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| 1 | Generation of induced pluripotent stem cells from human β-thalassemia fibroblast cells显示文摘 | Yixuan Wang Yonghua Jiang Sheng Liu Xiaofang Sun Shaorong Gao | 2009 | Cell Research2009，19，9： | 16 |
| 2 | Optical analysis of a hybrid solar concentrating Photovoltaic /Thermal (CPV/T) system with beam splitting technique显示文摘A novel hybrid solar concentrating Photovoltaic/Thermal (CPV/T) system with beam splitting technique is presented. In this system, a beam splitter is used to separate the concentrated solar radiation into two parts: one for the PV power generation and the other for thermal utility. The solar concentrator is a flat Fresnel-type concentrator with glass mirror reflectors. It can concentrate solar radiation onto solar cells with high uniformity, which is beneficial to improving the efficiency of solar cells. The thermal receiver is separated to the solar cells, and therefore, the thermal fluid can be heated to a relatively high temperature and does not affect the performance of solar cells. A dimensionless model was developed for the performance analysis of the concentrating system. The effects of the main parameters on the performance of the concentrator were analyzed. The beam splitter with coating materials Nb2O3 /SiO2 was designed by using the needle optimization technique, which can reflect about 71% of the undesired radiation for silicon cell(1.1m < 3m) to the thermal receiver for thermal utility. The performance of this CPV/T system was also theoretically analyzed. | HU Peng ZHANG Qian LIU Yang SHENG ChunChen CHENG XiaoFang CHEN ZeShao | 2013 | Science China(Technological Sciences)2013，56，6： | 10 |
| 3 | Adsorption capacity of hydrophobic SiO_2 aerogel/activated carbon composite materials for TNT显示文摘The adsorption properties of TNT from wastewater by hydrophobic silica aerogel/activated carbon composite materials were investigated. The effects of adsorption time, pH value, adsorption temperature, and the amount of the composite materials on the adsorption rate were studied. The adsorption principle and mechanism of the composite materials were discussed along with the Freundlich equation. The results showed that the best adsorption rate of the hydrophobic silica aerogel/activated car-bon composite materials could reach 96.5% with adsorption conditions of adsorption temperature 25°C, pH value 7, the amount of SiO2aerogel dosage 3.33 g/L, and adsorption time of 120 min. The adsorption of hydrophobic SiO2aero-gel/activated carbon composite materials for TNT solution is mainly surface adsorption, and also has some chemical adsorp-tion when the aerogel hydrophobicity is modified. | ZHOU XiaoFang CUI Sheng LIU Yu LIU XueYong SHEN XiaoDong WU ZhanWu | 2013 | Science China(Technological Sciences)2013，56，7： | 5 |
| 4 | Dataset of the plasma membrane proteome of nasopharyngeal carcinoma cell line HNE1 for uncovering protein function显示文摘鼻咽的癌(NPC ) 是在南部的中国和东南亚洲的一个通常发生的肿瘤。当前的学习集中了于为 NPC 房间线 HNE1 的外部、不可分的蛋白质开发一个广泛的分析方法。外部膜蛋白质被 biotinylated 丰富提取, 0.1 M Na 2 公司 3, 和 H 2 O。不可分或全部的血浆膜部分用 30% Percoll 密度等级 centrifugation 被准备与或没有 0.1 M Na 2 公司 3 处理并且由西方的污点分析评估了。蛋白质受到与双人脚踏车团 spectrometry,与双人脚踏车团 spectrometry 相结合的钠 dodecyl sulfate-polyacrylamide 胶化电气泳动,和猎枪分析相结合的二维的电气泳动。我们分别地从外部、不可分、全部的血浆膜部分识别了 371, 180,和 702 蛋白质。总共, 848 非冗余的蛋白质(534 个组) 被识别。有约束力、催化、结构的分子是主要的班。除了 NPC 房间的已知的房间表面标记,分析在癌症房间是特征的疾病小径揭示了涉及多重发信号房间的小径的 311 蛋白质和 25 蛋白质。由寻找,差别表示了蛋白质数据库(http://protchem.hunnu.edu.cn/depd/index.jsp ) , 199 蛋白质被发现是在以前的癌症 proteome 研究表示的差别。671 蛋白质蛋白质相互作用网络被获得,包括在这个工作的 178 识别蛋白质。五蛋白质的血浆膜本地化被免疫学的技术证实,验证这 proteomic 策略。我们的学习能为理解 NPC 的分子的机制提供一些帮助。 | Lijun Zhang Xiaofang Jia Xiaohui Liu Tingting Sheng Rui Cao Quanyuan He Zhen Liu Xia Peng JixianXiong Pengfei Zhang Ni Shi Songping Liang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，1： | 5 |
| 5 | Deformation mechanism of fine grained Mg-7Gd-5Y-l.2Nd-0.5Zr alloy under high temperature and high strain rates显示文摘Fine grained Mg-7Gd-5Y-1.2Nd-0.5Zr alloy was investigated by dynamic compression tests using a Split Hopkinson Pressure Bar under the strain rates in the range 1000-2000 s^(-1) and the temperature range 293-573 K along the normal direction.The microstructure was measured by optical microscopy,electron back-scattering diffraction,transmission electron microscopy and X-ray diffractometry.The results showed that Mg-7Gd-5Y-1.2Nd-0.5Zr alloy had the positive strain rate strengthening effect and thermal softening effect at high temperature.The solid solution of Gd and Y atoms in Mg-7Gd-5Y-1.2Nd-0.5Zr alloy reduced the asymmetry of α-Mg crystals and changed the critical shear stress of various deformation mechanisms.The main deformation mechanisms were prismatic slip and pyramidal(a)slip,{102}tension twinning,and dynamic recrystallization caused by local deformation such as particle-stimulated nucleation.c 2020 Published by Elsevier B.V.on behalf of Chongqing University. | Wanru Tang Zheng Liu Shimeng Liu Le Zhou Pingli Mao Hui Guo Xiaofang Sheng | 2020 | Journal of Magnesium and Alloys2020，8，4： | 2 |
| 6 | Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a destructive pest native to America and has recently become an invasive insect pest in China.Because of its rapid spread and great risks in China,understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management strategies.Here,we assembled a chromosome-level genome of a male FAW(SFynMstLFR)and compared re-sequencing results of the populations from America,Africa,and China.Strain identification of 163 individuals collected from America,Africa and China showed that both C and R strains were found in the American pop-ulations,while only C strain was found in the Chinese and African populations.Moreover,population geno-mics analysis showed that populations from Africa and China have close relationship with significantly genetic differentiation from American populations.Taken toge-ther,FAWs invaded into China were most likely origi-nated from Africa.Comparative genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW,of which 283 genes are specific to FAW.Treatments of Chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles,and several detoxification genes such as AOX,UGT and GST spe-cially responded to the pesticides.These findings will be useful in developing effective strategies for manage-ment of FAW in China and other invaded areas. | Furong Gui Tianming Lan Yue Zhao Wei Guo Yang Dong Dongming Fang Huan Liu Haimeng Li Hongli Wang Ruoshi Hao Xiaofang Cheng Yahong Li Pengcheng Yang Sunil Kumar Sahu Yaping Chen Le Cheng Shuqi He Ping Liu Guangyi Fan Haorong Lu Guohai Hu Wei Dong Bin Chen Yuan Jiang Yongwei Zhang Hanhong Xu Fei Lin Bernard Slippers Alisa Postma Matthew Jackson Birhan Addisie Abate Kassahun Tesfaye Aschalew Lemma Demie Meseret Destaw Bayeleygne Dawit Tesfaye Degefu Feng Chen Paul K.Kuria Zachary M.Kinyua Tong-Xian Liu Huanming Yang Fangneng Huang Xin Liu Jun Sheng Le Kang | 2022 | Protein & Cell2022，13，7： | 2 |
| 7 | Effects of molecular weight and concentration of chitosan on antifungal activity against Aspergillus niger显示文摘 | LI Xiaofang FENG Xiaoqiang YANG Sheng | 2008 | Iranian Polymer Journal2008，17，11： | 1 |
| 8 | The com- plete genome sequence of a novel T4-1ike bacteriophage, IME08显示文摘 | Jiang Huanhuan Jiang Xiaofang Wang Sheng ei al | 2011 | Arch Virol2011，156，8： | 1 |
| 9 | Effects of molecular weight and concentration of chitosan on antifungal activity against Aspergillus niger显示文摘 | LI Xiaofang FENG Xiaoqiang YANG Sheng | 2008 | Iranian Polymer Journal2008，17，11： | 1 |
| 10 | Chitosan kills Escherichia coli through damage to be of cell membrane mechanism显示文摘 | Li Xiaofang Feng Xiaoqiang Yang Sheng | | 0，，03： | 1 |
| 11 | Effects of molecular weight and concentration of chitosan on antifungal activity against aspergillus niger显示文摘 | LI Xiaofang FENG Xiaoqiang YANG Sheng | 2008 | Iranian Polymer Journal2008，17，11： | 1 |
| 12 | Chitosan kills Escherichia coli through damage to be of cell membrane mechanism显示文摘 | LI XIAOFANG FENG XIAOQIANG YANG SHENG | 2010 | Carbohydrate Polymers2010，79，3： | 1 |
| 13 | Theoretical study of deactivation and isomerization pathways of 1,2-dithiete in excited electronic states显示文摘The potential energy surface crossings for 1,2-dithiete have been investigated using the complete active space self-consistent field(CASSCF) method and simple group theory.Using the full Pauli-Breit spin-orbit coupling(SOC) operator(■) SO) which consists of the one-electron(■) SO1) and two-electron(■) SO2) terms,we estimate the strengths of the SOC(198.37 cm-1 when symmetry is imposed,and 211.35 cm-1 with no symmetry constraints),which plays an essential role in the spin transitions between different spin states.The calculations show that the photolysis of 1,3-dithiol-2-one leads to the formation of trans-dithioglyoxal(trans-MinS0) as a primary product which subsequently gives a secondary product identified as thiolthioketene.Our calculated results are in close agreement with the experimental observations. | LV LingLing YANG Sheng WANG XiaoFang YUAN Kun LIU XinWen WANG YongCheng | 2009 | Science China Chemistry2009，52，8： | 0 |
| 14 | 常规加IMRT推量放疗联合化疗治疗高分级胶质瘤的疗效和 预后因素(英文)显示文摘Objective:The aim of the study was to retrospectively evaluate the outcomes and important prognostic factors for patients with high-grade gliomas (HGG) treated with conventional radiotherapy (RT) followed by IMRT as a boost in com- bination with chemotherapy. Methods: From November 2004 to November 2006,112 consecutive patients with high-grade gliomas were treated with radiotherapy,which included initial conventional radiotherapy and an IMRT boost to a total dose of 57.5–62.5 Gy,with 27-29 fractions delivered over 37–45 days. All cases received 3-6 cycles of chemotherapy,63 cases received temozolomide,and another 49 cases received methyl-CCNU and teniposide. The acute and late treatment toxicities and the patterns of treatment failure were recorded. The overall survival (OS) rate and progression-free survival (PFS) rate were calculated,and the prognostic factors were analyzed. Results: Most of the acute radiation reactions were grade 1 or 2. No grade 4 acute reactions were noted. Three cases developed radiation necrosis. Grades I,II,and III myelosuppressions were observed in 5,32,and 12 cases of 49 patients treated with teniposide and methyl-CCNU,respectively. Grades I and Ⅱ myelosuppressions were observed in 15 and 3 of the 6 3 patients who were treated with temozolomide,respectively. The 57 cases (50.9%) had recurred locally,and 13 cases (11.6%) had intracranial dissemination. The OS rates at 1,2,and 3 years were 78.9%,54.7%,and 30.8%,respectively. The PFS rates at 1,2,and 3 years were 63.8%,38.9%,and 10.5%,respectively. A multivariate analysis showed that only tumor location and KPS were prognostic factors of OS. These same two variables and histopathology were statistically significant predictive factors in a multivariate analysis for PFS. Conclusion:Radiation toxicities were not found to be increased in this retrospective study with 112 consecutive patients of combined modality therapy including an IMRT boost treatment for HGG. Higher rate of local regional dissemination within the brain was observed than before. Tumor location,histopathology and KPS were important prognostic factors. | Yang Wang Xiaofang Sheng Li Pan Jin Gao Shu Chen Wei Dong Lei Sun Jiazhong Dai | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，6： | 0 |
| 15 | Investigating the Immunogenic Cell Death‑Dependent Subtypes and Prognostic Signature of Triple‑Negative Breast Cancer显示文摘Recently,immunotherapy has emerged as a promising and efective method for treating triple-negative breast cancer(TNBC).However,challenges still persist.Immunogenic cell death(ICD)is considered a prospective treatment and potential combinational treatment strategy as it induces an anti-tumor immune response by presenting the antigenic epitopes of dead cells.Nevertheless,the ICD process in TNBC and its impact on disease progression and the response to immunotherapy are not well understood.In this study,we observed dysregulation of the ICD process and verifed the altered expression of prognostic ICD genes in TNBC through quantitative real-time polymerase chain reaction(qRT-PCR)analysis.To investigate the potential role of the ICD process in TNBC progression,we determined the ICD-dependent subtypes,and two were identifed.Analysis of their distinct tumor immune microenvironment(TIME)and cancer hallmark features revealed that Cluster 1 and 2 corresponded to the immune“cold”and“hot”phenotypes,respectively.In addition,we constructed the prognostic signature ICD score of TNBC patients and demonstrated its clinical independence and generalizability.The ICD score could also serve as a potential biomarker for immune checkpoint blockade and may aid in the identifcation of targeted efective agents for individualized clinical strategies. | Youyang Shi Yuanyuan Wu Feifei Li Kexin Jiang Xiaofang Fang Yu Wang Xiaoyun Song Rui Wang Lixin Chen Jinzhou Zheng Chunyu Wu Yuenong Qin Xiaofei Liu Sheng Liu | 2024 | Phenomics2024，4，1： | 0 |
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