文摘Development of efficient non-precious catalysts for seawater electrolysis is of great significance but challenging due to the sluggish kinetics of oxygen evolution reaction(OER)and the impairment of chlorine electrochemistry at anode.Herein,we report a heterostructure of Ni_(3)S_(2)nanoarray with secondary Fe-Ni(OH)_(2)lamellar edges that exposes abundant active sites towards seawater oxidation.The resultant Fe-Ni(OH)_(2)/Ni_(3)S_(2)nanoarray works directly as a free-standing anodic electrode in alkaline artificial seawater.It only requires an overpotential of 269 mV to afford a current density of 10 mA·cm^(-2)and the Tafel slope is as low as 46 m V·dec^(-1).The 27-hour chronopotentiometry operated at high current density of 100 mA·cm^(-2)shows negligible deterioration,suggesting good stability of the Fe-Ni(OH)_(2)/Ni_(3)S_(2)@NF electrode.Faraday efficiency for oxygen evolution is up to〜95%,revealing decent selectivity of the catalyst in saline water.Such desirable catalytic performance could be benefitted from the introduction of Fe activator and the heterostructure that offers massive active and selective sites.The density functional theory(DFT)calculations indicate that the OER has lower theoretical overpotential than Cl_(2) evolution reaction in Fe sites,which is contrary to that of Ni sites.The experimental and theoretical study provides a strong support for the rational design of high-performance Fe-based electrodes for industrial seawater electrolysis. | Baihua Cui Zheng Hu Chang Liu Siliang Liu Fangshuai Chen Shi Hu Jinfeng Zhang Wei Zhou Yida Deng Zhenbo Qin Zhong Wu Yanan Chen Lifeng Cui Wenbin Hu | 2021 | Nano Research2021,14,4: | 7 |
| 2 | Repeated sending file delivery protocol in satellite networking communication显示文摘Satellite networking communications in navigation satellite system and space-based deep space exploration have the features of a long delay and high bit error rate (BER). Through analyzing the advantages and disadvantages of the Consultative Committee for the Space Data System (CCSDS) file delivery protocol (CFDP), a new improved repeated sending file delivery protocol (RSFDP) based on the adaptive repeated sending is put forward to build an efficient and reliable file transmission. According to the estimation of the BER of the transmission link, RSFDP repeatedly sends the lost protocol data units (PDUs) at the stage of the retransmission to improve the success rate and reduce time of the retransmission. Theoretical analyses and results of the Opnet simulation indicate that the performance of RSFDP has significant improvement gains over CFDP in the link with a long delay and high BER. The realizing results based on the space borne filed programmable gate array (FPGA) platform show the applicability of the proposed algorithm. | Yongqing Wang Jun Li Guang Chen Siliang Wu | 2012 | Journal of Systems Engineering and Electronics2012,23,6: | 3 |
| 3 | High Sensitivity Acquisition Algorithm for DSSS Signal with Data Modulation显示文摘In direct sequence spread spectrum communication both for satelliteto-ground and inter-satellite links, the system constrains due to radio frequency spectral occupation, channel data throughput and link performances in terms of data channel coding which might result in a signal structure where the symbol duration is shorter than the pseudo code period. This can generate some difficulties in the DSSS signal acquisition due to the polarity inversion caused by the data modulation. To eliminate the influence due to polarity inversion, this paper proposes a novel acquisition algorithm based on the simultaneous search of the code phase, data phase and Doppler frequency. In the proposed algorithm the data phase is predicted and the correlation period for the coherent integration can be set equal to the symbol duration. Then non-coherent accumulation over different symbol is implemented in order to enhance the acquisition algorithm sensitivity; the interval of non-coherent accumulation is the least common multiple between the symbol duration and the pseudo code period. The algorithm proposed can largely minimize the SNR loss caused by data polarity inversion and enhance acquisition performance without a noticeable increase in hardware complexity. Theoretical analysis, simulation and measured results verify the validity of the algorithm. | SHEN Yuyao WANG Yongqing CHEN Jingyao WU Siliang | 2015 | China Communications2015,12,4: | 2 |
| 4 | Protrusio acetabuli in ankylosing spondylitis patients with end-stage hip involvement显示文摘Protrusio acetabuli(PA)is_a complication of a wide spectrum_of pathological disorders involving the hip joint,[1] The underlying.causes can be infammatory[2,3] traumatic,genetic,metabolic,infectious,and idiopathic.Inflammatory causes lead todestruction and weakening of the bone surrounding the hip with resultant migration along the joint-reaction vector. | Hongchao Li Liang Zhang Siliang Man Tao Bian Mingxue Chen Hui Song Yixin Zhou | 2022 | Chinese Medical Journal2022,,10: | 1 |
| 5 | A Credit Card Fraud Model Prediction Method Based on Penalty Factor Optimization AWTadaboost显示文摘With the popularity of online payment, how to perform creditcard fraud detection more accurately has also become a hot issue. And withthe emergence of the adaptive boosting algorithm (Adaboost), credit cardfraud detection has started to use this method in large numbers, but thetraditional Adaboost is prone to overfitting in the presence of noisy samples.Therefore, in order to alleviate this phenomenon, this paper proposes a newidea: using the number of consecutive sample misclassifications to determinethe noisy samples, while constructing a penalty factor to reconstruct thesample weight assignment. Firstly, the theoretical analysis shows that thetraditional Adaboost method is overfitting in a noisy training set, which leadsto the degradation of classification accuracy. To this end, the penalty factorconstructed by the number of consecutive misclassifications of samples isused to reconstruct the sample weight assignment to prevent the classifierfrom over-focusing on noisy samples, and its reasonableness is demonstrated.Then, by comparing the penalty strength of the three different penalty factorsproposed in this paper, a more reasonable penalty factor is selected.Meanwhile, in order to make the constructed model more in line with theactual requirements on training time consumption, the Adaboost algorithmwith adaptive weight trimming (AWTAdaboost) is used in this paper, so thepenalty factor-based AWTAdaboost (PF_AWTAdaboost) is finally obtained.Finally, PF_AWTAdaboost is experimentally validated against other traditionalmachine learning algorithms on credit card fraud datasets and otherdatasets. The results show that the PF_AWTAdaboost method has betterperformance, including detection accuracy, model recall and robustness, thanother methods on the credit card fraud dataset. And the PF_AWTAdaboostmethod also shows excellent generalization performance on other datasets.From the experimental results, it is shown that the PF_AWTAdaboost algorithmhas better classification performance. | Wang Ning Siliang Chen Fu Qiang Haitao Tang Shen Jie | 2023 | Computers, Materials & Continua2023,,3: | 1 |
| 6 | Discovery of potential biomarkers for human atherosclerotic abdominal aortic aneurysm through untargeted metabolomics and transcriptomics显示文摘Abdominal aortic aneurysm(AAA)and atherosclerosis(AS)have considerable similarities in clinical risk factors and molecular pathogenesis.The aim of our study was to investigate the differences between AAA and AS from the perspective of metabolomics,and to explore the potential mechanisms of differential metabolites via integration analysis with transcriptomics.Plasma samples from 32 AAA and 32 AS patients were applied to characterize the metabolite profiles using untargeted liquid chromatography-mass spectrometry(LC-MS).A total of 18 remarkably different metabolites were identified,and a combination of seven metabolites could potentially serve as a biomarker to distinguish AAA and AS,with an area under the curve(AUC)of0.93.Subsequently,we analyzed both the metabolomics and transcriptomics data and found that seven metabolites,especially 2’-deoxy-D-ribose(2 d DR),were significantly correlated with differentially expressed genes.In conclusion,our study presents a comprehensive landscape of plasma metabolites in AAA and AS patients,and provides a research direction for pathogenetic mechanisms in atherosclerotic AAA. | Lei JI Siliang CHEN Guangchao GU Wei WANG Jinrui REN Fang XU Fangda LI Jianqiang WU Dan YANG Yuehong ZHENG | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021,22,9: | 1 |
| 7 | Use of support vector regression in structural optimization: Application to vehicle crashworthiness design显示文摘 | Ping Zhu Feng Pan Wei Chen Siliang Zhang | 2012 | Mathematics and Computers in Simulation2012,,: | 1 |
| 8 | Ethanol evolution rate:A new parameter to determine the feeding rate for the production of avermectins by Streptomyces avermitilis显示文摘 | Chen Jie Zhang Siliang Chu Ju | 2004 | Biotechnology Letters2004,26,: | 1 |
| 9 | Ultrafine Fe/Fe3C decorated on Fe-N_(x)-C as bifunctional oxygen electrocatalysts for efficient Zn-air batteries显示文摘Efficient bifunctional oxygen electrocatalysts for ORR and OER are fundamental to the development of high performance metal-air batteries.Herein,a facile cost-efficient two-step pyrolysis strategy for the fabrication of a bifunctional oxygen electrocatalyst has been proposed.The efficient non-preciousmetal-based electrocatalyst,Fe/Fe_(3)C@Fe-N_(x)-C consists of highly curved onion-like carbon shells that encapsulate Fe/Fe_(3)C nanoparticles,distributed on an extensively porous graphitic carbon aerogel.The obtained Fe/Fe_(3)C@Fe-N_(x)-C aerogel exhibited superb electrochemical activity,excellent durability,and high methanol tolerance.The experimental results indicated that the assembly of onion-like carbon shells with encapsulated Fe/Fe_(3)C yielded highly curved carbon surfaces with abundant Fe-Nxactive sites,a porous structure,and enhanced electrocatalytic activity towards ORR and OER,hence displaying promising potential for application as an air cathode in rechargeable Zn-air batteries.The constructed Zn-air battery possessed an exceptional peak power density of~147 mW cm^(-2),outstanding cycling stability(200 cycles,1 h per cycle),and a small voltage gap of 0.87 V.This study offers valuable insights regarding the construction of low-cost and highly active bifunctional oxygen electrocatalysts for efficient air batteries. | Lingbo Zong Xin Chen Siliang Liu Kaicai Fan Shuming Dou Jie Xu Xiaoxian Zhao Wenjun Zhang Yaowen Zhang Weicui Wu Fenghong Lu Lixiu Cui Xiaofei Jia Qi Zhang Yu Yang Jian Zhao Xia Li Yida Deng Yanan Chen Lei Wang | 2021 | Journal of Energy Chemistry2021,30,5: | 1 |
| 10 | Multi-point objective-oriented sequential sampling strategy for constrained robust design显示文摘 | Zhu Ping Zhang Siliang Chen Wei | 2015 | Engineering Optimization2015,47,3: | 1 |
| 11 | Realizing n-type CdSb with promising thermoelectric performance显示文摘Realizing high performance in both n-type and p-type materials is essential for designing efficient ther-moelectric devices.However,the doping bottleneck is often encountered,i.e.,only one type of conduction can be realized.As one example,p-type CdSb with high thermoelectric performance has been discovered for several decades,while its n-type counterpart has rarely been reported.In this work,the calculated band structure of CdSb demonstrates that the valley degeneracy is as large as ten for the conduction band,and it is only two for the valence band.Therefore,the n-type CdSb can potentially realize an ex-ceptional thermoelectric performance.Experimentally,the n-type conduction has been successfully real-ized by tuning the stoichiometry of CdSb.By further doping indium at the Cd site,an improved room-temperature electron concentration has been achieved.Band modeling predicts an optimal electron con-centration of∼2.0×1019 cm−3,which is higher than the current experimental values.Therefore,future optimization of the n-type CdSb should mainly focus on identifying practical approaches to optimize the electron concentration. | Peng Zhao Honghao Yao Shizhen Zhi Xiaojing Ma Zuoxu Wu Yijie Liu Xinyu Wang Li Yin Zongwei Zhang Shuaihang Hou Xiaodong Wang Siliang Chen Chen Chen Xi Lin Haoliang Liu Xingjun Liu Feng Cao Qian Zhang Jun Mao | 2023 | Journal of Materials Science & Technology2023,,13: | 0 |
| 12 | ANXA2 Facilitates Enterovirus 71 Infection by Interacting with 3D Polymerase and PI4KB to Assist the Assembly of Replication Organelles显示文摘Similar to that of other enteroviruses, the replication of enterovirus 71(EV71) occurs on rearranged membranous structures called replication organelles(ROs). Phosphatidylinositol 4-kinase Ⅲ(PI4KB), which is required by enteroviruses for RO formation, yields phosphatidylinositol-4-phosphate(PI4P) on ROs. PI4P then binds and induces conformational changes in the RNA-dependent RNA polymerase(Rd Rp) to modulate Rd Rp activity. Here, we targeted 3D polymerase, the core enzyme of EV71 ROs, and found that the host factor Annexin A2(ANXA2) can interact with 3 D polymerase and promote the replication of EV71. Then, an experiment showed that the annexin domain of ANXA2, which possesses membranebinding capacity, mediates the interaction of ANXA2 with EV71 3 D polymerase. Further research showed that ANXA2 is localized on ROs and interacts with PI4KB. Overexpression of ANXA2 stimulated the formation of PI4P, and the level of PI4P was decreased in ANXA2-knockout cells. Furthermore, ANXA2, PI4KB, and 3D were shown to be localized to the viral RNA replication site, where they form a higher-order protein complex, and the presence of ANXA2 promoted the PI4 KB-3D interaction. Altogether, our data provide new insight into the role of ANXA2 in facilitating formation of the EV71 RNA replication complex. | Qiuhan Zhang Siliang Li Ping Lei Zixian Li Feifei Chen Qi Chen Yulu Wang Jiami Gong Qi Tang Xinjin Liu Ke Lan Shuwen Wu | 2021 | Virologica Sinica2021,36,6: | 0 |
| 13 | Floret-like Fe-N_(x)nanoparticle-embedded porous carbon superstructures from a Fe-covalent triazine polymer boosting oxygen electroreduction显示文摘Fe–N_(x)nanoparticles-embedded porous carbons with a desirable superstructure have attracted immense attention as promising catalysts for electrochemical oxygen reduction reaction.Herein,we employed Fe-coordinated covalent triazine polymer for the fabrication of Fe–N_(x)nanoparticle-embedded porous carbon nanoflorets(Fe/N@CNFs)employing a hypersaline-confinement-conversion strategy.Presence of tailored N types within the covalent triazine polymer interwork in high proportions contributes to the generation of Fe/N coordination and subsequent Fe–N_(x)nanoparticles.Owing to the utilization of NaCl crystals,the resultant Fe/N@CNF-800 which was generated by pyrolysis at 800℃showed nanoflower structure and large specific surface area,which remarkably suppressed the agglomeration of high catalytic active sites.As expect,the Fe/N@CNF-800 exhibited unexpected oxygen reduction reaction catalytic performance with an ultrahigh half-wave potential(0.89 V vs.reversible hydrogen electrode),a dominant 4e–transfer approach and great cycle stability(>92%after 100000 s).As a demonstration,the Fe/N-PCNF-800-assembled zinc–air battery delivered a high open circuit voltage of 1.51 V,a maximum peak power density of 164 mW·cm^(-2),as well as eminent rate performance,surpassing those of commercial Pt/C.This contribution offers a valuable avenue to exploit efficient metal nanoparticles-based carbon catalysts towards energy-related electrocatalytic reactions and beyond. | Yong Zheng Mingjin Li Yongye Wang Niu Huang Wei Liu Shan Chen Xuepeng Ni Kunming Li Siwei Xiong Yi Shen Siliang Liu Baolong Zhou Niaz Ali Khan Liqun Ye Chao Zhang Tianxi Liu | 2023 | Frontiers of Chemical Science and Engineering2023,17,5: | 0 |
| 14 | Super-enhancer receives signals from the extracellular matrix to induce PD-L1-mediated immune evasion via integrin/ BRAF/TAK1/ERK/ETV4 signaling显示文摘Objective:PD-L1 and PD-L2 expression levels determine immune evasion and the therapeutic efficacy of immune checkpoint blockade.The factors that drive inducible PD-L1 expression have been extensively studied,but mechanisms that result in constitutive PD-L1 expression in cancer cells are largely unknown.Methods:DNA elements were deleted in cells by CRISPR/Cas9-mediated knockout.Protein function was inhibited by chemical inhibitors.Protein levels were examined by Western blot,mRNA levels were examined by real-time RT-PCR,and surface protein expression was determined by cellular immunofluorescence and flow cytometry.Immune evasion was examined by in vitro T cell-mediated killing.Results:We determined the core regions(chr9:5,496,378–5,499,663)of a previously identified PD-L1L2-super-enhancer(SE).Through systematic analysis,we found that the E26 transformation-specific(ETS)variant transcription factor(ETV4)bound to this core DNA region but not to DNA surrounding PD-L1L2SE.Genetic knockout of ETV4 dramatically reduced the expressions of both PD-L1 and PD-L2.ETV4 transcription was dependent on ERK activation,and BRAF/TAK1-induced ERK activation was dependent on extracellular signaling fromαvβ3 integrin,which profoundly affected ETV4 transcription and PD-L1/L2 expression.Genetic silencing or pharmacological inhibition of components of the PD-L1L2-SE-associated pathway rendered cancer cells susceptible to T cell-mediated killing.Conclusions:We identified a pathway originating from the extracellular matrix that signaled via integrin/BRAF/TAK1/ERK/ETV4 to PD-L1L2-SE to induce PD-L1-mediated immune evasion.These results provided new insights into PD-L1L2-SE activation and pathways associated with immune checkpoint regulation in cancer. | Panpan Ma Xinxin Jin Zhiwei Fan Zhou Wang Suhui Yue Changyue Wu Shiyin Chen Yuanyuan Wu Miaomiao Chen Donghua Gu Siliang Zhang Renfang Mao Yihui Fan | 2022 | Cancer Biology & Medicine2022,19,5: | 0 |