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| 1 | Tree-ring based PDSI reconstruction since AD 1842 in the Ortindag Sand Land,east Inner Mongolia显示文摘epartment of Wood Science, University of Hamburg, Hamburg D-21031, GermanyBased on three Chinese pine (Pinus tabulaeformis Carr.) and one Meyer spruce (Picea meyeri Rehd. et Wils.) ring-width chronologies, a 163-year drought history was reconstructed in the eastern Ortindag Sand Land. All tree-ring chronologies show large inter-annual variations and strong common signals and fairly consistent variation between different chronologies, indicating that they are excellent proxy of regional climate. A regional chronology (RC) was established by averaging the four standard chronologies and further employed for the analysis and climatic reconstruction. The analysis revealed that tree growth is primarily limited by low precipitation in February-March and June-July and high temperature in May-July. In addition, RC has high correlations with the monthly Palmer drought severity index (PDSI) prior to and during the growing season because the PDSI considers the accumulation of the droughts. Response function analysis revealed that RC only exhibits significant correlations with the PDSI in June and July (close to the 95% significance level in May). Because May―July is a critical period for tree growth, the average May-July PDSI (PDSI5-7) was reconstructed back to 1842 using RC in the Ortindag Sand Land. The reconstruction can explain 52% of the PDSI variance and the equation was rather stable over time. It agrees well with the variation of the average dryness/wetness indices in North China,and captures the decline process of the East Asian summer monsoon since the mid-1960s. It is worth noting that the Ortindag Sand Land has experienced the most severe drought in the recent 40 years based on the 163-year drought reconstruction. Like summer precipitation in North China the reconstructed PDSI5-7 also displays a 20-year oscillation. | LIANG ErYuan SHAO XueMei LIU HongYan ECKSTEIN Dieter | 2007 | Chinese Science Bulletin2007，52，19： | 37 |
| 2 | Millennial temperature reconstruction based on tree-ring widths of Qilian juniper from Wulan,Qinghai Province,China显示文摘The climate of the past 1000 years is an important context for evaluating the recent climate warming.However,there are few 1000-year-long climate reconstructions with annual resolution in the Qing-hai-Tibet Plateau.In this paper,a dendroclimatic analysis was conducted for the radial growth of Qilian juniper from the upper forest limit in Wulan,Qinghai Province.The results of correlation analysis between the tree-ring widths and the climate variables indicate that the growth of junipers at the upper forest limit is mainly limited by low temperatures of September,November and February of the pregrowth season,and July of the current growth season.There is no significant correlation between the tree-ring widths and precipitation.A mean temperature from the previous year's September to the current year's April was reconstructed for the Wulan area since A.D.1000.The reconstruction can explain 40.8% of the instrumental variance in the calibration period(1856―2002).The reconstruction shows that the 20th century is the warmest 100 years,and the 1990s is the warmest decade during the past 1000 years,while the coldest 100 years and decade occur at 1600―1699 and 1642―1651,respectively.The variations are verified well by the temperature reconstruction of the middle Qilian Mountain(QL) and the total organic carbon(TOC) in the Qinghai Lake sediments.The comparison of our reconstruction with the annual temperature reconstruction of extra-tropical Northern Hemisphere suggests that the climate of Wulan during the Medieval Warm Period is of obvious regional specialty,but there was a good response to the climate of hemispheric scales during the recent 400 years. | ZHU HaiFeng ZHENG YongHong SHAO XueMei LIU XiaoHong XU Yan LIANG ErYuan | 2008 | Chinese Science Bulletin2008，53，24： | 40 |
| 3 | WRF/CHEM modeling of impacts of weather conditions modified by urban expansion on secondary organic aerosol formation over Pearl River Delta显示文摘In this paper,the online Weather Research and Forecasting and Chemistry (WRF/CHEM) model,coupled with urban canopy (UCM) and biogenic-emission models,is used to explore impacts of urban expansion on secondary organic aerosols (SOA) formation. Two scenarios of urban maps are used in WRF/CHEM to represent early 1990s (pre-urbanization) and current urban distribution in the Pearl River Delta (PRD). Month-long simulation results using the above land-use scenarios for March 2001 show:(1) urbanization can increase monthly averaged temperatures by about 0.63 ?C,decrease monthly averaged 10-m wind speeds by 38%,increase monthly averaged boundary-layer depths by 80 m,and decrease monthly aver-aged water mixing ratio by 0.2 g/kg. (2) Changes in meteorological conditions can result in detectable concentration changes of NOx,VOC,O3 and NO3 radicals. Urbanization decreases surface NOx and VOC concentrations by a maximum of 4 ppbv and 1.5 ppbv,respectively. Surface O3 and NO3 radical concen-trations over major cities increase by about 2-4 ppbv and 4-12 pptv,respectively; areas with increasing O3 and NO3 radical concentrations generally coincide with the areas of temperature increase and wind speed reduction where NOx and VOC decrease. (3) Urbanization can induce 9% increase of SOA in Foshan,Zhongshan and west Guangzhou and 3% decrease in Shenzhen and Dongguan. Over PRD major cities,SOA from Aitken mode reduces by 30% but with more than 70% SOA from accumulate mode. Urbanization has stronger influence on SOA formation from Aitken mode. (4) Over the PRD,55-65% SOA comes from aromatics precursors. Urbanization has strongest influence on aromatics precursors to produce SOA (14% increase),while there is less influence on alkane precursors. Alkene precursors have negative contribution to SOA formation under urbanization situation. | Xuemei Wang Zhiyong Wu Guixiong Liang | 2009 | Particuology2009，7，5： | 25 |
| 4 | CO_2 capture from binary mixture via forming hydrate with the help of tetra-n-butyl ammonium bromide显示文摘Hydrate formation rate and separation effect on the capture of CO2 from binary mixture via forming hydrate with 5 wt% tetra-n-butyl ammonium bromide (TBAB) solution were studied. The results showed that the induction time was 5 min, and the hydrate formation process finished in 1 h at 4.5 °C and 4.01 MPa. The hydrate formation rate constant reached the maximum of 1.84×10-7 mol2/(s J) with the feed pressure of 7.30 MPa. The CO2 recovery was about 45% in the feed pressure range from 4.30 to 7.30 MPa. Under the feed pressure of 4.30 MPa, the maximum separation factor and CO2 concentration in hydrate phase were 7.3 and 38.2 mol%, respectively. The results demonstrated that TBAB accelerated hydrate formation and enriched CO2 in hydrate phase under the gentle condition. | Shifeng Li Shuanshi Fan Jingqu Wang Xuemei Lang Deqing Liang | 2009 | Journal of Natural Gas Chemistry2009，18，1： | 22 |
| 5 | Effects of dietary supplementation with essential oils and protease on growth performance,antioxidation,inflammation and intestinal function of weaned pigs显示文摘This experiment evaluated the impacts of essential oils(EO)and protease(PRO),independently or in combination,on growth performance,antioxidation,inflammation and intestinal function of weaned pigs.One hundred and sixty weaned pigs(21 d of age,BW of 6.74±0.20 kg)were randomly divided into 4 treatments with 8 replicate pens of 5 pigs per pen.Dietary treatments included the following:1)control diet(CON),2)CON with 300 mg/kg essential oils(EO),3)CON with 500 mg/kg protease(PRO),4)CON with 300 mg/kg essential oil and 500 mg/kg protease(EO + PRO).On d 8,one pig from each penwas selected for sampling.The remaining pigs were fed for an additional week and growth performance was monitored during this period.Dietary treatments had no marked effects(P>0.05)on the growth performance of pigs.However,pigs receiving EO diet had higher(P<0.05)serumglutathione peroxidase(GSH-Px)activity,and tended to decrease(P=0.063)serum concentration of tumor necrosis factor-a(TNF-a).In addition,pigs receiving EO diet had higher(P<0.05)abundances of phylum Actinobacteria,and genera Bifidobacterium,and lower(P<0.05)phylum Bacteroidetes and genera Alloprevotella in colonic digesta.Pigs receiving PRO diet decreased(P<0.05)the serum concentration of malondialdehyde(MDA)and diamine oxidase activity,increased(P<0.05)the villus height and the ratio of villus height to crypt depth in duodenum,increased sucrase activity in jejunal mucosa,and also increased the abundance of phylum Actinobacteria in colonic digesta.Furthermore,the synergistic effects of EO and PROwas observed(P<0.05)for pigs with decreasing serum TNF-a concentration and increasing serum GSH-Px activity.Collectively,the results indicated that dietary supplementation of EO and PRO had no significant effects on growth performance of weaned pigs.EO diet appeared to improve antioxidant activity and intestinal microbiota,while PRO diet improved intestinal morphology and digestive enzyme activity,and there was a synergistic effect of EO and PRO on reducing inflammatory parameters in weaned pigs. | Xie Peng Qiang Zhou Cheng Wu Jian Zhao Quan Tan Ying He Liang Hu Zhengfeng Fang Yan Lin Shengyu Xu Bin Feng Jian Li Yong Zhuo Chris Van Ginneken Xuemei Jiang De Wu Lianqiang Che | 2022 | Animal Nutrition2022，，2： | 8 |
| 6 | Comparative genomic and transcriptomic analyses uncover the molecular basis of high nitrogen-use efficiency in the wheat cultivar Kenong 9204显示文摘Studying the regulatory mechanisms that drive nitrogen-use efficiency(NUE)in crops is important for sustainable agriculture and environmental protection.In this study,we generated a high-quality genome assembly for the high-NUE wheat cultivar Kenong 9204 and systematically analyzed genes related to nitrogen uptake and metabolism.By comparative analyses,we found that the high-affinity nitrate transporter gene family had expanded in Triticeae.Further studies showed that subsequent functional differentiation endowed the expanded family members with saline inducibility,providing a genetic basis for improving the adaptability of wheat to nitrogen deficiency in various habitats.To explore the genetic and molecular mechanisms of high NUE,we compared genomic and transcriptomic data from the high-NUE cultivar Kenong 9204(KN9204)and the low-NUE cultivar Jing 411 and quantified their nitrogen accumulation under high-and low-nitrogen conditions.Compared with Jing 411,KN9204 absorbed significantly more nitrogen at the reproductive stage after shooting and accumulated it in the shoots and seeds.Transcriptome data analysis revealed that nitrogen deficiency clearly suppressed the expression of genes related to cell division in the young spike of Jing 411,whereas this suppression of gene expression was much lower in KN9204.In addition,KN9204 maintained relatively high expression of NPF genes for a longer time than Jing 411 during seed maturity.Physiological and transcriptome data revealed that KN9204 was more tolerant of nitrogen deficiency than Jing 411,especially at the reproductive stage.The high NUE of KN9204 is an integrated effect controlled at different levels.Taken together,our data provide new insights into the molecular mechanisms of NUE and important gene resources for improving wheat cultivars with a higher NUE trait. | Xiaoli Shi Fa Cui Xinyin Han Yilin He Long Zhao Na Zhang Hao Zhang Haidong Zhu Zhexin Liu Bin Ma Shusong Zheng Wei Zhang Jiajia Liu Xiaoli Fan Yaoqi Si Shuiquan Tian Jianqing Niu Huilan Wu Xuemei Liu Zhuo Chen Deyuan Meng Xiaoyan Wang Liqiang Song Lijing Sun Jie Han Hui Zhao Jun Ji Zhiguo Wang Xiaoyu He Ruilin Li Xuebin Chi Chengzhi Liang Beifang Niu Jun Xiao Junming Li Hong-Qing Ling | 2022 | Molecular Plant2022，15，9： | 6 |
| 7 | Association of chronic obstructive pulmonary disease with type 2 diabetes mellitus显示文摘Chronic obstructive pulmonary disease (COPD) is a complex disorder,characterized by an irreversible airflow limitation during breathing.This may lead to various extrapulmoanry comorbidities,such as cardiovascular disease,osteoporosis,and diabetes mellitus (DM).1 Type 2 (T2DM) accounts for a large proportion of DM,and is also showing a rising prevalence in developed and developing countries.2 In addition to the known factors for T2DM,several studies have demonstrated that COPD is also an important risk factor for T2DM.In this study,we aimed to determine the prevalence of COPD in patients with T2DM,and to analyze the clinical characteristics of COPD accompanied by T2DM. | Wang Maoyun Yang Jing Ke Hua Wang Bo Liang Binmiao Ou Xuemei Feng Yulin | 2014 | Chinese Medical Journal2014，，17： | 5 |
| 8 | The correlation between nitrogen species in coke and NO_x formation during regeneration显示文摘Nitrogen oxides(NO x)emission during the regeneration of coked fluid catalytic cracking(FCC)catalysts is an environmental issue.In order to identify the correlations between nitrogen species in coke and different nitrogencontaining products in tail gas,three coked catalysts with multilayer structural coke molecules were prepared in a fixed bed with model compounds(o-xylene and quinoline)at first.A series of characterization methods were used to analyze coke,including elemental analysis,FT-IR,XPS,and TG–MS.XPS characterization indicates all coked catalysts present two types of nitrogen species and the type with a higher binding energy is related with the inner part nitrogen atoms interacting with acid sites.Due to the stronger adsorption ability on acid sites for basic nitrogen compounds,the multilayer structural coke has unbalanced distribution of carbon and nitrogen atoms between the inner part and the outer edge,which strongly affects gas product formation.At the early stage of regeneration,oxidation starts from the outer edge and the product NO can be reduced to N_2 in high CO concentration.At the later stage,the inner part rich in nitrogen begins to be exposed to O_2.At this period,the formation of CO decreases due to lack of carbon atoms,which is not bene ficial to the reduction of NO.Therefore,nitrogen species in the inner part of multilayer structural coke contributes more to NO X formation.Based on the multilayer structure model of coke molecule and its oxidation behavior,a possible strategy to control NO X emission was discussed merely from concept. | Teng Li Chaohe Yang Xiaobo Chen Libo Yao Wei Liang Xuemei Ding | 2016 | Chinese Journal of Chemical Engineering2016，24，5： | 5 |
| 9 | Fast-Suppressor Screening for New Components in Protein Trafficking,Organelle Biogenesis and Silencing Pathway in Arabidopsis thaliana Using DEX-Inducible FREE1-RNAi Plants显示文摘Membrane trafficking is essential for plant growth and responses to external signals.The plant unique FYVE domain-containing protein FREE1 is a component of the ESCRT complex(endosomal sorting complex required for transport).FREE1 plays multiple roles in regulating protein trafficking and organelle biogenesis including the formation of intraluminal vesicles of multivesicular body(MVB),vacuolar protein transport and vacuole biogenesis,and autophagic degradation.FREE1 knockout plants show defective MVB formation,abnormal vacuolar transport,fragmented vacuoles,accumulated autophagosomes,and seedling lethality.To further uncover the underlying mechanisms of FREE1 function in plants,we performed a forward genetic screen for mutants that suppressed the seedling lethal phenotype of FREE1-RNAi transgenic plants.The obtained mutants are termed as suppressors of free1(sof).To date,229 putative sof mutants have been identified.Barely detecting of FREE1 protein with M3plants further identified 84 FREE1-related suppressors.Also145 mutants showing no reduction of FREE1 protein were termed as RNAi-related mutants.Through next-generation sequencing(NGS)of bulked DNA from F2mapping population of two RNAi-related sof mutants,FREE1-RNAi T-DNA inserted on chromosome 1 was identified and the causal mutation of putative sof mutant is being identified similarly.These FREE1-and RNAi-related sof mutants will be useful tools and resources for illustrating the underlying mechanisms of FREE1 function in intracellular trafficking and organelle biogenesis,as well as for uncovering the new components involved in the regulation of silencing pathways in plants. | Qiong Zhao Caiji Gao PoShing Lee Lin Liu Shaofang Li Tangjin Hu Jinbo Shen Shuying Pan Hao Ye Yunru Chen Wenhan Cao Yong Cui Peng Zeng Sheng Yu Yangbin Gao Liang Chen Beixin Mo Xin Liu Shi Xiao Yunde Zhao Silin Zhong Xuemei Chen Liwen Jiang | 2015 | Journal of Genetics and Genomics2015，42，6： | 4 |
| 10 | A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy显示文摘The combination of Ce6,an acknowledged photosensitizer,and TPL,a natural anticancer agent,has been demonstrated as a useful strategy to reinforce the tumor growth suppression,as well as decrease the systemic side effects compared with their monotherapy.However,in view of the optimal chemo-photodynamic combination efficiency,there is still short of the feasible nanovehicle to steadily co-deliver Ce6 and TPL,and stimuli-responsively burst release drugs in tumor site.Herein,we described the synergistic antitumor performance of a pH-sensitive supramolecular nanosystem,mediated by the host–guest complexing betweenβ-CD and acid pH-responsive amphiphilic co-polymer mPEG-PBAE-mPEG,showing the shell–core structural micelles with the tightβ-CD layer coating.Both Ce6 and TPLwere facilely co-loaded into the spherical supramolecular NPs(TPL+Ce6/NPs)by one-step nanoprecipitation method,with an ideal particle size(156.0 nm),acid pH-responsive drug release profile,and enhanced cellular internalization capacity.In view of the combination benefit of photodynamic therapy and chemotherapy,as well as co-encapsulation in the fabricated pH-sensitive supramolecular NPs,TPL+Ce6/NPs exhibited significant efficacy to suppress cellular proliferation,boost ROS level,lower MMP,and promote cellular apoptosis in vitro.Particularly,fluorescence imaging revealed that TPL+Ce6/NPs preferentially accumulated in the tumor tissue area,with higher intensity than that of free Ce6.As expected,upon 650-nm laser irradiation,TPL+Ce6/NPs exhibited a cascade of amplified synergistic chemo-photodynamic therapeutic benefits to suppress tumor progression in both hepatoma H22 tumor-bearingmice and B16 tumor-bearingmice.More importantly,lower systemic toxicitywas found in the tumor-bearingmice treated with TPL+Ce6/NPs.Overall,the designed supramolecular TPL+Ce6/NPs provided a promising alternative approach for chemo-photodynamic therapy in tumor treatment. | Yihan Wu Jingjing Li Xuemei Zhong Jinfeng Shi Yanfen Cheng Chenglin He Jiaxin Li Liang Zou Chaomei Fu Meiwan Chen Jinming Zhang Huile Gao | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，2： | 4 |
| 11 | Life History Recorded in the Vagino-cervical Microbiome Along with Multi-omes显示文摘The vagina contains at least a billion microbial cells,dominated by lactobacilli.Here we perform metagenomic shotgun sequencing on cervical and fecal samples from a cohort of 516 Chinese women of reproductive age,as well as cervical,fecal,and salivary samples from a second cohort of 632 women.Factors such as pregnancy history,delivery history,cesarean section,and breastfeeding were all more important than menstrual cycle in shaping the microbiome,and such information would be necessary before trying to interpret differences between vagino-cervical microbiome data.Greater proportion of Bifidobacterium breve was seen with older age at sexual debut.The relative abundance of lactobacilli especially Lactobacillus crispatus was negatively associated with pregnancy history.Potential markers for lack of menstrual regularity,heavy flow,dysmenorrhea,and contraceptives were also identified.Lactobacilli were rare during breastfeeding or post-menopause.Other features such as mood fluctuations and facial speckles could potentially be predicted from the vagino-cervical microbiome.Gut and salivary microbiomes,plasma vitamins,metals,amino acids,and hormones showed associations with the vagino-cervical microbiome.Our results offer an unprecedented glimpse into the microbiota of the female reproductive tract and call for international collaborations to better understand its long-term health impact other than in the settings of infection or pre-term birth. | Zhuye Jie Chen Chen Lilan Hao Fei Li Liju Song Xiaowei Zhang Jie Zhu Liu Tian Xin Tong Kaiye Cai Zhe Zhang Yanmei Ju Xinlei Yu Ying Li Hongcheng Zhou Haorong Lu Xuemei Qiu Qiang Li Yunli Liao Dongsheng Zhou Heng Lian Yong Zuo Xiaomin Chen Weiqiao Rao Yan Ren Yuan Wang Jin Zi Rong Wang Na Liu Jinghua Wu Wei Zhang Xiao Liu Yang Zong Weibin Liu Liang Xiao Yong Hou Xun Xu Huanming Yang Jian Wang Karsten Kristiansen Huijue Jia | 2022 | Genomics, Proteomics & Bioinformatics2022，20，2： | 2 |
| 12 | Tuning crystal structure and redox potential of NASICON-type cathodes for sodium-ion batteries显示文摘Sodium superionic conductor(NASICON)-type compounds have been regarded as promising cathodes for sodium-ion batteries(SIBs)due to their favorable ionic conductivity and robust structural stability.However,their high cost and relatively low energy density restrict their further practical application,which can be tailored by widening the operating voltages with earth-abundant elements such as Mn.Here,we propose a rational strategy of infusing Mn element in NASICON frameworks with sufficiently mobile sodium ions that enhances the redox voltage and ionic migration activity.The optimized structure of Na3.5Mn0.5V1.5(PO4)3/C is achieved and investigated systematically to be a durable cathode(76.6%capacity retention over 5,000 cycles at 20 C)for SIBs,which exhibits high reversible capacity(113.1 mAh·g^−1 at 0.5 C)with relatively low volume change(7.6%).Importantly,its high-areal-loading and temperature-resistant sodium ion storage properties are evaluated,and the full-cell configuration is demonstrated.This work indicates that this Na3.5Mn0.5V1.5(PO4)3/C composite could be a promising cathode candidate for SIBs. | Xuemei Ma Xinxin Cao Yifan Zhou Shan Guo Xiaodong Shi Guozhao Fang Anqiang Pan Bingan Lu Jiang Zhou Shuquan Liang | 2020 | Nano Research2020，13，12： | 2 |
| 13 | Hyperactive PI3Kδ predisposes naive T cells to activation via aerobic glycolysis programs显示文摘Activated phosphoinositide 3-kinaseδsyndrome(APDS)is an autosomal-dominant combined immunodeficiency disorder resulting from pathogenic gain-of-function(GOF)mutations in the PIK3CD gene.Patients with APDS display abnormal T cell homeostasis.However,the mechanisms by which PIK3CD GOF contributes to this feature remain unknown.Here,with a cohort of children with PIK3CD GOF mutations from multiple regions of China and a corresponding CRISPR/Cas9 gene-edited mouse model,we reported that hyperactive PI3Kδdisrupted TNaive cell homeostasis in the periphery by intrinsically promoting the growth,proliferation,and activation of TNaive cells.Our results showed that PIK3CD GOF resulted in loss of the quiescence-associated gene expression profile in naive T cells and promoted naive T cells to overgrow,hyperproliferate and acquire an activated functional status.Naive PIK3CD GOF T cells exhibited an enhanced glycolytic capacity and reduced mitochondrial respiration in the resting or activated state.Blocking glycolysis abrogated the abnormal splenic T cell pool and reversed the overactivated phenotype induced by PIK3CD GOF in vivo and in vitro.These results suggest that enhanced aerobic glycolysis is required for PIK3CD GOF-induced overactivation of naive T cells and provide a potential therapeutic approach for targeting glycolysis to treat patients with APDS as well as other immune disorders. | Yanjun Jia Qiuyun Yang Yanping Wang Wenyan Li Xuemei Chen Tao Xu Zhirui Tian Minxuan Feng Liang Zhang Wenjing Tang Na Tian Lina Zhou Wenxia Song Xiaodong Zhao | 2021 | Cellular & Molecular Immunology2021，18，7： | 2 |
| 14 | Advances in Urban Meteorological Research in China显示文摘Over the past decades,a large number of studies have been carried out in the field of urban meteorology in China.This paper summarizes the main progress in urban meteorology research from four aspects:urban meteorological observation network and field campaign,multi-scale model of urban meteorology,interaction between urban meteorology and atmospheric environment,and the impacts of urbanization on weather and climate.Major advances are as follows.China’s major cities have established or are improving comprehensive urban meteorological observation networks characterized by multi-platform,multi-variable,multi-scale,multi-link,and multi-function.Beijing,Nanjing,Shanghai,and other cities carried out urban meteorological field campaigns,which were included in the WMO research demonstration project.Wind tunnel experiments and scale-model outdoor experiments were successfully conducted.Multi-scale urban meteorological and air quality prediction numerical model systems have been developed and put into operational use.The urban heat island effect;urban impacts on precipitation,regional climate,and air quality;urban planning;and interaction between urban meteorology and atmospheric environment are extensively investigated.Finally,efforts to improve observational technology,data assimilation,and urban system modeling,to explore the impacts of urbanization on environment and human health,and to provide integrated urban hydro-meteorological climate and environmental services are planned ahead. | Shiguang MIAO Weimei JIANG Ping LIANG Hongnian LIU Xuemei WANG Jianguo TAN Ning ZHANG Ju LI Wupeng DU Lin PEI | 2020 | Journal of Meteorological Research2020，34，2： | 2 |
| 15 | Mediating effect of interpersonal relations on negative emotions and dysmenorrhea in female adolescents显示文摘Background Good interpersonal relationships can improve the negative mood and, to a certain extent, may help relieve dysmenorrhea symptoms. However, there has been no study examining the role of interpersonal relationships in dysmenorrhea and how they may interact with negative emotions. Aims To investigate the connection between negative affect and dysmenorrhea, and the role of interpersonal relationships plays in this relationship. Methods The Cox Menstrual Symptom Scale (CMSS), short-form of Depression Anxiety Stress Scale, Interpersonal Comprehensive Diagnostic Scale and UCLA (University of California at Los Angeles) Loneliness Scale were applied to 855 adolescent nursing students to collect information on severity and frequency of dysmenorrheal symptoms, negative emotions (including depression, anxiety and stress), interpersonal problems and subjective experience of loneliness among them, and the relationship among these variables was examined. Results (1) Both the severity and frequency of dysmenorrhea were positively correlated with negative emotions, loneliness experience and interpersonal problems, while negatively correlated with age at menarche.(2) The negative emotions, romantic relationship and menarche age, but not loneliness and interpersonal problems, significantly contributed to both the severity and frequency of dysmenorrhea.(3) Mediation analysis revealed that the effects of loneliness and interpersonal problems on dysmenorrhea were totally mediated by negative emotions. Conclusions This investigation indicates that the relationship between interpersonal relationships and dysmenorrhea is mediated by negative emotions. | Lingli Mou Wei Lei Jing Chen Rong Zhang Kezhi Liu Xuemei Liang | 2019 | General Psychiatry2019，32，1： | 2 |
| 16 | The 1920S Drought Recorded by Tree Rings and Historical Documents in the Semi-Arid and Arid Areas of Northern China显示文摘 | Eryuan Liang Xiaohong Liu Yujiang Yuan Ningsheng Qin Xiuqi Fang Lei Huang Haifeng Zhu Lily Wang Xuemei Shao | 2006 | Climatic Change (-)2006，，3： | 1 |
| 17 | Dendroclimatic evaluation of climate-growth relationships of Meyer spruce (Picea meyeri) on a sandy substrate in semi-arid grassland, north China显示文摘 | Eryuan Liang Xuemei Shao Yuxi Hu Jinxing Lin | 2001 | Trees2001，，4： | 1 |
| 18 | Growth variation in Abies georgei var. smithii along altitudinal gradients in the Sygera Mountains, southeastern Tibetan Plateau显示文摘 | Eryuan Liang Yafeng Wang Yan Xu Bo Liu Xuemei Shao | 2010 | Trees2010，，2： | 1 |
| 19 | The 1920S Drought Recorded by Tree Rings and Historical Documents in the Semi-Arid and Arid Areas of Northern China显示文摘 | Eryuan Liang Xiaohong Liu Yujiang Yuan Ningsheng Qin Xiuqi Fang Lei Huang Haifeng Zhu Lily Wang Xuemei Shao | 2006 | Climatic Change (-)2006，，3： | 1 |
| 20 | Progress and development directions of shale oil reservoir stimulation technology of China National Petroleum Corporation显示文摘By reviewing the development history of shale oil reservoir stimulation technology of PetroChina Company Limited(PetroChina),we have systematically summarized the main progress of shale oil reservoir stimulation technology of CNPC in five aspects:reservoir stimulation mechanism,fracture-controlled fracturing,geological-engineering integrated reservoir stimulation design platform,low-cost materials,and large well-pad three-dimensional development mode.It is made clear that the major stimulation technology for shale oil reservoir is the high density multi-cluster and fracture-controlled staged fracturing aiming to increase fracture-controlled reserves,lower operation costs and increase economic benefits.Based on comprehensive analysis of the challenges shale oil reservoir stimulation technology faces in three-dimensional development,stimulation parameter optimization for fracture-controlled fracturing,refracturing and low-cost stimulation technology,we proposed five development directions of the stimulation technology:(1)Strengthen the research on integration of geology and engineering to make full use of reservoir stimulation.(2)Deepen the study on fracture-controlled fracturing to improve reserves development degree.(3)Promote horizontal well three-dimensional development of shale oil to realize the production of multiple layers vertically.(4)Research refracturing technology of shale oil reservoir through horizontal well to efficiently tap the remaining reserves between fractures.(5)Develop low-cost stimulation supporting technology to help reduce the cost and increase economic benefit of oilfield development. | LEI Qun WENG Dingwei XIONG Shengchun LIU Hanbin GUAN Baoshan DENG Qjang YAN Xuemei LIANG Hongbo MA Zeyuan | 2021 | Petroleum Exploration and Development2021，48，5： | 1 |
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