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| 1 | Effect of Deficit Irrigation on the Growth, Water Use Characteristics and Yield of Cotton in Arid Northwest China显示文摘Water shortage is a key constraint to sustainable agricultural production in Xinjiang, Northwest China. To enhance the use efficiency of valuable irrigation water resources, a 2-year experiment(2010–2011) was conducted to quantify the response of cotton(Gossypium hirsutum L.) growth and yield to different degrees of deficit irrigation(DI) regimes; to determine the effects of DI on the characteristics of water use for cotton, seasonal water use, available soil water in the root zone, soil water depletion, evapotranspiration(ET)-based water use efficiency and irrigation-based water use efficiency, and to determine the best DI regime for optimal water-saving and yield output. The plots were irrigated at 100%(100ET), 85%(85ET), 70%(70ET), 55%(55ET) and 45%(45ET) of the regional ET of cotton in northern Xinjiang. The effect of DI irrigation on water use characteristics was evaluated by analyzing available soil water and soil water depletion in the root zone along with water use efficiencies of cotton. The study showed that the growth, water use characteristics and yield of cotton varied with irrigation regime. Seasonal ET and seed cotton yield were linearly correlated with irrigation amount. The second-order polynomial equation best approximated water-yield relationship of cotton in the study area.Cotton yield response factor was 0.65, suggesting limited water conditions were suitable for cotton cultivation. Economic evaluation of DI treatments confirmed that the yield loss was less than 10% under 70 ET and 85 ET, which was acceptable for greater sustainability.The results suggested that proper DI schemes were necessary for sustainable cotton production in the region. While irrigation at 85 ET was safe for high cotton yield, irrigation at 70 ET was a viable alternative under limited irrigation water availability. | YANG Chuanjie LUO Yi SUN Lin WU Na | 2015 | Pedosphere2015，25，6： | 17 |
| 2 | An analytical biomarker for treatment of patients with recurrent B-ALL after remission induced by infusion of anti-CD19 chimeric antigen receptor T(CAR-T) cells显示文摘Anti-CD19 chimeric antigen receptor-modified T(CAR-T-19) cells have emerged as a powerful targeted immunotherapy for B-cell lineage acute lymphoblastic leukemia with a remarkable clinical response in recent trials. Nonetheless, few data are available on the subsequent clinical monitoring and treatment of the patients, especially those with disease recurrence after CAR-T-19 cell infusion. Here, we analyzed three patients who survived after our phase I clinical trial and who were studied by means of biomarkers reflecting persistence of CAR-T-19 cells in vivo and predictive factors directing further treatment. One patient achieved 9-week sustained complete remission and subsequently received an allogeneic hematopoietic stem cell transplant. Another patient who showed relapse after 20 weeks without detectable leukemia in the cerebrospinal fluid after CAR-T-19 cell treatment was able to achieve a morphological remission under the influence of stand-alone low-dose chemotherapeutic agents. The third patient gradually developed extensive extramedullary involvement in tissues with scarce immune-cell infiltration during a long period of hematopoietic remission after CAR-T-19 cell therapy. Long-term and discontinuous increases in serum cytokines(mainly interleukin 6 and C-reactive protein) were identified in two patients(Nos. 1 and 6) even though only a low copy number of CAR molecules could be detected in their peripheral blood. This finding was suggestive of persistent functional activity of CAR-T-19 cells. Combined analyses of laboratory biomarkers with their clinical manifestations before and after salvage treatment showed that the persistent immunosurveillance mediated by CAR-T-19 cells would inevitably potentiate the leukemia-killing effectiveness of subsequent chemotherapy in patients who showed relapse after CAR-T-19-induced remission. | Yajing Zhang Wenying Zhang Hanren Dai Yao Wang Fengxia Shi Chunmeng Wang Yelei Guo Yang Liu Meixia Chen Kaichao Feng Yan Zhang Chuanjie Liu Qingming Yang Suxia Li Weidong Han | 2016 | Science China(Life Sciences)2016，59，4： | 6 |
| 3 | Mutation of the PHYTOENE DESATURASE 3 gene causes yellowish-white petals in Brassica napus显示文摘Oilseed rape (Brassica napus) with yellow flowers is an attractive ornamental landscape plant during the flowering period,and the development of different petal colors has become a breeding objective.Although yellowish flower color is a common variant observed in field-grown oilseed rape,the genetics behind this variation remains unclear.We obtained a yellowish-white flower (ywf) mutant from Zhongshuang 9 (ZS9) by ethyl methanesulfonate mutagenesis (EMS) treatment.Compared with ZS9,ywf exhibited a lower carotenoid content with a reduced and defective chromoplast ultrastructure in the petals.Genetic analysis revealed that the yellowish-white trait was controlled by a single recessive gene.Using bulked-segregant analysis sequencing (BSA-seq) and kompetitive allele-specific PCR(KASP),we performed map-based cloning of the ywf locus on chromosome A08 and found that ywf harbored a C-to-T substitution in the coding region,resulting in a premature translation termination.YWF,encoding phytoene desaturase 3 (PDS3),was highly expressed in oilseed rape petals and involved in carotenoid biosynthesis.Pathway enrichment analysis of the transcriptome profiles from ZS9 and ywf indicated the carotenoid biosynthesis pathway to be highly enriched.Further analyses of differentially expressed genes and carotenoid components revealed that the truncated Bna A08.PDS3 resulted in decreased carotenoid biosynthesis in the mutant.These results contribute to an understanding of the carotenoid biosynthesis pathway and manipulation of flower-color variation in B.napus. | Chuanji Zhao Luqman Bin Safdar Meili Xie Meijuan Shi Zhixue Dong Li Yang Xiaohui Cheng Yueying Liu Zetao Bai Yang Xiang Chaobo Tong Junyan Huang Lijiang Liu Shengyi Liu | 2021 | The Crop Journal2021，9，5： | 3 |
| 4 | Association between fluid-attenuated inversion recovery vascular hyperintensity and outcome varies with different lesion patterns in patients with intravenous thrombolysis显示文摘Background and purpose To evaluate relationship between fluid-attenuated inversion recovery vascular hyperintensity(FVH)after intravenous thrombolysis and outcomes in different lesion patterns on diffusion-weighted imaging(DWI).Methods Patients with severe internal carotid or intracranial artery stenosis who received intravenous thrombolysis from March 2012 to April 2019 were analysed.They were divided into four groups by DWI lesion patterns:border-zone infarct(BZ group),multiple lesions infarct(ML group),large territory infarct(LT group),and single cortical or subcortical lesion infarct(SL group).Logistic regression was performed to identify risk factors for outcome(unfavourable outcome,modified Rankin Scale(mRS)≥2;poor outcome,mRS≥3).Results Finally,203 participants(63.3±10.2 years old;BZ group,n=72;ML group,n=64;LT group,n=37;SL group,n=30)from 1190 patient cohorts were analysed.After adjusting for confounding factors,FVH(+)was associated with unfavourable outcome in total group(OR 3.02;95%CI 1.49 to 6.13;p=0.002),BZ group(OR 4.22;95%CI 1.25 to 14.25;p=0.021)and ML group(OR 5.44;95%CI 1.41 to 20.92;p=0.014)patients.FVH(+)was associated with poor outcome in total group(OR 2.25;95%CI 1.01 to 4.97;p=0.046),BZ group(OR 5.52;95%CI 0.98 to 31.07;p=0.053)and ML group(OR 4.09;95%CI 1.04 to 16.16;p=0.045)patients,which was marginal significance.FVH(+)was not associated with unfavourable or poor outcome in LT and SL groups.Conclusion This study suggests that association between FVH and outcome varies with different lesion patterns on DWI.The presence of FVH after intravenous thrombolysis may help to identify patients who require close observations in the hospitalisation in patients with border-zone and multiple lesion infarcts. | Erling Wang Chuanjie Wu Dandan Yang Xihai Zhao Jie Zhao Hong Chang Qi Yang | 2021 | Stroke & Vascular Neurology2021，6，3： | 3 |
| 5 | De novo design of future rapeseed crops:Challenges and opportunities显示文摘To address the global demand for rapeseed while considering farmers’profit,we face the challenges of making a quantum leap in seed yield and,at the same time,reducing yield loss due to biotic and abiotic stresses.We also face the challenge of efficiently applying new transformative biotechnology tools such as gene editing and breeding by genome design to increase rapeseed productivity and profitability.In this Perspective,we review advances in research on the physiological and genetic bases of both stress factorsaffected yield stability and seed yield potential,focusing on source–sink relationships and allocation of photosynthetic assimilates to vegetative growth and seed development.We propose research directions and highlight the role of plant architecture in the relative contributions of the root system,leaves,and pods to seed yield.We call for de novo design of new rapeseed crops.We review trait variation in existing germplasm and biotechnologies available for crop design.Finally,we discuss opportunities to apply fundamental knowledge and key germplasm to rapeseed production and propose an ideotype for de novo design of future rapeseed cultivars. | Shengyi Liu Harsh Raman Yang Xiang Chuanji Zhao Junyan Huang Yuanyuan Zhang | 2022 | The Crop Journal2022，10，3： | 2 |
| 6 | Diurnal expression of circadian clock genes period 1 and period 3 in Pelteobagrus vachellii显示文摘Circadian clock genes are crucial for generating and sustaining most rhythmic daily functions in the animal kingdom,which entrain the rhythms of biochemical,physiological,and behavioural processes.To better understand the molecular oscillations of the circadian rhythms in darkbarbel catfish(Pelteobagrus vachellii),we isolated and characterized two circadian clock genes in P.vachellii,period 1(per1),and period 3(per3).The circadian clock gene per1 was found to encode a 1428-amino acid polypeptide,including PER-ARNT-SIM(PAS)dimerisation domains,a PAS-associated C-terminal motif(PAC),a short mutable domain(S/M),and a nuclear export signal(NES).The 4902-bp per3 cDNA includes an open reading frame encoding a 1292-amino acid residue polypeptide with a PER-ARNT-SIM(PAS)domain,cytoplasmic localisation domain(CLD),interaction site(TIS),and a nuclear localisation signal(NLS).The per1 and per3 gene was constitutively expressed in all examined tissues.Moreover,per1 expression within a light/dark cycles showed rhythmic expression in the diencephalon,brain,liver and intestine,with the acrophase at 15:15,12:52,7:51 and 12:55,respectively.Daily expression of per3 was rhythmic in the diencephalonbrain,liver and intestine,with the acrophase at 8:15,9:54,10:39,and 10:25 h,respectively.These findings expand our understanding of circadian mechanism at the molecular level in this species. | Chuanjie QIN Ting SHAO Xufeng LIAO Yang HE Jun WANG Peng HU | 2021 | Journal of Oceanology and Limnology2021，39，2： | 1 |
| 7 | Effects of Plant Community Type on Soil Methane Flux in Semiarid Loess Hilly Region,Central Gansu Province,China显示文摘Methane(CH_(4))is an important greenhouse gas second only to CO_(2)in terms of its greenhouse effect.Vegetation plays an important role in controlling soil CH_(4)fluxes,but the spatial variability of soil CH_(4)fluxes during vegetation restoration in Loess Hilly Region(LHR)is not fully understood.The effects of different plant community types[Medicago sativa grassland(MS);Xanthoceras sorbifolium forestland(XS);Caragana korshinskii bushland(CK);Hippophae rhamnoides shrubland(HR);and Stipa bungeana grassland(SB)]on soil CH_(4)flux in LHR were studied via the static chamber technique.The results showed that the five plant community types were sinks of soil CH_(4)in LHR,the plant community type significantly affected the soil CH_(4)flux,and the average CH_(4)uptake from high to low was in SB,HR,CK,MS,and XS.During the whole study period,the soil CH_(4)flux showed similar interannual variation.The maximum absorption of soil CH_(4)appeared in the growing season,while the minimum appeared in winter.Soil CH_(4)uptake was positively correlated with soil temperature and soil moisture.Soil temperature and moisture are important controlling factors for the temporal variability of soil CH_(4)flux.In LHR,the Stipa bungeana grassland is the more suitable plant community type for reducing soil CH_(4)emissions.In the process of vegetation restoration in LHR,the soil CH_(4)absorption potential of different plant community types should be considered,ecological benefits should be taken into account,and vegetation more suitable for mitigating the greenhouse effect should be selected. | Chuanjie YANG Guang LI Lijuan YAN Weiwei MA Jiangqi WU Yan TAN Shuainan LIU Shikang ZHANG | 2022 | Advances in Atmospheric Sciences2022，39，8： | 1 |
| 8 | Corrigendum to“De novo design of future rapeseed crops:Challenges and opportunities”[Crop J.10(2022)587-596]显示文摘The authors regret to report some mistakes in the text and associated changes necessary to section 4.1 of the paper.On page 591 in the right-hand column,line 34,“far light”should be changed to“far-red light”.On page 592 in the left-hand column,line 28,the sentence reads:“If the YP/FP ratio can be as high as 42%(the average YP/FP of the UK and China.Table S2),the farm yield will be 5.0 t ha1.” | Shengyi Liu Harsh Raman Yang Xiang Chuanji Zhao Junyan Huang Yuanyuan Zhang | 2022 | The Crop Journal2022，10，4： | 0 |
| 9 | Patterning of large area nanoscale domains in as-grown epitaxial ferroelectric PbTiO_(3)films显示文摘Effective tuning of nanoscale domain structures provides fundamental basis for controlling and engineering of various functionalities in ferroelectric materials.In this work,we demonstrate the precise patterning of nanoscopic domain structures in as-grown epitaxial PbTiO_(3)(PTO)films by merely introducing an ultrathin pre-patterned doping layer(e.g.,Fe-doped PTO).The doping layer can effectively reverse the interfacial built-in bias,consequent to a reversed initial polarization reorientation in the as-grown film,which makes it possible to transfer the nano-patterns in the doping layer into the domain structure of ferroelectric films.For instance,we have successfully fabricated large area ordered array of nanoscale cylindrical domains(downward polarization)embedded in the matrix domain with opposite polarization(upward polarization)in PTO film.These nanoscale cylinder domains also allow deterministic and reversible erasure and creation induced by biased tip scanning.The results provide an effective pathway for on-demand patterning of large area nanoscale domains in the as-grown films,which may find applications in a wide range of nanoelectronic devices. | Luyong Zhang Guo Tian Wenda Yang Dongfeng Zheng Chuanjie Lin Jianbiao Xian Yihang Guo Xingchen Zhang Xiuqin Qiu Lanping Zhang Zhen Fan Deyang Chen Zhipeng Hou Minghui Qin Jun-Ming Liu Xingsen Gao | 2023 | Journal of Materiomics2023，9，1： | 0 |
| 10 | Genome-wide association study exposed the pleiotropic genes for yield-related and oil quality traits in Brassica napus L.显示文摘Oilseed rape(Brassica napus L.) is an allotetraploid(AACC,2n=38) crop,valued for its edible oil and protein content.seed yield and nutritional composition of rapeseed are influenced by its yield and oil quality traits.However,the genetic basis of yield-related and oil-quality traits remain ambiguous.A panel of 266 diversified oilseed rape accessions was genotyped using 223 simple sequence repeat(SSR) markers covering all 19 chromosomes to identify significant markers associated with yield and quality traits.Twelve yield-related and six quality traits were investigated in two consecutive years(2014 and 2015),with three replications in two environments(Changshun,CS;and Qinghe,QH).Using the model GLM with population structure and kinship(Q+K),a total of 25 significant SSR markers(P <0.001) were detected to be associated with these twelve yield-related and six quality traits,explaining 4.56%-19.17% of the phenotypic variation for each trait.Based on these markers,BnaA03g23490D, BnaC09g46370D,BnaA07g37150D,BnaA01g32590D, and BnaC09g37280D were identified as pleiotropic genes controlling multiple traits.These candidate genes illustrated the potential for the genetic understanding of yield and oil quality traits.Most importantly,these significant markers can be used for marker-assisted breeding of oilseed rape in different environments. | Yang Xiang M.M.U.Helal Longbing Liang Minqin Zhang Hongshi Han Xianglai Dai Jixian Zhao Dalun Chen Xianping Wang Min Li Chuanji Zhao | 2023 | Oil Crop Science2023，8，3： | 0 |
| 11 | Dual-sized hollow particle incorporated fibroin thermal insulating coatings on catheter for cerebral therapeutic hypothermia显示文摘Selective endovascular hypothermia has been used to provide cooling-induced cerebral neuroprotection,but current catheters do not support thermally-insulated transfer of cold infusate,which results in an increased exit temperature,causes hemodilution,and limits its cooling efficiency.Herein,air-sprayed fibroin/silica-based coatings combined with chemical vapor deposited parylene-C capping film was prepared on catheter.This coating features in dual-sized-hollow-microparticle incorporated structures with low thermal conductivity.The infusate exit temperature is tunable by adjusting the coating thickness and infusion rate.No peeling or cracking was observed on the coatings under bending and rotational scenarios in the vascular models.Its efficiency was verified in a swine model,and the outlet temperature of coated catheter(75μm thickness)was 1.8-2.0◦C lower than that of the uncoated one.This pioneering work on catheter thermal insulation coatings may facilitate the clinical translation of selective endovascular hypothermia for neuroprotection in patients with acute ischemic stroke. | Ming Li Yuan Gao Miaowen Jiang Hongkang Zhang Yang Zhang Yan Wu Wenhao Zhou Di Wu Chuanjie Wu Longfei Wu Luzi Bao Xiaoxiao Ge Zhengfei Qi Ming Wei Ang Li Yuchuan Ding Jicheng Zhang Guangzhen Pan Yu Wu Yan Cheng Yufeng Zheng Xunming Ji | 2023 | Bioactive Materials2023，，8： | 0 |
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