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| 1 | Analysis of key microbial community during the start-up of anaerobic ammonium oxidation process with paddy soil as inoculated sludge显示文摘A sequencing batch reactor(SBR)-anaerobic ammonium oxidation(anammox) system was started up with the paddy soil as inoculated sludge. The key microbial community structure in the system along with the enrichment time was investigated by using molecular biology methods(e.g., high-throughput 16 S r RNA gene sequencing and quantitative PCR). Meanwhile,the influent and effluent water quality was continuously monitored during the whole start-up stage. The results showed that the microbial diversity decreased as the operation time initially and increased afterwards, and the microbial niches in the system were redistributed. The anammox bacterial community structure in the SBR-anammox system shifted during the enrichment, the most dominant anammox bacteria were Candidatus Jettenia. The maximum biomass of anammox bacteria achieved 1.68 × 10~9 copies/g dry sludge during the enrichment period, and the highest removal rate of TN achieved around 75%. | Xianglong Xu Guohua Liu Yuanyuan Wang Yuankai Zhang Hao Wan Lu Qi Hongchen Wang | 2018 | Journal of Environmental Sciences2018，30，2： | 8 |
| 2 | ZBP1(DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling显示文摘The lineage specification of mesenchymal stem/stromal cells(MSCs) is tightly regulated by a wide range of factors. Recently, the versatile functions of ZBP1(also known as DAI or DLM-1) have been reported in the blood circulation and immune systems.However, the biological function of ZBP1 during the lineage specification of MSCs is still unknown. In the present study, we found that ZBP1 was upregulated during osteogenesis but downregulated during adipogenesis in mouse bone marrow-derived MSCs(m BMSCs). ZBP1 was highly expressed in osteoblasts but expressed at a relatively low level in marrow adipocytes. Knockdown of ZBP1 inhibited alkaline phosphataseactivity, extracellular matrix mineralization, and osteogenesis-related gene expression in vitro and reduced ectopic bone formation in vivo. Knockdown of ZBP1 also promoted adipogenesis in MSCs in vitro. Conversely, the overexpression of ZBP1 increased the osteogenesis but suppressed the adipogenesis of MSCs. When the expression of ZBP1 was rescued, the osteogenic capacity of ZBP1-depleted m BMSCs was restored at both the molecular and phenotypic levels.Furthermore, we demonstrated that ZBP1, a newly identified target of Wnt/β-catenin signaling, was required for β-catenin translocation into nuclei. Collectively, our results indicate that ZBP1 is a novel regulator of bone and fat transdifferentiation via Wnt/β-catenin signaling. | Xuefeng Zhao Liang Xie Zhiyong Wang Jiongke Wang Hao Xu Xianglong Han Ding Bai Peng Deng | 2020 | Bone Research2020，8，2： | 8 |
| 3 | Scale-up of a high shear wet granulation process using a nucleation regime map approach显示文摘 | Gan Luo Bing Xu Yi Zhang Xianglong Cui Jianyu Li Xinyuan Shi Yanjiang Qiao | 2017 | Particuology2017，15，2： | 7 |
| 4 | The existence of propagated sensation along the meridian proved by neuroelectrophysiology显示文摘Propagated sensation along the meridian can occur when acupoints are stimulated by acupuncture or electrical impulses.In this study,participants with notable propagated sensation along the meridian were given electro-acupuncture at the Jianyu(LI15)acupoint of the large intestine meridian.When participants stated that the sensation reached the back of their hand,regular nervous system action discharge was examined using a physiological recording electrode placed on the superficial branch of the radial nerve.The topographical maps of brain-evoked potential in the primary cortical somatosensory area were also detected.When Guangming(GB37)acupoint in the lower limb and Hegu(LI4)acupoint in the upper limb were stimulated,subjects without propagated sensation along the meridian exhibited a high potential reaction in the corresponding area of the brain cortical somatosensory area.For subjects with a notable propagated sensation along the meridian,the reaction area was larger and extended into the face representative area.These electrophysiological measures directly prove the existence of propagated sensation along the meridian,and the peripheral stimulated site is consistent with the corresponding primary cortical somatosensory area,which presents a high potential reaction. | Jinsen Xu Shuxia Zheng Xiaohua Pan Xiaoxiang Zhu Xianglong Hu | 2013 | Neural Regeneration Research2013，8，28： | 7 |
| 5 | Do migrant and resident species differ in the timing of increases in reproductive and thyroid hormone secretion and body mass? A case study in the comparison of pre-breeding physiological rhythms in the Eurasian Skylark and Asian Short-toed Lark显示文摘Background:Physiological preparation for reproduction in small passerines involves the increased secretion of reproductive hormones, elevation of the metabolic rate and energy storage, all of which are essential for reproduction. However, it is unclear whether the timing of the physiological processes involved is the same in resident and migrant species that breed in the same area. To answer this question, we compared temporal variation in the plasma concentration of luteinizing hormone(LH), testosterone(T), estradiol(E_2), triiothyronine(T_3) and body mass, between a migrant species, the Eurasian Skylark(Alauda arvensis) and a resident species, the Asian Short-toed Lark(Calandrella cheleensis), both of which breed in northeastern Inner Mongolia, China, during the 2014 and 2015 breeding seasons.Methods:Twenty adult Eurasian Skylarks and twenty Asian Short-toed Larks were captured on March 15, 2014 and 2015 and housed in out-door aviaries. Plasma LH, T(males), E_2(females), T_3 and the body mass of each bird were measured every six days from March 25 to May 6.Results:With the exception of T, which peaked earlier in the Asian Short-toed Lark in 2014, plasma concentrations of LH, T, E_2 and T_3 of both species peaked at almost the same time. However, Asian Short-toed Larks attained peak body mass earlier than Eurasian Skylarks. Plasma T_3 concentrations peaked 12 days earlier than plasma LH in both species. Generally, plasma LH, T, E_2, T_3 and body mass, peaked earlier in both species in 2014 than 2015.Conclusions:The timing of pre-reproductive changes in the endocrine system and energy metabolism can be the same in migrant and resident species; however, residents may accumulate energy reserves faster than migrants. Although migration does not affect the timing of pre-breeding reproductive and metabolic changes, migrant species may need more time to increase their body mass. T levels in resident species may be accelerated by higher spring temperatures that may also advance the pre-breeding preparation of both migrants and residents. | Lidan Zhao Lijun Gao Wenyu Yang Xianglong Xu Weiwei Wang Wei Liang Shuping Zhang | 2017 | Avian Research2017，8，2： | 4 |
| 6 | Formation mechanism of propagated sensation along the meridians,as verified by cortical somatosensory-evoked potential topographic maps显示文摘The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture;the driver provokes nerve sense devices along the meridian,resulting in the nerve impulse entering the central nervous system.Accordingly,volunteers have reported propagated sensations along the meridians (PSM).The present study was designed to utilize a cortical somatosensory-evoked potential (CSEP) topographic map for determining whether stimulation expansion occurs in somatosensory area I when sensation was provoked in individuals with obvious PSM.The sensation was blocked by mechanical compression,and the sensation was imitated in individuals without PSM.Results revealed a red,high-potential signal in the representative area of the lower limbs in individuals with obvious PSM symptoms when the Gall Bladder Meridian (GBM) sensation passed to the head and face.This representative area was near the middle line of the CSEP topographic map,and a red,high-potential signal,which jumps over the representative area of the upper limbs,also appeared in the representative face area,which was at the external region of the CSEP topographic map.However,in individuals exhibiting no PSM,only a red high-potential signal appeared in the representative lower limb area.When Hegu (LI 4) was stimulated in individuals without PSM,an obvious evoked response appeared only in the representative upper limb area.However,when Hegu was stimulated in individuals exhibiting PSM,the response area was larger in the representative upper limb area and extended to the representative face area.When Guangming (GB 37) was stimulated in PSM individuals,the face representation response disappeared and was confined to a foot representation of the somatosensory area I when PSM was blocked by mechanical pressure.Results suggested that mechanical compression blocked PSM,and corresponding changes were exhibited in the CSEP topographic map.These results provide compelling evidence for the hypothesis that peripheral driver stimulation is the key element in producing PSM. | Jinsen Xu Xiaohua Pan Shuxia Zheng Xianglong Hu Zheyan Sa | 2011 | Neural Regeneration Research2011，6，6： | 3 |
| 7 | Ecological selection of bacterial taxa with larger genome sizes in response to polycyclic aromatic hydrocarbons stress显示文摘Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous priority pollutants that cause great damage to the natural environment and health.Average genome size in a community is critical for shedding light on microbiome's functional response to pollution stress within an environment.Here,microcosms under different concentrations were performed to evaluate the selection of PAHs stress on the average genome size in a community.We found the distinct communities of significantly larger genome size with the increase of PAHs concentration gradients in soils,and consistent trends were discovered in soils at different latitudes.The abundance of Proteobacteria and Deinococcus-Thermus with relatively larger genomes increased along with PAHs stress and well adapted to polluted environments.In contrast,the abundance of Patescibacteria with a highly streamlined and smaller genome decreased,implying complex interactions between environmental selection and functional fitness resulted in bacteria with larger genomes becoming more abundant.Moreover,we confirmed the increased capacity for horizontal transfer of degrading genes between communities by showing an increased connection number per node positively related to the nid A gene along the concentration gradients in the co-occurrence network.Our findings suggest PAHs tend to select bacterial taxa with larger genome sizes,with significant consequences for community stability and potential biodegradation strategies. | Yuzhu Dong Shanghua Wu Haonan Fan Xianglong Li Yijing Li Shengjun Xu Zhihui Bai Xuliang Zhuang | 2022 | Journal of Environmental Sciences2022，34，2： | 2 |
| 8 | Surfacemodification of nano-alumina and its application in preparingpolyacrylate water-based wood coating 显示文摘 | Ling Long Jianfeng Xu Xianglong Wan | 2013 | Journal of PolymerEngineering2013，33，8： | 1 |
| 9 | Genome sequence of Gossypium anomalum facilitates interspecific introgression breeding显示文摘Crop wild relatives are an important reservoir of natural biodiversity. However, incorporating wild geneticdiversity into breeding programs is often hampered by reproductive barriers and a lack of accurate genomicinformation. We assembled a high-quality, accurately centromere-anchored genome of Gossypium anomalum, a stress-tolerant wild cotton species. We provided a strategy to discover and transfer agronomicallyvaluable genes from wild diploid species to tetraploid cotton cultivars. With a (Gossypium hirsutum 3 G.anomalum)2 hexaploid as a bridge parent, we developed a set of 74 diploid chromosome segment substitution lines (CSSLs) of the wild cotton species G. anomalum in the G. hirsutum background. This set of CSSLsincluded 70 homozygous substitutions and four heterozygous substitutions, and it collectively containedabout 72.22% of the G. anomalum genome. Twenty-four quantitative trait loci associated with plant height,yield, and fiber qualities were detected on 15 substitution segments. Integrating the reference genome withagronomic trait evaluation of the CSSLs enabled location and cloning of two G. anomalum genes thatencode peroxiredoxin and putative callose synthase 8, respectively, conferring drought tolerance andimproving fiber strength. We have demonstrated the power of a high-quality wild-species reference genomefor identifying agronomically valuable alleles to facilitate interspecific introgression breeding in crops. | Zhenzhen Xu Jiedan Chen Shan Meng Peng Xu Caijiao Zhai Fang Huang Qi Guo Liang Zhao Yonggang Quan Yixin Shangguan Zhuang Meng Tian Wen Ya Zhang Xianggui Zhang Jun Zhao Jianwen Xu Jianguang Liu Jin Gao Wanchao Ni Xianglong Chen Wei Ji Nanyi Wang Xiaoxi Lu Shihong Wang Kai Wang Tianzhen Zhang Xinlian Shen | 2022 | Plant Communications2022，3，5： | 1 |
| 10 | Uncertainty Visualisation of a 3D Geological Geometry Model and Its Application in GIS-Based Mineral Resource Assessment:A Case Study in Huayuan District,Northwestern Hunan Province,China显示文摘This paper reports an application of uncertainty visualisation of a regional scale(1:50000)3 D geological geometry model to be involved in GIS-based 3 D mineral potential assessment of the Xiangxibei lead-zinc mineral concentration area in northwestern Hunan District,China.Three-dimensional(3 D)geological modelling is a process of interpretation that combines a set of input measurements in geometry.Today,technology has become a necessary part of GIS-based deep prospecting.However,issues of sparse data and imperfect understanding exist in the process so that there are several uncertainties in 3 D geological modelling.And these uncertainties are inevitably transmitted into the post-processing applications,such as model-based mineral resource assessment.Thus,in this paper,first,a big-data-based method was used to estimate the uncertainty of a 3 D geological model;second,a group of expectations of geological geometry uncertainty were calculated and integrated into ore-bearing stratoisohypse modelling,which is one of the major favourable parameters of assessment for Lead-Zinc(Pb-Zn)deep prospectivity mapping in northwestern Hunan;and finally,prospecting targets were improved. | Nan Li Cangbai Li Wenkai Chu Keyan Xiao Weihan Tao Xianglong Song Rui Cao Yang Xu Mingjing Fan | 2021 | Journal of Earth Science2021，32，2： | 1 |
| 11 | Quantification on the Effects of Liquid-Vapor Separation in Air-Conditioning System by using Advanced Exergy Analysis显示文摘Air-conditioning system consumes a large amount of electricity in residential sections,and its efficiency has drawn extensive concerns in energy-conscious era.Liquid-vapor separation is a heat transfer enhancement technology that can effectively improve the performance of the heat exchanger as well as the system.In this paper,a regular air-conditioning system as the baseline(system-A)and other two air-conditioning systems with liquid-vapor separation heat exchanger(system-B and system-C)are comparatively studied.The component behaviors and system performances are deeply explored by using advanced exergy analysis with a focus on quantifying how much consequences come from the variants,i.e.liquid-vapor separation.The results indicate that the system-B has large reduced exergy destruction from the compressor and condenser at cooling mode relative to the system-A.The system-C has mainly diminished exergy destruction in the compressor caused by other components relative to the system-B.At heating mode,the system-C has an enhanced system exergy efficiency of 9.6%over the system-A,and it also has the decreased avoidable exergy destruction which is dominantly contributed by the compressor and evaporator.Furthermore,it is found that liquid-vapor separation mainly benefits the compressor and outdoor heat exchanger where it locates,leading to the system performance improvements. | LI Yunhai CHEN Jianyong LIN Xu YANG Zhi CHEN Ying LUO Xianglong | 2020 | Journal of Thermal Science2020，29，3： | 1 |
| 12 | Using stable isotope to compare the habitat use and trophie level between the new and old breeding range of wild Crested Ibis in the early breeding season显示文摘The concept of foraging niche provides an insight into habitat use and dietary information of animals.Knowing intraspecific variation in foraging niche and trophic level is critical to the understanding of the species response to environmental changes during the process of range expansion,as well as the habitat management for conservation of threatened species.Using stable isotopic values of eggshell membranes(δ;C andδ;N),we examined whether there are differences in habitat use,trophic level,foraging niche width between the new and old breeding habitats(plains vs.mountains)of wild Crested Ibis(Nipponia nippon)in the early breeding season.Crested Ibis exhibited high variability in bothδ;C andδ;N values,δ;C andδ;N varied as a function of habitat types.Birds breeding in plains had significantly higherδ;C but lowerδ;N values compared to the birds breeding in mountains.Higherδ;N suggested that individuals in mountains consumed a great proportion of higher trophic level prey species in the early breeding season.Moreover,the isotopic niches were distinctly different in positions and showed small overlap between the two habitat types.The niche width was wider in old habitat than in the expanded new habitat.Our results demonstrated that the wild Crested Ibis had a high intraspecific variation in habitat uses and trophic levels in the early breeding season,and they could be divided into mountain and plain groups based on their different foraging niches.The difference inδ;N and niche width revealed that high trophic level food resources might be insufficient in plains.These findings stressed the importance of protecting foraging grounds in mountains and the necessity of improving foraging grounds in plains during winter and spring.Our study highlights the feasibility of investigating intraspecific variation in foraging ecology of birds through non-invasive isotopes of eggshell membranes.Understanding foraging niche variation gives us an insight into the food resource diversity in local areas and provides important information regarding particular foraging habitats that require protection. | Xianglong Xu Jiahu Jiang Yu Lei Chao Wang Baoping Qing Changqing Ding | 2022 | Avian Research2022，13，2： | 1 |
| 13 | Space advanced technology demonstration satellite显示文摘The Space Advanced Technology demonstration satellite(SATech-01),a mission for low-cost space science and new technology experiments,organized by Chinese Academy of Sciences(CAS),was successfully launched into a Sun-synchronous orbit at an altitude of~500 km on July 27,2022,from the Jiuquan Satellite Launch Centre.Serving as an experimental platform for space science exploration and the demonstration of advanced common technologies in orbit,SATech-01 is equipped with 16 experimental payloads,including the solar upper transition region imager(SUTRI),the lobster eye imager for astronomy(LEIA),the high energy burst searcher(HEBS),and a High Precision Magnetic Field Measurement System based on a CPT Magnetometer(CPT).It also incorporates an imager with freeform optics,an integrated thermal imaging sensor,and a multi-functional integrated imager,etc.This paper provides an overview of SATech-01,including a technical description of the satellite and its scientific payloads,along with their on-orbit performance. | ZHANG XiaoFeng CHEN Wen ZHU XiaoCheng MENG Na HE JunWang BI XingZi ZHANG YongHe SHI Qi LI Fei LIU Rui FENG ZhengGong LIU Liu LI JinSong WU HaiChen XU DongXiao LI TaiJie HUANG JiangJiang LIU Shuo LI TianTong YU XianSheng GAO Yang ZHOU Heng BAN HanYu ZHANG YanLi ZHANG YueTing YANG YingQuan HE Tao DUAN XuLiang CHEN Xin WANG YaMin SUN AnTai ZHANG KuoXiang SUN Ying WANG YaoBin FAN ChengCheng XIONG ShaoLin LI XinQiao WEN XiangYang LING ZhiXing SUN XiaoJin ZHANG Chen BAI XianYong WANG ZhanShan DENG YuanYong TIAN Hui YANG JianFeng XUE HongBo SANG Peng LIU JinGuo ZHENG HuiLong ZHU Xiang HE JianWu LI Hui XU LuXiang XU ShuYan CHEN WenWu LIU ZhenDong WANG ZhaoLi MAO XiangLong GAO Rong LI ZongXuan DING GuoPeng WANG XinYu DOU RunJiang WENG LuBin LUO Hao WANG YaPing LIANG XianFeng FANG ZiRuo | 2024 | Science China(Technological Sciences)2024，67，1： | 0 |
| 14 | Research progress of large size SiC single crystal materials and devices显示文摘SiC semiconductor is the focus of recent international research.It is also an important raw material for China to achieve carbon emission peak and carbon neutrality.After nearly 20 years of research and development,we focus on the three types SiC crystals,n-type,p-type and semi-insulating,indicating the development of Shandong University for crystal growth.And defects control,electrical property,atomic polishing,and corresponding device authentication all obtain great progress.Total dislocation density of 6-inch n-type substrates decreases to 2307 cm^(-2),where BPD(Basal Plane Dislocation)lowers to 333 cm^(-2) and TSD(Threading Screw Dislocation)19 cm^(-2).The full width at half maximum(FWHM)(0004)rocking curves is only 14.4 arcsec.The resistivity reaches more than 1E+12Ω·cm for semi-insulating SiC and lower than 20 mΩ·cm for n-type SiC.The impurity concentrations in 6-inch high-purity semi-insulating(HPSI)SiC crystals reach extreme low levels.The devices made of various substrate materials have good performance. | Xiufang Chen Xianglong Yang Xuejian Xie Yan Peng Longfei Xiao Chen Shao Huadong Li Xiaobo Hu Xiangang Xu | 2023 | Light(Science & Applications)2023，12，1： | 0 |
| 15 | Economic Burden of Malignant Tumors——Yichang City,Hubei Province,China,2019显示文摘Summary What is already known about this topic?Malignant tumors are common chronic noncommunicable disease and have caused serious health hazards to residents and heavy economic burden of disease to the society.What is added by this report?This is the first report on the economic burden of multiple types of malignant tumors in Yichang City.In 2019,the direct medical burden of lung cancer in Yichang was the highest,reaching 561.67 million CNY,and the indirect economic burden of lung cancer in Yichang was higher than that of other malignant tumors,costing 326.49 million CNY. | Xiaojuan Long Fangfang Lu Xianglong Xiang Jiajuan Yang Chengzhong Xu Pei Zhang Shicheng Yu Qiqi Wang Chi Hu | 2022 | China CDC weekly2022，4，15： | 0 |
| 16 | Multimodal Spatiotemporal Feature Map for Dynamic Gesture Recognition显示文摘Gesture recognition technology enables machines to read human gestures and has significant application prospects in the fields of human-computer interaction and sign language translation.Existing researches usually use convolutional neural networks to extract features directly from raw gesture data for gesture recognition,but the networks are affected by much interference information in the input data and thus fit to some unimportant features.In this paper,we proposed a novel method for encoding spatio-temporal information,which can enhance the key features required for gesture recognition,such as shape,structure,contour,position and hand motion of gestures,thereby improving the accuracy of gesture recognition.This encoding method can encode arbitrarily multiple frames of gesture data into a single frame of the spatio-temporal feature map and use the spatio-temporal feature map as the input to the neural network.This can guide the model to fit important features while avoiding the use of complex recurrent network structures to extract temporal features.In addition,we designed two sub-networks and trained the model using a sub-network pre-training strategy that trains the sub-networks first and then the entire network,so as to avoid the subnetworks focusing too much on the information of a single category feature and being overly influenced by each other’s features.Experimental results on two public gesture datasets show that the proposed spatio-temporal information encoding method achieves advanced accuracy. | Xiaorui Zhang Xianglong Zeng Wei Sun Yongjun Ren Tong Xu | 2023 | Computer Systems Science & Engineering2023，46，7： | 0 |
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