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| 1 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 2 | Erratum to: Sn^(4+) precursor enables 12.4% efficient kesterite solar cell from DMSO solution with open circuit voltage deficit below 0.30 V (vol 64, issue 1, page 52, 2021)显示文摘In the version of the article originally published in volume 64,issue 1,2021 of Sci China Mater(2021,64(1):52–60,https://doi.org/10.1007/s40843-020-1408-x),the chemical formula of Sn(DMSO)_(4)Cl_(4)(page 54,8^(th) line in the left column;page 56,4^(th) and 6^(th) lines from the bottom of left column and in Equations(6 and 7)in the right column)was miswritten.The correct formula should be as below:SN(DMSO)_(2)CL_(4). | Yuancai Gong Yifan Zhang Erin Jedlicka Rajiv Giridharagopal James A.Clark Weibo Yan Chuanyou Niu Ruichan Qiu Jingjing Jiang Shaotang Yu Sanping Wu Hugh W.Hillhouse David S.Ginger Wei Huang Hao Xin | 2021 | Science China Materials2021，64，5： | 7 |
| 3 | Exome sequencing reveals genetic architecture in patients with isolated or syndromic short stature显示文摘Short stature is among the most common endocrinological disease phenotypes of childhood and may occur as an isolated finding or in conjunction with other clinical manifestations.Although the diagnostic utility of clinical genetic testing in short stature has been implicated,the genetic architecture and the utility of genomic studies such as exome sequencing(ES)in a sizable cohort of patients with short stature have not been investigated systematically.In this study,we recruited 561 individuals with short stature from two centers in China during a 4-year period.We performed ES for all patients and available parents.All patients were retrospectively divided into two groups:an isolated short stature group(group I,n=257)and an apparently syndromic short stature group(group II,n=304).Causal variants were identified in 135 of 561(24.1%)patients.In group I,29 of 257(11.3%)of the patients were solved by variants in 24 genes.In group II,106 of 304(34.9%)patients were solved by variants in 57 genes.Genes involved in fundamental cellularprocess played an important role in the genetic architecture of syndromic short stature.Distinct genetic architectures and pathophysiological processes underlie isolated and syndromic short stature. | Xin Fan Sen Zhao Chenxi Yu Di Wu Zihui Yan Lijun Fan Yanning Song Yi Wang Chuan Li Yue Ming Baoheng Gui Yuchen Niu Xiaoxin Li Xinzhuang Yang Shiyu Luo Qiang Zhang Xiuli Zhao Hui Pan Mei Li Weibo Xia Guixing Qiu Pengfei Liu Shuyang Zhang Jianguo Zhang Zhihong Wu James R.Lupski Jennifer E.Posey Shaoke Chen Chunxiu Gong Nan Wu | 2021 | Journal of Genetics and Genomics2021，48，5： | 2 |
| 4 | Mechanism and catalytic performance for direct dimethyl ether synthesis by CO2 hydrogenation over CuZnZr/ferrierite hybrid catalyst显示文摘Direct synthesis of dimethyl ether(DME)by CO2 hydrogenation has been investigated over three hybrid catalysts prepared by different methods:co-precipitation,sol-gel,and solid grinding to produce mixed Cu,ZnO,ZrO2 catalysts that were physically mixed with a commercial ferrierite(FER)zeolite.The catalysts were characterized by N2 physisorption,X-ray diffraction(XRD),transmission electron microscopy(TEM),X-ray photoelectron spectroscopy(XPS),temperature programmed desorption of CO2(CO2-TPD),temperature programmed desorption of NH3(NH3-TPD),and temperature programmed H2 reduction(H2-TPR).The results demonstrate that smaller CuO and Cu crystallite sizes resulting in better dispersion of the active phases,higher surface area,and lower reduction temperature are all favorable for catalytic activity.The reaction mechanism has been studied using in situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS).Methanol appears to be formed via the bidentate-formate(b-HCOO)species undergoing stepwise hydrogenation,while DME formation occurs from methanol dehydration and reaction of two surface methoxy groups. | Qingtao Sheng Run-Ping Ye Weibo Gong Xiufeng Shi Bang Xu Morris Argyle Hertanto Adidharma Maohong Fan | 2020 | Journal of Environmental Sciences2020，32，6： | 2 |
| 5 | The Monitoring and Early Detection of Intemet Worms显示文摘 | Zou C C Gong Weibo Towsley D | 2005 | IEEE/ACM Trans on Networking2005，13，5： | 1 |
| 6 | Modeling and Simulation Study of the Propagation and Defense of lnternet E-mail Worms显示文摘 | Zou C C Towsley D Gong Weibo | 2007 | IEEE Transactions on Dependable and Secure Computing2007，4，2： | 1 |
| 7 | Code red worm propagation modeling and analysis显示文摘 | Cliff Changchun Zou Weibo Gong Don Towsley | 2002 | ACM CCS2002，10，： | 1 |
| 8 | Modeling Malware Spreading Dynamics 显示文摘 | Garetto M Gong Weibo Towsley D | 2003 | IEEE Infocom2003，，4： | 1 |
| 9 | The monitoring and early detection of Internet worms显示文摘 | Zou Cliff Changchun Gong Weibo Towsley Don | 2005 | IEEE/ACM Transactions on Networking2005，13，： | 1 |
| 10 | Fluid-based Analysis of a Network of AQM Routers Supporting TcP Flows with an Application to RED 显示文摘 | Vishal Misra Gong Weibo Don Towsley | 2000 | Computer Communication Review2000，30，4： | 1 |
| 11 | Modeling and simulation study of the propagation and defense of internet E-mail worms 显示文摘 | ZOU C C TOWSLEY D GONG Weibo | 2007 | IEEE Transactions on dependable and Secure Computing2007，4，2： | 1 |
| 12 | cRGD-functionalized, DOX-conjugated, and 64 Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging显示文摘 | Xiaoqiang Yang Hao Hong Jamison J. Grailer Ian J. Rowland Alireza Javadi Samuel A. Hurley Yuling Xiao Yunan Yang Yin Zhang Robert J. Nickles Weibo Cai Douglas A. Steeber Shaoqin Gong | 2011 | Biomaterials2011，，17： | 1 |
| 13 | On the performance of Internet worm scanning strategies显示文摘 | Cliff C Z Towsley D Gong Weibo | 2006 | Per formance Evaluation2006，63，7： | 1 |
| 14 | The Monitoring and Early Detection of Internet Worms显示文摘 | Zou C C Gong Weibo Towsley D | 2005 | IEEE/ACM Transactions on Networking2005，13，5： | 1 |
| 15 | Phylogenetic investigation on five genera of tintinnid ciliates (Ciliophora, Choreotrichia), based on the small subunit ribosomal RNA gene sequences显示文摘The phylogenetic relationship among tintinnid ciliates are relatively poorly studied based on molecular data. In the present work, seven species belonging to five genera of the order Tintinnida (Amphorellopsis acuta, Codonellopsis nipponica, Favella taraikaensis, Steno-semella nivalis, Tintinnopsis beroidea, Tintinnopsis cylindrica and Tintinnopsis lohmanni) were analyzed using the information on their small subunit ribosomal RNA gene sequences. Phylogenetic trees were constructed using Bayesian inference (BI), maximum parsimony (MP), neighbor-joining (NJ), and least-squares (LS) methods. Generally, similar topologies were revealed with high or moderate supports, in which the main results show that (1) all tintinnids analyzed belong to a single assemblage; (2) congeners in Tintinnopsis do not cluster together, which indicates that the lorica-based definition for this genus is not consistent with the SSU rRNA phylogeny; (3) A. acuta groups with Tintinnidium mucicola but not with Eutintinnus, indicating that the traditional family Tintinnidae might be a paraphyletic group; (4) Stenosemella and Codonellopsis are clearly most related and possibly even merged into one genus regarding their similar morphology and molecular analyses, and possession of a hyaline collar is the only characteristic of the genus. | Zicong Li Zhenzhen Yi Jinpeng Yang Jun Gong John C. Clamp Khaled A.S. Al-Rasheid Saud Al-Arifi Abdulaziz A. Al-Khedhairy Weibo Song | 2009 | Progress in Natural Science:Materials International2009，19，9： | 1 |
| 16 | Fluid-based Analysis of a Network of AQM Routers Supporting TCP Flows with an Application to RED显示文摘 | MISRA V GONG Weibo TOWSLEY D | 2000 | Computer Communication Review2000，30，4： | 1 |
| 17 | Nuclear events during conjugation in the poorly studied model ciliate Paramecium jenningsi显示文摘Ciliated protists are highly differentiated unicellular eukaryotes that possess special sexual processes(conjugation and autogamy)that rely on their unique nuclear dimorphism,i.e.,the presence of both a germline micronucleus(MIC)and a somatic macronucleus(MAC)in a single cell.The sexual processes show a high diversity in different ciliates.To better understand the differentiation and evolution of sexual processes in closely related species,we investigated the nuclear events during conjugation in Paramecium jenningsi strain GZ,a poorly studied close relative of the well-known P.aurelia complex.The main results include:(1)the conjugation process takes about 48 h,including three prezygotic divisions(meiosis I,II,and mitosis)and three postzygotic divisions;(2)the MICs are dominated by the“parachute”phase at the prophase of meiosis I;(3)after meiosis II,a variable number of nuclei undergo the third prezygotic division,and the two products near the paroral cone become the genetically identical migratory and stationary pronuclei;(4)the synkaryon divides three times to form the MIC and the MAC anlagen,but only one nuclear product of the first postzygotic division completes the next two divisions;and(5)an extra cell division is required to complete the last step of conjugation,during which two MIC anlagen undergo mitotic division while two MAC anlagen are distributed between the daughter cells without division.The comparison of the nuclear events during conjugation in representatives of the class Oligohymenophorea reveals that usually there are three prezygotic divisions and a variable number of postzygotic divisions.However,the number of selected and differentiated nuclei after each division differs among species.This study provided a new model ciliate for further investigations of nuclear selection and differentiation as well as nuclear morphology during meiosis. | Xue Zhang Ruitao Gong Yaohan Jiang Xiaoteng Lu Chenyin Wu Lihan Wang Hongwei Ma Zhengxiang Zhang Weibo Song Khaled A.S.Al-Rasheid Adriana Vallesi Feng Gao | 2023 | Water Biology and Security2023，2，4： | 0 |
| 18 | AN IMPROVED ERROR ANALYSIS FOR FINITE ELEMENT APPROXIMATION OF BIOLUMINESCENCE TOMOGRAPHY显示文摘这篇论文涉及源于分子的成像的区域的一个提出病的问题并且作为 BLT 被知道问题。用 Tikhonov 规则化技术,一个二次的优化问题能被提出。我们为调整优化问题的有限元素近似提供改进错误估计。一些数字例子被举表明我们的理论结果。 | Wei Gong Ruo Li Ningning Yan Weibo Zhao | 2008 | Journal of Computational Mathematics2008，26，3： | 0 |
| 19 | National Memory—National Image—National Security——National Security Ideology and the Theoretical Model显示文摘National security faces the challenge of the 'cross- national- sovereignty-management'model and the'commons'mode. Based on hypothesis,cross- regional security net is formed. As for China,it attaches importance to sovereign states and nations,pursuing the relatively stable evaluation of the international community. And based on the national memory and national communication,the state security awareness provides possibility for surpassing the so- called universal value of the West. | Gong Weibo | 2015 | 学术界2015，，3： | 0 |
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