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| 1 | Genome-wide Scan for Seed Composition Provides Insights into Soybean Quality Improvement and the Impacts of Domestication and Breeding显示文摘优秀特点的复杂基因建筑学妨碍了努力在大豆修改种子营养素。染色体宽的协会研究为种子作文被进行,包括蛋白质,油,丰满的酸,和氨基酸,用有一个高密度的 SNP 数组的 313 多样的大豆 germplasm 就职 genotyped。87 个 chromosomal 区域的一个总数被识别与种子作文被联系,解释基因变化的 8%-89% 。已知的功能的候选人基因 GmSAT1, AK-HSDH, SACPD-C,和 FAD3A,和通常认为的 MtN21 nodulin, FATB,和 steroid-5 -- 涉及 N 2 固定,氨基酸生合成,和丰满的酸新陈代谢的 reductase 在主要效果的 loci 被发现。另外的 germplasm 就职的进一步的分析显示这些主要效果的 loci 受到了驯服或现代繁殖选择,并且突变而产生之遗传的变体和分布与地理区域相关。我们也表明与种子重量有关并且到全部的蛋白质的氨基酸集中有一个不同基因基础。这帮助揭开在种子之中的复杂关系的深入的基因机制加重。因此,我们的学习不仅为大豆营养素改进提供珍贵基因和标记,份量上和品质上,而且进在驯服期间优秀、引起的大豆的改变的提议卓见。 | Jiaoping Zhang Xianzhi Wang Yaming Lu Siddhi J. Bhusal Qijian Song Perry B. Cregan Yang Yen Michael Brown Guo-Liang Jiang | 2018 | Molecular Plant2018，11，3： | 12 |
| 2 | Synthesizing double haploid hexaploid wheat populations based on a spontaneous alloploidization process显示文摘加倍的 haploid (DH ) 人口在庄稼改进和基本研究对科学家和 breeders 有用。生产 DH 的当前的方法通常为为染色体加倍提取 haploids 和化学处理在 vitro 需要文化。这份报告为综合描述一个简单方法特别为由利用 meiotic 归还基因的 allopolyploid 种类的 DH (SynDH ) 。方法包含三个步骤:杂交将导致再结合,提取 haploids 的种间的杂交,和由 selfing 加倍种间的 F1s 的自发的染色体。这样生产的 DH 在对一个同类的背景的兴趣的染色体包含 recombinant 染色体。没有特殊设备或处理涉及 DH 生产,它能容易在任何繁殖或基因节目被使用。Triticum turgidum L。并且 Aegilops tauschii Coss,普通小麦(Triticum aestivum L.) 的二祖先的种和分子的标记被用来表明 SynDH 方法。 | Lianquan Zhang Li Zhang Jiangtao Luo Wenjie Chen Ming Hao Baolong Liu Zehong Yan Bo Zhang Huaigang Zhang Youliang Zheng Dengcai Liu Yang Yen | 2011 | Journal of Genetics and Genomics2011，38，2： | 5 |
| 3 | Occurrence, spatial distribution and ecological risks of antibiotics in soil in urban agglomeration显示文摘Antibiotics in soil environment are regarded as emerging pollutants and have introduced increasing risks to soil ecosystem and human health in rapid urbanization areas. Identifying the occurrence and spatial variability of antibiotics in soils is an urgent issue in sustaining soil security. In this study, antibiotics in soils were investigated and analyzed in BeijingTianjin-Hebei urban agglomeration. The occurrence, spatial distribution, and related affecting factors of antibiotics in soils were identified and ecological risks of antibiotics in soil environment were assessed. Results showed that(1) The mean concentration of soil antibiotics in Beijing-Tianjin-Hebei urban agglomeration was 21.79 μg/kg. Land use substantially affected the occurrence and concentration of antibiotics in soils. Concentrations of antibiotics in cropland and orchard soils were 2-3 times higher than the other land use types.(2)The concentrations of antibiotics in soils in Beijing-Tianjin-Hebei urban agglomeration presented a spatial pattern of high values in southeast, and low values in northwest. Spatial variability of antibiotics in soils was closely related to the application of organic fertilizer and wastewater irrigation as well as topographical features. Furthermore, soil properties and land management policy had substantial influences on soil antibiotics, and soil heavy metals may aggravate the accumulation of antibiotics in soils.(3) Ecological risks assessment of antibiotics in soils demonstrated that erythromycin(ERY), sulfamethoxazole(SMX), and doxycycline(DOX) may introduce high risks to soil ecosystem health, and more attention should be paid to the areas with intensive human activities that had potential high risk to soil ecosystem health. This study suggests that scientific land and soil management should be considered to prevent soil antibiotic pollution and sustain soil security in urban agglomeration. | Min Li Lei Yang Haw Yen Fangkai Zhao Xinmiao Wang Tianhui Zhou Qingyu Feng Liding Chen | 2023 | Journal of Environmental Sciences2023，，3： | 5 |
| 4 | Clinical impact of multidetector computed tomography before double-balloon enteroscopy for obscure gastrointestinal bleeding显示文摘AIM:To evaluate the clinical impact of multidetector computed tomography (MDCT) before double-balloon endoscopy (DBE) for patients with obscure gastrointestinal bleeding (OGIB).METHODS:A retrospective analysis of prospectively collected cases with DBE and MDCT for overt OGIB was conducted from April 2004 to April 2010 at Changhua Christian Hospital.We evaluated the clinical impact of MDCT on the subsequent DBE examinations and the diagnostic yields of both MDCT and DBE respectively.RESULTS:From April 2004 to April 2010,a total of 75 patients underwent DBE for overt OGIB.Thirty one cases received MDCT followed by DBE for OGIB.The overall diagnostic yields of DBE and MDCT was 93.5% and 45.2%.The MDCT had a high diagnostic yield of tumor vs non-tumor etiology of OGIB (85.7% vs 33.3%,P=0.014).Additionally,the choice of initial route of DBE was correct in those with a positive MDCT vs negative MDCT (100% vs 52.9%,P=0.003).CONCLUSION:This study suggests MDCT as a triage tool may identify patients who will benefit from DBE and aid the endoscopist in choosing the most efficient route. | Hsu-Heng Yen Yang-Yuan Chen Chia-Wei Yang Chi-Kuang Liu Maw-Soan Soon | 2012 | World Journal of Gastroenterology2012，18，7： | 5 |
| 5 | Synopsis of Leymus Hochst.(Triticeae:Poaceae)显示文摘Leymus is a genus in the Triticeae tribe, Poaceae. The taxa of this genus are allopolyploid species which possess the Ns and Xm genomes. According to cytological, cytogenetic and molecular genetic analyses, some species of Hystrix and Elymus ought to be transferred to this genus. A world revision of the genus Leymus is needed. In this paper we summarize experimental results, provide a key to sections, species and varieties, and list all the taxa we recognize in Leymus with their synonyms. This synopsis is a new taxonomic system to be used for the revision of Leymus. | Chi YEN Jun-Liang YANG Bernard R. BAUM | 2009 | Journal of Systematics and Evolution2009，47，1： | 4 |
| 6 | A taxonomic synopsis of the genus Campeiostachys Drobov显示文摘We have classified 11 species recently recognized as belonging to the genus Elymus into a resurrected and legitimate genus Campeiostachys Drobov according to the International Code of Botanical Nomenclature. Our action is based on the rationale of monophyly, discrimination, and practicality discussed in detail. Currently Elymus contains a vast number of species with different genomes which often, but not always, can be differentiated by cytological and molecular features, but are difficult to separate by traditional morphology, although an effort to do so is detailed and discussed. This difficulty can be attributed to the dominance effect of a particular genome on the other genome(s) present. Campeiostachys, with genome constitution StStHHYY, is a recent addition to a number of genera recently segregated out of Elymus, i.e. Douglasdeweya (StStPP), Kengyilia (StStPPYY), and Roegneria (StStYY, StStStStYY). A key to Campeiostachys taxa is provided, along with taxa descriptions, distribution, nomenclature, and cytology. Nineteen nomenclatural novelties, or combinations, resulted from this work, 10 species names, and nine varietal names. | Bemard R. BAUM jun-Liang YANG Chi YEN Alex V AGAFONOV | 2011 | Journal of Systematics and Evolution2011，49，2： | 3 |
| 7 | Control of T H 17/T reg Balance by Hypoxia-Inducible Factor 1显示文摘 | Eric V. Dang Joseph Barbi Huang-Yu Yang Dilini Jinasena Hong Yu Ying Zheng Zachary Bordman Juan Fu Young Kim Hung-Rong Yen Weibo Luo Karen Zeller Larissa Shimoda Suzanne L. Topalian Gregg L. Semenza Chi V. Dang Drew M. Pardoll Fan Pan | 2011 | Cell2011，，5： | 3 |
| 8 | Five-year sequential changes in secondary antibiotic resistance of Helicobacter pylori in Taiwan显示文摘AIM: To determine changes in the antibiotic resistance of Helicobacter pylori(H. pylori) in southern Taiwan after failure of first-line standard triple therapy.METHODS: We analyzed 137 H. pylori-infected isolates from patients who experienced eradication failure after standard first-line triple therapy from January2010 to December 2014. The H. pylori strains were tested for susceptibility to amoxicillin, clarithromycin,levofloxacin, metronidazole and tetracycline using the E-test method. The minimal inhibitory concentration(MIC) was determined by the agar dilution test.MIC values of ≥ 0.5, ≥ 1, ≥ 1, ≥ 4 and ≥ 8 mg/L were considered to be the resistance breakpoints for amoxicillin, clarithromycin, levofloxacin, tetracycline and metronidazole, respectively.RESULTS: A high resistance rate was found for clarithromycin(65%-75%) and metronidazole(30%-40%)among patients who failed first-line standard therapy.The resistance levels to amoxicillin and tetracycline remained very low; however, levofloxacin resistance was as high as 37.5% in 2010 but did not increase any further during the past 5 years. The rates of resistance to these antibiotics did not show a statistically significant upward or downward trend.CONCLUSION: Antibiotic resistance of H. pylori remains a problem for the effective eradication of this pathogen and its associated diseases in Taiwan. High clarithromycin resistance indicated that this antibiotic should not be prescribed as a second-line H. pylori eradication therapy. Moreover, levofloxacin-based second-line therapy should be used cautiously, and the local resistance rates should be carefully monitored. | I-Ting Wu Seng-Kee Chuah Chen-Hsiang Lee Chih-Ming Liang Lung-Sheng Lu Yuan-Hung Kuo Yi-Hao Yen Ming-Luen Hu Yeh-Pin Chou Shih-Cheng Yang Chung-Mou Kuo Chung-Huang Kuo Chun-Chih Chien Yu-Shao Chiang Shue-Shian Chiou Tsung-Hui Hu Wei-Chen Tai | 2015 | World Journal of Gastroenterology2015，21，37： | 3 |
| 9 | Adult metaplastic hutch diverticulum with robotic-assisted diverticulectomy and reconstruction:A case report显示文摘BACKGROUND Hutch diverticulum arises from the compromised muscular development at the ureteral orifice.It is a congenital disease and extremely rare in adult,only accounting for about 3%occurrence worldwide.It can be either symptomatic or asymptomatic,and relies on image tools for diagnosis and preoperative planning.Indications for surgery are dependent on the complications from the diverticulum.Metaplasia is about 10%among those with hutch diverticulum,and it still has chances turning into malignancy,especially urothelial cell carcinoma.CASE SUMMARY A 27-year-old man was presented with frequently recurrent urinary tract infection for one year,and had suffered from intermittent right flank pain for 3 mo.No past medical histories were recorded before.No obvious abnormalities on laboratory data and urine examination were found.Under ultrasound,right hydronephrosis was seen and an anatomical abnormality was observed on intravenous pyelography.Further computed tomography urogram showed one diverticulum seated at superolateral side of right ureteral orifice.Cystoscopy was done and biopsy results showed focal metaplasia.After discussing with him,roboticassisted diverticulectomy with reconstruction was performed.Right hydronephrosis was greatly improved after surgery.He has completed his 1.5-year follow-ups,and no malignancies were seen from urine cytology and image of intravenous pyelography.CONCLUSION Robotic-assisted diverticulectomy and reconstruction to hutch diverticulum is a safe and efficient operation,providing several advantages over open and laparoscopic ones. | Che H Yang Yi S Lin Yen C Ou Wei C Weng Li H Huang Chin H Lu Chao Y Hsu Min C Tung | 2020 | World Journal of Clinical Cases2020，8，20： | 2 |
| 10 | Effects of Maternal Screening and Universal Immunization to Prevent Mother-to-Infant Transmission of HBV显示文摘 | Huey–Ling Chen Lung–Huang Lin Fu–Chang Hu Jian–Te Lee Wen–Terng Lin Yao–Jung Yang Fu–Chen Huang Shu–Fen Wu Solomon Chih–Cheng Chen Wan–Hsin Wen Chia–Hsiang Chu Yen–Hsuan Ni Hong–Yuan Hsu Pei–Lin Tsai Cheng–Lun Chiang Ming–Kwang Shyu Ping–Ing Lee Feng–Yee | 2012 | Gastroenterology2012，，4： | 2 |
| 11 | Roegneria: its generic limits and justification for its recognition显示文摘 | Baum B R Yen J Yang J L | 1991 | Canadian Journal of Bota- ny1991，69，： | 1 |
| 12 | Early identification of lepto- spirosis as an ignored cause of muhiple organ dysfunction syndrome 显示文摘 | Yang HY Yen TH Lin CY | 2012 | Shock2012，38，1： | 1 |
| 13 | Efficient Green Coumarin Dopants for Organic Light-Emitting Devices显示文摘 | Lee M T Yen C K Yang W P | 2004 | Org Lett2004，6，： | 1 |
| 14 | Antioxidant properties of chitosan from crab shells显示文摘 | Yen M T Yang J H Mau J L | 2008 | Carbohydrate Polymers2008，74，4： | 1 |
| 15 | Optically tuned resonant optical reflectance filter显示文摘 | YANG F YEN G RASIGADE G | 2008 | Applied Physics Letters2008，92，9： | 1 |
| 16 | The osteopontin CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/ Akt Signaling Pathway显示文摘 | Lin Y H Yang Yen H F | 2001 | J Biol Chem2001，276，46： | 1 |
| 17 | Curcumin induced apoptosis in immortalized NIH3T3 and malignant cancer cell lines 显示文摘 | Jiang MC Yang Yen HF Yen JJ | 1996 | Biochim Biophys Acta1996，26，1： | 1 |
| 18 | Salvinal, a Novel Mierotubule Inhibitor Isolated from Salvia miltiorrhizae Bunge (Danshen), with Antimitotie Activity in Multidrug- Sensitive and -Resistant Human Tumor Cells显示文摘 | JANG -YANG CHANG CHI YEN CHANG CHING -CHUAN KUO | 2004 | Mol Pharmaeol2004，65，： | 1 |
| 19 | The Feasibility of Total or Near-Total Bilateral Thyroidectomy for the Treatment of Bilateral Multinodular Goiter显示文摘 | Weiping Yang Tanglei Shao Jiazeng Ding Xiaotai Jin Qinyu Li Peiguo G. Chu Yun Yen Weihua Qiu | 2009 | Investigative Surgery2009，，3： | 1 |
| 20 | Direct cholangioscopy using an uhrathin endoscope for the diagnosis of hemobilia 显示文摘 | Yen HH Yang CW Chen YY | 2014 | Dig Endosc2014，26，3： | 1 |
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