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| 1 | Topologically Protected Edge State in Two-Dimensional Su–Schrieffer–Heeger Circuit显示文摘Topological circuits,an exciting feld just emerged over the last two years,have become a very accessible platform for realizing and exploring topological physics,with many of their physical phenomena and potential applications as yet to be discovered.In this work,we design and experimentally demonstrate a topologically nontrivial band structure and the associated topologically protected edge states in an RF circuit,which is composed of a collection of grounded capacitors connected by alternating inductors in the x and y directions,in analogy to the Su–Schriefer–Heeger model.We take full control of the topological invariant(i.e.,Zak phase)as well as the gap width of the band structure by simply tuning the circuit parameters.Excellent agreement is found between the experimental and simulation results,both showing obvious nontrivial edge state that is tightly bound to the circuit boundaries with extreme robustness against various types of defects.Te demonstration of topological properties in circuits provides a convenient and fexible platform for studying topological materials and the possibility for developing fexible circuits with highly robust circuit performance. | Shuo Liu Wenlong Gao Qian Zhang Shaojie Ma Lei Zhang Changxu Liu Yuan Jiang Xiang Tie Jun Cui Shuang Zhang | 2019 | Research2019，，1： | 6 |
| 2 | Rb Protein is Essential to the Senescence-Associated Heterochromatic Foci Formation Induced by HMGA2 in Primary WI38 Cells显示文摘细胞的老朽是提供一个障碍给肿瘤的转变的房间周期拘捕的一张不可逆的表格。Rb (Retinoblastoma ) 小径的正直为为衰老的状态的稳定性提供一个分子的基础的联系老朽的 heterochromatin foci (SAHF ) 的形成是必要的。令人惊讶地,尽管高活动性组 A2 蛋白质(HMGA2 ) 能支持 tumorigenesis 并且在肿瘤房间禁止 Rb 功能, HMGA2 的高级表示是足够的在主要房间导致 SAHF 形成。决定 Rb 蛋白质是否在导致 HMGA2 的 SAHF 形成是必要的因此变得重要。在这研究,我们由 HMGA2,典型衰老的标记在被看见的宫外的表示建立了细胞的老朽和 SAHF 汇编 WI38 房间模型,包括 p53, p21 和 p16 的著名 upregulation,并且提高了 SA -- 和 E2F 目标基因的 downregulation 染色的牛乳糖。我们然后证明 Rb 小径禁止者 E7 蛋白质能部分在 WI38 房间在 HMGA2 表示以后废除 SAHF 形成的能力,显示 Rb 是为导致 HMGA2 的 SAHF 形成的一个关键因素。然而, Rb 弄空完全没救 HMGA2 导致的房间生长拘捕,建议 Rb 不是为在 WI38 房间的导致 HMGA2 的老朽的一条独占的小径。 | Xi Shi Baoqing Tian Lingxia Liu Yanyan Gao Chi Ma Namusamba Mwichie Wenlong Ma Liping Han Baiqu Huang Jun Lu Yu Zhang | 2013 | Journal of Genetics and Genomics2013，40，8： | 4 |
| 3 | Petroleum Origins and Accumulation Patterns in the Weixinan Sag in the Beibu Gulf Basin,Using Subsag B as an Example显示文摘Crude oil has been discovered in the Paleogene and Neogene units of the Weixinan Sag in the Beibu Gulf Basin.To determine the source and accumulation mode of this crude oil,12 crude oil samples and 27 source rock samples were collected and an extensive organic geochemical analysis was conducted on them.Based on the geological conditions and the analytical results,the types,origins and accumulation patterns of crude oil in the study area were elucidated.Except for a shallowly-buried and biodegraded crude oil deposit in Neogene rocks,the crude oil samples in the study area were normal.All of the crude oils were derived from lacustrine source rocks.According to biomarker compositions,the crude oils could be divided into two families,A and B,distinctions that were reinforced by differences in carbon isotope composition and spatial distribution.Oil-source correlation analysis based on biomarkers revealed that Family A oils were derived from the mature oil shale at the bottom of the second member of the Liushagang Formation,while the Family B oils formed in the mature shale of the Liushagang Formation.The Family A oils,generated by oil shale,mainly migrated laterally along sand bodies and were then redistributed in adjacent reservoirs above and below the oil shale layer,as well as in shallow layers at high structural positions,occupying a wide distribution range.The Family B oils were generated by other shale units before migrating vertically along faults to form reservoirs nearby,resulting in a narrow distribution range. | GAO Gang XU Xinde QU Tong GAN Jun DANG Wenlong ZHOU Xiaoxiao LIU Fengyan | 2020 | Acta Geologica Sinica(English Edition)2020，94，5： | 3 |
| 4 | Octupole corner state in a three-dimensional topological circuit显示文摘Higher-order topological insulators(HOTIs)represent a new family of topological materials featuring quantized bulk polarizations and zero-dimensional corner states.In recent years,zero-dimensional corner states have been demonstrated in two-dimensional systems in the form of quadrupole modes or dipole modes.Due to the challenges in designing and constructing three-dimensional systems,octupole corner modes in 3D have not been observed.In this work,we experimentally investigate octupole topological phases in a three-dimensional electrical circuit,which can be viewed as a cubic lattice version of the Hofstadter model with aπ-flux threading each plaquette.We experimentally observe in our higher-order topological circuit a 0D corner state manifested as a localized impedance peak.The observed corner state in the electrical circuit is induced by the octupole moment of the bulk circuit and is topologically protected by anticommuting spatial symmetries of the circuit lattice.Our work provides a platform for investigating higher-order topological effects in three-dimensional electrical circuits. | Shuo Liu Shaojie Ma Qian Zhang Lei Zhang Cheng Yang Oubo You Wenlong Gao Yuanjiang Xiang Tie Jun Cui Shuang Zhang | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 5 | Clinical data analysis reveals the role of OGR1 (GPR68) in head and neck squamous cancer显示文摘Background:Head and neck squamous cancer(HNSC)frequently occurs in the clinic.Revealing the role of the genes that correlate with cancer cell outgrowth will contribute to potential treatment target identification and tumor inhibition.Methods:The gene expression profiles and gene ontology of the proton-sensing G-protein-coupled receptor OGR1 were analyzed using the TCGA(The Cancer Genome Atlas)database.The effects of sex,age,race,and degree of malignancy on HNSC were investigated,and the survival times of HNSC patients with high or low/medium expression levels of OGR1 were compared.Methylation of the OGR1 promoter CpG sites was also investigated and OGR1-related genes were analyzed using gene set enrichment analysis.Results:OGR1 is overexpressed in HNSC patients.However,compared with the low/median expression group,the high OGR1 expression group did not have different survival rates.The OGR1 expression level differed across sex,age,race,and degree of malignancy,while the methylation of the OGR1 promoter CpG sites was maintained at a similar level.Gene set enrichment analysis revealed that OGR1 was positively correlated with head and neck cancer,cisplatin resistance,hypoxia,angiogenesis,cell migration,and TGF-β.Conclusion:The expression of OGR1 correlated with HNSC progression and survival and thus can serve as a potential treatment target and prognostic marker. | Wenlong Zhang Yong Han Weisha Li Lin Cao Libo Yan Chuan Qin Ran Gao | 2020 | Animal Models and Experimental Medicine2020，3，1： | 2 |
| 6 | Results of Clinical Trial of Superficially-placed Tumor Therapy with Carbon Ions at Heavy Ion Research Facility in Lanzhou(HIRFL显示文摘 | Zhang Hong Li Sha Wang Xiaohu Li Qiang Zhao Weiping Dai Zhongying Wei Shihua Gao Liying Xiao Guoqing Xu Hushan Hu Zhengguo Mao Ruishi Yue Yangjun Ran Juntao Tian Zhongze Song Mingtao Zhao Hongwei Zhan Wenlong | 2007 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2007，，1： | 2 |
| 7 | Downregulation of HNRNPK in human cancer cells inhibits lung metastasis显示文摘Background: Lung cancer frequently occurs in the clinic, leading to poor prognosis and high mortality. Markers for early diagnosis of lung cancer are scarce, and further potential therapeutic targets are also urgently needed.Method: We established a new mouse model in which the specific gene HNRNPK(heterogeneous nuclear ribonucleoprotein K) was downregulated after administration of doxycycline. The lung metastatic nodules were investigated using bioluminescence imaging, micro-CT, and autopsy quantification.Results: Compared with the short hairpin negative control group, less lung metastatic nodules were formed in the short hairpin RNA group.Conclusion: Downregulation of HNRNPK in cancer cells can inhibit lung metastasis. | Mengyuan Li Wenlong Zhang Xingjiu Yang Hongfei Liu Lin Cao Weisha Li Le Wang Guoxin Zhang Ran Gao | 2019 | Animal Models and Experimental Medicine2019，2，4： | 2 |
| 8 | Effect of Ball-Milling Time on the Performance of Ni-Al2O3 Catalyst for 1,4-Butynediol Hydrogenation to Produce 1,4-Butenediol显示文摘The Ni-Al2O3 catalyst was prepared by the mechanochemical method in combination with a planetary ballmilling machine.Effect of milling time on the crystal structure,the reduction characteristics and the catalytic performance of Ni-Al2O3 catalyst for hydrogenation of 1,4-butynediol to produce 1,4-butenediol were investigated.The catalysts were characterized by PSD,EDX,XRD,H2-TPR,BET,TEM,and NH3-TPD methods.Results showed that the MCt2.5 catalyst treated at a ball milling time of 2.5 h could form a smallest particle size of 191.0 nm.The evaluation experiments revealed that the activity of the prepared catalyst increased at first and then reached a constant value with the extension of ballmilling time.The BYD conversion,BED selectivity and yield on the MCt2.5 catalyst reached 35.63%,33.48%and 32.46%,respectively,which were higher than those obtained by other samples.The excellent performance of MCt2.5 sample is mainly related to the following three reasons from characterization results.Firstly,it has a smallest particle size of 191.0 nm;and then,the surface acidity(in terms of strong acids)of the catalyst was weaker than other catalysts;and eventually,the loading amount(23.84%)of the active component Ni exceeded the theoretical value(20%). | Gao Xianlong Mo Wenlong Ma Fengyun He Xiaoqiang | 2020 | China Petroleum Processing & Petrochemical Technology2020，22，1： | 2 |
| 9 | In situ TEM studies of oxygen vacancy migration for electrically induced resistance change effect in cerium oxides显示文摘 | Peng Gao Zhenzhong Wang Wangyang Fu Zhaoliang Liao Kaihui Liu Wenlong Wang Xuedong Bai Enge Wang | 2009 | Micron2009，，4： | 2 |
| 10 | Effects of simulated atmospheric nitrogen deposition on inorganic nitrogen content and acidification in a cold-temperate coniferous forest soil显示文摘 | Wenlong Gao Shulan Cheng Huajun Fang Yan Chen Guirui Yu Mei Zhou Peilei Zhang Minjie Xu | 2013 | Acta Ecologica Sinica2013，，： | 1 |
| 11 | Energy-to-peak control for seismic-excited buildings with actuator faults and parameter uncertainties显示文摘 | Wenlong Zhang Yang Chen Huijun Gao | 2010 | Journal of Sound and Vibration2010，，4： | 1 |
| 12 | Photo Responsive Silver Nanoparticles Incorporated Liquid Crystalline Elastomer Nanocomposites Based on Surface Plasmon Resonance显示文摘 | ZHANG Jindi WANG Jun ZHAO Lina YANG Wenlong BI Meng WANG Yuchang NIU Hongyan LI Yuxin WANG Binsong GAO Yachen LI Chensha HUANG Xuezhen | 2017 | Chemical Research in Chinese Universities2017，33，5： | 1 |
| 13 | Effect of oxide scale on corrosion behavior of HP-13Cr stainless steel during well completion process显示文摘The well completion process in oil and gas industry,aiming to build effective exploitation,is divided into acidizing and formation water production process.Oxide scale(OS)formed on the inner wall of the HP-13Cr stainless steel tubes during the hot extrusion process changes the surface roughness.The effects of OS on the corrosion of HP-13Cr stainless steel during well completion process were studied by corrosion measurement,spectra analysis,microscopic observation and numerical simulation.The results indicate that the OS make no change of phase distribution and element composition of corrosion scale,while the increasing OS roughness is the dominant factor for accelerating corrosion rate during the well completion process.In acidizing process,the greater surface roughness OS of HP-13Cr stainless steel increases the corrosion rate obviously due to a larger interfacial area in contact with the aggressive environment.During subsequent formation water production process,the turbulence eddy,formed at locations characterized with greater surface roughness OS,can deteriorate the corrosion scale and accelerate the mass transfer of the corrosive species,resulting in more serious corrosion. | Wenlong Qi Jidong Wang Xuanpeng Li Yanan Cui Yang Zhao Junfeng Xie Guanxin Zeng Qiuying Gao Tao Zhang Fuhui Wang | 2021 | Journal of Materials Science & Technology2021，，5： | 1 |
| 14 | Study on Blasting Vibration Effects of Shallow Tunnel Excavation 显示文摘 | GAO Wenxue SUN Wenlong DENG Hongliang | 2011 | Advanced Materials Research2011，，： | 1 |
| 15 | Long-term effects and performance of two-stage baffled surface flow constructed wetland treating polluted river显示文摘 | Wang Wenlong Gao Jingqing Guo Xiao | 2012 | Ecological Engineering2012，49，： | 1 |
| 16 | Finite frequency H ∞ control for building under earthquake excitation显示文摘 | Yang Chen Wenlong Zhang Huijun Gao | 2009 | Mechatronics2009，，1： | 1 |
| 17 | Photonic topological fermi nodal disk in non-Hermitian magnetic plasma显示文摘Topological physics mainly arises as a necessary link between properties of the bulk and the appearance of surface states,and has led to successful discoveries of novel topological surface states in Chern insulators,topological insulators,and topological Fermi arcs in Weyl,Dirac,and Nodal line semimetals owing to their nontrivial bulk topology.In particular,topological phases in non-Hermitian systems have attracted growing interests in recent years.In this work,we predict the emergence of the topologically stable nodal disks where the real part of the eigen frequency is degenerate between two bands in non-ideal magnetohydrodynamics plasma with collision and viscosity dissipations.Each nodal disk possesses continuously distributed topological surface charge density that integrates to unity.It is found that the lossy Fermi arcs at the interface connect to the middle of the projection of the nodal disks.We further show that the emergence,coalescence,and annihilation of the nodal disks can be controlled by plasma parameters and dissipation terms.Our findings contribute to understanding of the linear theory of bulk and surface wave dispersions of non-ideal warm magnetic plasmas from the perspective of topological physics. | Wenhui Wang Wenlong Gao Leifeng Cao Yuanjiang Xiang Shuang Zhang | 2020 | Light(Science & Applications)2020，9，1： | 0 |
| 18 | Gut microbe-derived metabolite indole-3-carboxaldehyde alleviates atherosclerosis显示文摘DearEditor,Indole-3-carboxaldehyde(ICA)is a gut microbe-derived tryptophan metabolite.Here,we explored the role of ICA in atherosclerosis.Plasma tryptophan metabolites were measured in healthy individuals and patients with atherosclerosis(Supplementary Table S1).The latter group showed disturbed tryptophan metabolism,while no difference was observed in tryptophan levels between the two groups(Fig.1a).ICA concentration is lower in the patients group(Fig.1b),consistent with previous clinical studies.1 The concentration of other metabolites of kynurenine or serotonin pathway showed no variations between the control and the patients(Supplementary Fig.1a). | Yijing Lu Wenlong Yang Zhiyong Qi Rifeng Gao Jing Tong Tingwen Gao Yin Zhang Aijun Sun Shuning Zhang Junbo Ge | 2023 | Signal Transduction and Targeted Therapy2023，8，11： | 0 |
| 19 | Correction: Characterization of a small-molecule inhibitor targeting NEMO/IKKβ to suppress colorectal lcancergrowth显示文摘In the process of collating the raw data,the authors noticed an inadvertent mistake occurred in Fig.3b that needs to be corrected after online publication of the article.In Fig.3b,as a result of an error in the graphics panel arrangement process,the band of NEMO was repeatedly inserted asβ-actin by mistake.The correct band is shown as below and in the updated Fig.3b.The correction did not affect any of our results or discussion as present in the original publication.We regret any inconvenience this has caused. | Zhenlong Yu Jian Gao Xiaolei Zhang Yulin Peng Wenlong Wei Jianrong Xu Zhenwei Li Chao Wang Meirong Zhou Xiangge Tian Lei Feng Xiaokui Huo Min Liu Mingliang Ye De-an Guo Xiaochi Ma | 2023 | Signal Transduction and Targeted Therapy2023，8，10： | 0 |
| 20 | Genome resequencing reveals the evolutionary history of garlic reproduction traits显示文摘The propagation of cultivated garlic relies on vegetative cloves,thus flowers become non-essential for reproduction in this species,driving the evolution of reproductive feature-derived traits.To obtain insights into the evolutionary alteration of reproductive traits in the clonally propagated garlic,the evolutionary histories of two main reproduction-related traits,bolting and flower differentiation,were explored by genome analyses using 134 accessions displaying wide diversity in these two traits.Resequencing identified 272.8 million variations in the garlic genome,198.0million of which represent novel variants.Population analysis identified five garlic groups that have evolved into two clades.Gene expression,single-cell transcriptome sequencing,and genome-wide trait association analyses have identified numerous candidates that correlate with reproductive transition and flower development,some of which display distinct selection signatures.Selective forces acting on the B-box zinc finger protein-encoding Asa2G00291.1,the global transcription factor group E protein-encoding Asa5G01527.1,and VERNALIZATION INSENSITIVE 3-like Asa3G03399.1 appear to be representative of the evolution of garlic bolting.Plenty of novel genomic variations and trait-related candidates represent valuable resources for biological studies of garlic.Numerous selective signatures from genes associated with the two chosen reproductive traits provide important insights into the evolutionary history of reproduction in this clonally propagated crop. | Haiping Wang Einat Shemesh-Mayer Jiangjiang Zhang Song Gao Zheng Zeng Zemao Yang Xueyu Zhang Huixia Jia Yanzhou Wang Jiangping Song Xiaohui Zhang Wenlong Yang Qiaoyun He Amir Sherman Lin Li Rina Kamenetsky Touming Liu | 2023 | Horticulture Research2023，10，11： | 0 |
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