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| 1 | A Greedy Algorithm for Task Offloading in Mobile Edge Computing System显示文摘Mobile edge computing(MEC) is a novel technique that can reduce mobiles' computational burden by tasks offloading, which emerges as a promising paradigm to provide computing capabilities in close proximity to mobile users. In this paper, we will study the scenario where multiple mobiles upload tasks to a MEC server in a sing cell, and allocating the limited server resources and wireless channels between mobiles becomes a challenge. We formulate the optimization problem for the energy saved on mobiles with the tasks being dividable, and utilize a greedy choice to solve the problem. A Select Maximum Saved Energy First(SMSEF) algorithm is proposed to realize the solving process. We examined the saved energy at different number of nodes and channels, and the results show that the proposed scheme can effectively help mobiles to save energy in the MEC system. | Feng Wei Sixuan Chen Weixia Zou | 2018 | China Communications2018,15,11: | 28 |
| 2 | Easily manageable prognostic factors in 152 Chinese elderly acute myeloid leukemia patients:a single-center retrospective study显示文摘We retrospectively investigated the prognostic factors of acute myeloid leukemia(AML) in 152 Chinese patients with de novo AML who were older than 60 years of age and who received treatment at our hospital.Log-rank test showed that 6 parameters including older age,higher white blood cell(WBC) counts,lactate dehydrogenase(LDH)and bone marrow(BM) blasts at diagnosis,unfavorable risk cytogenetics,and non-mutated CEBPα were significant adverse prognostic factors of overall survival(OS) for elderly AML patients(P = 0.0013,0.0358,0.0132,0.0242,0.0236 and 0.0130,respectively).Moreover,older age and higher LDH were significant adverse predictors for relapse-free survival(RFS)(P = 0.0447 and 0.0470,respectively).Univariate analysis revealed similar results for OS to those of the log-rank test and only higher LDH at diagnosis was a significant adverse predictor for RFS(P = 0.028,HR:1.979,95%CI:1.075-3.644).In multivariate analysis,we identified 2 trends towards independent prognostic factors for OS,including BM blasts at diagnosis(P = 0.057,HR:1.676,95%CI:0.984-2.854)and mutation status of CEBPα(P = 0.064,HR:4.173,95%CI:0.918-18.966).Our data indicated that older age,gender and a previous history of hematologic diseases resulted in lower complete remission rate(P = 0.012,0.051 and 0.086,respectively).We further developed an easy scoring system for predicting prognosis and response to induction therapy in older AML patients.Patients who had lower scores showed significantly longer OS and RFS(P = 0.0006 and 0.1001,respectively) and higher CR rate(P = 0.014).Our research is limited by its retrospective nature and the results from our study need to be further validated by prospective randomized clinical trials. | Jiadai Xu Tingmei Chen Yun Liu Huayuan Zhu Wei Wu WenYi Shen Bei Xu Sixuan Qian Jianyong Li Peng Liu | 2014 | The Journal of Biomedical Research2014,28,5: | 7 |
| 3 | Water level variation characteristics under the impacts of extreme drought and the operation of the Three Gorges Dam显示文摘Under the influence of a climate of extreme drought and the Three Gorges Dam (TGD) operation, the water levels in the middle and lower reaches of the Yangtze River in 2006 and 2011 changed significantly compared with those in the extreme drought years of 1978 and 1986. To quantitatively analyze the characteristics of water level variations in 2006 and 2011, a new calculation method was proposed, and the daily water level and discharge from 1955-2016 were collected in this study. The findings are as follows: in 2006 and 2011, the water level in the dry season significantly increased, but that in the flood season obviously decreased compared with the levels in 1978 and 1986. Here, we described this phenomenon as “no low-water-level in dry season, no high-water-level in flood season”. Based on the calculation method, the contributions of climate variability and the Three Gorges Dam operation to water level variations in the middle and lower reaches of the Yangtze River were calculated, and the contributions indicated that climate variability was the main reason for the phenomenon of “no low-water-level in diy season, no high-water-level in flood season” instead of flood peak reduction in the flood season and drought runoff implementation in the dry season, which are both induced by TGD. | Yuanfang CHAI Yitian LI Yunping YANG Sixuan LI Wei ZHANG Jinqiu REN Haibin XIONG | 2019 | Frontiers of Earth Science2019,13,3: | 3 |
| 4 | Self-catalyzed formation of strongly interconnected multiphase molybdenum-based composites for efficient hydrogen evolution显示文摘Molybdenum carbide(MoxC)with variable phase structure possesses flexible hydrogen-binding energy(HBE),which is a promising hydrogen evolution reaction(HER)catalyst.Herein,a hybrid multiphase MoxC freestanding film coupled with Co3Mo(CM/MoxC@NC)is synthesized through the electrospinning method supplemented by the heteroatom incorporation.CM/MoxC@NC surpasses its pure phase counterparts and exhibits remarkable catalytic activity at 114mV to deliver a current density of 10mA cm^(−2) in acid,which is among the first-rate level performance reported for MoxC-based catalysts.The subsequent ex situ and in situ characterizations reveal a phase transition mechanism based on self-catalysis that CoOx depletes the coordinated C ofα-MoC via the interaction,which realizes the assembly of weak HBEα-MoC and strong HBEβ-Mo2C,and the enhanced utilization of active materials as well.The multiple structures with optimal HBE are in favor of the stepwise reactions of HER,as the study of the correlation between HBE and phase structure revealed.This study discloses the underlying phase transition mechanism and highlights the HBE–structure relationship that should be considered for catalyst design. | Jiani Chen Haijuan Zhang Jie Yu Daqin Guan Sixuan She Wei Zhou Zongping Shao | 2022 | Carbon Energy2022,4,1: | 2 |
| 5 | Holocene environmental changes in Bangong Co basin (Western Tibet). Part 2: The pollen record显示文摘 | E. Van Campo P. Cour Hang Sixuan | 1996 | Palaeogeography, Palaeoclimatology, Palaeoecology1996,,1: | 1 |
| 6 | Land institution of China:overall framework,structural evolution,and regulation intensity显示文摘China's land institution can be defined broadly or narrowly. By examining the broad definition of the land institution, we found that there were prerequisite, complementary, and substitutional relationships among the various systems. These relationships were verified through discussion of the structural evolution of each system. Based on these relationships, three methods for quantification were used to measure the regulation intensity and intra-provincial differences in each system among 31 provinces, municipalities, and autonomous regions in China in 2014. The statistics analysis shows that provinces used to pursue outstanding performances in land institution but few provinces could outperform the other provinces in all types of systems. The statistics results also indicate that the provinces which executed land institution earlier often hold significant advantages in institutional innovations but it is still not clear whether they can maintain the advantages. This study recommends that the Chinese government should improve the overall framework of regional land institution based on land systems' relationships and evolutionary patterns. Furthermore, the government should optimize the spatial distribution of regional land institution based on the intra-provincial differences in land-regulation intensity. | Xinhua Zhu Sixuan Lu | 2018 | Chinese Journal of Population,Resources and Environment2018,16,1: | 1 |
| 7 | Detection of BCR-ABL fusion proteins in patients with leukemia using a cyto- metric bead array显示文摘 | Wu Yujie Zhu Yu Qian Sixuan | 2012 | Leuk Lymphoma2012,53,3: | 1 |
| 8 | Zircon classification from cathodoluminescence images using deep learning显示文摘Zircon is a widely-used heavy mineral in geochronological and geochemical research because it can extract important information to understand the history and genesis of rocks. Zircon has various types,and an accurate examination of zircon type is a prerequisite procedure before further analysis.Cathodoluminescence(CL) imaging is one of the most reliable ways to classify zircons. However, current CL image examination is conducted by manual work, which is time-consuming, bias-prone, and requires expertise. An automated and bias-free method for zircon classification is absent but necessary. To this end, deep convolutional neural networks(DCNNs) and transfer learning are applied in this study to classify the common types of zircons, i.e., igneous, metamorphic, and hydrothermal zircons. An atlas with over 4000 CL images of these three types of zircons is created, and three DCNNs are trained using these images. The results of this study indicate that the DCNNs can distinguish hydrothermal zircons from other zircons, as indicated by the highest accuracy of 100%. Although similar textures in igneous and metamorphic zircons pose great challenges for zircon classification, the DCNNs successfully classify 95% igneous and 92% metamorphic zircons. This study demonstrates the high accuracy of DCNNs in zircon classification and presents the great potentiality of deep learning techniques in numerous geoscientific disciplines. | Dongyu Zheng Sixuan Wu Chao Ma Lu Xiang Li Hou Anqing Chen Mingcai Hou | 2022 | Geoscience Frontiers2022,13,6: | 0 |
| 9 | Research Through Unearthed Epitaphs:The Tuyuhun People’s Sinicization During the Northern Dynasties显示文摘In the middle and late Northern Wei Dynasty,Tuyuhun people gradually entered political field of Central Plains Dynasty,and cultural merging came with the interaction of the crowd.Although Tuyuhun Kingdom located in the northwestern area,Tuyuhun people’s epitaphs whose unearthed places were known so far were all found in the Central Plains,which shows that Tuyuhun was closely linked with the Central Plains Dynasty in politics and culture.Taking epitaph of Tuyuhun Ji as the center,this thesis analyzes the political and cultural phenomenon reflected in the epitaph,on the basis of reorganizing his genealogy and official career.At the same time,combining with unearthed epigraphs of other Tuyuhun people in the Northern Dynasties,the thesis analyzes the sinicization elements in the cognitive identity of tomb owners and their images reflected in inscriptions,and further discusses the transformation of the concepts of national,ethnic,and cultural identity of Tuyuhun people who lived in the Central Plains. | PAN Sixuan | 2022 | Psychology Research2022,12,3: | 0 |
| 10 | The combination therapy of imatinib and dasatinib achieves long-term molecular response in two imatinib-resistant and dasatinibintolerant patients with advanced chronic myeloid leukemia显示文摘For patients with chronic myeloid leukemia(CML) failing imatinib therapy,second-generation tyrosine kinase inhibitors(TKIs) are recommended.Here,we describe two patients with advanced CML who failed imatinib therapy and did not tolerate the recommended dose of dasatinib,but then achieved a major molecular response with the combination of imatinib and dasatinib with no significant extramedullar/ toxicity.Our observations suggest that combination of TKIs may provide an additive/synergistic antileukemic effect. | Yu Zhu Liangqin Pan Ming Hong Weixing Liu Chun Qiao Jianyong Li Sixuan Qian | 2016 | The Journal of Biomedical Research2016,30,6: | 0 |
| 11 | Modeling and simulation as a service architecture for deploying resources in the Cloud显示文摘In recent years,Cloud Computing has become popular to facilitate the use of Modeling and Simulation(M&S)resources.Nevertheless,there are still various issues to solve,including the structure constrain of chosen web service frameworks,the sharing of varied resources in the Cloud,and the difficulties in reproducing experiments.We show a new architecture based on Cloud Computing and new modeling methods to deal with these issues.This layered architecture,called Cloud Architecture for Modeling and Simulation as a Service(CAMSaaS),simplifies the deployment of M&S resources as services in the Cloud.CAMSaaS supports hierarchical resource services,experimental frameworks,scalable infrastructure and makes everything as a service.We deploy varied M&S resources as services in the Cloud,and build a Modeling and Simulation as a Service(MSaaS)middleware called CloudRISE to manage a variety of M&S resources.We also use the experimental framework concept to simplify the management of experiment environments.We present a case study for crowd evacuation application using the architecture. | Sixuan Wang Gabriel Wainer | 2016 | International Journal of Modeling, Simulation, and Scientific Computing2016,7,1: | 0 |
| 12 | Multivariate statistical and bioinformatic analyses for the seasonal variations of actinobacterial community structures in a drinking water reservoir显示文摘Actinobacterial community is a conspicuous part of aquatic ecosystems and displays an important role in the case of biogeochemical cycle,but little is known about the seasonal variation of actinobacterial community in reservoir ecological environment.In this study,the high-throughput techniques were used to investigate the structure of the aquatic actinobacterial community and its inducing water quality parameters in different seasons.The results showed that the highest diversity and abundance of actinobacterial community occurred in winter,with Sporichthya(45.42%)being the most abundant genus and Rhodococcus sp.(29.32%)being the most abundant species.Network analysis and correlation analysis suggested that in autumn the dynamics of actinobacterial community were infuenced by more factors and Nocardioides sp.SX2R5S2 was the potential keystone species which was negatively correlated with temperature(R=-0.72,P<0.05).Changes in environmental factors could significantly affect the changes in actinobacterial community,and the dynamics of temperature,dissolved oxygen(DO),and turbidity are potential conspicuous factors infuencing seasonal actinobacterial community trends.The partial least squares path modeling further elucidated that the combined effects of DO and temperature not only in the diversity of actinobacterial community but also in other water qualities,while the physiochemical parameters(path coefficient=1.571,P<0.05)was strong environmental factors in natural mixture period.These results strengthen our understanding of the dynamics and structures of actinobacterial community in the drinking water reservoirs and provide scientific guidance for further water quality management and protection in water sources. | Haihan Zhang Sixuan Pan BenMa Tinglin Huang Dmitry B.Kosolapov Manli Ma Xiang Liu Huan Liu Xiaoyan Liu | 2024 | Journal of Environmental Sciences2024,,3: | 0 |
| 13 | Application of Internet of Things Technology in Enterprise Marketing Management Innovation显示文摘Marketing is a very important part of an enterprise.A rational and scientific marketing management can not only reduce the cost of enterprise sales,but also greatly improve the competitiveness of enterprises.The purpose of this paper is to study the innovative application of enterprise marketing management based on the Internet of Things technology.The most suitable competitive strategy of the company is put forward as the centralized strategy.And put forward the clear strategy implementation details,introduced the current situation and history of the Internet of things,and combined with the development status,put forward the necessity of the enterprise marketing management system based on the Internet of things technology.It provides a guiding direction for most enterprises to formulate business competition strategies.The theory and technology used in system development are introduced,including C/S structure,B/S structure,NET Framework,AJAX technology,and database technology.The system design process is introduced in detail,including business process design,architecture design and system operation planning.The functional test cases and test environment for system testing are introduced.The results show that when 200 people log in at the same time,the response time is 1.5 s. | Huan Xu Sixuan Chen | 2022 | Journal on Internet of Things2022,4,2: | 0 |
| 14 | Focal-type,but not Diffuse-type,Amyloid Beta Plaques are Correlated with Alzheimer’s Neuropathology,Cognitive Dysfunction,and Neuroinflammation in the Human Hippocampus显示文摘Amyloid beta(Aβ)plaques are one of the hallmarks of Alzheimer’s disease(AD).However,currently available anti-amyloid therapies fail to show effectiveness in the treatment of AD in humans.It has been found that there are different types of Aβplaque(diffuse and focal types)in the postmortem human brain.In this study,we aimed to investigate the correlations among different types of Aβplaque and AD-related neuropathological and cognitive changes based on a postmortem human brain bank in China.The results indicated that focal plaques,but not diffuse plaques,significantly increased with age in the human hippocampus.We also found that the number of focal plaques was positively correlated with the severity of AD-related neuropathological changes(measured by the“ABC”scoring system)and cognitive decline(measured by the Everyday Cognitive Insider Questionnaire).Furthermore,most of the focal plaques were co-localized with neuritic plaques(identified by Bielschowsky silver staining)and accompanied by microglial and other inflammatory cells.Our findings suggest the potential of using focal-type but not general Aβplaques as biomarkers for the neuropathological evaluation of AD. | Fan Liu Jianru Sun Xue Wang Sixuan Jin Fengrun Sun Tao Wang Bo Yuan Wenying Qiu Chao Ma | 2022 | Neuroscience Bulletin2022,38,10: | 0 |
| 15 | Combination of S…N and S…Cl Noncovalently Conformational Locks for Constructing High-Planarity and Low-Cost Nonfused-Ring Electron Acceptors显示文摘Comprehensive Summary By employing thiazole and 4-chlorothiazole as the A′units,two A-D-A′-D-A type nonfused-ring electron acceptors(NFREAs)Tz-H and Tz-Cl were designed and synthesized.Replacing thiazole in Tz-H with 4-chlorothiazole can not only remarkably shorten the synthetic route through C—H direct arylation but also enhance molecular planarity with the simultaneous incorporation of S…N and S…Cl noncovalently conformational locks(NoCLs).The photovoltaic devices based on PM6:Tz-Cl exhibited a power conversion efficiency as high as 11.10%,much higher than that of PM6:Tz-H(6.41%),mainly due to more efficient exciton dissociation,better and more balanced carrier mobility,less charge recombination,and more favorable morphology.These findings demonstrate the great potential of NoCLs in achieving low-cost and high-performance NFREAs. | Ziyang Han Congqi Li Xiaobin Gu Xiao Han Sixuan Wang Yanan Wei Jinhua Gao Zhixiang Wei Yunhao Cai Xin Zhang Hui Huang | 2023 | Chinese Journal of Chemistry2023,41,15: | 0 |
| 16 | Chromosome-level genome assembly of Salvia miltiorrhiza with orange roots uncovers the role of Sm2OGD3 in catalyzing 15,16-dehydrogenation of tanshinones显示文摘Salvia miltiorrhiza is well known for its clinical practice in treating heart and cardiovascular diseases.Its roots,used for traditional Chinese medicine materials,are usually brick-red due to accumulation of red pigments,such as tanshinone IIA and tanshinone I.Here we report a S.miltiorrhiza line(shh)with orange roots.Compared with the red roots of normal S.miltiorrhiza plants,the contents of tanshinones with a single bond at C-15,16 were increased,whereas those with a double bond at C-15,16 were significantly decreased in shh.We assembled a high-quality chromosome-level genome of shh.Phylogenomic analysis showed that the relationship between two S.miltiorrhiza lines with red roots was closer than the relationship with shh.It indicates that shh could not be the mutant of an extant S.miltiorrhiza line with red roots.Comparative genomic and transcriptomic analyses showed that a 1.0 kb DNA fragment was deleted in shh Sm2OGD3m.Complementation assay showed that overexpression of intact Sm2OGD3 in shh hairy roots recovered furan D-ring tanshinone accumulation.Consistently,in vitro protein assay showed that Sm2OGD3 catalyzed the conversion of cyptotanshinone,15,16-dihydrotanshinone I and 1,2,15,16-tetrahydrotanshinone I into tanshinone IIA,tanshinone I and 1,2-dihydrotanshinone I,respectively.Thus,Sm2OGD3 functions as tanshinone 15,16-dehydrogenase and is a key enzyme in tanshinone biosynthesis.The results provide novel insights into the metabolic network of medicinally important tanshinone compounds. | Xian Pan Yujie Chang Caili Li Xiaoxiao Qiu Xinyun Cui Fanqi Meng Sixuan Zhang Xian’en Li Shanfa Lu | 2023 | Horticulture Research2023,10,6: | 0 |