维普中文期刊产品整合服务
97篇 您的检索式:作者名="Xi Lai"
    题名 作者 年代 出处 被引量
1Contemporary crustal movement of continental China obtained by global positioning system(GPS) measurements显示文摘We obtain a unified horizontal velocity field of continental China and vicinity through measurements at 81 GPS stations provided by the National Key Infrastructure Project, Crustal Movement Observation Network of China. The velocity field delineates patterns of movements and deformation of active crustal blocks in continental China under the Eurasia-fixed reference frame. The space-based geodesy also clearly shows for the first time the horizontal movementand deformation of continental China induced by indentation of the Indian plate. The data provide kinematic constraints for simulating dynamic process of continental litho-spheric deformation.MA Zongjin, CHEN Xinlian, YE Shuhua, LAI Xian, WEI Ziqing, CHEN Junrong, NING Jinsheng, XU Huoze & DING Guoyu1. Insitute of Geology, China Seismological Bureau, Beijing 100029, China (e-mail: disgroup@publi.bta.net.cn)2. Center for Analysis and Prediction, China Seismological Bureau, Beijing 100036, China 3. Shanghai Astronomic Observatory, Chinese Academy of Sciences, Shanghai 200030, China 4. Institute of Seismology, China Seismological Bureau, Wuhan 430077, China 5. Institute of Survey and Mapping, Xi’an 710054, China 6. National Bureau of Survey and Mapping, Beijing 100830, China 7. Wuhan University, Wuhan 430077, China 8. Institute of Geodesy and Geophysics, Wuhan 430077, China 9. China Seismological Bureau, Beijing 100036, China 2001Chinese Science Bulletin2001,46,18:34
2Epidemiology of respiratory distress and the illness severity in late preterm or term infants: a prospective multi-center study显示文摘背景呼吸悲痛的严厉与新生的预后被联系。这研究试图近来探索临床的特征,治疗学的干预和短期的结果要求了的 preterm 或术语婴儿呼吸支持,并且比较不同的病严厉评价 tools.Methods 的用法第三级的医院里的七个新生的特别护理单位被招募。从 2008 年 11 月到 2009 年 10 月,在 34 星期的 gestational 出生的出生不满一月的婴儿变老,在 72 小时年龄承认了,为呼吸支持要求连续积极航线压力(CPAP ) 或机械通风被注册。包括人口统计的变量,内在的疾病,复杂并发症,治疗学的干预和短期的结果的临床的数据是镇定的。所有婴儿被在风险新生儿(橡树子) 的尖锐照顾划分成三个组呼吸分数 5, 5-8,和 8 .Results 在学习时期, 503 新生的迟了的 preterm 或学期婴儿期间要求了呼吸支持。吝啬的 gestational 年龄是(36.8 ? 湥牧獯敳 ? 湩 ? 眠吗?MA Xi'ao-lu XU Xue-feng CHEN Chao YAN Chao-ying LIU Ya-ming LIU Ling XIONG Hong SUN Hui-qing LAI Jian-pu YI Bin SHI Jing-yun DU Li-zhong 2010Chinese Medical Journal2010,,20:31
3Geochemical Features of Ophiolite in Mianxian Lueyang Suture Zone,Qinling Orogenic Belt显示文摘GeochemicalFeaturesofOphioliteinMianxianLueyangSutureZone,QinlingOrogenicBeltLaiShaocong;ZhangGuowei(DepartmentofGeology,Nort...Lai Shaocong Zhang Guowei(Department of Geology, Northwest University, Xi’an 710069) 1996Journal of Earth Science1996,15,2:22
4Symmetric-key cryptosystem with DNA technology显示文摘DNA cryptography is a new field which has emerged with progress in the research of DNA computing. In our study, a symmetric-key cryptosystem was designed by applying a modern DNA biotechnology, microarray, into cryptographic technologies. This is referred to as DNA symmetric-key cryptosystem (DNASC). In DNASC, both encryption and decryption keys are formed by DNA probes, while its ciphertext is embedded in a specially designed DNA chip (microarray). The security of this system is mainly rooted in difficult biology processes and problems, rather than conventional computing technology, thus it is unaffected by changes from the attack of the coming quantum computer. The encryption process is a fabrication of a specially designed DNA chip and the decryption process is the DNA hybridization. In DNASC, billions of DNA probes are hybridized and identified at the same time, thus the decryption process is conducted in a massive, parallel way. The great potential in vast parallelism computation and the extraordinary information density of DNA are displayed in DNASC to some degree.LU MingXin1,2*, LAI XueJia3*, XIAO GuoZhen4,2 & QIN Lei5 1 Department of Information Management, Nanjing University, Nanjing 210093, China 2 State Key Lab of Information Security, Institute of Software of Chinese Academy of Science, Beijing 100049, China 3 Department of Computer Science & Engineer, Shanghai Jiao Tong University, Shanghai 200030, China 4 State Key Lab of ISN, Xidian University, Xi’an 710071, China 5 Cancer Research Institute, Queen’s University, Kingston, Ontario, K7L3N6, Canada 2007Science in China(Series F)2007,50,3:14
5TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang 2016Cell Research2016,26,9:13
6CYP11B2 expression in HSCs and its effect on hepatic fibrogenesis显示文摘INTRODUCTIONIt has been reported that renin-angiotensin systemexists in tissue and aldosterone can be synthesizedin extra-adrenal tissue including heart,bloodvessels and brain.Recent studies have broughtrich evidences in favour of aldosterone as a strongstimulator of fibrogenesis and mitogenesis.Xu Li Ying Meng Xi Shan Yang Ping Sheng Wu Shu Mei Li Wen Yan Lai 2000World Journal of Gastroenterology2000,6,6:11
7Clinical and experimental study of effect of Raondix Salviae Militiorhiza and other blood-activating and stasis-eliminating Chinese herbson hemodynamics of portal hypertension显示文摘INTRODUCTIONTherehasbeennolonglastingandsideeffectsfreedrugstolowertheportalhypertensioninpatientswithlivercirrhosissofar.Th...YAO Xi Xian, CUI Dong Lai, SUN Yu Feng and LI Xiao Tian 1998World Journal of Gastroenterology1998,4,5:10
8Timing of carbonatite-hosted U-polymetallic mineralization in the supergiant Huayangchuan deposit,Qinling Orogen:Constraints from titanite U-Pb and molybdenite Re-Os dating显示文摘The newly-discovered supergiant Huayangchuan uranium(U)-polymetallic(Sr,Se,REEs,Ba,Nb and Pb)deposit is located in the Qinling Orogen,central China.The deposit underwent multistage mineralization,with the main carbonatite ore stage being the most important for the U,Nb,REE,Sr and Ba endowments.According to the mineral assemblages,the main carbonatite ore stage can be divided into three substages,i.e.,sulfate(Ba-Sr),alkali-rich U and REE-U mineralization.Main-stage titanite from the Huayangchuan igneous carbonatite are rich in high field strength elements(HFSEs,e.g.,Zr,Nb and REEs),and show clear elemental substitutions(e.g.,Ti vs.Nb+Fe+Al and Ca+Ti vs.Fe+Al+REE).High-precision LA-ICP-MS titanite dating yielded a U-Pb age of 209.0±2.9 Ma,which represents the mainstage mineralization age at Huayangchuan,and is coeval with the local carbonatite dyke intrusion.This mineralization age is further constrained by the Re-Os dating of molybdenite from the Huayangchuan carbonatite,which yielded a weighted mean age of 196.8±2.4 Ma.Molybdenite Re contents(337.55-392.75 ppm)and C-OSr-Nd-Pb isotopic evidence of the Huayangchuan carbonatite both suggest a mantle origin for the carbonatite.Our study supports that the Late Triassic carbonatite magmatism was responsible for the world-class U-Mo-REE mineralization in the Qinling Orogen,and that the regional magmatism and ore formation was likely caused by the closure of the Mianlue ocean and the subsequent North China-South China continent-continent collision.Hui Zheng Huayong Chen Dengfeng Li Chao Wu Xi Chen Chun-kit Lai 2020Geoscience Frontiers2020,11,5:8
9Suppressing secondary reactions of coal pyrolysis by reducing pressure and mounting internals in fixed-bed reactor显示文摘Pyrolysis of Shenmu coal was performed in fixed-bed reactors indirectly heated by reducing operating pressure and mounting internals in the reactor to explore their synergetic effects on coal pyrolysis. Mounting internals particularly designed greatly improved the heat transfer inside coal bed and raised the yield of tar production.Reducing pressure further facilitated the production of tar through its suppression of secondary reactions occurring in the reactor. The absolute increase in tar yield reached 3.33 wt% in comparison with the pyrolysis in the reactor without internals under atmospheric pressure. The obtained tar yield in the reactor with internals under reduced pressure was even higher than the yield of Gray–King assay. Through experiments in a laboratory fixed bed reactor, it was also clarified that the effect of reducing pressure is related to volatile release rate in pyrolysis. It did not obviously vary tar yield at pyrolysis temperatures below 600 °C, while the effect was evident at 650 and 700 °C but became limited again above 800 °C. Under reduced pressure the produced tar contained more aliphatics and phenols but less aromatics.Shuai Cheng Dengguo Lai Zhen Shi Leisheng Hong Jianling Zhang Xi Zeng Shiqiu Gao Guangwen Xu 2017Chinese Journal of Chemical Engineering2017,25,4:7
10Effects of neuregulin-1 on autonomic nervous system remodeling post-myocardial infarction in a rat model显示文摘Sympathetic nerve and vagus nerve remodeling play an important part in cardiac function post-myocardial infarction(MI). Increasing evidence indicates that neuregulin-1(NRG-1) improves cardiac function following heart failure. Since its impact on cardiac function and neural remodeling post-MI is poorly understood, we aimed to investigate the role of NRG-1 in autonomic nervous system remodeling post-MI. Forty-five Sprague-Dawley rats were equally randomized into three groups: sham(with the left anterior descending coronary artery exposed but without ligation), MI(left anterior descending coronary artery ligation), and MI plus NRG-1(left anterior descending coronary artery ligation followed by intraperitoneal injection of NRG-1(10 μg/kg, once daily for 7 days)). At 4 weeks after MI, echocardiography was used to detect the rat cardiac function by measuring the left ventricular end-systolic inner diameter, left ventricular diastolic diameter, left ventricular end-systolic volume, left ventricular end-diastolic volume, left ventricular ejection fraction, and left ventricular fractional shortening. m RNA and protein expression levels of tyrosine hydroxylase, growth associated protein-43(neuronal specific protein), nerve growth factor, choline acetyltransferase(vagus nerve marker), and vesicular acetylcholine transporter(cardiac vagal nerve fiber marker) in ischemic myocardia were detected by real-time PCR and western blot assay to assess autonomous nervous remodeling. After MI, the rat cardiac function deteriorated significantly, and it was significantly improved after NRG-1 injection. Compared with the MI group, m RNA and protein levels of tyrosine hydroxylase and growth associated protein-43, as well as choline acetyltransferase m RNA level significantly decreased in the MI plus NRG-1 group, while m RNA and protein levels of nerve growth factor and vesicular acetylcholine transporters, as well as choline acetyltransferase protein level slightly decreased. Our results indicate that NRG-1 can improve cardiac function and regulate sympathetic and vagus nerve remodeling post-MI, thus reaching a new balance of the autonomic nervous system to protect the heart from injury.Xin Lai Liang Zhong Hai-xia Fu Song Dang Xin Wang Ning Zhang Gao-ke Feng Zi-qiang Liu Xi Wang Long Wang 2017Neural Regeneration Research2017,12,11:7
11Maternal exposure to triclosan constitutes a yet unrecognized risk factor for autism spectrum disorders显示文摘Dear Editor,Autism spectrum disorders(ASD)are complex neurodevelopmental disorders characteristic of core behavioral traits like restricted,repetitive behaviors and deficiency in social interactions.1 The prevalence of ASD has rapidly increased worldwide,rising from 1/149 in 2000,1/68 in 2012,and to?1/40 in 2016 of children at the age of 3-17 in the United States.2 ASD prevalence was found to be associated with socioeconomic status(SES)as overpresented in high-income households,3 and to be significantly enriched in certain regions,e.g.,reaching up to 4.88%in Florida.2 In the last decades,advances in genetic studies have led to unprecedented understanding of the genetic factors that were associated with<50%of human ASD.Zijian Hao Qionghui Wu Zhengwei Li Yali Li Qiu Li Xi Lai Huan Liu Menghuan Zhang Ting Yang Jie Chen Yaping Tang Jingkun Miao Huatai Xu Tingyu Li Ronggui Hu 2019Cell Research2019,29,10:5
12Diagnosis of Early Esophageal Cancer Based on TCM Tongue Inspection显示文摘Esophageal cancer is a common malignant carcinoma that occurs in the digestive tract and leads to around three million deaths worldwide.Patients commonly present with symptoms,such as dysphagia,cough,hoarseness,and pain in the esophagus.According to researches,smoking,alcohol consumption,exposure to radiation,contaminated food,chronic throat irritation,consumption of extremely hot beverages,genetic mutation,and dystrophia are influential factors in the development of esophageal carcinoma[1].SONG An Yi LOU Yan Ni YANG Qian Xi LI Dong Fang SONG Guo Hui HUANG Lai Qiang YUAN Ke Hong JIA Li Qun 2020Biomedical and Environmental Sciences2020,33,9:5
13Clinical application of a novel sliver nanoparticles biosensor based on localized surface plasmon resonance for detecting the microalbuminuria显示文摘以便基于局部性的表面电浆子回声(LSPR ) 探索 nanobiosensor 的临床的申请,我们使用了我们的 LSPR 生物传感器在这个工作检测 microalbuminuria。裂片 nanoparticles 被使用 nanosphere 平版印刷术制作。反人的白朊抗体被联合方法的胺在传感器表面上使不能调动。在从三个温和 preeclampsia 病人的尿样品的商业白朊和白朊的不同集中根据 LSPR 扑灭系列的山峰被决定。在最佳条件下面,我们的结果证明生物传感器显示了 1 ng/ml 的察觉限制和 1 ng/ml 的宽动态范围到 1 g/ml。而且,三个病人的 microalbuminuria 被我们的生物传感器在一短试金时间以内决定,没有样品纯化。此处建议的这个生物传感器是容易的准备并且能被用于便宜、快速、没有标签、敏感 microalbuminuria 屏蔽。这条途径为开发临床的诊断应用程序提供一个有希望的平台。Ting Lai Qiannan Hou Huan Yang Xiangang Luo Mingrong Xi 2010Acta Biochimica et Biophysica Sinica2010,42,11:4
14Exposure to PM2.5 Enhances the PI3K/AKT Signaling and Malignancy of ERα Expression-dependent Non-small Cell Lung Carcinoma显示文摘Atmospheric particulate matter(PM)2.5 is a major carcinogen and is associated with an increased risk of developing various cancers and pulmonary fibrous diseases[1-2].Non-small cell lung cancer(NSCLC)is the major type of lung cancer with high morbidity and mortality rates.Epidemiological studies report that the incidence of NSCLC,particularly adenocarcinoma,significantly differs with the gender[3].Female patients with NSCLC have unique epidemiologic characteristics,imaging profiles,clinical manifestations,and pathological characteristics[4].TIAN Lei LI Ying LIU Huan Liang LAI Wen Qing SHI Yue LIU Xiao Hua XI Zhu Ge LIN Ben Cheng 2021Biomedical and Environmental Sciences2021,34,4:3
15POLYNOMIAL MODEL BASED FAST FRACTIONAL PIXEL SEARCH ALGORITHM FOR H.264/AVC显示文摘This paper proposed a novel fast fractional pixel search algorithm based on polynomial model. With the analysis of distribution characteristics of motion compensation error surface inside fractional pixel searching window, the matching error is fitted with parabola along horizontal and vertical direction respec-tively. The proposed searching strategy needs to check only 6 points rather than 16 or 24 points, which are used in the Hierarchical Fractional Pel Search algorithm (HFPS) for 1/4-pel and 1/8-pel Motion Estimation (ME). The experimental results show that the proposed algorithm shows very good capability in keeping the rate distortion performance while reduces computation load to a large extent compared with HFPS algorithm.Xi Yinglai Hao Chongyang Lai Changcai 2006Journal of Electronics(China)2006,23,6:3
16Rescue of male infertility through correcting a genetic mutation causing meiotic arrest in spermatogonial stem cells显示文摘Azoospermia patients who carry a monogenetic mutation that causes meiotic arrest may have their biological child through genetic correction in spermatogonial stem cells(SSCs).However,such therapy for infertility has not been experimentally investigated yet.In this study,a mouse model with an X-linked testis-expressed 11(TEX11)mutation(Tex11PM/Y)identified in azoospermia patients exhibited meiotic arrest due to aberrant chromosome segregation.Tex11PM/Y SSCs could be isolated and expanded in vitro normally,and the mutation was corrected by clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated endonuclease 9(Cas9),leading to the generation of repaired SSC lines.Whole-genome sequencing demonstrated that the mutation rate in repaired SSCs is comparable with that of autonomous mutation in untreated Tex11PM/Y SSCs,and no predicted off-target sites are modified.Repaired SSCs could restore spermatogenesis in infertile males and give rise to fertile offspring at a high efficiency.In summary,our study establishes a paradigm for the treatment of male azoospermia by combining in vitro expansion of SSCs and gene therapy.Ying-Hua Wang Meng Yan Xi Zhang Xin-Yu Liu Yi-Fu Ding Chong-Ping Lai Ming-Han Tong Jin-Song Li 2021Asian Journal of Andrology2021,23,6:3
17Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease显示文摘瞄准:低剂量的阿司匹林的使用很好被建立阻止心血管的疾病事件。然而,上面的胃肠的流血的发生和有它的使用的预言者(UGIB ) 是未知的。我们有希望地在低剂量的阿司匹林用户学习了消化剂溃疡的发生和结果。方法:有低剂量的阿司匹林上的冠的动脉疾病(CAD ) 的 991 个病人的一个总数是有希望地跟随起来的为出现和 UGIB 的首先就医的事件的临床的特征的二年了。结果:UGIB 有一个双性人有 45% 发生在四月阿司匹林开始以内的形式的表示并且每年有 1.5% 的全面流行。没有 UGIB 相关的死亡。高血压(或= 4.6 , 95%CI 1.5-14.7 , P = 0.009 ),消化剂溃疡的历史(或= 3.1 , 95%CI 1.1-9.0 , P = 0.039 ),第三级的教育(或= 3.08 , 95%CI 1.1-9.0 , P = 0.039 )并且更高瘦的身体质量( P = 0.016 )独立因素与 UGIB 被联系。硝酸盐的使用没减少 UGIB。结论:在有长期的低剂量的阿司匹林上的 CAD 的病人的 UGIB 的发生是低的,但是伴有重要病态。与阿司匹林的延长使用, UGIB 继续是为有风险因素并且特别在有消化性溃疡, UGIB 在趋于在阿司匹林治疗以后早发生的历史的病人的那些的一个问题。William Ng Wai-Man Wong Wai-Hong Chen Hung-Fat Tse Pui-Yin Lee Kam-Chuen Lai Sheung-Wai Li Matthew Ng Kwok-Fai Lam Xi Cheng Chu-Pak Lau 2006World Journal of Gastroenterology2006,12,18:3
18Pyrolysis characteristics of waste tire particles in fixed-bed reactor with internals显示文摘This study investigated the characteristics of pyrolysis for waste tire particles in the newly developed fixed-bed reactor with internals that are a central gas collection channel mounted inside reactor.And a few metallic plates vertically welded on the internal wall of the reactors and extending to the region closing their central gas collection pipe walls.Experiments were conducted in two laboratory fixed bed reactors with or without the internals.The results shown that employing internals produced more light oil at externally heating temperatures above 700℃due to the inhibited secondary reactions in the reactor.The oil from the reactor with internals contained more aliphatic hydrocarbons and fewer aromatic hydrocarbons,leading to its higher H/C atomic ratios as for crude petroleum oil.The char yield was relatively stable for two beds and showed the higher heating values(HHVs)of about 23 MJ/kg.The gaseous product of pyrolysis mainly consisted of H2 and CH4,but the use of internals led to less pyrolysis gas through its promotion of oil production.Shipei Xu Dengguo Lai Xi Zeng Lijuan Zhang Zhennan Han Jiguang Cheng Rongcheng Wu Ondřej Mašek Guangwen Xu 2018Carbon Resources Conversion2018,1,3:3
19Endoscopic ultrasound features of autoimmune pancreatitis: The typical findings and chronic pancreatitis changes显示文摘BACKGROUND Few studies have fully described endoscopic ultrasound(EUS)features of newly diagnosed autoimmune pancreatitis(AIP)involving both typical findings and chronic pancreatitis(CP)features.The typical EUS findings are prevalent in the diffuse type AIP but may not be as common for the focal type,and the differences between the diffuse and focal AIP need to be specified.AIM To demonstrate the EUS features of newly diagnosed AIP and the difference between diffuse and focal AIP.METHODS This retrospective single center study included 285 patients of newly diagnosed type 1 AIP following the international consensus diagnostic criteria,with the EUS procedures accomplished before corticosteroid initiation.We explored the EUS features and compared the typical AIP and CP features between the diffuse and focal AIP cases.The Rosemont criteria were employed for CP features definition and CP change level comparison.RESULTS For the typical AIP features,there were significantly more patients in the diffuse group with bile duct wall thickening(158 of 214 cases,73.4%vs 37 of 71 cases,52.1%,P=0.001)and peripancreatic hypoechoic margin(76 of 214 cases,35.5%vs 5 of 71 cases,7.0%,P<0.001).For the CP features,there were significantly more patients in the focal group with main pancreatic duct dilation(30 of 214 cases,14.0%vs 18 of 71 cases,25.3%,P=0.03).The cholangitis-like changes were more prevalent in the focal cases with pancreatic head involvement.The CP change level was relatively limited for newly diagnosed AIP cases in both groups.CONCLUSION This study demonstrated the difference in the typical AIP and CP features between diffuse and focal AIP and indicated the limited CP change level in newly diagnosed AIP.Sheng-Yu Zhang Yun-Lu Feng Long Zou Xi Wu Tao Guo Qing-Wei Jiang Qiang Wang Ya-Min Lai Shou-Jiang Tang Ai-Ming Yang 2021World Journal of Gastroenterology2021,27,42:2
20Influence of heat treatment on interface of Cu/Al bimetal composite fabricated by cold rolling显示文摘L.Y. Sheng F. Yang T.F. Xi C. Lai H.Q. Ye 2011Composites Part B2011,,6:2
返回顶部 每页显示:
共5页 首页 上一页 第1页 下一页 末页 /5 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费