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| 1 | Research Progress in the Use of Drugs for Breast Cancer Targeted Therapy显示文摘In recent years,many significant advances have been made on molecular target therapy to aim directly at epidermal growth factor receptors and vascular endothelial growth factor in breast cancers.Clinical studies of such agents as trastuzumab,lapatinib,erlotinib and bevacituzumab have been widely conducted.This paper will review the recent research progress related to targeted therapy. | Shun 'e Yang Bing Zhao | 2008 | Chinese Journal of Clinical Oncology2008，5，5： | 22 |
| 2 | YAP promotes osteogenesis and suppresses adipogenic differentiation by regulatingβ-catenin signaling显示文摘YAP(yes-associated protein) is a transcriptional factor that is negatively regulated by Hippo pathway, a conserved pathway for the development and size control of multiple organs. The exact function of YAP in bone homeostasis remains controversial. Here we provide evidence for YAP's function in promoting osteogenesis, suppressing adipogenesis, and thus maintaining bone homeostasis.YAP is selectively expressed in osteoblast(OB)-lineage cells. Conditionally knocking out Yap in the OB lineage in mice reduces cell proliferation and OB differentiation and increases adipocyte formation, resulting in a trabecular bone loss. Mechanistically, YAP interacts with β-catenin and is necessary for maintenance of nuclear β-catenin level and Wnt/β-catenin signaling. Expression of β-catenin in YAP-deficient BMSCs(bone marrow stromal cells) diminishes the osteogenesis deficit. These results thus identify YAP-β-catenin as an important pathway for osteogenesis during adult bone remodeling and uncover a mechanism underlying YAP regulation of bone homeostasis. | Jin-Xiu Pan Lei Xiong Kai Zhao Peng Zeng Bo Wang Fu-Lei Tang Dong Sun Hao-han Guo Xiao Yang Shun Cui Wen-Fang Xia Lin Mei Wen-Cheng Xiong | 2018 | Bone Research2018，6，2： | 19 |
| 3 | Altitudinal changes of surface pollen and vegetation on the north slope of the Middle Tianshan Mountains,China显示文摘To provide information on vegetation patterns and altitudinal distributions of pollen assemblage in surface soil layers,their complicated relationships in a dryland mountain-basin system in northwestern China and a realistic basis for paleovegetational reconstruction,we investigated 86 vegetation quadrats and analyzed 80 soil samples from the surface soil layers along an altitudinal transect on the north slope of the Middle Tianshan Mountains from alpine cushion vegetation at 3,510 m near glacier to desert vegetation at 460 m in the Gurbantunggut Desert.According to surface pollen assemblages and the results of the detrended correspondence analysis,the transect can be divided into six major altitudinal pollen zones as alpine cushion vegetation,alpine and subalpine meadows,montane Picea forest,forest-steppe ecotone,Artemisia desert and typical desert,which basically reflect the characteristics of the mountainous vegetation patterns on the north slope of the Middle Tianshan Mountains.However,Picea pollen also exists outside the spruce forest,Chenopodiaceae and Artemisia pollen appeared above the elevation of 1,300 m,indicating that most of them might be introduced from lower elevations by upslope winds.Airborne pollen researches from three regions at different elevations further suggest that a high-frequency northwest anabatic wind has a remarkable influence on the transportation and dispersion of surface pollen in the area. | YANG Zhenjing ZHANG Yun REN Haibao YAN Shun KONG Zhaochen MA Keping NI Jian | 2016 | Journal of Arid Land2016，8，5： | 17 |
| 4 | Calcium-binding ability of soy protein hydrolysates显示文摘This present study investigated the ability of various soy protein hydrolysates(SPHs)in binding calcium.It was demonstrated that the amount of Ca-bound depended greatly on the SPHs obtained using different proteases,which included:neutrase, flavourzyme,protease M and pepsin.The maximum level of Ca-bound(66.9 mg/g)occurred when protease M was used to hydrolyze soy protein.Peptide fragments exhibiting high Ca-binding capacity had molecular weights of either 14.4 or 8-9 kDa.The level of Ca-bound increased linearly with the increment of carboxyl content in SPHs,and further deamidation on SPHs from protease M improved Ca-binding of the hydrolysate. | Xiao Lan Bao Mei Song Jing Zhang Yang Chen Shun Tang Guo | 2007 | Chinese Chemical Letters2007，18，9： | 14 |
| 5 | MCP-1-induced ERK/GSK-3β/Snail signaling facilitates the epithelial-mesenchymal transition and promotes the migration of MCF-7 human breast carcinoma cells显示文摘Monocyte chemoattractant protein-1(MCP-1)is a chemotactic cytokine that can bind to its receptor cysteine-cysteine chemokine receptor 2(CCR2)and plays an important role in breast cancer cell metastasis.However,the molecular mechanisms underlying MCP-1-induced alterations in cellular functions during tumor progression are poorly understood.Here,we showed that MCP-1 stimulated the epithelial-mesenchymal transition(EMT)and induced the tumorigenesis of breast cancer cells by downregulating E-cadherin,upregulating vimentin and fibronectin,activating matrix metallopeptidase-2(MMP-2),and promoting migration and invasion.Moreover,MCP-1 treatment reduced glycogen synthase kinase-3β(GSK-3β)activity via the MEK/ERK-mediated phosphorylation of serine-9 in MCF-7 cells.The inhibition of MEK/ERK by U0126 attenuated the MCP-1-induced phosphorylation of GSK-3βand decreased the expression of Snail,an EMT-related transcription factor,leading to the inhibition of MCF-7 cell migration and invasion.Inactivation of GSK-3βby LiCl(lithium chloride)treatment notably increased MMP-2 activity,vascular endothelial growth factor expression and EMT of MCF-7 cells.These findings revealed that MCP-1-induced EMT and migration are mediated by the ERK/GSK-3β/Snail pathway,and identified a potential novel target for therapeutic intervention in breast cancer. | Shun Li Juan Lu Yu Chen Niya Xiong Li Li Jing Zhang Hong Yang Chunhui Wu Hongjuan Zeng Yiyao Liu | 2017 | Cellular & Molecular Immunology2017，14，7： | 14 |
| 6 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 7 | Sequential versus triple therapy for the first-line treatment of Helicobacter pylori : a multicentre, open-label, randomised trial显示文摘 | Jyh-Ming Liou Chieh-Chang Chen Mei-Jyh Chen Chien-Chuan Chen Chi-Yang Chang Yu-Jen Fang Ji–Yuh Lee Shih-Jer Hsu Jiing-Chyuan Luo Wen-Hsiung Chang Yao-Chun Hsu Cheng-Hao Tseng Ping-Huei Tseng Hsiu-Po Wang Ueng-Cheng Yang Chia-Tung Shun Jaw-Town Lin Yi-Chia | 2012 | The Lancet2012，，： | 13 |
| 8 | Association of Optic Radiation Integrity with Cortical Thickness in Children with Anisometropic Amblyopia显示文摘Previous studies have indicated regional abnormalities of both gray and white matter in amblyopia.However, alterations of cortical thickness associated with changes in white matter integrity have rarely been reported.In this study, structural magnetic resonance imaging and diffusion tensor imaging(DTI) data were obtained from 15 children with anisometropic amblyopia and 15 age- and gender-matched children with normal sight. Combining DTI and surface-based morphometry, we examined a potential linkage between disrupted white matter integrity and altered cortical thickness. The fractional anisotropy(FA) values in the optic radiations(ORs) of children with anisometropic amblyopia were lower than in controls(P \ 0.05). The cortical thickness in amblyopic children was lower than controls in the following subregions: lingual cortex, lateral occipitotemporal gyrus, cuneus, occipital lobe, inferior parietal lobe, and temporal lobe(P \ 0.05, corrected), but was higher in the calcarine gyrus(P \ 0.05, corrected). Node-by-node correlation analysis of changes in cortical thickness revealed a significant association between a lower FA value in the OR and diminished cortical thickness in the following subregions:medial lingual cortex, lateral occipitotemporal gyrus, lateral, superior, and medial occipital cortex, and lunate cortex. We also found a relationship between changes of cortical thickness and white matter OR integrity in amblyopia. These findings indicate that developmental changes occur simultaneously in the OR and visual cortex in amblyopia, and provide key information on complex damage of brain networks in anisometropic amblyopia. Our results also support the hypothesis that the pathogenesis of anisometropic amblyopia is neurodevelopmental. | Shun Qi Yun-Feng Mu Long-Biao Cui Rong Li Mei Shi Ying Liu Jun-Qing Xu Jian Zhang Jian Yang Hong Yin | 2016 | Neuroscience Bulletin2016，32，1： | 12 |
| 9 | Pollen record and environmental evolution of Caotanhu wetland in Xinjiang since 4550 cal. a BP显示文摘This paper presents a multi-proxy reconstruction of the climate change in Caotanhu wetland using pollen, phytolith and charcoal records, and the data of loss of ignition (LOI), grain size analysis, and susceptibility. Results reveal that between 4550 and 2500 cal. a BP, a dry climatic condition was not favorable for the accumulation of peat. Since 2500 cal. a BP, the climate became humid and the wetland developed with abundant freshwater aquatic plants, which contributed to peat accumulation. Never-theless, alternate periods of rain and dry climate occurred during that period. Between 2500 and 1810 cal. a BP (550 BC―140 AD), the climate was more humid than at present. A lot of emerged plants, such as Phragmites, Typha and Sparganium, and freshwater green algae grew in the wetland which was sur-rounded by desert-steppe vegetation composed mainly of Chenopodiaceae, Artemisia, Compositae and Thalictrum. However, from 1810 to 1160 cal. a BP (140―790 AD), the water level started to decrease and hydrophyte species reduced greatly, but some Phragmites still grew in the wetland and around it was desert vegetation with high proportion of Chenopodiaceae and Artemisia. Then from 1160 to 650 a BP (790―1300 AD), it entered a period of desert-steppe with abundant mesic and xerophytic plants. And a lot of aquatic plants prevailed in the wetland. Here, what is noticeable is that percentages of arboreal pollen, consisting mainly of Betula and Picea, increased greatly and reached a maximal value of 27.2%, in which, Betula percentages rose to 23.2%. Hence, it is reasonable to conclude that Betula grew in the highland of the wetland, or Picea timberline shifted downward resulting in the increase of percentages of Betula and Picea pollen, which were transported into the wetland by flood or wind. But since 650 cal. a BP, desert vegetation prevailed around the wetland again with dominant Chenopodiaceae and Ar-temisia, and the climate was similar to modern one. Despite some aquatic plants still growing in the wetland at that time, their amounts diminished greatly. | ZHANG Yun KONG ZhaoChen NI Jian YAN Shun YANG ZhenJing | 2008 | Chinese Science Bulletin2008，53，7： | 11 |
| 10 | An Abietane Diterpene and a Sterol from Fungus Phellinus igniarius显示文摘新 abietane diterpene12-hydroxy-7-oxo-5,8,11,13-tetraene-18,6-abietanolide 和新自然 sterolstigmasta-7,22-diene-3beta, 5alpha,6alpha-triol 从真菌 Phellinus igniarius.Their 结构的 fruiting 身体被孤立被分光镜的方法包括 2DNMR 技术阐明。 | Ying WANG Su Juan WANG Shun Yan MO Shuai LI Yong Chun YANG Jian Gong SHI | 2006 | Chinese Chemical Letters2006，17，4： | 10 |
| 11 | Fluctuation of Picea timberline and paleoenvironment onthe northern slope of Tian-shan Mountains during the late Holocene显示文摘As a good indicator of Holocene climate, the fluctuation of alpine timberline is a synthetical result of impacts of many environmental factors dur-ing geological and historical periods and modern times. As the dominant tree species of mountainous conifer forests on the northern slope of Tianshan Mountains in Xinjiang, the distribution of Picea schrenkiana and its population size are sensitive to climatic change. The typical natural profile of Huashuwozi and the nearby Xiaoxigou archaeologi-cal profile, located in Quanzijie Township, Jimusaer County in Xinjiang, were chosen to analyze and compare the relative high-resolution pollen records, and to measure 14C dating and SEM (scanning elec-tron microscope) microstructure for charcoal frag-ments contained in Xiaoxigou profile’s cultural layers. The results show that in these two profiles, the high percentages of Picea (more than 20% and 35%, re-spectively) appeared in the stratum of the same pe-riod (2000-1300 a BP), which corresponds to the charcoal fragment’s age of Picea schrenkiana con-tained in Xiaoxigou cultural layers. These results convincingly revealed that during the period of 2000-1300 a BP, the timberline for Picea schrenkiana on the northern slope of Tianshan Mountains in Xinjiang declined by about 330m compared with the present. | ZHANG Yun KONG Zhaochen YAN Shun YANG Zhenjing NI Jian | 2006 | Chinese Science Bulletin2006，51，14： | 9 |
| 12 | The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population显示文摘导致噪音的听觉损失(NIHL ) 是在环境、基因的因素之间的相互作用引起的复杂疾病。这研究调查了在 protocadherin 的基因可变性是否联系了 15 (PCDH15 ) 在一张中国人口位于增加的危险性下面到 NIHL 的发展。结果证明与 rs11004085 的 TT 遗传型相比, CT/CC 遗传型与 NIHL 的增加的风险被联系[调整机会比率(或)= 2.64;95% 信心间隔(CI ) :1.14-6.11, P = 0.024 ] 。另外,在 rs11004085 和 rs978842 之间的重要相互作用基因变化和噪音暴露在高级暴露组被观察(P < 0.05 ) 。而且,当与噪音暴露的高水平结合了时,风险 haplotype TAGCC 被观察(P < 0.05 ) 。因此,我们的学习证实在 PCDH15 的基因变化在人修改危险性到 NIHL 开发。 | XU Xiang Rong WANG Jing Jing YANG Qiu Yue JIAO Jie HE Li Hua YU Shan Fa GU Gui Zhen CHEN Guo Shun ZHOU Wen Hui WU Hui LI Yan Hong ZHANG Huan Ling ZHANG Zeng Rui JIN Xian Ning | 2017 | Biomedical and Environmental Sciences2017，30，2： | 9 |
| 13 | Disinfection byproducts in drinking water and regulatory compliance: A critical review显示文摘消毒副产品(DBP ) 在在很多个国家喝水被调整。这批评评论集中于与 DBP 规章的依从联系的问题,包括为 DBP 分析,出现层次,在各种各样的国家之中的规定比较, DBP 依从策略,和新兴的 DBP 的方法。在中国和美国(美国) 之间的规定比较显示在中国的 DBP 规定基于调整混合物和最大的层次的数字是更紧的。用信息收集规则(ICR ) 数据库的比较评价显示 500 大美国的依从率在中国规定下面浇植物在 US 规定下面是比那低得多的(例如 62.2% 对 89.6% 为全部的 trihalomethanes ) 。先锋移动和其他的 disinfectants 是为 DBP 规章的依从的普通惯例。包括为 haloacetic 酸移动为 trihalomethane 移动和 biodegradation 脱衣的空气,在形成以后的 DBP 移动在 DBP 控制获得了更多的接受。包括 iodinated DBP 和含氮的 DBP,新兴的 DBP 的形成是先锋移动和其他的消毒的非计划中的后果之一。然而,在许多底层,比碳的 DBP,新兴的 DBP 提出了更高的健康风险。 | Xiaomao WANG Yuqin MAO Shun TANG Hongwei YANG Yuefeng E XIE | 2015 | Frontiers of Environmental Science & Engineering2015，9，1： | 8 |
| 14 | Effectiveness of PD-1/PD-L1 inhibitors in the treatment of lung cancer:Brightness and challenge显示文摘Immune checkpoint inhibitors(ICIs),especially inhibitors of the PD-1/PD-L1 axis,have significantly affected the outcomes of patients with lung cancer.Nivolumab and pembrolizumab have been approved as PD-1 blocking antibodies,whereas atezolizumab,avelumab,and durvalumab are approved as PD-L1 blocking antibodies by the United States Food and Drug Administration.However,which patient may benefit the most and how to identify patients at risk of primary or acquired resistance has not been completely defined.Meanwhile,close attention has been paid to the ongoing international and domestic clinical trials in Chinese patients with lung cancer.This review aimed to provide deep insight into the effectiveness of PD-1/PD-L1 inhibitors in patients with lung cancer,including the current settings for varied disease status,the predictive biomarkers,the resistance to ICIs,and the ongoing clinical trials in Chinese patients. | Ying Yang Yongfeng Yu Shun Lu | 2020 | Science China(Life Sciences)2020，63，10： | 8 |
| 15 | Peripheral CD4^(+) T cell signatures in predicting the responses to anti-PD-1/PD-L1 monotherapy for Chinese advanced non-small cell lung cancer显示文摘Limited benefit population of immune checkpoint inhibitors makes it urgent to screen predictive biomarkers for stratifying the patients.Herein,we have investigated peripheral CD4^(+) T cell signatures in advanced non-small cell lung cancer(NSCLC)patients receiving anti-PD-1/PD-L1 treatments.It was found that the percentages of IFN-γand IL-17A secreting naïve CD4^(+) T cells(Tn),and memory CD4^(+) T cells(Tm)expressing PD-1,PD-L1 and CTLA-4 were significantly higher in responder(R)than non-responder(NonR)NSCLC patients associated with a longer progression free survival(PFS).Logistic regression analysis revealed that the baseline IFN-γ-producing CD4^(+) Tn cells and PD-1^(+)CD4^(+) Tm cells were the most significant signatures with the area under curve(AUC)value reaching 0.849.This was further validated in another anti-PD-1 monotherapy cohort.Conversely,high percentage of CTLA-4^(+)CD4^(+) Tm cells was associated with a shorter PFS in patients receiving anti-PD-L1 monotherapy.Our study therefore elucidates the significance of functional CD4^(+) Tn and Tm subpopulations before the treatment in predicting the responses to anti-PD-1 treatment in Chinese NSCLC patients.The fact that there display distinct CD4^(+) T cell signatures in the prediction to anti-PD-1 and anti-PD-L1 monotherapy from our study provides preliminary evidence on the feasibility of anti-PD-1 and anti-PD-L1 combination therapy for advanced NSCLC patients. | Liliang Xia Hui Wang Mingjiao Sun Yi Yang Chengcheng Yao Sheng He Huangqi Duan Weimin Xia Ruiming Sun Yaxian Yao Zhiwei Chen Qiong Zhao Hong Li Shun Lu Ying Wang | 2021 | Science China(Life Sciences)2021，64，10： | 7 |
| 16 | Intradural spinal seeding and fatal progression of a sacrococcygeal chordoma: a case report显示文摘 | JI Tao GUO Wei SHEN Dan-hua YANG Yi TANG Shun | 2008 | Chinese Medical Journal2008，，12： | 7 |
| 17 | Fast-track surgery in elderly patients undergoing colorectal cancer radical resection显示文摘Purpose:To investigate the efficacy of applying fast-track surgery(FTS)to elderly patients undergoing radical resection of colorectal cancer.Methods:Elderly patients undergoing radical resection of colorectal cancer received FTS(n=31)or routine(n=31)nursing care.The time to first anal exhaust,oral feeding and leaving the bed,duration of postoperative hospital stay and the incidence of complications were compared between the two groups.Results:Patients receiving FTS nursing demonstrated significantly shorter times to exhaust,oral feeding and leaving the bed compared with those receiving routine nursing(all p<0.01).Furthermore,there were significantly fewer incidences of postoperative pulmonary and urinary tract infections and intestinal adhesion in patients receiving FTS nursing(all p<0.05).Conclusion:Application of FTS in elderly patients undergoing radical resection of colorectal cancer facilitates an early rehabilitation after surgery,but places higher demands on nursing care. | Hong-Yan Kong Ai-Ling Yang Cai-Ya Ying Zhen-Fang Kong Ling-Ling Yuan Shan-Shan Hu Shun Zhang | 2014 | International Journal of Nursing Sciences2014，1，4： | 6 |
| 18 | Extractive distillation: Advances in conceptual design, solvent selection,and separation strategies显示文摘Extractive distillation(ED) is one of the most promising approaches for the separation of the azeotropic or closeboiling mixtures in the chemical industry. The purpose of this paper is to provide a broad overview of the recent development of key aspects in the ED process involving conceptual design, solvent selection, and separation strategies. To obtain the minimum entrainer feed flow rate and reflux ratio for the ED process, the conceptual design of azeotropic mixture separation based on a topological analysis via thermodynamic feasibility insights involving residue curve maps, univolatility lines, and unidistribution curves is presented. The method is applicable to arbitrary multicomponent mixtures and allows direct screening of design alternatives. The determination of a suitable solvent is one of the key steps to ensure an effective and economical ED process. Candidate entrainers can be obtained from heuristics or literature studies while computer aided molecular design(CAMD) has superiority in efficiency and reliability. To achieve optimized extractive distillation systems, a brief review of evaluation method for both entrainer design and selection through CAMD is presented. Extractive distillation can be operated either in continuous extractive distillation(CED) or batch extractive distillation(BED), and both modes have been well-studied depending on the advantages in flexibility and low capital costs. To improve the energy efficiency, several configurations and technological alternatives can be used for both CED and BED depending on strategies and main azeotropic feeds. The challenge and chance of the further ED development involving screening the best potential solvents and exploring the energy-intensive separation strategies are discussed aiming at promoting the industrial application of this environmentally friendly separation technique. | Shirui Sun Liping Lü Ao Yang Shun'an Wei Weifeng Shen | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 6 |
| 19 | Two Pyrone Derivatives from Fungus Phellinus Igniarius显示文摘Two new pyrone derivatives phelligridins A 1 and B 2 were isolated from the fruit body of Phellinus igniarius. Their structrues were elucidated as 8, 9-dihydroxy-3-methyl-1H,6H- pyrano[4,3-c][2]benzopyran-1,6-dione and 4-hydroxy-6-(3,4-dihydroxystyryl)-3-methoxycarbon- yl-2-pyrone , respectively, by means of spectral methods, including IR, MS, 1D and 2DNMR spectra. | Shun Yan MO, Yong Chun YANG, Wen Yi He, Jian Gong SHI* Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050 | 2003 | Chinese Chemical Letters2003，14，7： | 6 |
| 20 | Room temperature ferromagnetism in ultra-thin van der Waals crystals of 1T-CrTe2显示文摘Although many emerging new phenomena have been unraveled in two dimensional(2D)materials with long-range spin orderings,the usually low critical temperature in van der Waals(vdW)magnetic material has thus far hindered the related practical applications.Here,we show that ferromagnetism can hold above 300 K in a metallic phase of 1T-CrTe2 down to the ultra-thin limit.It thus makes CrTe2 so far the only known exfoliated ultra-thin vdW magnets with intrinsic long-range magnetic ordering above room temperature.An in-plane room-temperature negative anisotropic magnetoresistance(AMR)was obtained in ultra-thin CrTe2 devices,with a sign change in the AMR at lower temperature,with−0.6%and+5%at 300 and 10 K,respectively.Our findings provide insights into magnetism in ultra-thin CrTe2,expanding the vdW crystals toolbox for future room-temperature spintronic applications. | Xingdan Sun Wanying Li Xiao Wang Qi Sui Tongyao Zhang Zhi Wang Long Liu Da Li Shun Feng Siyu Zhong Hanwen Wang Vincent Bouchiat Manuel Nunez Regueiro Nicolas Rougemaille Johann Coraux Anike Purbawati Abdellali Hadj-Azzem Zhenhua Wang Baojuan Dong Xing Wu Teng Yang Guoqiang Yu Bingwu Wang Zheng Han Xiufeng Han Zhidong Zhang | 2020 | Nano Research2020，13，12： | 6 |
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