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| 1 | The Tea Tree Genome Provides Insights into Tea Flavor and Independent Evolution of Caffeine Biosynthesis显示文摘茶是世界有巨大的经济、药用、文化的重要性的最旧、很流行的包含咖啡因的饮料。这里,我们在场第一个高质量的核苷酸序列充满重复(80.9%) ,栽培的茶树山茶 sinensis 的 3.02-Gb 染色体。我们证明茶树的一种非常地大的染色体尺寸从一些 LTR retrotransposon 家庭的慢、稳定、长期的扩大被结果。除了一个最近的整个染色体的复制事件,基因的系特定的扩大把新陈代谢的生合成与 flavonoid 联系了被发现,它提高 catechin 生产,萜烯酶激活,和应力公差,为茶风味和改编的重要特征。我们相对可可子和咖啡表明一个独立人士和茶咖啡因合成小径的快速的进化。在 25 山茶种类之中的比较研究表明那更高的表情大多数 flavonoid- 和咖啡因铺平 -- 然而并非 theanine 相关的基因贡献 catechins 和咖啡因的增加的生产并且因此提高处理茶的适用性和茶质量。这些新奇调查结果为进一步的 metabolomic 和典型生合成小径的功能的 genomic 精炼铺平道路并且将帮助开发将最后满足并且吸引世界范围的更多的茶喝酒者的茶风味的一个更多样化的集合。 | En-Hua Xia Hai-Bin Zhang Jun Sheng Kui Li Qun-Jie Zhang Changhoon Kim Yun Zhang Yuan Liu Ting Zhu Wei Li Hui Huang Yan Tong Hong Nan Cong Shi Chao Shi Jian-Jun Jiang Shu-Yan Mao Jun-Ying Jiao Dan Zhang Yuan Zhao You-Jie Zhao Li-Ping Zhang Yun-Long Liu Ben-Ying Liu Yue Yu Sheng-Fu Shao De-Jiang Ni Evan E. Eichler Li-Zhi Gao | 2017 | Molecular Plant2017，10，6： | 113 |
| 2 | Paeoniflorin suppresses TGF-β mediated epithelial- mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway显示文摘 | Yu JI Yan-nong DOU Qian-wen ZHAO Ji-zhou ZHANG Yan YANG Ting WANG Yu-feng XIA Yue DAI Zhi-feng WEI | 2016 | Acta Pharmacologica Sinica2016，37，6： | 48 |
| 3 | Gain self-scheduled H_∞ control for morphing aircraft in the wing transition process based on an LPV model显示文摘This article investigates gain self-scheduled H 1 robust control system design for a tailless fold- ing-wing morphing aircraft in the wing shape varying process. During the wing morphing phase, the aircraft's dynamic response will be governed by time-varying aerodynamic forces and moments. Nonlinear dynamic equations of the morphing aircraft are linearized by using Jacobian linearization approach, and a linear parameter varying (LPV) model of the morphing aircraft in wing folding is obtained. A multi-loop controller for the morphing aircraft is formulated to guarantee stability for the wing shape transition process. The proposed controller uses a set of inner-loop gains to provide stability using classical techniques, whereas a gain self-scheduled H 1 outer-loop controller is devised to guarantee a specific level of robust stability and performance for the time-varying dynamics. The closed-loop simulations show that speed and altitude vary slightly during the whole wing folding process, and they converge rapidly after the process ends. This proves that the gain self-scheduled H 1 robust controller can guarantee a satisfactory dynamic performance for the morphing aircraft during the whole wing shape transition process. Finally, the flight control system's robustness for the wing folding process is verified according to uncertainties of the aerodynamic parameters in the nonlinear model. | Yue Ting Wang Lixin Ai Junqiang | 2013 | Chinese Journal of Aeronautics2013，26，4： | 34 |
| 4 | The Role of Fibrocyte in the Pathogenesis of Silicosis显示文摘Exposure to free silica induces silicosis and myofibroblasts are regarded as primary effector cells.Fibrocytes can differentiate into myofibroblast.Therefore,the present study was designed to investigate whether | LI Juan YAO Wu HOU Jian Yong ZHANG Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao YU Xing Hao ZHANG Jian Hui QU Ya Qian HAO Chang Fu | 2018 | Biomedical and Environmental Sciences2018，31，4： | 20 |
| 5 | Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs.3 doses in young women显示文摘A new HPV-16/18 bivalent vaccine expressed by the Escherichia coli has been proven to be efficacious in adult women.A randomized,immunogenicity noninferiority study of this candidate vaccine was conducted in December 2015 in China.Girls aged 9–14 years were randomized to receive 2 doses at months 0 and 6(n=301)or 3 doses at months 0,1 and 6(n=304).Girls aged 15–17 years(n=149)and women aged 18–26 years(n=225)received 3 doses.The objectives included noninferiority analysis of the IgG geometric mean concentration(GMC)ratio(95%CI,lower bound>0.5)to HPV-16 and HPV-18 at month 7 in girls compared with women.In the per-protocol set,the GMC ratio of IgG was noninferior for girls aged 9–17 years receiving 3 doses compared with women(1.76(95%CI,1.56,1.99)for HPV-16 and 1.93(95%CI,1.69,2.21)for HPV-18)and noninferior for girls aged 9–14 years receiving 2 doses compared with women(1.45(95%CI,1.25,1.62)for HPV-16 and 1.17(95%CI,1.02,1.33)for HPV-18).Noninferiority was also demonstrated for neutralizing antibodies.The immunogenicity of the HPV vaccine in girls receiving 3 or 2 doses was noninferior compared with that in young adult women. | Yue-Mei Hu Meng Guo Chang-Gui Li Kai Chu Wen-Gang He Jing Zhang Jian-Xiang Gu Juan Li Hui Zhao Xiang-Hong Wu Bi-Zhen Lin Zhi-Jie Lin Xing-Mei Yao Ya-Fei Li Fei-Xue Wei Yue Huang Ying-Ying Su Feng-Cai Zhu Shou-Jie Huang Hui-Rong Pan Ting Wu Jun Zhang Ning-Shao Xia | 2020 | Science China(Life Sciences)2020，63，4： | 19 |
| 6 | Diagnosis and endovascular treatment of spontaneous direct carotid-cavernous fistula显示文摘背景自发的直接颈动脉多孔的管( CCF )是相对稀罕的,很少报告在纸是报导临床的特征的这的 literature.The 目的被发现了,成像调查结果和为有自发的直接 CCF 的九个病人的临床的数据在2003年5月和2007年11月和 endovascular treatment.Sudden neuro-ophthalmologic 的结果之间招收的有我们回顾地分析了的自发的直接 CCF.Methods 的病人的 endovascular | YU Jia-sheng LEI Ting CHEN Jin-cao HE Yue CHEN Jian LI Ling | 2008 | Chinese Medical Journal2008，，16： | 12 |
| 7 | The Effects of Demographic Features on Differences in Sensitivity between PCL-C and SCL-90 Scores in a Follow-up Study in Secondary School Students in the Wenchuan Earthquake Region显示文摘Objective To analyze the sensitivity of effect factors between the PCL‐C and the SCL‐90,to provide evidence for social psychological crisis screening and post‐trauma interventions.Methods We administered the PCL‐C and SCL‐90 to screen for PTSD and other psychological problems among students who survived the disaster and continued their school studies.The surveys were carried out 3,6,9,and 12 months after the earthquake.A bivariate 2‐level logistic model was used to explore the different levels of sensitivity among students.The factors influencing the relationships between PTSD and depression,and between PTSD and anxiety were examined.Results We analyzed data from 1 677 students,revealing that female students in higher grades were more likely to exhibit symptoms of depression,rather than PTSD,compared with the control group (males in lower grades),and the difference was significant (P<0.05).In contrast,ethnic minorities were more likely to exhibit PTSD symptoms compared to the others.In addition,female students were more likely to exhibit symptoms of anxiety than PTSD.Other effects that did not reach statistical significance were suggested to have a similar influence on PTSD,depression,and anxiety.Conclusion After a natural disaster,specific aspects of depression and anxiety should be examined,avoiding an overemphasis on PTSD in social psychological crisis interventions. | HOU Feng Su LI Ting LI Juan HU Xiao Qin LIU Zhi Yue YUAN Ping | 2011 | Biomedical and Environmental Sciences2011，24，6： | 11 |
| 8 | Carnosic acid enhances the anti-lung cancer effect of cisplatin by inhibiting myeloid-derived suppressor cells显示文摘Cisplatin and other platinum-based drugs are used frequently for treatment of lung cancer. However, their clinical performance are usually limited by drug resistance or toxic effects. Carnosic acid, a polyphenolic diterpene isolated from Rosemary(Rosemarinus officinalis), has been reported to have several pharmacological and biological activities. In the present study, the combination effect of cisplatin plus carnosic acid on mouse LLC(Lewis lung cancer) xenografts and possible underlying mechanism of action were examined. LLC-bearing mice were treated with intraperitoneal injection with cisplatin, oral gavage with carnosic acid, or combination with cisplatin and carnosic acid, respectively. Combination of carnosic acid and cisplatin yielded significantly better anti-growth and pro-apoptotic effects on LLC xenografts than drugs alone. Mechanistic study showed that carnosic acid treatment boosted the function of CD8^+T cells as evidenced by higher IFN-γ secretion and higher expression of FasL, perforin as well as granzyme B. In the meantime, the proportion of MDSC(myeloid-derived suppressor cells) in tumor tissues were reduced by carnosic acid treatment and the mRNA levels of iNOS2, Arg-1, and MMP9, which are the functional markers for MDSC, were reduced. In conclusion, our study proved that the functional suppression of MDSC by carnosic acid promoted the lethality of CD8^+T cells, which contributed to the enhancement of anti-lung cancer effect of cisplatin. | LIU Wen WU Tian-Cong HONG Dong-Mei HU Yue FAN Ting GUO Wen-Jie XU Qiang | 2018 | Chinese Journal of Natural Medicines2018，16，12： | 11 |
| 9 | Norisoboldine alleviates joint destruction in rats with adjuvant-induced arthritis by reducing RANKL, IL-6, PGE2, and MMP-13 expression显示文摘 | Zhi-feng WEI Xiao-lan JIAO Ting WANG Qian LU Yu-feng XIA Zheng-tao WANG Qing-long GUO Gui-xin CHOU Yue DAI | 2013 | Acta Pharmacologica Sinica2013，34，3： | 10 |
| 10 | Rheum emodin inhibits enterovirus 71 viral replication and affects the host cell cycle environment显示文摘人的 enterovirus (EV71 ) 71 是在亚洲的手,脚,和嘴疾病(HFMD ) 的最近的大规模爆发的主要原因的代理人。当前,没有为 HFMD 的预防和处理可得到的药。在这研究,我们比较了传统地为流行疾病的处理和预防被使用了的分别地,从中国植物汉语大黄, Artemisia carvifolia 和距骨提取的三自然混合物,感冒 emodin, artemisinin 和 astragaloside 的 anti-EV71 活动。人的肺成纤维细胞房间线 MRC5 与 EV71 感染嘲笑或感染,并且与药对待。这些药的 cytotoxicity 与 MTT 试金被检测。象房间死亡和压缩原子核那样的 cytopathic 效果词法上被观察。为 EV71 染色体复制要求的编码 VP1 顺序是有 qRT-PCR 的 assayed。病毒的蛋白质表示与西方的弄污被分析。病毒的 TCID50 决心评估 EV71 毒力。propidium 碘化物染色的流动 cytometry 分析被执行分析 MRC5 房间的房间周期分发。感冒 emodin (29.6 mol/L ) 有效地保护了 MRC5 房间免受导致 EV71 的 cytopathic 效果的伤害,它源于禁止病毒的复制:感冒 emodin 处理减少了由 5.34 褶层,由不到 30 褶层的病毒的蛋白质表示和由 0.33107 褶层的 EV71 毒力的病毒的 genomic 层次。病毒的毒力上的感冒 emodin 的抑制是比它 genomic 层次和病毒的蛋白质表示上的效果强壮得多的事实建议感冒 emodin 禁止了病毒的成熟。而且,感冒 emodin 处理显著地减少了在 S 的房间周期拘捕在 MRC5 房间分阶段执行,它被 EV71 感染导致并且赞成了病毒的复制。相反,既不 astragaloside (50 mol/L ) 也不 artemisinin (50 mol/L ) 显示出类似的 anti-EV71 活动。在测试的三自然混合物之中,感冒 emodin 有效地压制了 EV71 病毒的复制,因此是候选人 anti-HFMD 药。 | Ting ZHONG Li-ying ZHANG Zeng-yan WANG Yue WANG Feng-mei SONG Ya-hong ZHANG Jing-hua YU | 2017 | Acta Pharmacologica Sinica2017，38，3： | 9 |
| 11 | Psychophysiological Effects of Bamboo Plants on Adults显示文摘The present study was conducted to clarify the psychophysiological relaxation effects of viewing bamboo on university students. Forty healthy Chinese participants enrolled in this study to clarify the psychophysiological relaxation effects of viewing bamboo. The effects of visual stimulation using a pot both with and without a bamboo were recorded by measuring the student's blood pressure, EEG and STAI. We observed that viewing bamboo plants resulted in significantly lower systolic(female, P < 0.001; male, P < 0.001; P < 0.05) and diastolic(female,P < 0.001; male, P < 0.001; P < 0.05) blood pressures, but no changes in the pulse rate(female, P = 0.09; male, P = 0.07; P > 0.05) were observed. The results of the EEG analysis indicated brainwave variation(all P < 0.05) and lower anxiety scores(P < 0.01) after 3 min of viewing bamboo compared with the control. These findings indicate that visual stimulation with bamboo plants induced psychophysiological relaxation effects on adults. | Ahmad Hassan CHEN Qi Bing JIANG Tao LYU Bing Yang LI Nian LI Shu SHANGGUAN Zi Yue LI Yun Ting JUN Zhou Li LUO Qian CHEN Xin Yi WANG Yi Yan ZENG Cheng Cheng YANG Jun Muhammad Sohaib Tahir | 2017 | Biomedical and Environmental Sciences2017，30，11： | 8 |
| 12 | Polycyclic aromatic hydrocarbon concentrations, compositions, sources, and associated carcinogenic risks to humans in farmland soils and riverine sediments from Guiyu, China显示文摘The concentrations of 16 priority polycyclic aromatic hydrocarbons(PAHs) were measured in 23 farmland soil samples and 10 riverine sediment samples from Guiyu, China, and the carcinogenic risks associated with PAHs in the samples were evaluated. Guiyu is the largest electronic waste(EW) dismantling area globally, and has been well known for the primitive and crude manner in which EWs are disposed, such as by open burning and roasting. The total PAH concentrations were 56–567 ng/g in the soils and 181–3034 ng/g in the sediments.The Shanglian and Huamei districts were found to be more contaminated with PAHs than the north of Guiyu. The soils were relatively weakly contaminated but the sediments were more contaminated, and sediments in some river sections might cause carcinogenic risks to the groundwater system. The PAHs in the soils were derived from combustion sources,but the PAHs in the sediments were derived from both combustion and petroleum sources. | Pengjun Xu Bu Tao Zhiqiang Ye Hu Zhao Yue Ren Ting Zhang Yeru Huang Jiping Chen | 2016 | Journal of Environmental Sciences2016，28，10： | 8 |
| 13 | Rat model of cholelithiasis with human gallstones implanted in cholestasis-induced virtual gallbladder显示文摘AIM:To facilitate translational research on cholelithiasis,we have developed a rat model of human gallstones by exploiting the unique biliopancreatic features of this species.METHODS:Under anesthesia,16 adult rats of equal genders underwent two times of abdominal surgery.First,their common bile duct(CBD)was ligated to cause cholestasis by total biliary obstruction(TBO).On day 0,1,3,7,14,21 and 28 after TBO,magnetic resonance imaging(MRI)was conducted to monitor the dilatation of the CBD,and blood was sampled to analyze total serum bilirubin(TSB).Secondly,on day 30,the abdomen was re-opened and gallstone(s)collected from human patients were implanted in the dilated CBD asa virtual gallbladder(VGB),which was closed by suture ligation.This rat cholelithiasis model was examined by MRI,clinical observation,microcholangiography and histology.RESULTS:All rats survived two laparotomies.After ligation,the CBD was dilated to a stable size of 4 to30 mm in diameter on day 21-28,which became a VGB.The rats initially showed signs of jaundice that diminished over time,which paralleled with the evolving TSB levels from 0.6±0.3 mg/d L before ligation,through a peak of 10.9±1.9 mg/dL on day 14,until a nearly normalized value after day 28.The dilated CBD with thickened wall allowed an incision for implantation of human gallstones of 1-10 mm in diameter.The rat cholelithiasis was proven by in vivo MRI and postmortem microcholangiography and histomorphology.CONCLUSION:A rat model cholelithiasis with human gallstones has been established,which proves feasible,safe,reliable,nontoxic and cost-effective.Given the gallstones of human origin,applications of this model may be of help in translational research such as optical detection and lysis of gallstones by systemic drug administration. | Marlein Miranda Cona Yewei Liu Ting Yin Yuanbo Feng Feng Chen Stefaan Mulier Yue Li Jian Zhang Raymond Oyen Yicheng Ni | 2016 | World Journal of Methodology2016，6，2： | 7 |
| 14 | Crystalline Silica Promotes Rat Fibrocyte Differentiation in Vitro,and Fibrocytes Participate in Silicosis in Vivo显示文摘Objective The aim of this study was to investigate the effects of Si O2 on fibrocytes and whether fibrocytes participate in silicosis in vivo. Methods A macrophagocyte(AM)/fibrocyte coculture system was established, and AMs were treated with 100 μg/mL SiO 2. Flow cytometry was used to detect the number of fibrocytes. Real‐time PCR was performed to measure the expression of collagen I, collagen III, and α‐SMA mR NA. The levels of collagen I, collagen III, and TGF‐β1 protein were determined by ELISA. Immunohistochemical staining was performed to measure α‐SMA protein expression. A rat silicosis model was induced by intratracheal instillation of SiO 2. Lung histopathological evaluation was conducted using HE and Masson's trichrome staining after 1 and 9 weeks. The number of fibrocytes in peripheral blood or lung tissue of rat was detected by flow cytometry. Double‐color immunofluorescence was applied to identify fibrocytes in the lung tissue. Results Peripheral blood monocytes were found to differentiate into fibrocytes in vitro in a time‐dependent manner, and exposure to crystalline silica might potentiate fibrocyte differentiation. In addition, fibrocytes were able to migrate from peripheral blood to the lung tissue, and the number of fibrocytes was increased after SiO 2 exposure. Conclusion Silica exposure potentiates fibrocyte differentiation, and fibrocytes may participate in silicosis in vivo. | LI Juan YAO Wu HOU Jian Yong Zhang Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao HAO Chang Fu | 2017 | Biomedical and Environmental Sciences2017，30，9： | 7 |
| 15 | Protective effect of Saccharomyces boulardii on intestinal mucosal barrier of dextran sodium sulfate-induced colitis in mice显示文摘Background: The effect and mechanism of Saccharomyces boulardii (Sb) in inflammatory bowel disease are unclear. The objective of the study was to evaluate the impact of Sb on intestinal mucosal barrier and intestinal flora in a colitis mouse model. Methods: Forty C57BL/6J male mice were randomly assigned to five groups: normal control group (A), pathologic control group (B), Sb treatment group (C), mesalazine treatment group (D), and Sb combined with mesalazine treatment group (E). Colitis was induced by the addition of 2.5%(wt/vol) dextran sodium sulfate (DSS) in the drinking water ad libitum for 7 days. The general condition, weight change, stool property, and bloody stool level of mice were observed to evaluate the disease activity index. The expression of zona occludens-1 (ZO-1) and occludin in intestinal tissue were measured by immunohistochemistry. The level of tumor necrosis factor-α(TNF-α) and interleukin (IL)-8 in plasma was measured by enzyme linked immunosorbent assay. Inter-cellular tight junctions were observed by transmission electron microscopy. The feces and intestinal contents were collected sterilely, and intestinal flora was analyzed by 16S rRNA sequencing. Results: Compared with group B, Sb reduced the disease activity index and histological score of group C (disease activity index: group B 2.708 ± 0.628, group C 1.542 ± 0.616, PBC = 0.005;histological score: group B 9.875 ± 3.271, group C 4.750 ± 1.832, PBC = 0.005) in DSS-induced colitis in mice. Sb exerted a protect effect on the expression of ZO-1 (group B 2.075 ± 1.176, group C 4.225 ± 1.316, PBC = 0.019) and occludin (group B 2.200 ± 0.968, group C 3.525 ± 1.047, PBC = 0.023). Compared with group B, Sb decreased the level of TNF-α and IL-8 of group C (TNF-α: group B 716.323 ± 44.691 ng/L, group C 521.740 ± 90.121 ng/L, PBC = 0.001;IL-8: group B 128.992 ± 11.475 pg/mL, group C 106.283 ± 15.906 pg/mL, PBC = 0.012). Treatment with Sb preserved the tight junctions and ameliorated microvilli and inter-cellular space. Treatment with Sb also showed its own characteristics: a higher percentage of Bacteroidetes and a lower percentage of Firmicutes, with significant differences or a significant trend. The proportion of the S24-7 family was increased significantly in the Sb treatment group. Conclusions: Sb shows an anti-inflammatory effect and has a protective effect on the intestinal mucosal mechanical barrier. Sb may up-regulate the abundance of family S24-7 specifically, and maybe a mechanism underlying its function. | Jin-Pei Dong Yue Zheng Ting Wu Qun He Gui-Gen Teng Hua-Hong Wang | 2019 | Chinese Medical Journal2019，，16： | 7 |
| 16 | Metabonomic analysis of plasma biochemical changes in pyrexia rats after treatment with Gegenqinlian decoction,aspirin and itraconazole by UHPLC-FT-ICR-MS显示文摘A metabonomic approach involving an ultrahigh-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry(UHPLC-FT-ICR-MS)was used to investigate the changes in the endogenous metabolites in the plasma of rats with yeast-induced pyrexia treated with Gegenqinlian decoction(GQLD),aspirin and itraconazole.The differences in the small molecule profiles of treatment using traditional Chinese medicine,etiological treatment and symptomatic treatment were elucidated.Thirty-six plasma metabolites were identified or putatively identified,and the effects of the three medicines on the thirty-six metabolites were studied.Their metabolic pathways indicated that GQLD,aspirin and itraconazole ameliorated the rats with yeast-induced pyrexia predominantly by regulating the metabolisms of phospholipid,sphingolipid,fatty acid oxidation,fatty acid amides,amino acid and glycerolipid in vivo.The pharmacodynamics and metabonomic results showed that the three medicines exhibited the therapeutic effects on pyrexia by regulating the perturbations of multiple metabolisms.The study provided a scientific basis for an in-depth understanding of the therapeutic effects of GQLD,aspirin and itraconazole on rats with yeast-induced pyrexia. | Ting Liu Ruiyun Li Yue Cui Zhiguo Yu Yunli Zhao | 2020 | Journal of Pharmaceutical Analysis2020，10，6： | 6 |
| 17 | Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium显示文摘 | Hui Zhang Xiuzhen Huang Kuo Liu Juan Tang Lingjuan He Wenjuan pu Qiaozhen Liu Yan Li Xueying Tian Yue Wang Libo Zhang Ying Yu Hongyan Wang Ronggui Hu Fengchao Wang Ting Chen Qing-Dong Wang Zengyong Qiao Li Zhang Kathy O Lui Bin Zhou | 2017 | Cell Research2017，27，9： | 6 |
| 18 | Dynamic characteristics analysis and flight control design for oblique wing aircraft显示文摘The movement characteristics and control response of oblique wing aircraft(OWA) are highly coupled between the longitudinal and lateral-directional axes and present obvious nonlinearity. Only with the implementation of flight control systems can flying qualities be satisfied. This article investigates the dynamic modeling of an OWA and analyzes its dynamic characteristics.Furthermore, a flight control law based on model-reference dynamic inversion is designed and verified. Calculations and simulations show that OWA can be trimmed by rolling a bank angle and deflecting the triaxial control surfaces in a coordinated way. The oblique wing greatly affects longitudinal motion. The short-period mode is highly coupled between longitudinal and lateral motion,and the bank angle also occurs in phugoid mode. However, the effects of an oblique wing on lateral mode shape are relatively small. For inherent control characteristics, symmetric deflection of the horizontal tail will generate not only longitudinal motion but also a large rolling rate. Rolling moment and pitching moment caused by aileron deflection will reinforce motion coupling, but rudder deflection has relatively little effect on longitudinal motion. Closed-loop simulations demonstrate that the flight control law can achieve decoupling control for OWA and guarantee a satisfactory dynamic performance. | Wang Lixin Xu Zijian Yue Ting | 2016 | Chinese Journal of Aeronautics2016，29，6： | 6 |
| 19 | Suggestion for aircraft flying qualities requirements of a short-range air combat mission显示文摘Owing to the lack of a direct link with the operations in short-range air combat,conventional aircraft flying qualities criteria are inappropriate to guide the design of a task-tailored flight control law.By applying the mission-oriented flying qualities evaluation approach,various aircraft with different control law parameters are evaluated on a ground-based simulator.This paper compares the evaluation results with several conventional flying qualities criteria,and discusses the appropriate parameter combination to reflect the flying qualities requirements of short-range air combat.The comparison and analysis show that a short-range air combat mission requires a higher minimum short period mode natural frequency and a smaller maximum roll mode time constant,and allows a lower minimum pitch attitude bandwidth and a higher maximum short period mode damp ratio than those of conventional flying qualities criteria.Furthermore,a combination of the pitch attitude bandwidth,the pitch attitude magnitude at the bandwidth frequency,and the pitch attitude transfer function gain can define the flying qualities requirements of short-range air combat.The new metric can successfully predict the flying quality levels of aircraft in a short-range air combat mission. | Lixin WANG Youguang GUO Qi ZHANG Ting YUE | 2017 | Chinese Journal of Aeronautics2017，30，3： | 5 |
| 20 | Selective removal of heavy metal ions in aqueous solutions by sulfide-selector intercalated layered double hydroxide adsorbent显示文摘Remaining largely under-appreciated, a majority of metal ion sorbents are limited in their target selectivity. In this work, a 3D sulfide intercalated NiFe-layered double hydroxide (NFL-S) hierarchical sorbent has been synthesized for selective heavy metal removal. The intercalation of sulfurated groups in the interlayer of the layered double hydroxide (LDH) nanosheets endows NFL-S as a selective heavy metal ion filter;the selectivity of NFL-S for heavy metals is in the order of Pb^2+> Cu^2+≥ Zn^2+> Cd^2+> Mn^2+, and NFL-S has high kd values for Pb2+(~10^6 mL/g) and Cu2+(~10^5 mL/g). Scanning electron microscopy. X-ray photoelectron spectroscopy and powder X-ray diffraction were used to analyze the composition of the as-prepared nanoadsorbent. The selective adsorption behavior was systematically studied using batch experiments, and the performance was evaluated through kinetic and isotherm studies. Moreover, the adsorption mechanism of heavy metals by NFL-S through surface complexation was also investigated, which shows great potential for water decontamination. | Jing Wang Liang Zhang Tianshu Zhang Ting Du Tao Li Tianli Yue Zhonghong Li Jianlong Wang | 2019 | Journal of Materials Science & Technology2019，35，9： | 5 |
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