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| 1 | Efficacy and safety of Xinfeng capsule in patients with rheumatoid arthritis:a multi-center parallel-group double-blind randomized controlled trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of Xinfeng capsule in patients suffering rheumatoid arthritis(RA).METHODS:A multi-center parallel-group designed,double-blind,randomized,controlled trial was conducted.Totally 304 RA patients were assigned to two groups:one group was administered Xinfeng capsule(XFC) plus the placebo of leflunomide and the other given leflunomide(LEF) plus the placebo of XFC for twelve weeks.The clinical and laboratory parameters were compared at baseline and fourth,eighth,and twelfth weeks.RESULTS:After twelve-week treatment,patients in two groups all showed some trend of effectiveness when compared in terms of American Rheumatism Association(ACR) recommended 20%,50%,70%improvement criteria,but it was insignificant.The validity in ameliorate modified disease activity score(DAS28) and laboratory indexes as erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),rheumatoid factor(RF) were also found no difference.The score of health assessment questionnaire(HAQ),self-rating anxiety scale(SAS),self-rating depression scale(SDS) and quality of life questionnaire with rheumatoid arthritis(RAQOL)both lower than the first week and the changes showed no difference.However,the score of SDS dropped more in XFC group than in the other.A total of 147 adverse reaction cases were reported,which shows no difference between the two groups.The most common adverse reactions were hepatic impairment,anemia,leukocytopenia,epigastric discomfort and phalacrosis.CONCLUSION:XFC demonstrated better improvement in the scores of SDS and compared with those of LEF group. | Liu Jian Wang Yuan Huang Chuanbing Xu Jianhua Li Zhijun Xu Liang He Liyun Sun Yue Wang Yali Xu Shengqian Zhao Ping Mao Tongjun Tan Bin Zhu Fubing Zhang Pingheng Fang Li | 2015 | Journal of Traditional Chinese Medicine2015，35，5： | 27 |
| 2 | Matrix metalloproteinase 2 promotes cell growth and invasion in colorectal cancer显示文摘Colorectal 癌症(CRC ) 是在西方的世界上的癌症相关的死亡的第三个领先的原因。在这研究,我们计算了矩阵 metalloproteinase 的表达式在 CRC 的 2 基因(MMP2 ) 并且与 clinicopathological 特征分析了它的关联。我们发现 MMP2 的表示比在 colorectal 纸巾在 CRC 纸巾是显著地更高的。另外, MMP2 蛋白质的高水平断然与肿瘤尺寸,淋巴节点转移,远转移,公爵阶段,和肿瘤侵略的地位被相关。而且,有更高的 MMP2 层次的病人与低 MMP2 层次比那些有显著地更短的全面幸存。Multivariate 分析结果建议 MMP2 表示的水平是为有 CRC 的病人的幸存的独立预示的指示物。在有调停 lentiviral 的 shRNA 的 CRC 房间线的 Silencing MMP2 表示显著地压制了房间增长,殖民地形成,和侵略。而且,我们观察到那个脉管的 endothelial 生长因素(VEGF ) 和膜打 1 (MT1 )-MMP 蛋白质层次在 MMP2-down-regulated colorectal 细胞被减少。因此,我们的学习证明 MMP2 是与 CRC 的 carcinogenesis 和转移有关的一个重要因素,并且 MMP2 由起来调整的 VEGF 和 MT1-MMP 表示支持 CRC 房间生长和侵略,它为癌症治疗使这条小径成为一个潜在的目标。 | Wei Dong Hong Li Yan Zhang Heng Yang Min Guo Li Li Tongjun Liu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，11： | 10 |
| 3 | Process for improving the ladle free- opening rate for high aluminum steel in continuous casting显示文摘Steel 20Mn23AlV is a type of high aluminum steel with a very low ladle free-opening rate. The aluminum composition of 20Mn23AlV ranges from 1. 6% to 2. 45%,which is significantly higher than other types of steel.According to the real condition of 40 t ladle in steel-making plant of Baosteel Special Steel Company,previous works show that the key factors affecting the ladle free-opening rate of high aluminum steel in continuous casting are: sand material,accessories baking,ladle nozzle cleaning,the process and amount of adding sand,and the rate of argon stirring during refining. Therefore,improving the ladle filler sand quality,baking all of the raw materials,controlling the addition of ladle filler sand,cleaning the ladle nozzle,and optimizing argon stirring during the refining process can resolve the problem of a low ladle free-opening rate of high aluminum steel caused by the long ladle time of liquid steel. | LIU Junzhan ZHOU Tongjun LUO Hui | 2015 | Baosteel Technical Research2015，9，1： | 3 |
| 4 | Down-regulation of GPR137 expression inhibits proliferation of colon cancer cells显示文摘G 联合蛋白质的受体(GPR ) 是高度与 oncogenesis 和癌症转移有关。G 联合蛋白质的受体(GPR137 ) 137 大约 10 年以前开始作为新奇孤儿 GPR 被报导。一些孤儿 GPR 在人的癌症被含有。这研究的目的是在人的结肠癌调查 GPR137 的角色。GRP137 的表示层次被量的聚合酶链反应和西方的污点分析在不同结肠癌房间线分析。调停 Lentivirus 的短发卡 RNA 明确地被设计在结肠癌房间将 GPR137 表示击倒。房间生存能力被 methylthiazoletetrazolium 和殖民地形成试金测量。另外,房间周期特征被流动 cytometry 调查。GRP137 表示在不同层次在所有七根结肠癌房间线被观察。GPR137 的 mRNA 和蛋白质层次在在 lentivirus 感染以后的 HCT116 和 RKO 房间是下面调整的。GPR137 的调停 Lentivirus 的 silencing 减少了增长率和殖民地数字。在导致的两根房间线的 GPR137 击倒在 G 0/G1 阶段的房间周期拘捕。这些结果显示 GPR137 在结肠癌房间增长起一个重要作用。GPR137 在结肠癌房间的信号 transduction 小径上的效果的更好的理解可以提供卓见进结肠癌的新奇基因治疗。 | Kai Zhang Zhen Shen Xianjun Liang Tongjun Liu Tiejun Wang Yang Jiang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，11： | 3 |
| 5 | Preparation of Au NPs/ZnO NTs Hybrid Array and Its Photo Catalytic Performance for MO显示文摘X-ray diffraction, scanning electron microscopy and transmission electron microscopy were employed to investigate the microstructure and morphology of Au NPs/ZnO NTs, and their photo-catalytic capability was assessed to a nicety. The results demonstrated that the diameter and the wall thickness of ZnO nanotube were about 200 and 50 nm, respectively. The diameter of Au nanoparticle was about 30 nm. The characterization on the photo-catalytic capability of the Au-ZnO nanotube hybrid indicated that the degradation of methyl orange was 80% within 4 h. Controlled experiments have shown that Au-Zn O nanotube hybrid presents superior photo-catalytic capability to both bare ZnO nanorod and Au-ZnO nanorod hybrid indicated that the degradation procedure of methyl orange. | 曾天 WEI Jin LIU Lin DENG Jiatao ZHENG Gang ZHANG Pei NIU Tongjun JIAO Zhifeng JIN Yong 孙小松 | 2018 | Journal of Wuhan University of Technology(Materials Science)2018，33，3： | 2 |
| 6 | An investigation into effect of cationic precursor solutions on formation of CuInSe2 thin films by SILAR method显示文摘 | Yang Jingxia Jin Zhengguo Liu Tongjun | 2008 | Solar Energy Materials & Solar Cells2008，92，： | 1 |
| 7 | Distribution system power flow based on loop-impedance equations显示文摘 | Wang Shouxiang Liu Yutian Ruan Tongjun | 1998 | IEEE Proceedings-Generation Transmission and Distribution1998，5，1： | 1 |
| 8 | The effects of corn silk on glycaemic metabolism显示文摘 | Guo Jianyou Liu Tongjun Han Linna | | 0，，01： | 1 |
| 9 | TPX2 regulates tumor growth in human cervical carcinoma cells显示文摘 | Peiyue Jiang Kexin Shen Xuerui Wang Haiqin Song Ying Yue Tongjun Liu | 2014 | Molecular Medicine Reports2014，，6： | 1 |
| 10 | Genesis of Kaolinite Deposits in the Jungar Coalfield,North China:Petrological,Mineralogical and Geochemical Evidence显示文摘Petrological,mineralogical and geochemical studies carried out on kaolinite deposits in Haerwusu surface mine,Jungar Coalfield,northern Ordos Basin,North China,define their characteristics,ore genesis and economic interest.Based on the crystalline size,two different types of kaolinite rocks,cryptocrystalline and grainy,were identified under the microscope.XRD data show that kaolinite is the predominant mineral,associated with boehmite,magnesite,anatase,pyrite,diaspore and calcite.However,high boehmite content(mean 70%)shows up in the middle layers.Kaolinite minerals present homogeneous shape and a good crystallinity(HI=0.96–1.26).Geochemical studies show that the SiO_(2)/Al_(2)O_(3)molar ratio of kaolinite is close to the theoretical value,and the contents of Na_(2)O,K_(2)O,CaO,Mg O are less,suggesting a strong chemical weathering environment.The REE and Eu anomalies show a close relationship between kaolinite and the Yinshan Oldland granite.A Ce anomaly reflects a continental sedimentary environment with shallow water.A temperature range of 26.7–34℃was calculated on the basis of the isotopic signatures(δ18O,δD)of the kaolinite rocks.All these data indicate that the formation of the kaolinite is caused mainly by the dissolution,coagulation,precipitation and recrystallization of aluminosilicate clastics in acidic conditions.The formation of boehmite in the middle layers indicates that the source rocks have changed.Boehmite is mainly formed by dehydration and compaction of an aluminum-rich colloid which transported into peat swamp during diagenesis.In addition,it formed by desiliconization of kaolinite under acidic conditions.Due to its high kaolinite content(up to 90%)and low iron mineral content(less than 1%),and good crystallinity,kaolinite deposits occurred at Haerwusu surface mine probably have great economical value in the future. | LIU Linsong ZHANG Tongjun LIU Jianping LIU Qinfu LI Kuo LIU Di LIU Wanyue | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 1 |
| 11 | The effects of corn silk on glycaemic metabolism 显示文摘 | GUO Jianyou LIU Tongjun I-IAN Linna | 2009 | Nutri- tion & Metabolism2009，，6： | 1 |
| 12 | Preparation and process chemistry of SnO2 films derivedfrom SnC2O4 by the aqueous sol-gel method 显示文摘 | LIU Tongjun JIN Zhengguo YANG Jingxia | 2008 | Journal of the American Ceramic Society2008，91，： | 1 |
| 13 | Separate and concurrent use of 2-deoxy-D-glucose and 3-bromopyruvatein pancreatic cancer cells显示文摘 | Huijie Xiao Shasha Li Dapeng Zhang Tongjun Liu Ming Yu Feng Wang | 2013 | Oncology Reports2013，，1： | 1 |
| 14 | Novel chitosan/collagen scaffold containing transforming growth factor-β1 DNA for periodontal tissue engineering显示文摘 | Yufeng Zhang Xiangrong Cheng Jiawei Wang Yining Wang Bin Shi Cui Huang Xuechao Yang Tongjun Liu | 2006 | Biochemical and Biophysical Research Communications2006，，1： | 1 |
| 15 | Flow field research on bottom argon blowing in a 40 ton ladle显示文摘In order to improve argon blowing efficiency in a 40 ton ladle,numerical simulation and water simulation experiments of the bottom argon flowwere performed.Relationships among the ladle mixing time,slag eye area,different blowing flowrates,and different blowing positions(0,0.56 R,0.62 R,0.67R) are discussed.Results showed that the ladle mixing time decreased when the argon blowing brick distance(from bottom center of the ladle) increased,and decreased significantly when the blowing flowincreased from 70 to 130 L / h.When the blowing flowincreased and exceeded 130 L / h,the stirring effect tended to be stable,and there was little effect on the ladle mixing time.The slag eye area increased as the argon brick distance increased,and was larger when the argon blowbrick was near the ladle wall.Wall shear stress significantly increased as the brick distance increased and was concentrated at the slag wall near the argon flowbrick; this is called the most serious erosion wall.The average wall shear increased exponentially with increasing argon blowing brick distance. | ZHOU Tongjun LIU Junzhan LUO Hui | 2016 | Baosteel Technical Research2016，10，3： | 0 |
| 16 | Genesis and tectonic setting of Early Jurassic granitic rocks in Huashan Town,Xingcheng,western Liaoning显示文摘There are a large number of Mesozoic intrusive and volcanic rocks in western Liaoning of China,which is an ideal place to study the Mesozoic Paleo-Pacific subduction processes,and lithospheric destruc-tion of North China Craton.Detailed petrographic,zircon U-Pb dating and geochemical studies of the Early Jurassic granites in Huashan pluton,Xingcheng,western Liaoning,indicate that the Early Jurassic granites were formed at 184-174 Ma,mainly composed of syenite and monzogranite.The geochemical characteristics show high contents of SiO_(2),Al_(2)O_(3)and Na_(2)O+K_(2)O,low contents of Fe_(2)O_(3)and MgO,enrichment in LREEs and LILEs,and depletion in HREEs and HFSEs,and have a high content of Sr and low contents of Y and Yb,with weak negative Eu anomalies and slightly negative anomalies of Ce,indicating that they are a set of intermediate-acidic adakitic granites in high-K calc-alkaline series.All the facts significantly suggest that the Early Jurassic adakitic granites were formed at the active continental margin in the context of Paleo-Pacific plate subduction. | ZHAO Junfeng LI Weimin LIU Tongjun GAO Jinhui | 2024 | Global Geology2024，27，1： | 0 |
| 17 | A Pregnant Woman Died of Sudden Cardiac Death:Should Esophageal Foreign Body Be Considered an Inductive Factor?A Case Report and Literature Review显示文摘Here,we report a case of acute attack of coronary heart disease(CHD).A 47‑year‑old pregnant woman with gestational hypertension developed sudden‑onset chest tightness,palpitations,dyspnea,and cyanosis of the face and lips after admission.Her blood pressure was 180/110 mmHg and her blood oxygen saturation was 45%at that time.After cardiopulmonary resuscitation,a weak heartbeat was restored,but oxygen saturation did not increase significantly.Therefore,she was transferred to the intensive care unit;however,she died after 21 days of admission.Autopsy findings revealed that a foreign body was embedded in the esophagus near the right piriform,and her heart weighed 392 g;histopathological examination revealed CHD,thrombosis in the lumen of the right coronary artery,cardiomyocyte hypertrophy,vascular hyaline degeneration in arterioles,neutrophils in the bronchiole and alveolar.All the tested samples yielded negative toxicological results.Clinical status and autopsy findings were not compatible with a diagnosis of peripartum cardiomyopathy.The patient’s sudden death was attributed to CHD,and esophageal foreign‑body impaction was considered to be concomitant phenomenon.Our findings might help in increasing the awareness between esophageal foreign‑body impaction and sudden cardiac death and they can also help in clarifying that understanding the primary cause of death is the key to resolving an iatrogenic medical tangle. | Chang Cao Mingming Li Zhanzhan Liu Shiyong Fang Gang Chen Guang Chen Tongjun Ma Xuyang Zhu Xiang Xu | 2022 | Journal of Forensic Science and Medicine2022，8，4： | 0 |
| 18 | A Facial Size Automatic Measurement and Analysis Technology显示文摘Facial measurement and analysis is an important part of anthropometry,which provides data support for the design of facial protective equipment.To overcome the inconveniences,low efficiency and poor measurement accuracy of facial size parameters measured and analyzed by manual contact,a method of automatic measurement and analysis of face size parameters is proposed.First,the automatic marking method of faces based on deep learning can improve the efficiency ofmeasuring facial parameters.Then,facial parameters,including nose middle width,nose width,face width and eye width,can be measured.Finally,the data set of face size parameters is classified and counted based on fuzzy clustering analysis.Sixty-five groups of Han youth facial data are collected formeasurement and analysis,and compared with the existing algorithms,the facial morphology analysis system presented in this paper has higher measurement accuracy. | Dongliang Yang Changjiang Song Hantao Zhao Tongjun Liu | 2022 | 国际计算机前沿大会会议论文集2022，，2： | 0 |
| 19 | Down-regulation of GPR137 expression inhibits proliferation of colon cancer cells显示文摘Due to questions raised regarding experimental data/plasmid vectors in the article entitled‘Down-regulation of GPR137 expression inhibits proliferation of colon cancer cells’by Kai Zhang,Zhen Shen,Xianjun Liang,Tongjun Liu,Tiejun Wang and Yang Jiang,published online:October 9,2014(https://academic.oiip.com/abbs/article/46/11/935/1265)in Acta Biochim Biophys Sin(DOI:10.1093/abbs/gmu086),the editors have decided to retract this article and the authors apologize to the readers and editors of Acta Biochim Biophys Sin for any inconvenience caused. | Kai Zhang Zhen Shen Xianjun Liang Tongjun Liu Tiejun Wang Yang Jiang | 2019 | Acta Biochimica et Biophysica Sinica2019，51，5： | 0 |
| 20 | Research and application of numerical simulation to optimization of ingot casting process显示文摘During the ingot casting process,the parametric changes of the molten steel pouring process often cause both ingot surface and internal quality defects. With the increasingly wide application of computers in industrial technology,numerical simulations of the molten steel pouring process enable predictions of the defects that will arise during the pouring and solidification process,especially for the molten steel flowduring the early stages of casting. In addition,using a computer to simulate the casting process of a 40 t ingot and solidification can prevent many defects. The simulation results indicate that controlling the pouring speed to less than 80 kg / s,hanging the casting powder in a mold with the hanging height maintained at 100-150 mm,and controlling the taper angle of the mold brick outlet to a suitable level can reduce the probability of slag entrapment and improve the internal and surface quality of the ingot. | ZHOU Tongjun LIU Junzhan LUO Hui | 2015 | Baosteel Technical Research2015，9，3： | 0 |
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