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| 1 | Correcting method of eddy covariance fluxes over non-flat surfaces and its application in ChinaFLUX显示文摘Although Eddy Covariance (EC) technique is one of the best methods for estimating the energy and mass exchanges between underlying surface and atmosphere in micrometeorology, errors and uncertainties still exist without necessary corrections. In this paper, we will focus on the effect of coordinate system on the eddy fluxes. Based on the data observed over four sites (one farmland site, one grassland site and two forest sites), the effects of three coordinate system transforming methods (Double Rotation-DR, Triple Rotation-TR and Planar Fit-PF)on the turbulent fluxes are analyzed. It shows that (i) the corrected fluxes are more or less than the uncorrected fluxes, which is related mainly to the sloping degree of surface, wind speed and wind direction; and (ii) pitch angle has a sinusoidal dependence on wind direction, especially in the regular sloping terrain; and (iii) PF method is something like the simplification of TR or DR,and there are not obvious distinctions in correction in sloping grassland and flat farmland, but PF method is not suitable for uneven and irregular forest sites. | ZHU Zhilin, SUN Xiaomin, ZHOU Yanlian, XU Jinping, YUAN Guofu & ZHANG Renhua Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China Graduate School of the Chinese Academy of Sciences, Beijing 100039, China | 2005 | Science China Earth Sciences2005，48，z1： | 10 |
| 2 | Influence of DCM dye doping on the magnetic field dependent electroluminescence in organic light emitting diodes显示文摘The DCM dye doped organic electroluminescence devices with structure of ITO/NPB/Alq 3 : DCM/Alq 3 /LiF/Al were fabricated. From 15 K to room temperature, the magnetic field dependent of electroluminescence (MEL) of devices was investigated. Our observations indicated that the MEL is composed of two effects in different regimes: a low field (0≤B≤40 mT) effect and a high field (B > 40 mT) effect. For undoped devices, the low field effect exhibits a rapid rising with the increasing field, and the high field effect shows a slow increase and gradually saturates at room temperature. For doped devices, the low field rapid increase is also present, whereas the high field effect displays a decrease with the increasing field. The larger the injection current is, the more apparent the high field decrease is. In addition, the doped device demonstrates less temperature dependence of the high field effect than undoped device, although the undoped devices also present high field decrease of electroluminescence at low temperatures (T≤150 K). Based on the energy level trapping effect due to dye doping and magnetic field modulated triplet exciton annihilation, the experimental results are carefully explained. | CHEN Ping, LEI YanLian, LIU Rong, ZHANG QiaoMing, ZHANG Yong & XIONG ZuHong School of Physical Science and Technology, MOE Key Laboratory on Luminescence and Real-Time Analysis, Southwest University, Chongqing 400715, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，1： | 10 |
| 3 | Engineering Ruthenium-Based Electrocatalysts for Effective Hydrogen Evolution Reaction显示文摘The investigation of highly effective,durable,and cost-effective electrocatalysts for the hydrogen evolution reaction(HER)is a prerequisite for the upcoming hydrogen energy society.To establish a new hydrogen energy system and gradually replace the traditional fossil-based energy,electrochemical water-splitting is considered the most promising,environmentally friendly,and efficient way to produce pure hydrogen.Compared with the commonly used platinum(Pt)-based catalysts,ruthenium(Ru)is expected to be a good alternative because of its similar hydrogen bonding energy,lower water decomposition barrier,and considerably lower price.Analyzing and revealing the HER mechanisms,as well as identifying a rational design of Ru-based HER catalysts with desirable activity and stability is indispensable.In this review,the research progress on HER electrocatalysts and the relevant describing parameters for HER performance are briefly introduced.Moreover,four major strategies to improve the performance of Ru-based electrocatalysts,including electronic effect modulation,support engineering,structure design,and maximum utilization(single atom)are discussed.Finally,the challenges,solutions and prospects are highlighted to prompt the practical applications of Rubased electrocatalysts for HER. | Yingjie Yang Yanhui Yu Jing Li Qingrong Chen Yanlian Du Peng Rao Ruisong Li Chunman Jia Zhenye Kang Peilin Deng Yijun Shen Xinlong Tian | 2021 | Nano-Micro Letters2021，13，10： | 5 |
| 4 | Combined peripheral natural killer cell and circulating tumor cell enumeration enhance prognostic efficiency in patients with metastatic triple-negative breast cancer显示文摘Objective:Triple-negative breast cancer(TNBC)is a heterogeneous disease with poor prognosis.Circulating tumor cells(CTCs)are a promising predictor for breast cancer prognoses but their reliability regarding progression-free survival(PFS)is controversial.We aim to verify their predictive value in TNBC.Methods:In present prospective cohort study,we used the Pep@MNPs method to enumerate CTCs in baseline blood samples from 75 patients with TNBC(taken at inclusion in this study)and analyzed correlations between CTC numbers and outcomes and other clinical parameters.Results:Median PFS was 6.0(range:1.0–25.0)months for the entire cohort,in whom we found no correlations between baseline CTC status and initial tumor stage(P=0.167),tumor grade(P=0.783)or histological type(P=0.084).However,among those getting first-line treatment,baseline CTC status was positively correlated with ratio of peripheral natural killer(NK)cells(P=0.032),presence of lung metastasis(P=0.034)and number of visceral metastatic site(P=0.037).Baseline CTC status was predictive for PFS in first-line TNBC(P=0.033),but not for the cohort as a whole(P=0.118).This prognostic limitation of CTC could be ameliorated by combining CTC and NK cell enumeration(P=0.049).Conclusions:Baseline CTC status was predictive of lung metastasis,peripheral NK cell ratio and PFS in TNBC patients undergoing first-line treatment.We have developed a combined CTC-NK enumeration strategy that allows us to predict PFS in TNBC without any preconditions. | Xiaoran Liu Ran Ran Bin Shao Hope S.Rugo Yanlian Yang Zhiyuan Hu Zewen Wei Fengling Wan Weiyao Kong Guohong Song Hanfang Jiang Xu Liang Ruyan Zhang Ying Yan Guobing Xu Huiping Li | 2018 | Chinese Journal of Cancer Research2018，30，3： | 4 |
| 5 | Determination of averaging period parameter and its effects analysis for eddy covariance measurements显示文摘It is more and more popular to estimate the exchange of water vapor, heat and CO2fluxes between the land surface and the atmosphere using the eddy covariance technique. To get believable fluxes, it is necessary to correct the observations based on the different surface conditions and to determine relevant techinical parameters. The raw 10 Hz eddy covariance data observed in the Yucheng and Changbai Mountains stations were recalculated by various averaging periods (from 1 to 720 min) respectively, and the recalculated results were compared with the results calculated by the averaging period of 30 mins. Meanwhile, the distinctions of fluxes calculated by different averaging periods were analyzed. The continuous 15 days observations over wheat fields in the Yucheng station were mainly analyzed. The results are shown that: (i) In the Yucheng station, compared with the observations by 30 min, when the averaging period changes from 10 to 60 min, the variations of the eddy-covariance estimates of fluxes were less than 2%; when the averaging period changes less than 10 min, the estimate of fluxes reduced obviously with the reduction of the averaging period (the max relative error was -12%); and when the averaging period exceeds 120 min, the eddy covariance estimates of fluxes will be increased and become unsteady (the max relative error is over 10%); (ii) the eddy covariance estimates of fluxes over wheat field in the Yucheng station suggusted that it is much better to take 10 min as an averaging period in studying diurnal change of fluxes, and take 30min for a long-term flux observation; and (iii) normalized ratio was put forward to determine the range of averaging period of eddy covariance measurements. By comparing the observations over farmlands and those over forests, it is indicated that the increase of eddy covariance estimates over tall forest was more than that over short vegetation when the averaging period increased. | SUN Xiaomin, ZHU Zhilin, XU Jinping, YUAN Guofu , ZHOU Yanlian & ZHANG Renhua Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China Graduate School of the Chinese Academy of Sciences, Beijing 100039, China | 2005 | Science China Earth Sciences2005，48，z1： | 3 |
| 6 | Attenuation ofβ-Amyloid Toxicity In Vitro and In Vivo by Accelerated Aggregation显示文摘Accumulation and aggregation of β-amyloid(Aβ) peptides result in neuronal death, leading to cognitive dysfunction in Alzheimer's disease. The self-assembled Aβ molecules form various intermediate aggregates including oligomers that are more toxic to neurons than the mature aggregates, including fibrils. Thus, one strategy to alleviate Aβ toxicity is to facilitate the conversion of Aβ intermediates to larger aggregates such as fibrils. In this study, we designed a peptide named A3 that significantly enhanced the formation of amorphous aggregates of Aβ by accelerating the aggregation kinetics. Thioflavin T fluorescence experiments revealed an accelerated aggregation of Aβ monomers, accompanying reduced Aβ cytotoxicity. Transgenic Caenorhabditis elegans over-expressing amyloid precursor protein exhibited paralysis due to the accumulation of Aβ oligomers, and this phenotype was attenuated by feeding the animals with A3 peptide. These findings suggest that the Aβ aggregation-promotion effect can potentially be useful for developing strategies to reduce Aβ toxicity. | Aihua Yang Chenxuan Wang Baomin Song Wendi Zhang Yuanyuan Guo Rong Yang Guangjun Nie Yanlian Yang Chen Wang | 2017 | Neuroscience Bulletin2017，33，4： | 3 |
| 7 | Vacuum-tuned-atmosphere induced assembly of Au@Ag core/shell nanocubes into multi-dimensional superstructures and the ultrasensitive IAPP proteins SERS detection显示文摘Utilizing vacuum-tuned-atmosphere induced dip coating method,we achieve the cross-dimensional macroscopic diverse self-assemblies by using one building block with one chemical functionality.Coordinated modulating the vacuum degree,colloid concentration and evaporation atmosphere,Au@Ag core/shell nanocubes (NCs) can controllably assemble into diverse multi-dimensional superstructures.Under 0.08 MPa,we obtained the two-dimensional (2D) stepped superstructures with continuously tunable step width.In addition,we generated a series of tailorable nanoscale-roughened 2D Au@Ag NCs superstructures at 0.04 MPa,which exhibited the label-free ultrasensitive SERS detection for the different mutants of IAPP8-37 proteins.Under 0.01 MPa,we obtained the cross-dimensional tailorable Au@Ag NCs assemblies from random to macroscale 2D and three-dimensional (3D) densest superstructures by adjusting the capping ligand-environmental molecule interactions.This is a flexible method to generate as-prepared Au@Ag core/shell NCs into well-defined macroscopic diverse superstructures and to promote the exploitation into biological applications. | Meng Xu Guopeng Tu Muwei Ji Xiaodong Wan Jiajia Liu Jia Liu Hongpan Rong Yanlian Yang Chen Wang Jiatao Zhang | 2019 | Nano Research2019，12，6： | 3 |
| 8 | A GLOBALLY AND SUPERLINEARLY CONVERGENT TRUST REGION METHOD FOR LC^1 OPTIMIZATION PROBLEMS显示文摘A new trust region algorithm for solving convex LC 1 optimization problem is presented.It is proved that the algorithm is globally convergent and the rate of convergence is superlinear under some reasonable assumptions. | Zhang Liping Lai Yanlian Institute of Applied Mathematics,Academia Sinica,Beijing 100080. | 2001 | Applied Mathematics(A Journal of Chinese Universities)2001，16，1： | 1 |
| 9 | Micro-tribologic Properties of a Covalently Attached Nanostructured Self-Assembly Film Fabricated from Fullerene Carboxylic Acid and Diazoredin显示文摘 | Cao Tingbing Wei Fang Yang Yanlian | 2002 | Langmuir2002，18，： | 1 |
| 10 | A rapid ap- proach to urushiol - copper (I) coordination polymer under UV irradiation 显示文摘 | Jianrong Xia Yanlian Xu Binghuan Hu | 2009 | Progress in Organic Coatings2009，65，4： | 1 |
| 11 | Designer self-assembling peptide nanomaterials显示文摘 | Yang Yanlian Khoe Ulung Wang Xiumei Akihiro Horii Hidenori Yokoi Zhang Shuguang | 2009 | Nano Today2009，，2： | 1 |
| 12 | Lectric-field- enhanced assembly of single-walled carbon nanotubes on a solid surface显示文摘 | Chen Zhuo Yang Yanlian Wu Zhongyun | 2005 | Journal of Physical Chemistry B2005，109，： | 1 |
| 13 | Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7显示文摘Dear Editor,The COVID-19 pandemic caused by SARS-CoV-2 has led to acute respiratory distress syndrome(ARDS)with a high rate of death.An excessive inflammatory response,caused by virus infection,is associated with severe clinical manifestations that may lead to death of patients.1 Therefore,the blockage of virus replication and suppression of hyper-inflammatory response are beneficial for COVID-19 treatment.However,the drug targeting both virus and hyper-inflammation,as far as we know,is not available yet. | Chen Xie Yanlian Chen Dongling Luo Zhen Zhuang Heping Jin Haoxian Zhou Xiaocui Li Haijun Lin Xiaohui Zheng Jing Zhang Peihui Wang Jincun Zhao Yong Zhao Hui Huang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 14 | Partitioning of evapotranspiration and its controls in four grassland ecosystems: Application of a two-source model 显示文摘 | Hu Zhongmin Yu Guirui Zhou Yanlian | 2009 | Agricultural and Forest Meteorology2009，149，9： | 1 |
| 15 | Magnetocon- ductance of polymer-fullerene bulk heterojunction solar cells显示文摘 | Le Yanlian Song Qunling Zhang Yong | 2009 | (Organic Eleetronics)Org Electron2009，10，： | 1 |
| 16 | Partitioning of evapotranspiration and its controls in four grassland ecosystems:application of a two-source model显示文摘 | Hu Zhongmin Yu Guiruia Zhou Yanlian | 2009 | Agricultural and Forest Meteorology2009，149，： | 1 |
| 17 | A unified approach to the method of gradient projection with arbitrary initialpoint显示文摘 | LAI Yanlian WEI Zengxin | 1991 | Journal of Systems Science and Complexity1991，3，4： | 1 |
| 18 | Peptide recognition by functional supramolecular nanopores with complementary size and binding sites显示文摘在单个分子的水平在表面上吸附的 biomolecules 的符合构造的精确控制是重要的。然而,因为复杂结构和 biomolecules 的符合构造差异,它仍然是巨大的挑战。此处,限制 nanopore 的识别策略被建议通过 functionalized 的精确设计在房间温度操作单个 valinomycin 分子的吸附结合的 macrocycle (CPN8 ) 有互补体系结构和有约束力的地点的超分子的 nanopores。我们表明 CPN8 与因为在 valinomycin 的 isopropyl 组和 CPN8 的氨基的组之间的强壮的 synergistic 相互作用,有选择地与互补建筑学认出 valinomycin 比比较喜欢,与 valinomycinhighly 面向的 pyrolytic 石墨(HOPG ) 相互作用。我们在单个分子的水平的观点将提供珍贵卓见为非结合的分子的符合构造选择的识别改进超分子的 nanopores 的设计。 | Yumin Chen Hui Nie Ke Deng Shili Wu Jindong Xue Lijin Shu Yue Yu Yanfang Geng Ping Li Yanlian Yang Qingdao Zeng | 2016 | Nano Research2016，9，5： | 1 |
| 19 | Prepa- ration of water-soluble hyperbranched polyester nanop articles with sulfonic acid functional groups and their mi cellos behavior,anticoagulant effect and cytotoxicity显示文摘 | Qiaorong Han Xiaohan Chen Yanlian Niu | 2013 | Langmuir2013，29，26： | 1 |
| 20 | Site-specific determination of TTR-related functional peptides by using scanning tunneling microscopy显示文摘为功能的肽的设计和优化, unravelling 单个积木的结构以及整体的性质是首要的。TTR1,源于人的 transthyretin,形成纤丝的肽在象家庭淀粉的 polyneuropathy 和老年的全身的淀粉样变性病那样的疾病被含有。基于 TTR1 脚手架,功能的肽 TTR1-RGD 被设计明确地与房间交往。这里,我们过去常扫描通道显微镜学(STM ) 与反向的顺序和修改前面的顺序分析 TTR1 相关的肽的集会结构。sitespecific 分析显示出下列:我) TTR1 肽涉及汇编,将近在订的表以内盖住全部长度组织。ii ) 为 TTR1-RGD 肽集会,当 RGDS 主题采用允许它支持房间粘附的灵活符合构造时, TTR1 主题形成订的表。关键地点清楚地作为连接器残余 Gly13 被识别。iii ) 尽管有在化学的差别,他们显示类似的集合的前面、反向的肽集会表演的仔细的检查特征,说明这些肽的柔韧的性质。iv ) Glycine 连接器残余在强烈建议顺序能被增加更多的连接器残余优化的 -strands, 被包括。进这些肽的装配结构的这些积累的卓见帮助解开驾驶肽集会的机制并且在新窗户中指示 sequenceprogrammed 肽 architectures.Open | Lanlan Yu Yongfang Zheng JingXu Fuyang Qu Yuchen Lin Yimin Zou Yanlian Yang Sally L. Gras Chen Wang | 2018 | Nano Research2018，11，1： | 1 |
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