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| 1 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 2 | Effects of dietary fiber on human health显示文摘Dietary fiber(DF)is believed to provide important health benefits and it has become a research hotspot.DF exists in most natural foods,including fruits(16.74%-91.24%),vegetables(6.53%-85.19%),grains(9.76%-69.20%)and so on.DF has different physicochemical properties such as water holding capacity(WHC)(2.01-25.03 g/g),water swelling capacity(WSC)(0.95-23.90 mL/g),oil holding capacity(OHC)(0.65-29.00 g/g),glucose adsorption capacity(GAC)(0.17-4.65 mmol/g),cholesterol adsorption capacity(CAC)(0.03-37.10 mg/g)and viscosity,which make it exhibits different physiological functions such as reducing the risk of obesity,diabetes,cancer,and intestinal diseases.On the basis of consulting related databases,the physicochemical properties of DF and its derived physiological functions are reviewed.It is found that DF has effect on the prevention and treatment of obesity due to good WHC,WSC,OHC and CAC.Good GAC can relieve the symptoms of diabetes.The physicochemical properties of WHC and WSC can reduce the risk of cancer.The WHC,WSC and viscosity are beneficial to intestinal health. | Yang He Bixiang Wang Liankui Wen Fengzhong Wang Hansong Yu Dongxia Chen Xin Su Chi Zhang | 2022 | Food Science and Human Wellness2022，11，1： | 15 |
| 3 | Catalyst-Free Growth of Nanographene Films on Various Substrates显示文摘我们开发了一个新方法在各种各样的底层上直接种一致 graphene 电影,例如绝缘体,半导体,甚至金属,没有使用任何催化剂。生长用遥远的血浆改进化学药品蒸汽免职(r-PECVD ) 被执行在相对低的温度的系统,启用 graphene 电影的免职直到 4 英寸的晶片规模。扫描通道显微镜学(STM ) 证实电影由在侧面的尺寸的十纳米的 nanocrystalline graphene 粒子组成。为 nanographene 的生长机制为 PECVD 方法种的钻石类似于那,尽管有在 graphene 的情况中被形成的 sp2 碳原子而非象在钻石的 sp3 碳原子。这条生长途径简单、便宜、可伸缩,并且可能在象薄电影电阻器,煤气的传感器,电极材料,和透明传导性的电影那样的域里有潜在的应用程序。 | Lianchang Zhang Zhiwen Shi Yi Wang Rong Yang Dongxia Shi Guangyu Zhang | 2011 | Nano Research2011，4，3： | 12 |
| 4 | Increased activity of MdFRK2, a high-affinity fructokinase, leads to upregulation of sorbitol metabolism and downregulation of sucrose metabolism in apple leaves显示文摘To investigate the functions of fructokinase(FRK)in apple(Malus domestica)carbohydrate metabolism,we cloned the coding sequences of MdFRK1 and MdFRK2 from the‘Royal Gala’apple.The results showed that MdFRK2 expression was extremely high in shoot tips and young fruit.Analyses of heterologously expressed proteins revealed that MdFRK2 had a higher affinity for fructose than did MdFRK1,with Km values of 0.1 and 0.62 mM for MdFRK2 and MdFRK1,respectively.The two proteins,however,exhibited similar Vmax values when their activities were significantly inhibited by high concentrations of fructose.MdFRK2 ectopic expression was associated with a general decrease in fructose concentration in transgenic lines.In leaves,increased FRK activity similarly resulted in reduced concentrations of glucose and sucrose but no alterations in sorbitol concentration.When compared with those in the untransformed control,genes involved in sorbitol synthesis(A6PR)and the degradation pathway(SDH1/2)were significantly upregulated in transgenic lines,whereas those involved in sucrose synthesis(SPS1)and other degradation processes(SUSY4,NINV1/2,and HxK2)were downregulated.The activity of enzymes participating in carbohydrate metabolism was proportional to the level of gene expression.However,the growth performance and photosynthetic efficiency did not differ between the transgenic and wild-type plants.These results provide new genetic evidence to support the view that FRK plays roles in regulating sugar and sorbitol metabolism in Rosaceae plants. | Jingjing Yang Lingcheng Zhu Weifang Cui Chen Zhang Dongxia Li Baiquan Ma Lailiang Cheng Yong-Ling Ruan Fengwang Ma Mingjun Li | 2018 | Horticulture Research2018，5，1： | 9 |
| 5 | Curative effect of scraping therapies on lumbar muscle strain显示文摘OBJECTIVE:To explore factors influencing the curative effect of scraping therapies (at acupoints or along channels) and to determine the relationship of scraping site and strength to curative effect. METHODS: Two hundred and ten patients with lumbar muscle strain were divided into five groups with 42 patients each.The 'scraping therapy at acupoint until appearance of skin eruptions' and 'scraping therapy along channel until appearance of skin eruptions' groups were treated with a 4-daycourse. The 'scraping therapy at acupoint without appearance of skin eruptions', 'scraping therapy along channel without appearance of skin eruptions', and acupuncture groups were treated with a 2-day course.The five groups were treated with seven courses. The visual analog scale (VAS), oswestry disability index (ODI), and lumbago scores were recorded in the five groups before treatment, after each treatment, and in follow-up visits one month and three months after treatment. RESULTS: VAS, ODI, and lumbago scores after treatment improved in the five groups (P<0.01). There was a statistical difference (P<0.01) in the change of VAS scores by appearance of skin eruptions and scraping site. CONCLUSION: Scraping therapy can effectively alleviate lumbago symptoms. The appearance of skin eruptions and scraping therapy along channels can enhance the curative effect of scraping therapy. | Yingying Wang Li Yang Jinsheng Yang Jinhong Yang Zhibin Liu Feng Chen Dongxia Liu Haiguang Yuan Liang Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 7 |
| 6 | The lightning activities in super typhoons over the Northwest Pacific显示文摘The spatial and temporal characteristics of lightning activities have been studied in seven super typhoons from 2005 to 2008 over the Northwest Pacific, using data from the World Wide Lightning Location Network (WWLLN). The results indicated that there were three distinct lightning flash regions in mature typhoon, a significant maximum in the eyewall regions (20-80 km from the center), a minimum from 80-200 km, and a strong maximum in the outer rainbands (out of 200 km from the center). The lightning flashes in the outer rainbands were much more than those in the inner rainbands, and less than 1% of flashes occurred within 100 km of the center. Each typhoon produced eyewall lightning outbreak during the periods of its intensification, usually several hours prior to its maximum intensity, indicating that lightning activity might be used as a proxy of intensification of super typhoon. Little lightning occurred near the center after landing of the typhoon. | PAN LunXiang QIE XiuShu LIU DongXia WANG DongFang YANG Jing | 2010 | Science China Earth Sciences2010，53，8： | 7 |
| 7 | Molecular intrinsic characteristic contours of small organic molecules containing oxygen atom显示文摘By utilizing the classical turning point of the electron movement, we have defined and computed the mo-lecular intrinsic characteristic contour (MICC) via the com-bination of the ab initio quantum chemistry computational method with the ionization potential measured by photo-electron spectroscopy experiment. In this paper, we calcu-lated the MICCs of several small organic molecules contain-ing oxygen atom for the first time. The three-dimensional pictures have been drawn, by performing a large number of calculations. The analysis on some characterized cross-sec-tions of the MICC can provide atomic spatial changing information in the process of forming a molecule. | GONG Lidong ZHAO Dongxia YANG Zhongzhi | 2003 | Chinese Science Bulletin2003，48，18： | 4 |
| 8 | Theoretical study on characteristic ionic radii显示文摘The characteristic radii for univalent cations and anions were defined by the classical turning point of the electron movement in an ion. The numerical results of the elements from first- to third-rows in the periodic table were obtained using %ab initio% method. The results correlate quite well with Pauling ionic radii and Shannon and Prewitt ionic radii. | Zhongzhi Yang Guohui Li Dongxia Zhao Hongbin He Renan Sun | 1998 | Chinese Science Bulletin1998，43，17： | 4 |
| 9 | Solvent extraction and separation of light rare earths from chloride media using HDEHP-P350 system显示文摘Solvent extraction is the most important method for rare earth extraction and separation.Currently,di(2-ethylhexyl)phosphoric acid(HDEHP)and 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester(HEH/EHP)are widely used in industrial production,but there are still obvious deficiencies that require further research to resolve.In this paper,the unsaponification extraction of light rare earth ions in a hydrochloric acid medium by di(2-ethylhexyl)phosphoric acid-di(1-methyl-heptyl)methyl phosphonate(HDEHPP350)system was studied.The results show that the addition of P350 reduces the extraction capacity of HDEHP,and also greatly reduces the concentration of acidity required for the back-extraction.It still has a good separation factor for light rare earths without saponification,and the extractant is not easy to emulsify.With an aqueous phase of pH=2.85,and HDEHP mole fraction XHDEHP=0.9(compared with O/A=2),the separation effect of light rare earth is the best,resulting in the separation coefficientβCe/La=3.39,βPr/Ce=1.67 andβNd/Pr=1.45,respectively.The loaded light rare earth ions extracted by HDEHP-P350 can be easily stripped when 2 mol/L HCl is used as the stripping agent.Finally,the extraction mechanism is discussed using a slope method,and the final structure of the extracted complex is determined to be RECl[(DEHP)_(2)]_(2)P350_((o)),based on a combination of infrared spectra and 1 H NMR and 31P NMR analyses. | Wenjie Zhang Dongxia Feng Xian Xie Xiong Tong Yunpeng Du Yang Cao | 2022 | Journal of Rare Earths2022，40，2： | 3 |
| 10 | Exploration of the potential acting on an electron within diatomic molecules显示文摘The potential acting on an electron within a molecule (PAEM) is formulated, and then calculated using the ab initio MELD program plus a separate calculation program in the RHF molecular orbital theory, finally the three-dimensional graphs of the potentials have been drawn. We have systematically investigated this kind of the potentials for a series of the diatomic molecules, such as HF, HCl, HBr, LiF, LiCl, and so on. The three-dimensional graph can clearly display the variation of the potential felt by an electron within a molecule and get a deeper understanding of the electronic motion and chemical bonding within a molecule. | ZHAO Dongxia GONG Lidong YANG Zhongzhi | 2002 | Chinese Science Bulletin2002，47，8： | 3 |
| 11 | Surface phase defects induced downstream laser intensity modulation in high-power laser facility显示文摘Optics surface phase defects induced intensity modulation in high-power laser facility for inertial confinement fusion research is studied. Calculations and experiments reveal an exact mapping of the modulation patterns and the optics damage spot distributions from the surface phase defects. Origins are discussed during the processes of optics manufacturing and diagnostics, revealing potential improvements for future optics manufacturing techniques and diagnostic index, which is meaningful for fusion level laser facility construction and its operation safety. | Xin Zhang Wei Zhou Wanjun Dai Dongxia Hu Xuewei Deng Wanqing Huang Lidan Zhou Qiang Yuan Xiaoxia Huang De'en Wang Ying Yang | 2016 | High Power Laser Science and Engineering2016，4，1： | 2 |
| 12 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016，1，1： | 2 |
| 13 | QM/MM(ABEEM) Study on the Ligand Substitution Processes of Ruthenium(Ill) Complex NAMI-A显示文摘QM combined with ABEEMσπ (atom-bond electronegativity equalization method) fluctuating charge polariza-ble tbrce field [QM/MM(ABEEM)] has been employed to investigate the hydrolysis mechanism of ruthenium(liDcomplex NAMI-A. Eleven possible hydrolysis paths of NAMI-A and its hydrolysates have been unveiled. Struc-tures obtained by QM/MM (ABEEM) method were used to calculate the activation free energy by free energy per-turbation theory. Based on analysis of structures and activation free energies, it is found that the rate of DMSO dis-sociation is faster than that of C1- dissociation in the first step, which is in agreement with experimental results. Hy-drolysates of the first step continue to hydrolyze with lower activation free energies than that of the first hydrolysisstep, but the trans-position CI hydrolysis in the second step needs more time to perform. This can account for ex-perimental phenomenon reasonably. We have simulated further hydrolysis paths of the hydrolysates, then found thatboth CI- dissociation and DMSO dissociation take place in the third hydrolysis step and [RuCl(H20)4(lm)]^2+ is themain solute in aqueous solution after the fourth hydrolysis step. | Hui Li Ting-Ting Sun Chao Zhang Linlin Liu Dongxia Zhao Zhongzhi Yang | 2017 | Chinese Journal of Chemistry2017，35，3： | 2 |
| 14 | Fabrication of high-quality all-graphene devices with low contact resistances显示文摘All-graphene 设备是有简单布局和低接触电阻的 graphene 设备的新班。这里,我们为 all-graphene 设备报导干净制造策略经由一帮助缺点的各向异性的蚀刻。同样制作的 graphene 没有污染并且保留太古的 graphene 的质量。在在一条 bilayer graphene 隧道和一个多层的 graphene 电极之间的房间温度(RT ) 的接触抵抗能象 5 | Rong Yang Shuang Wu Duoming Wang Guibai xie Meng Cheng Guole Wang Wei Yang Peng Chen Dongxia Shi Guangyu Zhang | 2014 | Nano Research2014，7，10： | 2 |
| 15 | Theory on the molecular characteristic contour (Ⅱ)——Molecular intrinsic characteristic contours of several typical organic molecules显示文摘The molecular intrinsic characteristic contour (MICC) is defined based on the clas-sical turning point of electron movement in a molecule. Three typical organic molecules, i.e. methane, methanol and formic acid, were employed as examples for detailed introduction of our method. Investigations on the cross-sections of MICC provide important information about atomic size changing in the process of forming molecules. The electron density distributions on the MICCs of these molecules were calculated and shown for the first time. Results showed that the electron density distribution on the MICC correlates closely with molecular chemical properties, and it provides a new insight into molecular boundary. | GONG Lidong ZHAO Dongxia YANG Zhongzhi | 2005 | Science China Chemistry2005，48，2： | 2 |
| 16 | Giant Valley Coherence at Room Temperature in 3R WS_(2) with Broken Inversion Symmetry显示文摘Breaking the space-time symmetries in materials can markedly influence their electronic and optical properties.In 3R-stacked transition metal dichalcogenides,the explicitly broken inversion symmetry enables valley-contrasting Berry curvature and quantization of electronic angular momentum,providing an unprecedented platform for valleytronics.Here,we study the valley coherence of 3R WS_(2) large single-crystal with thicknesses ranging from monolayer to octalayer at room temperature.Our measurements demonstrate that both A and B excitons possess robust and thickness-independent valley coherence.The valley coherence of direct A(B)excitons can reach 0.742(0.653)with excitation conditions on resonance with it.Such giant and thickness-independent valley coherence of large single-crystal 3R WS_(2) at room temperature would provide a firm foundation for quantum manipulation of the valley degree of freedom and practical application of valleytronics. | Luojun Du Jian Tang Jing Liang Mengzhou Liao Zhiyan Jia Qinghua Zhang Yanchong Zhao Rong Yang Dongxia Shi Lin Gu Jianyong Xiang Kaihui Liu Zhipei Sun Guangyu Zhang | 2019 | Research2019，，1： | 2 |
| 17 | Molecular dynamics study on BPTI aqueous solution by ABEEM/MM fluctuating charge model显示文摘Molecular dynamics simulation on BPTI (biovine pancreatic trypsin inhibitor) aqueous solution has been performed for the first time in terms of the atom-bond electronegativity equalization method fused with molecular mechanics (ABEEM/MM). The simulated parameters including ABEEM parameters and force field parameters have been tested. Some structural properties including root-mean-square deviations of atomic coordinates and radial distribution functions were studied by ABEEM/MM fluctuating charge method. The results demonstrate that this model can obtain reasonable structural properties compared with experimental crystal data. The radial distribution functions indicate that ABEEM/MM method can well embody the electrostatic polarizations between protein molecule and its surrounding solvent waters. | GUAN QingMei CUI BaoQiu ZHAO DongXia GONG LiDong YANG ZhongZhi | 2008 | Chinese Science Bulletin2008，53，8： | 2 |
| 18 | 1178 J,527 nm near diffraction limited laser based on a complete closed-loop adaptive optics controlled off-axis multi-pass amplification laser system显示文摘A 1178 J near diffraction limited 527 nm laser is realized in a complete closed-loop adaptive optics(AO)controlled off-axis multi-pass amplification laser system.Generated from a fiber laser and amplified by the pre-amplifier and the main amplifier,a 1053 nm laser beam with the energy of 1900 J is obtained and converted into a 527 nm laser beam by a KDP crystal with 62%conversion efficiency,1178 J and beam quality of 7.93 times the diffraction limit(DL).By using a complete closed-loop AO configuration,the static and dynamic wavefront distortions of the laser system are measured and compensated.After correction,the diameter of the circle enclosing 80%energy is improved remarkably from 7.93DL to 1.29DL.The focal spot is highly concentrated and the 1178 J,527 nm near diffraction limited laser is achieved. | Deen Wang Xin Zhang Wanjun Dai Ying Yang Xuewei Deng Lin Chen Xudong Xie Dongxia Hu Feng Jing Zeping Yang Qiang Yuan Xiaofeng Wei Qihua Zhu Wanguo Zheng Xiaomin Zhang Lei Huang | 2021 | High Power Laser Science and Engineering2021，9，2： | 1 |
| 19 | Molecular Hydrogels with Esterase-like Activity显示文摘能被申请的分子的 hydrogels 的开发 mimicking bioactive 分子在领域里吸引研究人员的广泛的兴趣自己组装。在这研究,我们基于酸肽的包含 L-histidine 由凉下来热的过程形成了的 naphthylacetic 在几分子的 hydrogels 上报导了。所有 hydrogels 比免费 L-histidine 展出了更高的活动到水解 4-nitrophenyl 醋酸盐(4-NPA ) 可能到期在自我装配的 nanofibers 的表面的 L-histidine 残余的高密度。为了计算 4-NPA 水解作用,评价, Michaelis-Menten 酶动力学模型被做。在这些胶化之中, Nap-GFFYGHY 的胶化拥有做酉旨契约劈开的最高的酶活动,它比控制(免费 L-histidine 和 Nap-GFFYGYY ) 的高约 25 倍。这些结果显示有自我装配的 nanofibers 的分子的 hydrogels 为自我装配的多价的材料的产生有大潜力。 | Chengbiao Yang Huaimin Wang Dongxia Li Ling Wang | 2013 | Chinese Journal of Chemistry2013，31，4： | 1 |
| 20 | Theory on the molecular characteristic contour (I)显示文摘 | Dongxia Zhao Zhongzhi Yang | 1999 | Science in China Series B: Chemistry1999，，4： | 1 |
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