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| 1 | Temporal variation of soil carbon stock and its controlling factors over the last two decades on the southern Song-nen Plain,Heilongjiang Province显示文摘对全球气候变化的当前的背景,在土壤碳水池和它的控制因素的变化的学习可以在温室气体的缓解或改进帮助土壤角色的评估。这份报纸在 Heilongjiang 省在南部的 Song-nen 平原在土壤碳水池和他们的控制因素学习空间、时间的变化,用在二个不同时期由上收集的土壤数据在 20052007 的多种用途的地区性的 Geochemical 调查,和另外一个玷污在 19821990 进行的调查。学习区域是 1479 t/km2 并且在过去的 20 年里的碳来源,从直到 2005 的 1980 年代,从土壤的实际的碳排放是 0.12 Gt。温度,被发现了线性地被相关玷污器官的碳,是控制器官的碳满足的土壤的主导的 climatologic 因素。我们的学习在器官的碳由升起的温度引起了的土壤的潜在的损失是的相关区域和时间时期显示出那 0.10 Gt ,源于陆地使用变化的潜在的土壤碳排放是 0.09 Gt ,并且温暖和陆地使用变化引起的土壤碳( 0.19 Gt )的联合潜在的损失比得上石块燃料燃烧( 0.21 Gt )的。由于在土壤碳水池变化的时间延期,仍然在温暖和以后将逐渐地被释放的陆地使用变化引起的潜在的排放有 0.07 Gt。 | Xueqi Xia Zhongfang Yang Yan Liao Yujun Cui Yansheng Li | 2010 | Geoscience Frontiers2010，1，1： | 19 |
| 2 | Study of TiC+TiN Multiple Films On Type of 316L Stainless Steel显示文摘In this paper, the synthesis process of TiC+TiN multiple films on super-low-carbon stainless steels is reported. The TiC layer is coated as the first layer in the multiple film, the change of growth rate of the film on the 316L Stainless steel is not same as the one on carbides substrates, while the mole ratio of CRi to TiCLi (mCH/TiCl4) is changed from 1.2 to 2.0. The Ti [C, N], as a kind of inter-layer between TiC and TiN layers, is helpful to improve the adhesion between the TiC and TiN layer. The cooling rate greatly influences the quality of the adhesion between the TiC+TiN film and substrates. | XUEQi JINYong HUDong-ping HUANGBen-sheng DENGBai-quan | 2004 | 材料热处理学报2004，25，05B： | 10 |
| 3 | Investigation of Mg–Zn–Y–Nd alloy for potential application of biodegradable esophageal stent material显示文摘In recent years,due to unhealthy dietary habits and other reasons,advanced esophageal cancer patients are on the rise,threatening human health and life safety at all times.Stents implantation as an important complementary or alternative method for chemotherapy has been widely applied in clinics.However,the adhesion and proliferation of pathological cells,such as tumor cells,fibroblasts and epithelial cells,may interfere the efficacy of stents.Further multiple implantation due to restenosis may also bring pain to patients.In this contribution,we preferred a biodegradable material Mg–Zn–Y–Nd alloy for potential application of esophageal stent.The hardness testing showed that Mg–Zn–Y–Nd alloy owned less mechanical properties compared with the commercial esophageal stents material,317L stainless steel(317L SS),while Mg–Zn–Y–Nd displayed significantly better biodegradation than 317L SS.Cell apoptosis assay indicated Mg–Zn–Y–Nd inhibited adhesion and proliferation of tumor cells,fibroblasts and epithelial cells.Our research suggested potential application of Mg–Zn–Y–Nd alloy as a novel material for biodegradable esophageal stent. | Shuo Wang Xueqi Zhang Jingan Li Changsheng Liu Shaokang Guan | 2020 | Bioactive Materials2020，5，1： | 7 |
| 4 | Potential risks and challenges of climate change in the arid region of northwestern China显示文摘In the arid region of northwestern China(ARNC),water resources are the most critical factor restricting socioeconomic development and influencing the stability of the area’s ecological systems.The region’s complex water system and unique hydrological cycle show distinctive characteristics.Moreover,the intensified hydrological cycle and extreme climatic and hydrological events resulting from global warming have led to increased uncertainty around water resources as well as heightened conflict between water supply and water demand.All of these factors are exerting growing pressures on the socioeconomic development and vulnerable ecological environment in the region.This research evaluates the impacts of climate change on water resources,hydrological processes,agricultural system,and desert ecosystems in the ARNC,and addresses some associated risks and challenges specific to this area.The temperature is rising at a rate of 0.31C per decade during 1961–2017 and hydrological processes are being significantly influenced by changes in glaciers,snow cover,and precipitation form,especially in the rivers recharged primarily by melt water.Ecosystems are also largely influenced by climate change,with the Normalized Difference Vegetation Index(NDVI)of natural vegetation exhibited an increasing trend prior to 1998,and then reversed in Xinjiang while the Hexi Corridor of Gansu showed the opposite trends.Furthermore,the desert-oasis transition zone showed a reduction in area due to the warming trend and the recent rapid expansion of irrigated area.Both the warming and intensified drought are threatening agriculture security.The present study could shed light on sustainable development in this region under climate change and provides scientific basis to the construction of the“Silk Road Economic Belt”. | Yaning Chen Xueqi Zhang Gonghuan Fang Zhi Li Fei Wang Jingxiu Qin Fan Sun | 2020 | Regional Sustainability2020，1，1： | 6 |
| 5 | Safety and Efficacy of Physical Thermal Ablation Combined Sorafenib for Hepatocellular Carcinoma:A Meta-analysis显示文摘Background and Aims:To compare the efficacy and safety of physical thermal ablation(PTA),including radiofrequency ablation(RFA)and microwave ablation(MWA),combined with sorafenib and physical thermal ablation alone for the control and treatment of hepatocellular carcinoma(HCC)according to the available literature.Methods:Comprehensive searches were performed on PubMed,Embase,CNKI,the Cochrane Library,China Biomedical Literature Database(known as CBM),Weipu Journal,and Wanfang Database.Meta-analysis was performed using Revman 5.3 software.Results:A total of 15 studies,consisting of 2,227 HCC patients,were selected and included in this meta-analysis.Compared with the RFA-alone group,the patients in the RFA+sorafenib group had longer 1-,2-,and 3-year overall survival(all p<0.05),better overall efficacy(p<0.0001),longer radiofrequency interval(p<0.001),and lower 2-year recurrence rate(p=0.02).The 1-year overall survival(p=0.003)and overall efficacy(p=0.002)of the MWA+sorafenib group were also higher than those of the MWA-alone group.The incidences of adverse reactions in the RFA+sorafenib group,such as hand-foot skin reactions(p<0.001),diarrhea and constipation(p=0.0001),hypertension(p=0.009),and alopecia(p<0.001),were significantly higher than those in the RFA-alone group.Conclusions:RFA or MWA combined with sorafenib has produced a better therapeutic effect on HCC than physical thermal ablation alone;however,adverse reactions have been obvious.It is necessary to evaluate the safety of combination therapy,and pay close attention to the adverse reactions that develop in patients. | Mengdi Jin Qiong Yu Yahui Liu Weiling Xu Xueqi Fu Bai Ji | 2021 | Journal of Clinical and Translational Hepatology2021，9，2： | 6 |
| 6 | Variability of microphysical characteristics in the “21·7” Henan extremely heavy rainfall event显示文摘In this study, significant rainfall microphysical variability is revealed for the extremely heavy rainfall event over Henan Province in July 2021(the “21·7” Henan EHR event) using a dense network of disdrometers and two polarimetric radars.The broad distributions of specific drop size distribution(DSD) parameters are identified in heavy rainfall from the disdrometer observations, indicating obvious microphysical variability on the surface. A K-means clustering algorithm is adopted to objectively classify the disdrometer datasets into separate groups, and distinct DSD characteristics are found among these heavy rainfall groups. Combined with the supporting microphysical structures obtained through radar observations, comprehensive microphysical features of the DSD groups are derived. An extreme rainfall group is dominantly formed in the deep convection over the plain regions, where the high number of concentrations and large mean sizes of surface raindrops are underpinned by both active ice-phase processes and efficient warm-rain collision-coalescence processes in the vertical direction. Convection located near orographic regions is characterized by restricted ice-phase processes and high coalescence efficiency of liquid hydrometeors, causing the dominant DSD group to comprise negligible large raindrops. Multiple DSD groups can coexist within certain precipitation episodes at the disdrometer stations, indicating the potential microphysical variability during the passage of convective system on the plain regions. | Gang CHEN Kun ZHAO Yinghui LU Yuanyuan ZHENG Ming XUE Zhe-Min TAN Xin XU Hao HUANG Haonan CHEN Fen XU Ji YANG Shushi ZHANG Xueqi FAN | 2022 | Science China Earth Sciences2022，65，10： | 4 |
| 7 | Chlorogallate(Ⅲ) ionic liquids: Synthesis, acidity determination and their catalytic performances for isobutane alkylation显示文摘A series of triethylammonium-based chlorogallate(Ⅲ) ionic liquids with varied Lewis acidity was synthesized, characterized, and firstly applied to isobutane alkylation. The [Et3NHCl]-GaCl3 with χGaCl3 = 0.65 displayed a potential catalytic activity for the alkylation. The addition of copper halide into the chlorogallate(Ⅲ) ionic liquids dramatically enhanced the alkylation reaction. Up to 70.1% C8 selectivity and 91.3 RON were achieved with the [Et3NHCl]-GaCl3-CuCl (χGaCl3 = 0.65, CuCl = 5% mol) under 0.5 MPa, 900 r/min, 15 min, 288 K using the industrial C4 cut (isobutane/butene = 10). These results indicate that the chlorogallate(Ⅲ) system may be used as a promising catalyst for the C4 alkylation. | XING XueQi ZHAO GuoYing CUI JianZhong | 2012 | Science China Chemistry2012，55，8： | 3 |
| 8 | Spatial analysis of land use change effect on soil organic carbon stocks in the eastern regions of China between 1980 and 2000显示文摘Spatial distributions of 0-20 cm soil carbon sources/sinks caused by land use changes from the year 1980 to 2000 in an area of 2.97 × 10~6 km^2 in eastern China were investigated using a land use dataset from a recent soil geochemical survey.A map of soil carbon sources/sinks has been prepared based on a spatial analysis scheme with GIS.Spatial statistics showed that land use changes had caused 30.7 ± 13.64 Tg of surface soil organic carbon loss,which accounts for 0.33%of the total carbon storage of 9.22 Pg.The net effect of the carbon source was estimated to be ~ 71.49 Tg soil carbon decrease and ~40.80 Tg increase.Land use changes in Northeast China(NE) have the largest impact on soil organic carbon storage compared with other regions.Paddy fields,which were mainly transformed into dry farmland in NE,and constructed land in other regions,were the largest carbon sources among the land use types.Swamp land in NE was also another large soil carbon source when it was transformed into dry farmland or paddy fields.Dry farmland in the NE region formed the largest soil organic carbon sink,as some were transformed into paddy fields,forested land,and other land use types with high SOCD. | Xueqi Xia Zhongfang Yang Yuan Xue Xin Shao Tao Yu Qingye Hou | 2017 | Geoscience Frontiers2017，8，3： | 3 |
| 9 | Burden of Disease Due to Cancer——China,2000-2019显示文摘Summary What is already known about this topic?Cancer is a major global public health problem and the leading cause of death in China.China has a large population,and therefore has a significant proportion of the global burden of cancer.What is added by this report?The age-standardized incidence of cancer has increased in China,while the cancer mortality rate has decreased.Compared with younger age groups,individuals over 70 have a greater burden of cancer.Digestive tract cancer and breast cancer should be targeted for prevention,treatment,and control. | Xueqi Fan Bin Zhang Yuan He Xiaolong Zhou Yingying Zhang Li Ma Xudong Li Jing Wu | 2022 | China CDC weekly2022，4，15： | 3 |
| 10 | Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes显示文摘HBV is considered as a“stealth”virus that does not invoke interferon(IFN)responses;however,the mechanisms by which HBV bypasses innate immune recognition are poorly understood.In this study,we identified adenosine deaminases acting on RNA 1(ADAR1),which is a key factor in HBV evasion from IFN responses in hepatocytes.Mechanically,ADAR1 interacted with HBV RNAs and deaminated adenosine(A)to generate inosine(I),which disrupted host immune recognition and thus promoted HBV replication.Loss of ADAR1 or its deficient deaminase activity promoted IFN responses and inhibited HBV replication in hepatocytes,and blocking the IFN signaling pathways released the inhibition of HBV replication caused by ADAR1 deficiency.Notably,the HBV X protein(HBx)transcriptionally promoted ADAR1 expression to increase the threshold required to trigger intrinsic immune activation,which in turn enhanced HBV escape from immune recognition,leading to persistent infection.Supplementation with 8-azaadenosine,an ADAR1 inhibitor,efficiently enhanced liver immune activation to promote HBV clearance in vivo and in vitro.Taken together,our results delineate a molecular mechanism by which HBx promotes ADAR1-derived HBV immune escape and suggest a targeted therapeutic intervention for HBV infection. | Liyuan Wang Yang Sun Xiaojia Song Zehua Wang Yankun Zhang Ying Zhao Xueqi Peng Xiaodong Zhang Chunyang Li Chengjiang Gao Nailin Li Lifen Gao Xiaohong Liang Zhuanchang Wu Chunhong Ma | 2021 | Cellular & Molecular Immunology2021，18，8： | 2 |
| 11 | Oxymatrine Inhibits Bocavirus MVC Replication, Reduces Viral Gene Expression and Decreases Apoptosis Induced by Viral Infection显示文摘Oxymatrine(OMT), as the main active component of Sophoraflavescens, exhibits a variety of pharmacological properties,including anti-oxidative, anti-inflammatory, anti-tumor, and anti-viral activities, and currently is extensively employed to treat viral hepatitis; however, its effects on parvovirus infection have yet to be reported. In the present study, we investigated the effects of OMT on cell viability, virus DNA replication, viral gene expression, cell cycle, and apoptosis in Walter Reed canine cells/3873 D infected with minute virus of canines(MVC). OMT, at concentrations below 4 mmol/L(no cellular toxicity), was found to inhibit MVC DNA replication and reduce viral gene expression at both mRNA and protein levels, which was associated with the inhibition of cell cycle S-phase arrest in early-stage of MVC infection.Furthermore, OMT significantly increased cell viability, decreased MVC-infected cell apoptosis, and reduced the expression of activated caspase 3. Our results suggest that OMT has potential application in combating parvovirus infection. | Yanqin Ding Na Li Jinhan Sun Linran Zhang Jianhui Guo Xueqi Hao Yuning Sun | 2019 | Virologica Sinica2019，34，1： | 2 |
| 12 | SOD1^(G93A) Induces a Unique PSAP-Dependent Mitochondrial Apoptosis Pathway via Bax-Bak Interaction显示文摘Amyotrophic lateral syndrome(ALS)is a progressive degenerative disorder characterized by motor neuron death and axon degeneration.Mitochondrial dysfunction plays a key role in the pathogenesis of ALS,the mechanism of which remains poorly understood.The B-cell lymphoma-2(Bcl-2)family of proteins that control and mediate mitochondrial function and apoptosis,including the pro-apoptotic members Bcl2-Associated X(Bax),are involved in ALS development.The death receptor 6(DR6)regulates motor neuron death in ALS,and DR6 antibodies can prevent axon degeneration and motor neuron damage by blocking DR6.Previous studies demonstrated that PSAP localized to mitochondria and was required for DR6-induced apoptosis.In this study,SOD1^(G93A) was transfected into the motor neuron cell line NSC-34 to serve as an ALS cell model in vitro.The data assessed the role of PSAP in SOD1^(G93A)induced apoptosis and demonstrated that the overexpression of SOD1^(G93A),but not wtSOD1,induced PARP cleavage,caspase-3 activation,cytochrome c release,and Bax translocation.PSAP,Bax,and Bak were necessary for SOD1^(G93A)induced apoptosis,as silencing PSAP inhibited SOD1^(G93A)-mediated cell death that was dependent on Bax-Bak interaction. | HAN NIU XIN CHEN XUEQI FU JINGTIAN ZHANG GUODONG LI YUXIANG WANG JIAYUE SONG XUETING MA CHEN HU XUEMIN XU FUQIANG ZHANG LINLIN ZENG | 2021 | BIOCELL2021，45，4： | 2 |
| 13 | Simultaneous nitrification and denitrification by aerobic granular sludge membrane bioreactor for high concentration ammonium nitrogen wastewater显示文摘 | Rui CHEN Xiaoli WANG Yonggang ZHANG Xueqi FU | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 2 |
| 14 | Combating emerging financial risks in the big data era:A perspective review显示文摘financial services:for example,GPS and Bluetooth inspire location-based services,and search and web technologies motivate online shopping,reviews,and payments.These business services have become more connected than ever,and as a result,financial frauds have become a significant challenge.Therefore,combating financial risks in the big data era requires breaking the borders of traditional data,algorithms,and systems.An increasing number of studies have addressed these challenges and proposed new methods for risk detection,assessment,and forecasting.As a key contribution,we categorize these works in a rational framework:first,we identify the data that can be used to identify risks.We then discuss how big data can be combined with the emerging tools to effectively learn or analyze financial risk.Finally,we highlight the effectiveness of these methods in real-world applications.Furthermore,we stress on the importance of utilizing multi-channel information,graphs,and networks of long-range dependence for the effective identification of financial risks.We conclude our survey with a discussion on the new challenges faced by the financial sector,namely,deep fake technology,adversaries,causal and interpretable inference,privacy protection,and microsimulations. | Xueqi Cheng Shenghua Liu Xiaoqian Sun Zidong Wang Houquan Zhou Yu Shao Huawei Shen | 2021 | Fundamental Research2021，1，5： | 2 |
| 15 | Primary tumor location in lung cancer:the evaluation and administration显示文摘Lung cancer continues to be the leading cause of cancer-related death in the world,which is classically subgrouped into two major histological types:Non-small cell lung cancer(NSCLC)(85%of patients)and small-cell lung cancer(SCLC)(15%).Tumor location has been reported to be associated with the prognosis of various solid tumors.Several types of cancer often occur in a specific region and are more prone to spread to predilection locations,including colorectal cancer,prostate cancer,gastric cancer,ovarian cancer,cervical cancer,bladder cancer,lung tumor,and so on.Besides,tumor location is also considered as a risk factor for lung neoplasm with chronic obstructive pulmonary disease/emphysema.Additionally,the primary lung cancer location is associated with specific lymph node metastasis.And the recent analysis has shown that the primary location may affect metastasis pattern in metastatic NSCLC based on a large population.Numerous studies have enrolled the“location”factor in the risk model.Anatomy location and lobe-specific location are both important in prognosis.Therefore,it is important for us to clarify the characteristics about tumor location according to various definitions.However,the inconsistent definitions about tumor location among different articles are controversial.It is also a significant guidance in multimode therapy in the present time.In this review,we mainly aim to provide a new insight about tumor location,including anatomy,clinicopathology,and prognosis in patients with lung neoplasm. | Xueqi Xie Xiaolin Li Wenjie Tang Peng Xie Xuefen Tan | 2022 | Chinese Medical Journal2022，，2： | 2 |
| 16 | Detect overlapping and hierarchical community structure in networks显示文摘 | Huawei Shen Xueqi Cheng Kai Cai Mao-Bin Hu | 2008 | Physica A: Statistical Mechanics and its Applications2008，，8： | 2 |
| 17 | Synthesis of organo-modified a-zirconium phosphate and its effect on the flame retardancy of IFR poly(lactic acid) systems 显示文摘 | Liu Xueqi Wang Deyi Wang Xiuli | 2011 | Polymer Degradation and Stability2011，96，： | 1 |
| 18 | Occurrence of endocrine-disrupting compounds in reclaimed water from Tianjin, China显示文摘 | Yuqiu Wang Wei Hu Zhonghong Cao Xueqi Fu Tan Zhu | 2005 | Analytical and Bioanalytical Chemistry2005，，5： | 1 |
| 19 | Fretting wear behaviors of mandibular condylar cartilage of nature temporomandibular joint in vitro显示文摘 | Xueqi Gan Zhenbing Cai Mengting Qiao | 2013 | Tribology International2013，63，2： | 1 |
| 20 | Smart Contract Fuzzing Based on Taint Analysis and Genetic Algorithms显示文摘Smart contract has greatly improved the services and capabilities of blockchain,but it has become the weakest link of blockchain security because of its code nature.Therefore,efficient vulnerability detection of smart contract is the key to ensure the security of blockchain system.Oriented to Ethereum smart contract,the study solves the problems of redundant input and low coverage in the smart contract fuzz.In this paper,a taint analysis method based on EVM is proposed to reduce the invalid input,a dangerous operation database is designed to identify the dangerous input,and genetic algorithm is used to optimize the code coverage of the input,which construct the fuzzing framework for smart contract together.Finally,by comparing Oyente and ContractFuzzer,the performance and efficiency of the framework are proved. | Zaoyu Wei Jiaqi Wang Xueqi Shen Qun Luo | 2020 | Journal of Quantum Computing2020，2，1： | 1 |
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